| 221. Michalak, D.J., Xu,
S., Lowery, T.J., Crawford, C.W., Ledbetter,
M., Wemmer, D.E., Budker, D., Pines, A.
“Relaxivity of Gadolinium Complexes Detected
by Atomic Magnetometry” Mag Res Med. (2011). |
| 220. Wickliffe, K.E., Lorenz,
S., Wemmer, D.E., Kuriyan, J., Rape, M. “The
mechanism of linkage-specific ubiquitin
chain elongation by a single-subunit E2”
Cell 144, 769-81 (2011). |
| 219. Hernandez, J.A., Phillips,
A.H., Erbil, K.W., Zhao, D., Zeymer, C.,
Pelton, J.G., Wemmer, D.E., Rubio, L.M.
“Nitrogenase recruits a SAM (Sterile Alpha
Motif) interaction domain: cofactor
insertion involves metallocluster-binding
and SAM-interaction domains” J Biol Chem.
286, 6321-28 (2011). |
| 218. Damo,
S.M., Phillips, A.H., Young, A.L., Li, S.,
Woods, V.L.Jr., Wemmer, D.E. “Probing the
Prion Protein Conformation in a Fibril with
Hydrogen Exchange” J.Biol.Chem.
285, 32303-11 (2010). |
| 217. Schilling, F., Schröder,
L., Palaniappan, K.K., Zapf, S., Wemmer,
D.E., Pines, A. “MRI Thermometry Based on
Encapsulated Hyperpolarized Xenon” Chem Phys
Chem 11, 3529-33 (2010). |
| 216. Wetzler, M., Wemmer, D.E.
“Facile Dimer Synthesis for DNA-binding
Polyamide Ligands” Org. Lett. 12, 3488-90
(2010). |
| 215. Meldrum, T., Schröder, L.,
Denger, P., Wemmer, D.E., Pines, A.
“Xenon-based Molecular Sensors in Lipid
Suspensions” J. Magn. Res. 205, 242-46
(2010). |
| 214. Kim, K.-S., Pelton, J.G.,
Andersen, U., Kustu, S. and Wemmer, D.E.
“The Rut pathway for pyrimidine degradation:
Novel chemistry and toxicity problems” J.
Bact. 192, 4089-102 (2010). |
| 213. Meldrum, T., Seim, K.L.,
Bajaj, V.S., Palaniappan, K., Wu, W.,
Francis, M.B., Wemmer, D.E., Pines, A. “A
Xenon-based Molecular Sensor Assembled on an
MS2 Viral Capsid Scaffold”
J.Am.Chem.Soc. 132, 5936-37 (2010). |
| 212. Sterling, H.J., Batchelor,
J.D., Wemmer, D.E. and Williams, E.R.
“Electrospray Ionization Mass Spectrometery
of a Non-Covalent Protein Complex with
Essential Salts via Buffer Loading” J. Am.
Soc. Mass. Spec. 21, 1045-49 (2010). |
| 211. Cetinkol, O.P., Dibble,
D.C., Cheng, C., Kent, M.S., Knierim, B.,
Auer, M., Wemmer, D.E., Pelton, J.G.,
Melnichenko, Y.B., Ralph, J., Simmons, B.A.
and Holmes, B.M. “Understanding the Impact
of Ionic Liquid Pretreatment on Eucalyptus” Biofuels 1, 33-46
(2010). |
| 210. Erbil,
W.K., Price, M.S., Wemmer, D.E. and
Marletta, M.A. “A structural basis for H-NOX
signaling by trapping a kinase inhibitory
conformation of the H-NOX from S.oneidensis”
Proc.Natl.Acad.Sci.USA 106, 19753-60 (2009). |
| 209. Inwood, W., Hall, J. Kim,
K.-S., Demirkahyan, L., Wemmer, D.E.,
Zgurskaya, H., Kustu, S. “Epistatic Effects
of the Protease/Chaperone HflB on Soe
Damaged Froms of the Escherichia coli
Ammonium Channel AmtB”
Genetics 183, 1327-1340 (2009). |
| 208. Batchelor, J.D., Sterling,
H.J., Hong, E., Williams, E.R., Wemmer, D.E.
“Receiver domains control the active state
stoichiometry of Aquifex aeolicus s54 activator NtrC4, as
revealed by electrospray mass
spectrometry” J. Mol. Biol. 393, 634-43
(2009). |
| 207. Jura, N., Endres, N.F.,
Engel, K., Deindl, S., Das, R., Lamers,
M.H., Wemmer, D.E., Zhang, X., Kuriyan, J.
“Structural coupling between the
juxtamembrane segment of the EGF receptor
and activation of the catalytic domain” Cell
237, 1293-1307 (2009). |
| 206. Hong, E., Doucleff, M. and
Wemmer, D.E. “Structure of the
RNA-Polymerase Core Binding Domain of s54 Reveals a Potential
Conformational Fracture Point” J. Molec.
Biol. 390, 70-82 (2009). |
| 205. Ledbetter, M.P., Crawford,
C.W., Pines, A., Wemmer, D.E., Knappe, S.,
Kitching, J. and Budker, D. “Optical
detection of scalar coupling at zero
magnetic field” J
Magn Res. 199, 25-29 (2009). |
| 204. Buhrlage, S.J., Bates,
C.A., Rowe, S.P., Minter, A.R., Brennan,
B.B., Majmudar, C.Y., Wemmer, D.E.,
Al-Hashimi, H. and Mapp, A.K. “Small
molecule transcriptional activation domains
interact with endogenous coactivators” ACS
Chem Bio 4, 335-344 (2009). |
| 203.
Batchelor, J.D., Doucleff, M. Lee, C.J.,
Matsubara, K., DeCarlo, S., Heideker, J.,
Lamers, M.H., Pelton, J.G., Wemmer, D.E.
“Structure and regulatory mechansim of A.
aeolicus NtrC4: variability and evolution in
bacterial transcriptional regulation” J. Molec.
Biol. 384, 1058-75 (2008). |
| 202. Schröder, L., Chavez, L.,
Meldrum, T., Smith, M., Lowery, T.J.,
Wemmer, D.E. and Pines, A.
“Temperature-Controlled Molecular
Depolarization Gates in Nuclear Magnetic
Resonance” Angew. Chem. Int Ed Engl 47,
4316-20 (2008). |
| 201. Schröder, L., Meldrum, T.,
Smith, M., Lowery, T.J., Wemmer, D.E. and
Pines, A. “Temperature response of 129Xe depolarization transfer
and application for unltra-sensitive NMR
detection” Phys. Rev. Letters. 100: 257603
(2008) |
| 200. Fawzi, N.L., Phillips, A.,
Ruscio, J.Z., Doucleff, M., Wemmer, D.E. and
Head-Gordon, T. “Structure and Dynamics of
the Ab21-30 Peptide from the Interplay
of NMR Experiments and Molecular
Simulations.” J. Am. Chem. Soc. 130,
6145-58 (2008). |
| 199. Baxter, N.J., Blackburn,
G.M., Marston, J.P., Hounslow, A.M., Cliff,
M.J., Bermel, W., Hollfelder, F., Williams,
N.H., Wemmer, D.E., Waltho, J.P. “Anionic
Charge is Prioritized over Geometry in
Aluminum and Magnesium Fluroide Transition
State Analogs of Phosphoryl Transfer
Enzymes” J. Am. Chem. Soc. 130, 3952-58
(2008). |
| 198. Lowery,
T.J., Pelton, J.G., Chandonia, J.-M., Kim,
R., Yokota, H., Wemmer, D.E. “NMR Structure
of the N-terminal domain of the replication
initiator protein DnaA” J. Str. Funct.
Genomics 8, 11-17 (2007). |
| 197. Matsuda, S., Fillo, J.D.,
Henry, A.A., Wilkens, S.J., Rai, P., Dwyer,
T.J., Beierstanger, B.H., Wemmer, D.E.,
Schultz, P.G., Spraggon, G., Romesberg,
F.E., “Efforts Toward Expansion of the
Genetic Alphabet: Determinants of Efficient
Replication of Unnatural Base Pairs” J. Am.
Chem. Soc. 129, 10466-73 (2007). |
| 196. Fraser, J.S., Merlie, J.P.
