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2008
Schroeder L, Meldrum T, Smith M, Lowery TJ, Wemmer DE, Pines A.
Temperature response of 129Xe depolarization transfer and its application
for ultrasensitive NMR detection. Phys Rev Lett. Jun
27;100(25):257603.
2008.
Schroeder L, Chavez L, Meldrum T, Smith M, Lowery TJ, Wemmer DE, Pines A.
Temperature-Controlled Molecular Depolarization Gates in Nuclear Magnetic
Resonance. Angew Chem Int Ed. 2008;47(23):4316-20.
2008.
Fawzi NL, Phillips AH, Ruscio JZ, Doucleff M, Wemmer DE, Head-Gordon T. Structure and dynamics of the Abeta(21-30) peptide from the interplay of NMR experiments and molecular simulations. J Am Chem Soc. 2008 May 14;130(19):6145-58.
2008.
2007 Lowery TJ, Pelton JG, Chandonia JM, Kim R,
Yokota H, Wemmer DE. NMR structure of the N-terminal domain of the
replication initiator protein DnaA.
J Struct Funct Genomics. 2007.
Doucleff M, Pelton JG, Lee PS, Nixon BT, Wemmer
DE. Structural basis of DNA recognition by the alternative
sigma-factor, sigma54.
J Mol Biol. 2007 Jun 15;369(4):1070-8. Tang
YJ, Hwang JS, Wemmer DE, Keasling JD. Shewanella oneidensis MR-1
fluxome under various oxygen conditions.
Appl Environ Microbiol. 2007
Feb;73(3):718-29.
Chen B, Doucleff
M, Wemmer DE, De Carlo S, Huang HH, Nogales E, Hoover TR,
Kondrashkina E, Guo L, Nixon BT. ATP ground- and transition states
of bacterial enhancer binding AAA+ ATPases support complex formation
with their target protein, sigma54. Garcia S, Chavez
L, Lowery TJ, Han SI, Wemmer DE, Pines A. Sensitivity enhancement by
exchange mediated magnetization transfer of the xenon biosensor
signal.
J Magn Reson. 2007 Jan;184(1):72-7. 2006 Cave JW, Werner K, Wemmer DE "Backbone
dynamics of sequence specific recognition and binding by the yeast
Pho4 bHLH domain probed by NMR" Protein. Sci. 9,
2354-2365 (2000).
Rogers JP, Luginbuhl P, Pemberton K, et al.
"Structure-activity relationships in a peptidic alpha 7
nicotinic acetylcholine receptor antagonist" J. Mol. Bio.
304, 911-926 (2000).
Liu K, Cho HS, Hoyt DW, et al.
"Deuterium-proton exchange on the native wild-type transthyretin
tetramer identifies the stable core of the individual subunits and
indicates mobility at the subunit interface" J. Mol. Bio.
303, 555-565 (2000).
Liu K, Cho HS, Lashuel HA, et al.
"A glimpse of a possible amyloidogenic intermediate of
transthyretin" Nat. Struct. Biol.7, 754-757
(2000).
Hawkins, C.A., de Clairac, R.P., Dominey,
R.N., Baird, E.E., White, S., Dervan, P.B. & Wemmer, D.E.
"Structural Basis for Controlling Polyamide Binding Orientation
in the Minor Groove of DNA" J.Am.Chem.Soc.122,
5235-5243 (2000).
Bolvig, S., Hansen, P.E., Morimoto, H.M.,
Wemmer, D.E. & Williams, P.G. "Primary Tritium and Deuterium
Isotope Effects on Chemical Shifts of Compounds Having an
Intramolecular Hydrogen Bond" Magn. Res. Chem. 38,
525-535 (2000).
Rubin, S.M., Spence, M.M., Goodson, B.M.,
Wemmer, D.E. and Pines, A. "Evidence of Nonspecific Surface
Interactions Between Laser-Polarized Xenon and Myoglobin in Solution"
Proc.Natl.Acad.Sci. 97, 9472-5 (2000).
