Tumor suppressor protein

Rubin Group



2D 1H-15N TROSY spectrum of a 35 kDa tumor suppressor protein at 900 MHz. The sample was both 15N- and 2H-labeled.



2D 1H-15N HSQC spectrum of the same 35 kDa tumor suppressor protein at 600 MHz. The sample was 15N-labeled, but not deuteriated.  At lower field and without deuteriation, the sample quality is much worse.  The combination of deuteriation and availability of the 900 MHz instrument makes this project possible.