Jr., Echols, N., Weisfield, S.R., Mignot,
T., Wemmer, D.E., Zusman, D, Alber, T. “The
atypical receiver domain of Myxococcus
xanthus FrzS controls social motility
without aspartic-acid phosphorylation” Molec
Micro. 65, 319-322 (2007). |
| 195. Doucleff, M., Pelton, J.G.,
Lee, P.S., Nixon, B.T. and Wemmer, D.E.
“Structural Basis for DNA Recognition by the
Alternative Sigma-Factor, s54”
J. Molec. Biol. 369, 1070-1078
(2007). |
| 194. Chen, B., Doucleff, M.,
Wemmer, D.E., DeCarlo, S., Huang, H.,
Nogales, E., Hoover, T.R., Kondrashkina, E.,
Nixon, B.T. “ATP-ground and transition
states of the NtrC1 AAA+ ATPase support
binding to its target, s54” Structure 15,
429-440 (2007). |
| 193. Simon, M.D., Feldman, M.E.,
Maris, A.E. Wemmer, D.E. & Shokat, K.M.
“A re-engineered protein-DNA interface: The
development, structure and properties of a
homeodomain that recognizes an unnatural
nucleotide” ACS Chem. Biol. 1, 755-60
(2007). |
| 192. Tang, Y., Hwang, J.S.,
Wemmer, D.E., Keasling, J.D. “Quantitative
Investigation of Central Metabolic Pathways
in Shewanella oneidensis MR-1 under
Carbon-Limited and Oxygen-Limited Aerobic
Conditions using 13C-NMR and GC-MS” J. Appl.
Microbiology 73, 718-29 (2007). |
| 191. Garcia, S., Chavez, L.,
Lowery, T.J., Han, S.-I., Wemmer, D.E. and
Pines, A. “Sensitivity Enhancement by
Exchange Mediated Magnetization Transfer of
the Xenon Biosensor Signal” J. Mag. Reson.
184, 72-77 (2007). |
| 190.
Schröder, L., Lowery, T.J., Hilty, C.,
Wemmer, D.E. and Pines, A. “Molecular
Imaging using a Targeted Magnetic Resonance
Hyperpolized Biosensor” Science 314, 449-53
(2006). |
| 189. Pirruccello, M.,
Sondermann, H., Pelton, J.G., Pellicena, P.,
Hoelz, A., Chernoff, J., Wemmer, D.E.,
Kuriyan, J. “A Dimeric Kinase Assembly
Underlying Autophosphorylation in the p21
Activated Kinases” J.Molec.Biol. 361,
312-326 (2006). |
| 188. Mynar, J.L., Lowery, T.J.,
Wemmer, D.E., Pines, A., Fréchet, J.M.J.
“Xenon Biosensor Amplification via
Dendrimer-Cage Supramolecular Constructs”
J.Am.Chem.Soc. 128, 6334-5 (2006). |
| 187. Roberts, A., Pelton, J.G.
and Wemmer, D.E. “Structural Studies of
MJ1529, an O6-methylguanine-DNA
Methyltransferase” Magn. Res. Chem. 44,
71-82 (2006). |
| 186. Lowery, T.J., Garcia, S,
Chavez, L., Ruiz, E.J., Wu, T, Brotin, T.,
King, D.S., Schultz, P.G., Pines, A. and
Wemmer, D.E. “Optimization of Xenon
Biosensors for Detection of Protein
Interactions” ChemBioChem. 7, 65-73 (2006). |
| 185. Lim, K.-H., Nguyen, T.N.,
Damo, S.M., Mazur, T., Ball, H.L., Prusiner,
S.B., Pines, A. and Wemmer, D.E. “Solid
State NMR Structural Studies of the Fibril
form of a Mutant Mouse Prion Peptide PrP89-143(P101L)”
Solid State NMR 29, 183-190 (2006). |
| 184. Hilty, C., Lowery, T.J.,
Wemmer, D.E. and Pines, A. “Spectrally
Resolved Magnetic Resonance Imaging of a
Xenon Biosensor” Angew. Chemie 45, 70-73
(2006). |
| 183.
Doucleff, M.C., Malak, L.T., Pelton, J.G.
and Wemmer, D.E. “The C-terminal RpoN Domain
of s54 Forms an Unpredicted
Helix-Turn-Helix Motif Similar to Domains
of s70” J. Biol. Chem. 280,
41530-36 (2005). |
| 182. Nixon, B.T., Yennawar,
H.P., Doucleff, M., Pelton, J.G., Wemmer,
D.E., Kreuger, S. and Kondrashkina, E. “SAS
Solution Structures of the Apo and Mg+2/BeF3- bound Receiver Domain of
DctD from Sinorhizobium meliloti” Biochem.
44, 13962-69 (2005) |
| 181. Doucleff, M., Chen, B.,
Maris, A.E., Wemmer, D.E. Kondrashkina E.
and Nixon, B.T. “Regulation of AAA+ ATPase
Assembly by Two Component Receiver Domains:
A Transcription Activation Mechanism that is
Conserved in Mesophilic and Extremely
Hyperthermophilic Bacteria”, J. Mol. Biol.
353, 242-55 (2005). |
| 180. Choi, Y.-J., Ryu, K.-S.,
Ko, Y.-M., Chae, Y.-K., Pelton, J.G.,
Wemmer, D.E., Choi, B.-S. “Biophysical
characterization of the interaction domains
and mapping of the contact residues in the
XPF-ERCC1 complex” J. Biol. Chem. 280,
28644-28652 (2005) |
| 179. Kim, H.-S., Damo, S.M.,
Lee, S.-Y., Wemmer, D.E. and Klinman, J.P.
“Structure and Hydride Transfer Mechanism of
a Moderate Thermophilic Dihydrofolate
Reductase from B. Stearothermophilus and
Comparision with Its Mesophilic and
Hyperthermophilic Homologs” Biochem. 44,
11428-11439 (2005). |
| 178. Han, S.I., Garcia, S.,
Lowery, T.J., Ruiz, E.J., Seeley, J.A.,
Chavez, L., King, D.S., Wemmer, D.E. &
Pines, A. “NMR-Based Bio-Sensing with
Optimized Delivery of Polarized 129Xe to Solutions” Analyt
Chem. 77, 4008-4012 (2005) |
| 177. Pelton, J.G., Shi, J.,
Yokota, H., Kim, R. and Wemmer, D.E. “NMR
structure of hypothetical protein MG354 from
Mycoplasma genetalium” Proteins 61, 666-668
(2005). |
| 176. Lowery, T.J., Doucleff, M.,
Ruiz, E.J., Rubin, S.M., Pines, A. and
Wemmer, D.E. "Distinguishing Multiple
Chemotaxis Y Protein Conformations with
Laser-Polarized 129Xe NMR" Prot. Sci. 14,
848-855 (2005). |
| 175. Rai, P., Wemmer, D.E.,
Linn, S. “Preferential binding and
structural distortion by Fe2+ at RGGG-containing DNA
sequences correlates with enhanced
oxidative cleavage at such sequences” Nuc.
Acids Res. 33, 497-510 (2005). |
| 174. Roberts, A., Lee, S.-Y.,
McCullagh, E., Silversmith, R.E. and Wemmer,
D.E. “YbiV from E.coli K12 is a HAD
Phosphatase” Proteins 58, 790-801 (2005). |
| 173. Spence,
M.M., Ruiz, E.J., Rubin, S.M., Lowery, T.J.,
Winssinger, N., Schultz, P.G., Wemmer, D.E.
and Pines, A. “Development of a
Functionalized Xenon Biosensor”
J.Am.Chem.Soc. 126, 15287-15294 (2004). |
| 172. Lowery, T.J., Rubin, S.M.,
Ruiz, E.J., Pines, A. and Wemmer, D.E.
“Design of a Conformation-Sensitive
Xenon-Binding Cavity in the Ribose Binding
Protein” Angew. Chemie 43, 6320-6322 (2004). |
| 171. Zhang, Q., Dwyer, T.J.,
Tsui, V., Case, D.A., Cho, J., Dervan, P.B.
and Wemmer, D.E. “NMR Structure of a Cyclic
Polyamide-DNA Complex” J.Am.Chem.Soc. 126,
7958-7966 (2004). |
| 170. Shi, J. Pelton, J.G., Cho,
H.S. & Wemmer, D.E. “Protein Signal
Assignments using Specific Labeling and
Cell-free Synthesis” J. Biomol. NMR. 28,
235-247 (2004). |
| 169. Rubin,
S.M., Pelton, J.G., Yokota, H., Kim, R.