Keating KA; Myers JD; Pelton JG; Bair RA;
Wemmer DE; Ellis PD. "Development and use of a virtual NMR
facility." J. Mag. Reson.,143 172-83 (2000).
Cho HS; Lee SY; Yan D; Pan X; Parkinson JS;
Kustu S; Wemmer DE; Pelton JG. "NMR structure of activated
CheY". J. Mol. Biol. 297 543-51 (2000).
Robertson SA; Harada K; Frankel AD; Wemmer
DE. "Structure determination and binding kinetics of a DNA
aptamer-argininamide complex." Biochemistry 39
946-54(2000).
Yan D; Cho HS; Hastings CA; Igo MM; Lee SY;
Pelton JG; Stewart V; Wemmer DE; Kustu S."Beryllofluoride mimics
phosphorylation of NtrC and other bacterial response regulators."
Proc. Natl. Acad. of Sci. USA 96 14789-94 (1999).
>Kern D; Volkman BF; Luginbuhl P; Nohaile
MJ; Kustu S; Wemmer DE. "Structure of a transiently
phosphorylated switch in bacterial signal transduction." Nature
402 894-8 (1999).
Pelton JG; Kustu S; Wemmer DE. "Solution
structure of the DNA-binding domain of NtrC with three alanine
substitutions." J. Mol. Biol.292 1095-110 (1999).
Cho CY; Liu CW; Wemmer DE; Schultz PG.
"Cyclic and linear oligocarbamate ligands for human thrombin."
Bioorganic and Medicinal Chemistry7 1171-9 (1999).
de Clairac, R.P.L.; Seel, C.J.;
Geierstanger, B.H.; Mrksich, M.; Baird, E.E.; Dervan, P.B.; Wemmer,
D.E. "NMR characterization of the aliphatic beta/beta pairing
for recognition of a A center dot T/T center dot A base pairs in the
minor groove of DNA" J. Am. Chem. Soc. 121,
2956-2964 (1999).
Rogers, J.P.; Luginbuhl, P.; Shen, G.S.;
McCabe, R.T.; Stevens, R.C.; Wemmer, D.E. "NMR solution
structure of alpha-conotoxin ImI and comparison to other conotoxins
specific for neuronal nicotinic acetylcholine receptors"
Biochemistry38, 3874-3882 (1999).
Peteranderl, R.; Rabenstein, M.; Shin, Y.K.;
Liu, C.W.; Wemmer, D.E.; King, D.S.; Nelson, H.C.M. "Biochemical
and biophysical characterization of the trimerization domain from the
heat shock transcription factor" Biochemistry38,
3559-3569 (1999).
Driggers, E.M., Liu, C.W., Wemmer, D.E.,
Schultz, P.G. "Structure of the Michaelis Complex of an
Efficient Antibody Acyl Transferase Determined by Transferred Nuclear
Overhauser Enhancement Spectroscopy" J. Am. Chem. Soc.
120, 7395-7396 (1998).
Driggers, E.M., Cho, H.S., Liu, C.W.,
Katzka, C.P., Braisted, A.C., Ulrich, H.D., Wemmer, D.E., Schultz,
P.G. "Mechanistic Studies of an Antibody-Catalyzed Pericyclic
Rearrangement" J. Am. Chem. Soc. 120, 1945-1958
(1998).
Volkman, B.F., Wemmer, D.E. "Deletion
of a Single Amino Acid Changes the Folding of an Apamin Hybrid
Sequence Peptide to that of Endothelin" Biopolymers41,
451-460 (1997).
Heller, J., Laws, D.D., Tomaselli, M., King,
D.S., Wemmer, D.E., A. Pines, Havlin, R.H., Oldfield, E.
"Determination of dihedral angles in peptides through
experimental and theoretical studies of alpha carbon chemical
shielding tensors" J. Am. Chem. Soc. 119,
7827-7831 (1997).
