Bay Area 900MHz NMR Facility

The Central California 900 MHz NMR Facility, operated by Dr. Jeff Pelton and the Wemmer Lab, is a core facility that helps promote the understanding of the structures and dynamics of natural products, potential theraputics, proteins, and nucleic acids at the atomic level. Instruments include a state-of-the-art 900 MHz spectrometer equipped with a cryoprobe, and an 800 MHz spectrometer equipped with a room temperature probe. Access is available to investigators from QB3 as well as those at both academic and non-academic institutions on a recharge basis.

Video Introduction

A short introductory video to the 900MHz NMR Facility can be found here.

Check the 900 MHz Calendar for available magnet time.
Email Dr. Jeff Pelton to sign-up (jgpelton at berkeley dot edu)

Sample Data

Click here to see sample data from the 900 MHz in collaboration with researchers in the Bay Area.

Rut pathway for degradation of uracil

The system, known as the rut operon, consists of seven previously uncharacterized proteins which are involved in the conversion of uracil to ammonia, carbon dioxide,and 3-hydroxypropionic acid.  We used mass spectroscopy and NMR spectroscopy to characterize the product of the first enzyme in the pathway, Rut A, using uracil as the starting compound. More information on this project can be found here.