& Wemmer, D.E. “Solution Structure of a
Putative Ribosome Binding Protein from
Mycoplasma pneumoniae and Comparison to a
Distant Homolog” J. Struct. Funct. Gen. 4,
235-243 (2003). |
| 168. Lowery, T.J., Rubin, S.M.,
Ruiz, E.J., Spence, M.M., Winssinger, N.,
Schultz, P.G., Pines, A. & Wemmer, D.E.
“Applications of laser-polarized 129Xe to biomolecular assays”
Magn. Res. Imaging 21, 1235-1239 (2003). |
| 167. Lee, S.Y., de la Torre, A.,
Yan, D., Kustu, S., Nixon, B.T. &
Wemmer, D.E. “Regulation of the
transcriptional activator NtrC1: structural
studies of the regulatory and AAA+ ATPase Domains” Genes &
Development 17, 2552-2563 (2003). |
| 166. Nguyen, T.N. and Wemmer,
D.E. “Complete resonance assignments for the
Nudix hydrolase DR2356 of Dienococcus
radiodurans” J. Biomol. NMR 27, 181-182
(2003). |
| 165. Hastings, C.A., Lee, S.-Y.,
Cho, H.S., Yan, D. Kustu, S and Wemmer, D.E.
“High Resolution Solution Structure of the
Beryllofluoride-Activated NtrC Receiver
Domain” Biochemistry 42, 9081-9090 (2003). |
| 164. Gardino, A., Volkman, B.,
Cho, H.S., Lee, S.Y., Wemmer, D.E. and Kern,
D. “The NMR Solution Structure of
BeF3-Activated Spo0F reveals the
conformational switch in a phosphorelay
system” J. Mol. Biol. 331, 245-254 (2003). |
| 163. Shin, D.-H., Roberts, A.,
Jancarik, J., Yokota, H., Kim, R., Wemmer,
D.E. & Kim, S.-H. “Crystal structure of
a phosphase with a unique substrate binding
domain from Thermatoga maritima” Prot. Sci.
12, 1464-1472 (2003). |
| 162. Hawkins,
C.A., Baird, E.E., Dervan, P.B. and Wemmer,
D.E. “Analysis of Hairpin Polyamide
Complexes Having DNA Binding Sites in Close
Proximity” J.Am.Chem.Soc. 124, 12689-12696
(2002). |
| 161. Rubin, S.M., Lee, S.-Y.,
Ruiz, E.J., Pines, A. and Wemmer, D.E.
“Detection and Characterization of Xenon
Binding Sites in Protein by 129Xe
NMR Spectroscopy” J. Mol. Biol. 322,
425-440 (2002). |
| 160. Lim, K.H., Nguyen, T.,
Mazur, T., Wemmer, D.E. and Pines, A.
“Sensitivity Enhancement in Multiple-Quantum
NMR with CPMG Detection”,
J. Magn. Reson. 157, 160-162 (2002). |
| 159. Supekova, L., Pezacki,
J.P., Su, A., Loweth, C.J., Reidl, R.,
Geierstanger, B.H., Massari, E., Murre, C.,
Wemmer, D.E. and Schultz, P.G. “Genomic
Characterization of Polyamide/DNA
Interactions in Cells” Chemistry &
Biology 9, 821-827 (2002). |
| 158. Liu,
K., Kelly, J.W. and Wemmer, D.E. “A Hydrogen
Exchange Study of Suppressor and Pathogenic
Variants of Transthyretin” J. Mol. Biol.
320, 821-832 (2002). |
| 157. Wang, W., Cho, H.S., Kim,
R., Jancarik, J., Yokota, H., Nguyen, H.T.,
Grigoriev, I.V., Wemmer, D.E. and Kim, S.-H.
“Structural Characterization of the Reaction
Pathway in Phosphoserine Phosphatase:
Crystallographic ‘Snapshots’ of Intermediate
States” J. Mol. Biol. 319, 421-431 (2002). |
| 156. Westler, W.M., Frey, P.A.,
Lin, J., Wemmer, D.E., Morimoto, H.,
Williams, P.G. and Markley, J.L. “Evidence
for a Strong Hydrogen Bond in the Catalytic
Dyad of Transition State Analog Inhibitor
Complexes of Chymotrypsin from Proton-Triton
NMR Isotope Shifts” J. Am. Chem. Soc. 124,
4196-97 (2002). |
| 155. Havlin,
R.H., Laws, D.D., Bitter, H.-M.L., Sanders,
L.K., Sun, H., Grimley, J.S., Wemmer, D.E.,
Pines, A. & Oldfield, E. “An
Experimental and Theoretical Investigation
of the Chemical Shielding Tensors of 13Ca of Alanine, Valine and
Leucine Residues in Solid Peptides and in
Proteins in Solution” J. Am. Chem. Soc.
123, 10362-69 (2001). |
| 154. Rai, P., Cole, T.D.,
Wemmer, D.E. & Linn, S. “Differences in
the conformation of bases within a duplex
ATGA sequence explain preferential cleavage
by Fe2+ and H2O2: Studies by Nuclear
Magnetic Resonance Spectroscopy”
J.Mol.Biol. 312, 1089-1101 (2001). |
| 153. Spence, M.M., Rubin, S.M.,
Dimitrov, I.E., Ruiz, E.J., Wemmer, D.E.,
Pines, A., Yao, S.Q., Tian, F. &
Schultz, P.G. “Functionalized Xenon as a
Biosensor” Proc.Natl.Acad.Sci. 98,
10645-10657 (2001). |
| 152. Rubin, S.M., Spence, M.M.,
Dimitrov, I.E., Ruiz, E.J., Pines, A. &
Wemmer, D.E. “Detection of a Conformational
Change in Maltose Binding Protein by 129Xe NMR” J.Am.Chem.Soc. 123,
8616-17 (2001). |
| 151. Laws, D.D., Bitter,
H.-M.L., Ball, H.L., Prusiner, S.B., Wemmer,
D.E. & Pines, A. “Solid-state
NMR Studies of the Secondary Structure of
Peptides Comprising Residues 89-143 of the
Prion Protein” Proc.Natl.Acad.Sci. 98,
11686-11690 (2001). |
| 150. Rubin, S.M., Spence, M.M.,
Wemmer, D.E. & Pines, A.
“Characterization of the Effects of
Nonspecific Xenon-Protein Interactions on 129Xe Chemical Shifts in
Aqueous Solution: Further Development of
Xenon as a Biomolecular Probe” J. Magn.
Res. 152, 79-86 (2001). |
| 149. Cho, H., Wang, W., Kim, R.,
Yokota, H., Damo, S., Kim, S.-H., Wemmer,
D.E., Kustu, S. & Yan, D. “BeF3- acts as a phosphate analog
in proteins phosphorylated on aspartate:
structure of a BeF3- complex with phosphoserine
phosphatase” Proc. Natl. Acad. Sci. 98,
8525-8530 (2001). |
| 148. Zhang, Q., Harada, K., Cho,
H.S., Frankel, A. and Wemmer,
D.E. “Structural Characterization
of the Complex of the Rev Response Element
RNA with a Selected Peptide” Chem. &
Biol. 8, 511-520 (2001). |
| 147. Lee,
S.-Y., Cho, H.S., Pelton, J.G., Yan, D.,
Berry, E. & Wemmer, D.E. “Crystal
Structure of Activated CheY: Comparison with
other Activated Receiver Domains” J. Biol.
Chem. 276, 16425-16431 (2001). |
| 146. Volkman, B.F., Lipson, D.,
Wemmer, D.E. & Kern, D. “Two-State
Allosteric Behavior in a Single-Domain
Signaling Protein” Science 291, 2429-2433
(2001). |
| 145. Cave,
J.W., Cho, H.S., Batchelder, A.M., Yokota,
H., Kim, R. & Wemmer, D.E. “Solution NMR
Structure of a Protein Disulfide
Oxidoreductase from Methanococcus
jannaschii” Prot. Sci. 10, 384-396 (2001). |
| 144. Hawkins, C.A., Watson, C.,
Gong, B. & Wemmer, D.E. “Structural
analysis of the binding modes of minor
groove ligands comprised of disubstituted
benzenes” Nuc. Acids Res. 29, 936-942
(2001). |
| 143. Bastos, M., Pease, J.H.B.,
Wemmer, D., Murphy, K.P. and Connelly, P.R.