Lee, A.L., Volkman, B.F., Robertson, S.A.,
Rudner. D.Z., Barbash, D.A., Cline, T.W., Kanaar, R., Rio, D.C.,
Wemmer, D.E. "Chemical Shift Mapping of the RNA-Binding
Interface of the Multiple-RBD Protein Sex-Lethal"
Biochem.36,14306-14317 (1997).
Nohaile, M.J., Kern, D., Wemmer, D.E.,
Stedman, K., Kustu, S. "Structural and functional analyses of
activating amino acid substitutions in the receiver domain of NtrC:
Evidence for an activating surface" J. Molec. Biol.273,
299-316 (1997).
Peláez Lamamie de Clairac, R.,
Geierstanger, B.H., Mrksich, M., Dervan, P.B., Wemmer, D.E. "NMR
Characterization of Hairpin Polyamide Complexes with the Minor Groove
of DNA" J. Am. Chem Soc. 119, 7909-7916 (1997).
Geierstanger, B.H., Mrksich, M., Dervan,
P.B., Wemmer, D.E., "Extending the Recognition Site of Designed
Minor Groove Binding Molecules" Nature Structural Biology
3, 321-324 (1996).
Fagan, P.A., Spielmann, H.P., Sigurdsson,
S.T., Rink, S.M., Hopkins, P.B., Wemmer, D.E., "An NMR Study of
[d(CGCGAATTCGCG)]2 containing an Interstrand Cross-Link Derived from
a Distamycin-Pyrrole Conjugate" Nuc. Acids Res.24,
1566-1673 (1996).
Fagan, P.A., Fabrega, C., Eritja, R.,
Goodman, M.F., Wemmer, D.E., "An NMR Study of the Conformation
of the 2-Aminopurine:Cytosine Mismatch in DNA" Biochem.
35, 4026-4033 (1996).
Cho, H.S., Liu, C.W., Damberger, F.F.,
Pelton, J.G., Nelson, H.C.M., Wemmer, D.E. "Yeast Heat Shock
Transcription Factor N-terminal Activation Domains are Unstructured
as Probed by Heteronuclear NMR Spectroscopy" Protein Science
5, 262 (1996).
Damberger, F.F., Pelton, J.G., Liu, C., Cho,
H., Harrison, C.J., Nelson, H.C.M., Wemmer, D.E. "Refined
Solution Structure and Dynamics of the DNA-binding Domain of the Heat
Shock Factor from Kluyveromyces lactis" J. Molec.
Biol. 254, 704 (1995).
Kanaar, R., Lee, A.L., Rudner, D.Z., Wemmer,
D.E., Rio, D.C. "Interaction of the Sex-lethal RNA binding
domains with RNA" EMBO J. 14, 4530 (1995). Spielmann, H.P., Wemmer, D.E., and Jacobsen,
J.P. "The Solution Structure of a DNA Complex with the
Fluorescent bis-intercalator TOTO determined by NMR Spectroscopy"
Biochem. 34, 8542 (1995).
Spielmann, H.P., Fagan, P.A., Bregant, T.M.,
Little, R.D., and Wemmer, D.E., "The Binding Modes of a
Rationally Designed Photoactivated DNA Nuclease Determined by NMR"
Nucl. Acid. Res. 23, 1576 (1995). Spielmann, H.P., Dwyer, T.J., Sastry, S.S.,
Hearst, J.E., Wemmer, D.E., "DNA Structural Reorganization Upon
Conversion of a Psoralen Furanside Monoadduct to an Interstrand
Cross-Link: Implications for DNA Repair" Proc. Natl. Acad.
Sci. USA 92, 2345 (1995).
Volkman, B.F., Nohaile, M.J., Amy, N.K.,
Kustu, S., Wemmer, D.E., "Three- Dimensional Solution Structure
of the N-Terminal Receiver Domain of NTRC" Biochemistry34,
1413 (1995). Lee, A.L., Kanaar, R., Rio, D.C., Wemmer
D.E. "Resonance Assignments and Solution Structure of the Second
RNA-Binding Domain of Sex-Lethal Determined by Multidimensional
Heteronuclear Magnetic Resonance" Biochemistry33,
13775 (1994).
Geierstanger, B.H., Mrksich, M., Dervan,
P.B., Wemmer, D.E., "Design Of A G-C- Specific DNA Minor
Groove-Binding Peptide" Science 266, 646 (1994).
Damberger, F.F., Pelton, J.G., Harrison,
C.J., Nelson, H.C.M, And Others "Solution Structure of the
DNA-Binding Domain of the Heat Shock Transcription Factor Determined
by Multidimensional Heteronuclear Magnetic Resonance Spectroscopy"
Protein Science 3, 1806 (1994).
Lyu, P.C., Wemmer D.E., Zhou, H.X., Pinker,
R.J, Kallenbach, N.R. "Capping Interactions in Isolated Alpha
Helices: Position-Dependent Substitution Effects and Structure of a
Serine-Capped Peptide Helix" Biochemistry32, 421
(1993).
Dwyer, T.J., Geierstanger, B.H., Bathini,
Y., Lown, J.W., Wemmer D.E. "Design and Binding of a Distamycin
A Analog to d(CGCAAGTTGGC):d(GCCAACTTGCG: Synthesis, NMR Structure
and Implications for the Design of Sequence-Specific Minor Groove
Binding Oligopeptides" J. Am. Chem. Soc. 114, 5911
(1992).
Werner, M.H., Wemmer, D.E. "Identification
of a Protein Binding Surface by Differential Amide Proton Exchange
Measurements: Application to Bowman-Birk Serine Protease Inhibitor"
J. Mol. Biol. 225, 873 (1992).
Pease, A.C., Wemmer, D.E. "Characterization
of the Secondary Structure and Melting of a Self-Cleaved Hammerhead
Domain by NMR Spectroscopy" Biochemistry29, 9039
(1990).
Pease, J.H.B., Storrs, R.W., Wemmer, D.E.
"Folding and Activity of Hybrid-Sequence, Disulfide Stabilized
Peptides" Proc. Natl. Acad. Sci. 87, 5643 (1990).
Physical Biosciences Division,
Calvin Laboratory, Lawrence
Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA
94720 ***
Schroder L, Lowery TJ, Hilty
C, Wemmer DE, Pines A. Molecular imaging using a targeted magnetic
resonance hyperpolarized biosensor. Science
2006,
314,
446-449
Pirruccello M, Sondermann H, Pelton JG, Pellicena P,
Hoelz A, Chernoff J, Wemmer DE, Kuriyan J. A dimeric kinase assembly
underlying autophosphorylation in the p21 activated kinases. J.
Mol. Biol. 2006,
361,
312-326
Roberts A, Pelton JG, Wemmer DE. Structural studies of
MJ1529, an O6-methylguanine-DNA methyltransferase. Magn.
Reson. Chem. 2006,
44,
S71-S82
Mynar JL, Lowery TJ, Wemmer DE, Pines A, Frechet JM.
Xenon biosensor amplification via dendrimer-cage supramolecular
constructs. J. Am. Chem. Soc.
2006,
128,
6334-6335
Lowery TJ, Garcia S, Chavez L, Ruiz EJ, Wu T, Brotin
T, Dutasta JP, King DS, Schultz PG, Pines A, Wemmer DE. Optimization
of xenon biosensors for detection of protein interactions.
Chembiochem.
2006,
7,
65-73
2005
Wemmer
DE, Kern D. Beryllofluoride binding mimics phosphorylation of
aspartate in response regulators. J.
Bacteriol. 2005,
187,
8229-8230
Wemmer DE, Kern D. Rebuttal: conformational changes
of Spo0F along the phosphotransfer pathway. J.
Bacteriol. 2005,
187,
8228
Hilty C, Lowery TJ, Wemmer DE, Pines A. Spectrally
Resolved Magnetic Resonance Imaging of a Xenon Biosensor. Angew.