“Thermodynamics of the Helix-Coil
Transition. The
Binding of S15 and a Hybrid Sequence,
Disulfide Stabilized Peptide to the
S-Protein” Proteins: Str. Funct. Gen. 42,
523-530 (2001). |
| 142. Lee,
S.-Y., Cho, H.S., Hastings, C., Pelton,
J.G., Yan, D., Henderson, R.K., Huang,
L.-S., Kustu, S., Berry, E.A. & Wemmer,
D.E. “Crystal structure of an activated
response regulator bound to its target”
Nature Str. Biol. 8,
52-56 (2001). |
| 141. Cave,
J.W., Kermer, W. and Wemmer D.E. “Backbone
dynamics of sequence specific recognition
and binding by the Yeast Pho4 bHLH domain
probed by NMR” Prot. Sci. 9, 2354-2365
(2000). |
| 140. Rogers,
J.P., Pemberton-Goodman, K., Harty, P.,
Luginbühl, P., Wemmer, D.E. & Stevens,
R.C. “Structure-Activity Relationships in a
Peptidic a7 Nicotinic Acetylcholine Receptor
Agonist” J. Mol. Biol. 304, 911-926 (2000). |
| 139. Liu,
K., Cho, H.S., Hoyt, D.W., Nguyen, T., Olds,
P., Kelly, J.W. & Wemmer, D.E.
“Deuterium-Proton Exchange on the Native
Wild-Type Transthyretin Tetramer Identifies
the Stable Core of the Individual Subunits
and Indicates Mobility at the Subunit
Interface” J. Mol. Biol. 303, 555-565
(2000). |
| 138. Liu,
K., Cho, H.S., Lashuel, H.A., Kelly, J.W.
& Wemmer, D.E. “A glimpse of a possible
amyloidogenic intermediate of transthyretin”
Nature Str Biol. 7, 754-757 (2000). |
| 137. Rubin, S.M., Spence, M.M.,
Goodson, B.M., Wemmer, D.E. and Pines, A.
“Evidence of Nonspecific Surface
Interactions Between Laser-Polarized Xenon
and Myoglobin in Solution”
Proc.Natl.Acad.Sci. 97, 9472-5 (2000). |
| 136. Bolvig, S., Hansen, P.E.,
Morimoto, H.M., Wemmer, D.E. & Williams,
P.G. “Primary Tritium and Deuterium Isotope
Effects on Chemical Shifts of Compounds
Having an Intramolecular Hydrogen Bond” Magn. Res. Chem.
38, 525-535 (2000). |
| 135. Hawkins, C.A., de Clairac,
R.P., Dominey, R.N., Baird, E.E., White, S.,
Dervan, P.B. & Wemmer, D.E. “Controlling
Binding Orientation in Hairpin Polyamide DNA
Complexes” J.Am.Chem.Soc. 122, 5235-5243
(2000). |
| 134. Cho,
H.S., Lee, S.-Y., Yan, D., Pan, X.,
Parkinson, J.S., Kustu, S., Wemmer, D.E. and
Pelton, J.G. “NMR Structure of Activated
CheY” J. Molec. Biol. 297, 543-551 (2000). |
| 133. Robertson, S.A., Harada,
K., Frankel, A.D. & Wemmer, D.E.
“Structure Determination and Binding
Kinetics of a DNA Aptamer-Argininamide
Complex” Biochem. 39, 946-954 (2000). |
| 132. Keating, K.A., Myers, J.D.,
Pelton, J.G., Bair, R.A., Wemmer, D.E. and
Ellis, P.D. “Development and Use of a
Virtual NMR Facility” J. Magn. Reson. 143,
172-183 (2000). |
| 131. Kern,
D., Volkman, B.F., Luginbühl, P., Nohaile,
M.J., Kustu, S. and Wemmer, D.E. “Structure
of a transiently phosphorylated switch in
bacterial signal transduction” Nature 402,
894-898 (1999). |
| 130. Yan, D., Cho, H.S.,
Hastings, C.A., Lee, S.-Y., Pelton, J.G.,
Stewart, V., Wemmer, D.E. and Kustu, S.
“Beryllofluoride mimics phosphorylation of
NtrC and other bacterial response
regulators” Proc.
Natl. Acad. Sci. 96, 14789-14794 (1999). |
| 129. Bolvig, S., Hansen, P.E.,
Wemmer, D. and Williams, P.G. “Deuterium
Isotope Effects on 17O Chemical Shifts of
Intramolecularly Hydrogen Bonded Systems”
J. Struct. Chem. 509, 171-181 (1999). |
| 128. Pelton, J.G., Kustu, S. and
Wemmer, D.E. “Solution Structure of the DNA
Binding Domain of NTRC with Three Alanine
Substitutions” J. Molec. Biol. 292,
1095-1110 (1999). |
| 127. Cho,
C.Y., Liu, C.W., Wemmer, D.E. and Schultz,
P.G. “Cyclic
and linear oligocarbamate ligands for human
thrombin” Bioorg. Med. Chem. 7, 1171-1179
(1999). |
| 126. Rogers,
J.P., Luginbühl, P., Stevens, R.C. and
Wemmer, D.E. “NMR Solution Structure of
a-Conotoxin ImI and Comparison to other
Conotoxins Specific for Neuronal Nicotinic
Acetylcholine Receptors” Biochem. 38,
3874-3882 (1999). |
| 125. Peteranderl,
R., King, D., Rabenstein, M.D., Shin, Y.-K.,
Liu, C.W., Wemmer, D.E. & Nelson, H.C.M.
“Biochemical and Biophysical
Characterization of the Trimerization Domain
from the Heat Shock Transcription Factor”
Biochem. 38, 3559-3569 (1999). |
| 124. de
Clairac, R.P.L., Seel, C.J., Geierstanger,
B.H., Mrksich, M., Baird, E.E., Dervan, P.B.
& Wemmer, D.E. "NMR Characterization of
the Aliphatic b/b Pairing for Recognition of
A•T/T•A Base Pairs in the Minor Groove"
J.Am.Chem.Soc. 121, 2956-2964 (1999). |
| 123. Driggers,
E.M., Liu, C.W., Wemmer, D.E. & Schultz,
P.G. “Structure of the Michaelis Complex of
an Efficient Antibody Acyl Transferase
Determined by Transferred-NOESY”
J.Am.Chem.Soc. 120, 7395-7396 (1998). |
| 122. Gehring,
K. Zhang, X, Hall, J., Nikaido, H. &
Wemmer D.E. “An NMR Study of Ligand Binding
by Maltodextrin Binding Protein” Biochem.
& Cell Biol. 76, 189-176 (1998). |
| 121. Cho,
C.Y., Youngquist, R.S., Paikoff, S.J.,
Beresini, M.H., Hebert, A.R., Liu, C.W.,
Wemmer, D.E., Keough, T. & Schultz, P.G.
“Synthesis and Screening of Linear and
Cyclic Oligocarbamate Libraries. Discovery of High
Affinity Ligands for GPIIb/IIIa”
J.Am.Chem.Soc. 120, 7706-7718 (1998). |
| 120. Driggers,
E.M., Cho, H.S., Liu, C.W., Katzka, C.P.,
Braisted, A.C., Ulrich, H.D., Wemmer, D.E.
& Schultz, P.G. “Mechanistic
Studies of an Antibody-Catalyzed Pericyclic
Rearrangement” J.Am.Chem.Soc. 120, 1945-1958
(1998). |
| 119. Lee,
A.L., Volkman, B.F., Robertson, S.A.,
Rudner, D.Z., Barbash, D.A., Cline T.W.,
Kanaar, R., Rio, D.C. and Wemmer, D.E. “Chemical Shift
Mapping of the RNA-Binding Interface of the
multiple-RBD Protein Sex-Lethal” Biochem. 36,
14306-14317 (1997). |
| 118. Nohaile,
M.J., Kern, D., Volkman, B.F., Steadman,
K.S., Kustu, S. and Wemmer, D.E.