Chem. Int. Ed. Engl. 2005,
45,
70-73
Nixon BT, Yennawar HP, Doucleff M, Pelton JG, Wemmer DE,
Krueger S, Kondrashkina E. SAS Solution Structures of the Apo and
Mg2+/BeF3--Bound
Receiver Domain of DctD from Sinorhizobium meliloti. Biochemistry,
2005,
44,
13962-13969
Doucleff M, Malak LT, Pelton JG, Wemmer DE. The
C-terminal RpoN Domain of σ54 Forms an Unpredicted Helix-Turn-Helix
Motif Similar to Domains of σ70. J.
Biol. Chem. 2005,
280,
41530-41536.
Pelton JG, Shi J, Yokota H, Kim R, Wemmer DE. NMR
structure of hypothetical protein MG354 from Mycoplasma genitalium.
Proteins,
2005,
61,
666-668.
Doucleff M, Chen B, Maris AE, Wemmer DE, Kondrashkina
E, Nixon BT. Negative regulation of AAA + ATPase assembly by two
component receiver domains: a transcription activation mechanism that
is conserved in mesophilic and extremely hyperthermophilic bacteria.
J. Mol. Biol.
2005,
353,
242-255.
Kim HS, Damo SM, Lee SY, Wemmer D, Klinman JP.
Structure and Hydride Transfer Mechanism of a Moderate Thermophilic
Dihydrofolate Reductase from Bacillus stearothermophilus and
Comparison to Its Mesophilic and Hyperthermophilic Homologues.
Biochemistry,
2005,
44,
11428-11439.
Han SI, Garcia S, Lowery TJ, Ruiz EJ, Seeley JA,
Chavez L, King DS, Wemmer DE, Pines A. NMR-based biosensing with
optimized delivery of polarized 129Xe
to solutions. Anal Chem.
2005,
77,
4008-4012.
Choi YJ, Ryu KS, Ko YM, Chae YK, Pelton JG, Wemmer
DE, Choi BS. Biophysical characterization of the interaction domains
and mapping of the contact residues in the XPF-ERCC1 complex. J
Biol Chem. 2005,
280,
28644-28652
Lowery TJ, Doucleff M, Ruiz EJ, Rubin SM, Pines A,
Wemmer DE. Distinguishing multiple chemotaxis Y protein conformations
with laser-polarized 129Xe
NMR Protein Sci.
2005,
14,
848-855.
Rai P, Wemmer DE, Linn S. Preferential binding and
structural distortion by Fe2+
at RGGG-containing DNA sequences correlates with enhanced oxidative
cleavage at such sequences. Nucleic
Acids Res. 2005,
33,
497-510.
Roberts A, Lee SY, McCullagh E, Silversmith RE,
Wemmer DE. Ybiv from Escherichia coli
K12 is a HAD phosphatase. Proteins
2005,
58,
790-801.
2004
Spence
MM, Ruiz EJ, Rubin SM, Lowery TJ, Winssinger N, Schultz PG, Wemmer
DE, Pines A. Development of a functionalized xenon biosensor. J.
Am. Chem. Soc. 2004,
126,
15287-15294.
Lowery TJ, Rubin SM, Ruiz EJ, Pines A, Wemmer DE.
Design of a conformation-sensitive xenon-binding cavity in the
ribose-binding protein. Angew. Chem.
Int. Ed. Engl. 2004,
43,
6320-6322.
Zhang Q, Dwyer TJ, Tsui V, Case DA, Cho J, Dervan
PB, Wemmer DE. NMR structure of a cyclic polyamide-DNA complex. J.
Am. Chem. Soc. 2004,
126,
7958-7966.
Rubin SM, Pelton JG, Yokota H, Kim R, Wemmer DE.
Solution structure of a putative ribosome binding protein from
Mycoplasma pneumoniae
and comparison to a distant homolog. J.
Struct. Funct. Genomics 2003,
4,
235-243.
Shi J, Pelton JG, Cho HS, Wemmer DE. Protein signal
assignments using specific labeling and cell-free synthesis. J.
Biomol. NMR 2004,
28,
235-47.
2003
Lowery
TJ, Rubin SM, Ruiz EJ, Spence MM, Winssinger N, Schultz PG, Pines A,
Wemmer DE. Applications of laser-polarized 129Xe
to biomolecular assays. Mag. Res.
Imaging 2003,
21,
1235-1239.
Wemmer DE. The energetics of structural change in
maltose-binding protein. Proc. Natl.
Acad. Sci. USA 2003,
100,
12529-12530.
Lee SY, De La Torre A, Yan D, Kustu S, Nixon BT,
Wemmer DE. Regulation of the transcriptional activator NtrC1:
structural studies of the regulatory and AAA+ ATPase domains. Genes
Dev 2003,
17,
2552-2563.
Nguyen TN, Wemmer DE. Complete resonance
assignments for the nudix hydrolase DR2356 of Deinococcus
radiodurans. J. Biomol. NMR
2003,
27,
181-182.
Hastings CA, Lee SY, Cho HS, Yan D, Kustu S, Wemmer
DE. High-resolution solution structure of the
beryllofluoride-activated NtrC receiver domain. Biochemistry
2003,
42,
9081-9090.
Gardino AK, Volkman BF, Cho HS, Lee SY, Wemmer DE,
Kern D. The NMR solution structure of BeF3--activated
Spo0F reveals the conformational switch in a phosphorelay system. J.
Mol. Biol. 2003,
331,
245-254.
Shin DH, Roberts A, Jancarik J, Yokota H, Kim R,
Wemmer DE, Kim SH. Crystal structure of a phosphatase with a unique
substrate binding domain from Thermotoga
maritima. Prot.
Sci. 2003,
12,
1464-1472.
2002
Hawkins
CA, Baird EE, Dervan PB, Wemmer DE. Analysis of hairpin polyamide
complexes having DNA binding sites in close proximity. J.
Am. Chem. Soc. 2002,
124,
12689-12696.
Rubin SM, Lee SY, Ruiz EJ, Pines A, Wemmer DE.
Detection and characterization of xenon-binding sites in proteins by
129Xe
NMR spectroscopy. J. Mol. Biol.
2002,
322,
425-440.
Lim KH, Nguyen T, Mazur T, Wemmer DE, Pines A.
Sensitivity enhancement in multiple-quantum NMR experiments with CPMG
detection. J. Mag. Res.
2002,
157,
160-162.
Supekova L, Pezacki JP, Su AI, Loweth CJ, Riedl R,
Geierstanger B, Schultz PG, Wemmer DE. Genomic effects of
polyamide/DNA interactions on mRNA expression. Chem.
Biol. 2002,
9,
821-827.
Liu K, Kelly JW, Wemmer DE. Native state hydrogen
exchange study of suppressor and pathogenic variants of
transthyretin. J. Mol. Biol.
2002,
320,
821-832.
Wang W, Cho HS, Kim R, Jancarik J, Yokota H, Nguyen
HH, Grigoriev IV, Wemmer DE, Kim SH. Structural characterization of
the reaction pathway in phosphoserine phosphatase: crystallographic
"snapshots" of intermediate states. J.
Mol. Biol. 2002,
319,
421-431.
Westler WM, Frey PA, Lin J, Wemmer DE, Morimoto H,
Williams PG, Markley JL. Evidence for a strong hydrogen bond in the
catalytic dyad of transition-state analogue inhibitor complexes of
chymotrypsin from proton-triton NMR isotope shifts. J.
Am. Chem. Soc. 2002,
124,
4196-4197.
2001
Cho
HS, Pelton JG, Yan D, Kustu S, Wemmer DE. Phosphoaspartates in
bacterial signal transduction. Curr.
Opin. Struc. Biol. 2001,
11,
679-684.