“Conformational Changes in the NTRC Receiver
Domain Upon Activation”
J.Mol.Biol. 273, 299-316 (1997). |
| 117. Hofmann,
M., Acedo, M., Fagan, P., Wemmer, D.,
Eritja, R. & Diaz, A.R. “Synthesis of
oligodeoxynucleotides containing
N6-[13C-methyl]adenine and
N2-[13C-methyl]guanine” J.Chem.Soc. Perkin
Trans. 1,
1825-1828 (1997). |
| 116. Austin,
R.E., Maplestone, R.A., Sefler, A.M., Liu,
K., Hruzewicz, W.N., Liu, C.W., Cho, H.S.,
Wemmer, D.E. & Bartlett, P.A. “A Template for
Stabilization of a Peptide a-Helix:
Synthesis and Evaluation of Conformational
Effects by Circular Dichroism and NMR”
J.Am.Chem.Soc. 119, 6461-6472 (1997). |
| 115. Heller,
J., Laws, D.D., King, D.S., Wemmer, D.E.,
Pines, A., Havlin, R.H., and Oldfield, E.
“Determination of dihedral angles in
peptides through experimental and
theoretical studies of alpha carbon chemical
shielding tensors” J.Am.Chem.Soc.
119, 7827-7831 (1997). |
| 114. Volkman,
B.F. & Wemmer, D.E.
"Deletion of a Single Amino Acid
Changes the Folding of an Apamin Hybrid
Sequence Peptide to that of Endothelin"
Biopolymers 41, 451-460 (1997). |
| 113. de Clairac, R.P.L.,
Geierstanger, B.H., Mrksich, M., Parks,
M.E., Dervan, P.B. & Wemmer, D.E. "NMR
Characterization of Designed "Hairpin"
Peptide Complexes with the Minor Groove of
DNA" J.Am.Chem.Soc. 119,
7909-7916 (1997). |
| 112. Braun, J., Schwesinger, R.,
Williams, P.G., Morimoto, H., Wemmer, D.E.
& Limbach, H.-H. "Kinetic H/D/T Isotope
and Solid State Effects on the Tautomerism
of the Conjugate Porphyrin Monoanion"
J.Am.Chem.Soc. 118, 11101-11110 (1996). |
| 111. Heller, J., Kolbert, A.C.,
Larsen, R., Ernst, M., Livshitz, T.,
Baldwin, M., Prusiner, S.G., Pines, A. &
Wemmer, D.E. "Solid-State NMR Studies of the
Prion Protein H1 Fragment" Prot. Science 5,
1655-61 (1996). |
| 110. Jaiswal, D.K., Morimoto,
H., Trump, E.L., Williams, P.G. &
Wemmer, D.E. "Synthesis of High Specific
Activity Tritium Labelled
[2-3H]-Adenosine-5'-Triphosphate" J. Labeled Cmpd.
Radiopharm. 38, 743-52 (1996). |
| 109. Heller, J., Larsen, R.,
Ernst, M., Kolbert, A.C., Baldwin, M.,
Prusiner, S.B., Wemmer, D.E. & Pines, A. "Application of
Rotational Resonance to Inhomogeneously
Broadened Systems" Chem. Phys. Lett. 251,
223-9 (1996). |
| 108. Kubinec, M.G., Culf, A.S.,
Cho, H., Lee, D.C., Burkham, J., Morimoto,
H., Williams, P.G. & Wemmer, D.E.
"Applications of Tritium NMR to
Macromolecules: A Study of Two Nucleic Acid
Molecules" J. Biomol. NMR. 7, 236-246
(1996). |
| 107. Braun,
J., Limbach, H.-H., Wemmer, D.E., Morimoto,
H. & Williams, P.G.
"Observation of Kinetic Tritium
Isotope Effects by Dynamic NMR : The
Tautomerism of Porphyrin"
J.Am.Chem.Soc. 118, 7231-32 (1996). |
| 106. Fagan,
P.A., Fàbrega, C., Eritja, R., Goodman, M.F.
& Wemmer, D.E. "An NMR Study of the
Conformation of the 2-Aminopurine:Cytosine
Mismatch in DNA" Biochem.
35, 4026-4033 (1996). |
| 105. Geierstanger,
B.H., Mrksich, M., Dervan, P.B. &
Wemmer, D.E. "Extending the Recognition Site
of Designed Minor Groove Binding Molecules"
Nature Structural Biology, 3, 321-324
(1996). |
| 104. Fagan,
P.A., Spielmann, H.P., Sigurdsson, S.Th.,
Hopkins, P.B. & Wemmer, D.E. "An NMR Study of
[d(CGCGAATTCGCG)]2 containing an Interstrand
Cross-Link Derived from a Distamycin Pyrrole
Conjugate" Nuc.
Acids Res. 24, 1566-73 (1996). |
| 103. Cho,
H.S., Liu, C.W., Damberger, F.F., Pelton,
J.G., Nelson, H.C.M., & Wemmer, D.E.
"Yeast Heat Shock Transcription Factor
Activation Domains are Unstructured as
Probed by Heteronuclear NMR Spectroscopy"
Protein Science 5, 262-269 (1996). |
| 102. Damberger,
F.D., Pelton, J.G., Liu, C., Cho, H.,
Harrison, C.J., Nelson, H.C.M. & Wemmer,
D.E. "Refined
Solution Structure of the DNA-binding Domain
of the Heat Shock Factor from Kluyveromyces
lactis" J. Molec. Biol. 254, 704 (1995). |
| 101. Liu,
H., Spielmann, H.P., Ulyanov, N.A., Wemmer,
D.E. & James, T.L. "Interproton Distance
Bounds from 2D-NOE Intensities: Effect of
Experimental Noise and Peak Integration
Errors" J.Biomol. NMR. 6, 390 (1995). |
| 100. Kanaar,
R., Lee, A.L., Rudner, D.Z., Wemmer, D.E.
& Rio, D.C. "Interaction
of the Sex-lethal RNA binding domains with
RNA" EMBO Journal 14, 4530 (1995). |
| 99. Spielmann,
H. P., Dwyer, T. J., Hearst, J.E. &
Wemmer, D.E. "The Solution Structures of
Psoralen Monoadducted and Crosslinked DNA
Oligomers by NMR Spectroscopy and Restrained
Molecular Dynamics" Biochem.
34, 12937 (1995). |
| 98. Spielmann,
H.P., Wemmer, D.E., Jacobsen, J.P. "The
Solution Structure of a DNA Complex with the
Fluorescent bis-intercalator TOTO determined
by NMR Spectroscopy" Biochemistry 34, 8542
(1995). |
| 97. Jacobsen, J.P., Pedersin,
J.B., Hansen, L.F. & Wemmer, D.E. "Site
selective bis-intercalation of a homodimeric
thiazole orange dye in DNA oligonucleotides"
Nuc. Acids Res. 23, 753 (1995). |
| 96. Spielmann,
P.H., Dwyer, T.J., Sastry, S., Hearst, J.E.
& Wemmer, D.E. "DNA Structural
Reorganization Upon Conversion of a Psoralen
Furanside Monoadduct to an Interstrand
Cross-Link: Implications for DNA Repair"
Proc. Natl. Acad. Sci. 92, 2345 (1995). |
| 95. Rentzeperis,
D., Marky, L.A., Dwyer, T.J., Geierstanger,
B.H., Pelton, J.G. & Wemmer, D.E.
"Interaction of Minor Groove Ligands to an
AAATT/TTTAA Site: Correlation of
Thermodynamic Characterization and Solution
Structure" Biochemistry
34, 2937 (1995). |
| 94. Volkman, B.F., Nohaile,
M.J.,Amy, N., Kustu, S., Wemmer, D.E.
"Three-Dimensional Solution Structure of the
N-Terminal Receiver Domain of NTRC"
Biochemistry 34, 1413 (1995). |
| 93. Spielmann,
H.P., Fagan, P.A., Bregant, T.M., Little,
R.D., Wemmer, D.E. "The Binding Modes of a
Rationally Designed Photoactivated DNA
Nuclease Determined by NMR" Nuc. Acids Res.
23, 1576 (1995). |
| 92. Lee,
A.L., Kanaar, R., Rio, D.C., Wemmer, D.E.
"Resonance Assignments and Solution
Structure of the Second RNA-Binding Domain
of Sex-lethal Determined by Multidimensional
Heteronuclear Magnetic Resonance"
Biochemistry 33, 13775 (1994). |
| 91. Geierstanger,
B.H., Mrksich, M., Dervan, P.B., Wemmer,
D.E. "Design of a G•C Specific DNA Minor
Groove Peptide" Science
266, 646 (1994). |
| 90. Acedo,
M., Fabrega, C., Avinó, Goodman, M., Fagan,
P., Wemmer, D.E., Eritja, R.
"A Simple Method for N-15 Labeling of
Exocyclic Amino Groups in Synthetic
Oligdeoxynucleotides" Nuc. Acids Res. 22,
2983 (1994). |
| 89. Damberger, F.D., Pelton,
J.G., Harrison, C., Nelson, H.C.M. &
Wemmer, D.E. "Solution Structure of the DNA
Binding Domain of the Heat Shock
Transcription Factor Determined by NMR"
Protein Science 3, 1806 (1994). |
| 88. Geierstanger, B.H., Volkman,
B.F., Kremer, W. and Wemmer, D.E. "Short
Peptide Fragments Derived from HMG-I/Y
Proteins Bind Specifically to the Minor
Groove of DNA" Biochemistry
33, 5347 (1994). |
| 87. Zhou, H.X., Lyu, P.C.,
Wemmer, D.E. & Kallenbach, N.R.
"Structure of a C terminal alpha helix cap
in a synthetic peptide" J.Am.Chem.Soc. 116,
1139 (1994). |
| 86. Singh, S.B., Ajay, Wemmer,
D.E. & Kollman, P.A. "Relative Binding
Affinities of Distamycin and its Analog to
d(CGCAAGTTGGC):d(GCCAACTTGCG).
Comparison of the theoretical
predictions with the experimental results" Proc.Natl.Acad.Sci.
91, 7673 (1994). |
| 85. Dwyer, T.J., Geierstanger,
B.H., Mrksich, M., Dervan, P.B., Wemmer,
D.E. "Structural Analysis of Covalent
Peptide Dimers,
Bis(Pyridine-2-carboxamide-netropsin)(CH2)3-6,
in Complex with 5'-TGACT-3' Sites by
Two-Dimensional NMR" J.Am.Chem.Soc.
115, 9900 (1993). |
| 84. Pagel,
M.D. and Wemmer, D.E. "Solution Structure of
a Minimal Sequence Peptide Derived from
Scyllatoxin" Proteins:
Str. Funct. Genet. 18, 205 (1994). |
| 83. Geierstanger, B.H.,
Jacobsen, J.P., Mrksich, M., Dervan, P.B.
and Wemmer, D.E. "Structural and Dynamic
Characterization of Heterodimeric and
Homodimeric Complexes of Distamycin and
1-Methylimidazole-2-carboxamide-netropsin
bound to the Minor Groove of DNA" Biochem. 33, 3055
(1994). |
| 82. Zhou, H.X., Lyu, P.C.,
Wemmer, D.E. and Kallenbach, N.R. "Alpha
Helix Initiation in Synthetic Model Peptides
by a Capping Box" Proteins: Str., Funct.
Genetics 18, 1 (1994). |
| 81. Emsley, L., Dwyer, T.J.,
Spielmann, H.P., Wemmer, D.E. "Determination
of Conformational Features in DNA from
Selective Two-Dimensional NMR Experiments"
J.Am.Chem.Soc. 115, 7765 (1993). |
| 80. Highsmith, S., Kubinec, M.,
Jaiswal, D.K., Morimoto, H., Williams, P.G.,
Wemmer, D.E. "[2-3H]ATP Synthesis and 3H-NMR
Spectroscopy of Enzyme Nucleotide Complexes:
ADP and ADP,Vi bound to myosin subfragment
1" J.Biomol.NMR 3, 325-334 (1993). |
| 79. Lyu, P.C., Wemmer, D.E.,
Zhou, H.X., Pinker, R.J., Kallenbach, N.R.
"Capping interactions in isolated a-helices:
position dependent substitution effects and
structure of a serine capped peptide helix"
Biochem. 32, 421 (1993). |
| 78. Geierstanger, B.H., Dwyer,
T.J., Bathini, Y., Lown, J.W. & Wemmer,
D.E. "NMR Characterization of a
Heterocomplex Formed by Distamycin A and its
Analog 2-ImD with
d(CGCAAGTTGGC):d(GCCAACTTGCG). The 1:1:1
Heterocomplex is Favored over either 2:1
Homocomplex" J.Am.Chem.Soc. 115, 4474
(1993). |
| 77. Sastry,
S.S., Spielmann, H.P., Dwyer, T.J., Wemmer,
D.E. & Hearst, J.E. "Recent advances in
the synthesis and structure determination of
site specifically psoralen-modified DNA
oligonucleotides" J.
Photochem.Photobiol. B: Biol., 14, 65-79
(1992). |
| 76. Wemmer, D.E., Wedemayer,
G.J. & Glazer, A.N. "Phycobilins of
Cryptophycean Algae: Novel Linkage of
Dihydrobiliverdin in a Phycoerythrin 555 and
a Phycocyanin 645" J.Biol.Chem.
268, 1658 (1993). |
| 75. Kubinec, M.G. & Wemmer,
D.E. "Solution NMR of Water on Protein
Surfaces" Current Opinion in Structural
Biology, 2, 828 (1992). |
| 74. Kubinec, M.G. & Wemmer,
D.E. "NMR Evidence for DNA Bound Water in
Solution" J.Am.Chem.Soc. 114, 8739-8740
(1992). |
| 73. Ellman, J.A., Volkman, B.,
Mendel, D., Schultz, P.G. & Wemmer, D.E.
"Site-Specific Isotope Labeling of Proteins
for NMR Studies" J.Am.Chem.Soc.
114, 7959-7960 (1992). |
| 72. Mrksich, M., Wade, W.S.,
Dwyer, T.J., Geierstanger, B.H., Wemmer,
D.E. & Dervan, P.B. "Antiparallel
Side-By-Side Dimeric Motif for Sequence
Specific Recognition in the Minor Groove of
DNA by the Designed Peptide
1-Methyl-imidazole-2-carboxamide-netropsin" Proc.Natl.Acad.Sci.
89, 7586 (1992). |
| 71. Storrs, R.W., Truckses, D.
& Wemmer, D.E. "Helix Propagation in
Trifluoroethanol Solutions" Biopolymers 32,
1695 (1992). |
| 70. Lyu, P.C., Zhou, H., Jelveh,
N., Wemmer, D.E. & Kallenbach, N.R.
"Position-Dependent Stabilizing Effects in
a-Helices: N Terminal Capping in Synthetic
Model Peptides" J.Am.Chem.Soc.
114, 6560 (1992). |
| 60. Tomic, M.T., Somoza, J.R.,
Wemmer, D.E., Park, Y.W., Cho, J.M. &
Kim, S.-H. "Secondary Structure and General
Topology of Single-Chain-Monellin in
Solution as Determined by Proton 2D NMR
Spectroscopy" J.Biol.NMR
2, 557 (1992). |
| 68. Gaillard, J., Albrand,
J.-P., Moulis, J.-M. & Wemmer, D.E.
"Sequence-Specific Assignments of the 1H NMR
Spectra of Reduced High Potential Ferredoxin
(HiPIP) from Chromatium vinosm" Biochem. 31,
5632 (1992). |
| 67. Rye, H.S., Yue, S., Wemmer,
D.E., Quesada, M.A. Haugland, R.P., Mathies,
R.A. & Glazer, A.N. "Stable fluorescent
complexes of double-stranded DNA with
bis-intercalating asymmetric cyanine dyes. Properties and
applications" Nucleic
Acids Research, 20, 2803 (1992). |
| 66. Dwyer, T.J., Geierstanger,
B.H., Bathini, Y., Lown, J.W. & Wemmer,
D.E. "Design and Binding of a Distamycin A
Analog to d(CGCAAGTTGGC):d(GCCAACTTGCG):
Synthesis, NMR Structure and Implications
for the Design of Sequence-Specific Minor
Groove Binding Oligopeptides" J.Am.Chem.Soc.
114, 5911 (1992). |
| 65. Wedemayer, G.J., Kidd, D.G.,
Wemmer, D.E. & Glazer, A.N. "Occurrence
of Dihydrobiliverdin and Mesobiliverdin in
Cryptomonad Biliproteins" J.Biol.Chem. 267,
7315 (1992). |
| 64. Werner, M.H. & Wemmer
D.E. "Identification of a Protein Binding
Surface by Differential Amide Proton
Exchange Measurements: Application to
Bowman-Birk Serine Protease Inhibitor"
J.Mol. Biol. 225, 873 (1992). |
| 63. Amaratunga, M.,
Snowden-Ifft, E.A., Wemmer, D.E. &
Benight, A.S. "Studies of DNA Dumbbells II:
Construction and Characterization of DNA
Dumbbells with a Sixteen Base-Pair Duplex
Stem and Tn End-Loops (n=2,3,4,6,8,10,14)"
Biopolymers 32, 865 (1992). |
| 62. Fagan, P. & Wemmer, D.E.
"Cooperative Binding of Distamycin-A to DNA
in the 2:1 Mode" J.Am.Chem.Soc.
114, 1080 (1992). |
| 61. Werner, M.H. & Wemmer,
D.E. "The Three-Dimensional Structure of
Soybean Trypsin/Chymotrypsin Bowman-Birk
Inhibitor in Solution" Biochem. 31, 999
(1992). |
| 60. Wemmer, D.E. "The
applicability of NMR methods to solution
structure of nucleic acids" Current Opinion
in Structural Biology 1, 452 (1991). |
| 59. Kallick, D.A. and Wemmer,
D.E. "1H NMR of 5'CGCGTATATACGCG 3', A
Duplex and a Four-Membered Loop" Nucleic
Acids Research 19, 6041 (1991). |
| 58. McIntire, W.S., Wemmer,
D.E., Chistoserdov, A., Lidstrom, M.E. "A
New Cofactor in Prokaryotic Enzymes:
Tryptophan Tryptophylquinone as the Redox
Cofactor in Methylamine Dehydrogenase" Science 252, 817
(1991). |
| 57. Wedemayer, G.J., Wemmer,
D.E. and Glazer, A.N. "Phycobilins of
Cryptophycean Algae: Structures of Novel
Bilins with Acryloyl Substituents from
Phycoerythrin 566", J.Biol.Chem. 266, 4731
(1991). |
| 56. Werner, M.H. and Wemmer,
D.E. "1H-Assignments and Secondary Structure
Determination of the Soybean
Trypsin/Chymotrypsin Bowman-Birk Inhibitor" Biochemistry 30,
3356 (1991). |
| 55. Gehring, K., Williams, P.G.,
Pelton, J.G., Morimoto, H, Nikaido, H. and
Wemmer, D.E. "Tritium NMR spectroscopy of
ligand binding to maltose-binding protein"
Biochemistry 30, 5524 (1991). |
| 54. Janes, S.M., Mu, D., Wemmer,
D.E., Smith, A.J., Kaur, S., Maltby, D.,
Burlingame, A.L. & Klinman, J.P., "A New
Redox Cofactor in Eukaryotic Enzymes:
Identification of 6-Hydroxydopa at the
Active Site of Bovine Serum Amine Oxidase"
Science 248, 981 (1990). |
| 53. Pelton, J.G. and Wemmer,
D.E. "Structure and Dynamics of Distamycin A
with d(CGCAAATTGGC): d(GCCAATTTGCG) at Low
Drug:DNA Ratios" J.Biomolec.Stereodyn.
8, 81 (1990). |
| 52. Pease, J.H.B., Storrs, R.W.
and Wemmer, D.E. "Folding and Activity of
Hybrid Sequence, Disulfide Stabilized
Peptides" Proc.Natl.Acad.Sci. 87, 5643
(1990). |
| 51. Pease, A.C. and Wemmer, D.E.
"Characterization of the Secondary Structure
and Melting of a Self-Cleaved RNA Hammerhead
Domain by 1H NMR Spectroscopy"
Biochem. 29, 9039 (1990). |
| 50. Snowden-Ifft, E.A. and
Wemmer, D.E. "Characterization of the
Structure and Melting of DNAs Containing
Backbone Nicks and Gaps" Biochem. 29, 6017
(1990). |
| 49. Pelton, J.G. and Wemmer,
D.E. "Binding Modes and Structure of
Complexes of CGCAAATTTGCG with Distamycin-A"
J.Am.Chem.Soc. 112. 1393 (1990). |
| 48. Pelton,
J.G. and Wemmer, D.E. "Structural
Characterization of a 2:1 Distamycin A -
d(CGCAAATTGGC) Complex by Two-Dimensional
NMR" Proc.
Natl. Acad. Sci. 86, 5723 (1989). |
| 47. Pease, J.H.B., Kumar, N.V.,
Schweitz, H. and Wemmer, D.E. "NMR Studies
of Toxin III from the Sea Anemone Radianthus
paumotensis and Comparison of Its Secondary
Structure with Related Toxins"
Biochem. 28, 2199 (1989). |
| 46. Kintanar, A, Huang, W.-C.,
Schindele, D.C., Wemmer, D.E. and Drobny, G.
"Dynamics of Bases in Hydrated
d[(CGCGAATTCGCG)2]", Biochem. 28, 282
(1989). |
| 45. Pease, J.H.B. and Wemmer,
D.E. "Solution Structure of Apamin by NMR
and Distance Geometry"
Biochem. 27, 8419 (1988). |
| 44. Kumar, N.V., Pease, J.H.B.,
Schweitz, H. and Wemmer, D.E. "Solution
Structure of Sea Anemone Toxins by NMR", in
Marine Toxins: Origin, Structure and
Molecular Pharmacology, Eds. S. Hall &
G. Strichartz, A.C.S. Symposium Series 418,
290-303 (1990). |
| 43. Kleanthous, C., Wemmer, D.E.
and Schachman, H. "The Role of an Active
Site Histidine in the Catalytic Mechanism of
Aspartate Transcarbamylase"
J.Biol.Chem. 263, 13062 (1988). |
| 42. Kintanar, A., Alam, T.M.,
W.-C. Huang, Schindele, D.C., Wemmer, D.E.
& Drobny, G., "Solid State 2H NMR
Investigation of Internal Motion in
2'-Deoxythymidine" J.
Amer. Chem. Soc. 110, 6367 (1988). |
| 41. Williams, P.G., Morimoto, H.
& Wemmer, D.E., "Application of Modern
3H NMR Techniques to Analysis of Complex
Isotopic Products from Hydrogenations" J. Amer. Chem.
Soc. 110, 8038 (1988). |
| 40. Pelton, J.G. and Wemmer,
D.E. "Structural Modelling of the
Distamycin-A d(CGCGAATTCGCG)2 Complex Using
2D NMR and Molecular Mechanics" Biochem. 27, 8088
(1988). |
| 39. Wittebort, R.J., Usha, M.G.,
Ruben, D.J., Wemmer, D.E. and Pines, A.
"Observation of Molecular Reorientation in
Ice by Proton and Deuterium Magnetic
Resonance" J. Amer. Chem. Soc. 110, 5668
(1988). |
| 38. Kumar, N.V., Wemmer, D.E.
and Kallenbach, N.R. "Structure
of P401 (Mast Cell Degranulating Peptide) in
Solution" Biophys.
Chem. 31, 113 (1988). |
| 37. Benight, A.S., Schurr, J.M.,
Flynn, P.F., Reid, B.R. and Wemmer, D.E. "Melting of a
Self-complementary DNA Minicircle" J. Mol.
Biol. 200, 377 (1988). |
| 36. Tomic, M.T., Wemmer, D.E.
and Kim, S.-H. "Structure of a Psoralen
Cross-linked DNA in Solution Determined by
Two-dimensional NMR" Science
238, 1722 (1987). |
| 35. Srivenugopal, K.S., Wemmer,
D.E. and Morris, D.R., "Aggregation of DNA
by analogs of spermidine; enzymatic and
structural studies" Nuc. Acids Res. 15, 2563
(1987). |
| 34. Wemmer, D.E., Kumar, N.V.,
Metrione, R.M., Lazdunski, M., Drobny, G.
and Kallenbach, N.R. "NMR
Analysis and Sequence of Toxin II from the
Sea Anemone Radianthus paumotensis"
Biochemistry 25, 6842 (1986). |
| 33. Klevit, R.E., Wemmer, D.E.
and Reid, B.R. "1H
NMR Studies on the Interaction Between
Distamycin A and a Symmetrical DNA
Dodecamer" Biochemistry
25, 3296 (1986). |
| 32. Wemmer, D.E. and Benight,
A.S. "Preparation and Melting of Single
Strand Circular DNA Loops" Nuc. Acids Res.
13, 8611 (1985). |
| 31. Klevit, R.E., Blumenthal,
D.R., Wemmer, D.E. and Krebs, E.G.
"Interaction of Calmodulin and a
Calmodulin-Binding Peptide From Myosin Light
Chain Kinase: Major Structural Changes in
Both Occur as the Result of Complex
Formation" Biochemistry
24, 8152 (1985). |
| 30. Wemmer, D.E., Wand, A.J.,
Seeman, N.C. and Kallenabach, N.R. "NMR
Analysis of DNA Junctions: Imino Proton NMR
Studies of Individual Arms and Intact
Junction" Biochemistry
24, 5745 (1985). |
| 29. Weber, P.L., Wemmer, D.E.
and Reid, B.R. "1H NMR Studies of Lambda Cro
Repressor 2.
Sequential Resonance Assignments of the 1H
NMR Spectrum" Biochemistry
24, 4553 (1985). |
| 28. Wemmer, D.E., Srivenugopal,
K.S., Reid, B.R. and Morris, D.R. "Studies
on Polyamine Binding to a Defined DNA
Sequence by Nuclear Magnetic Resonance
Spectroscopy" J.
Mol. Biol. 185, 457 (1985). |
| 27. Hare, D.R., Ribeiro, N.S.,
Wemmer, D.E. and Reid, B.R.
"Complete Assignments of the Imino
Protons of E. coli Valine Transfer RNA:
Two-Dimensional NMR Studies in Water" Biochemistry 24,
4300 (1985). |
| 26. Wemmer, D.E., Chou, S.-H.,
Hare, D.R. and Reid, B.R. "Duplex-Hairpin
Transitions in DNA: NMR Studies on
CGCGTATACGCG" Nuc.
Acids. Res. 13, 3755 (1985). |
| 25. Langowski, J., Fujimoto,
B.S., Wemmer, D.E., Benight, A.S., Drobny,
G., Shibata, J.H. and Schurr, J.M. "Deformational
Dynamics and NMR Relaxation of Supercoiled
DNA" Biopolymers
24, 1023 (1985). |
| 24. Wemmer, D.E., Chou, S.-H.
and Reid, B.R. "Sequence Specific
Recognition of DNA. NMR
Assignments and Structural Comparison of
Wild-type and Mutant Lambda OR3 DNA" J. Mol. Biol. 180,
41 (1984). |
| 23. Wemmer, D.E., Chou, S.-H.,
Hare, D.R. and Reid, B.R.
"Sequence Specific Recognition of
DNA. Assignment
of Nonexchangable Proton Resonances in the
Consensus Pribnow Promoter DNA Sequence by
Two-dimensional NMR" Biochemistry 23, 2262
(1984). |
| 22. Chou, S.-H., Wemmer, D.E.,
Hare, D.R. and Reid, B.R. "Sequence Specific
Recognition of DNA. Synthesis
and NMR Studies of the Imino Protons of an
RNA Polymerase Promoter"
Biochemistry 23, 2257 (1984). |
| 21. Roberts, J.K.M., Wemmer, D.
and Jardetzky, O. "Measurement of
Mitochondrial ATPase Activity in Maize Root
Tips by Saturation Transfer 31P Nuclear
Magnetic Resonance" Plant
Physiology 74, 632 (1984). |
| 20. Roberts, J.K.M., Callis, J.,
Wemmer, D., Walbot, V. and Jardetzky, O. "The Mechanism of
Cytoplasmic pH Regulation in Hypoxic Maize
Root Tips and its Role in Survival Under
Hypoxia" Proc.
Natl. Acad. Sci. USA 81, 3379 (1984). |
| 19. Hare, D.R., Wemmer, D.E.,
Chou, S.-H., Drobny, G. and Reid, B.R.
"Assignment of the Nonexchangable Proton
Resonances of d(CGCGAATTCGCG) Using
Two-dimensional NMR Methods"
J. Mol. Biol. 171, 319 (1983). |
| 18. Chou, S.-H., Hare, D.R.,
Wemmer, D.E. and Reid, B.R.
"Sequence-Specific Recognition of
Deoxyribonucleic Acid.
Chemical Synthesis and Nuclear
Magnetic Resonance Assignment of the Imino
Protons of Lambda Phage OR3 Operator
Deoxyribonucleic Acid" Biochemistry 22, 3037
(1983). |
| 17. Mai, M.T., Wemmer, D.E. and
Jardetzky, O. "Effects
of Hydration on the Dynamics of DNA" J. Am. Chem. Soc.
105, 7149 (1983). |
| 16. Wemmer, D. and Kallenbach,
N.R. "The Structure of the Bee Venom Peptide
Apamin Studied by Two-dimensional NMR" Biochemistry 22,
1901 (1983). |
| 15. Wemmer, D., Petrouleas, V.,
Panagiotopoulos, N., Filippakis, S.E. and
Lemmon, R.M. "High
Resolution Solid State NMR and X-ray
Structure Study of Choline Chloride, Bromide
and Iodide" J. Phys. Chem. 87, 999 (1983). |
| 14. Roberts, J.K.M., Wemmer, D.,
Ray, P. and Jardetzky, O. "Regulation of
Cytoplasmic and Vacuolar pH in Maize Root
Tips Under Different Experimental
Conditions" Plant
Physiology 69, 1344 (1982). |
| 13. Gonzales-Mendez, R., Wemmer,
D., Hahn, G., Wade-Jardetzky, N.G. and
Jardetzky, O. "Continuous
Flow NMR Culture System for Mammalian Cells" Biochim. Biophys.
Acta 720, 274 (1982). |
| 12. Wemmer, D., Wade-Jardetzky,
N.G. Robin, E. and Jardetzky, O. "Changes in
the Phosphorous Metabolism of a Diving
Turtle Observed by 31P NMR"
Biochim. Biophys. Acta 720, 281
(1982). |
| 11. Wemmer, D.E., Whitehurst,
D.D. and Pines, A. 13C NMR Studies of Coal
and Coal Extracts" Phil.
Trans. R. Soc. (London) A300, 15 (1981). |
| 10. Ribeiro, A.A., Wemmer, D.,
Bray, R.P. and Jardetzky, O. "A Folded
Structure for the lac-repressor Headpiece" Biochem. Biophys.
Res. Comm. 99, 668 (1981). |
| 9. Hogan, M., Wemmer, D., Bray,
R.P., Wade-Jardetzky, N.G. and Jardetzky, O.
"On the Interaction of the lac-repressor
Headpiece with Nucleic Acids"
FEBS Letters 124, 202 (1981). |
| 8. Wemmer, D., Shvo, H, Ribeiro,
A.A., Bray, R.P. and Jardetzky, O., "High Resolution
Proton Nuclear Magnetic Resonance Studies of
the Exchangeable Resonances of the
lac-repressor Headpiece"
Biochemistry 20, 3351 (1981). |
| 7. Ribeiro, A.A., Wemmer, D.,
Bray, R.P. and Jardetzky, O., "pH Dependence
of the High Resolution Proton Nuclear
Magnetic Resonance Spectrum of the
lac-repressor Headpiece"
Biochemistry 20, 3346 (1981). |
| 6. Ribeiro, A.A., Wemmer, D.,
Bray, R.P., Wade-Jardetzky, N.G. and
Jardetzky, O., "High
Resolution NMR Studies of the
lac-repressor:III Unfolding of the
lac-repressor Headpiece"
Biochemistry 20, 829 (1981). |
| 5. Ribeiro, A.A., Wemmer, D.,
Bray, R.P., Wade-Jardetzky, N.G. and
Jardetzky, O.,"High Resolution NMR Studies
of the lac-repressor:II Partial Analysis of
the Aliphatic Region of the lac-repressor
Headpiece Spectrum" Biochemistry
20, 823 (1981). |
| 4. Ribeiro, A.A., Wemmer, D.,
Bray, R.P., Wade-Jardetzky, N.G. and
Jardetzky, O.,"High Resolution NMR Studies
of the lac-repressor:I Assignments of
Tyrosine Resonances in the N-terminal
Headpiece" Biochemistry 20, 818 (1981). |
| 3. Wemmer, D.E., Ruben, D.J. and
Pines, A., "NMR Study of Molecular
Reorientation under Fivefold Symmetry -
Solid Permethylferrocene"
J. Am. Chem. Soc. 103, 28 (1981). |
| 2. Wemmer, D.E. and Pines, A.,
"Carbon-13 Chemical Shifts in Solid Metal
Sandwich Compounds" J.
Am. Chem. Soc. 103, 34 (1981). |
| 1. Wemmer, D.E., Wolff, E.K. and
Mehring, M., "Multiple Frequency Excitation
(MFE), a Technique for Observing Broadline
Transients" J. Mag. Reson. 42, 460 (1981). |