Havlin RH, Laws DD, Bitter HM, Sanders LK, Sun H,
Grimley JS, Wemmer DE, Pines A, Oldfield E. An experimental and
theoretical investigation of the chemical shielding tensors of 13Cα
of alanine, valine, and leucine residues in solid peptides and in
proteins in solution. J. Am. Chem.
Soc. 2001,
123,
10362-10369.
Rai P, Cole TD, Wemmer DE, Linn S. Localization
of Fe2+
at an RTGR sequence within a DNA duplex explains preferential
cleavage by Fe2+
and H2O2.
J. Mol. Biol.
2001,
312,
1089-1101.
Laws DD, Bitter HM, Liu K, Ball HL, Kaneko K, Wille
H, Cohen FE, Prusiner SB, Pines A, Wemmer DE. Solid-state NMR studies
of the secondary structure of a mutant prion protein fragment of 55
residues that induces neurodegeneration. Proc.
Natl. Acad. Sci. USA 2001,
98,
11686-11690.
Spence MM, Rubin SM, Dimitrov IE, Ruiz EJ, Wemmer
DE, Pines A, Yao SQ, Tian F, Schultz PG. Functionalized xenon as a
biosensor. Proc. Natl. Acad. Sci. USA
2001,
98,
10654-10657.
Rubin SM, Spence MM, Pines A, Wemmer DE.
Characterization of the effects of nonspecific xenon-protein
interactions on 129Xe
chemical shifts in aqueous solution: further development of xenon as
a biomolecular probe. J. Mag. Res.
2001,
152,
79-86.
Rubin SM, Spence MM, Dimitrov IE, Ruiz EJ, Pines A,
Wemmer DE. Detection of a conformational change in maltose binding
protein by 129Xe
NMR spectroscopy. J. Am. Chem. Soc.
2001,
123,
8616-8617.
Zhang Q, Harada K, Cho HS, Frankel AD, Wemmer DE.
Structural characterization of the complex of the Rev response
element RNA with a selected peptide. Chem.
Biol. 2001,
8,
511-520.
Wemmer DE. Ligands recognizing the minor groove of
DNA: development and applications. Biopolymers
1999-2000,
52,
197-211.
Lee SY, Cho HS, Pelton JG, Yan D, Berry EA, Wemmer
DE. Crystal structure of activated CheY. Comparison with other
activated receiver domains. J. Biol.
Chem. 2001,
276,
16425-16431.
Cave JW, Cho HS, Batchelder AM, Yokota H, Kim R,
Wemmer DE. Solution nuclear magnetic resonance structure of a protein
disulfide oxidoreductase from Methanococcus
jannaschii. Protein
Sci. 2001,
10,
384-96.
Volkman BF, Lipson D, Wemmer DE, Kern D. Two-state
allosteric behavior in a single-domain signaling protein. Science
2001,
291,
2429-2433.
Bastos M, Pease JH, Wemmer DE, Murphy KP, Connelly
PR. Thermodynamics of the helix-coil transition: Binding of S15 and a
hybrid sequence, disulfide stabilized peptide to the S-protein.
Proteins
2001,
42,
523-530.
Hawkins CA, Watson C, Yan Y, Gong B, Wemmer DE.
Structural analysis of the binding modes of minor groove ligands
comprised of disubstituted benzenes. Nuc.
Ac. Res. 2001,
29,
936-942.
Lee SY, Cho HS, Pelton JG, Yan D, Henderson RK, King
DS, Huang L, Kustu S, Berry EA, Wemmer DE. Crystal structure of an
activated response regulator bound to its target. Nat.
Struc. Biol. 2001,
8,
52-56.
Cho H, Wang W, Kim R, Yokota H, Damo S, Kim SH, Wemmer
D, Kustu S, Yan D. BeF3-
acts as a phosphate analog in proteins phosphorylated on aspartate:
structure of a BeF3-
complex with phosphoserine phosphatase. Proc.
Natl. Acad. Sci. USA 2001,
98,
8525-8530.
2000 and earlier
DEWemmer at lbl.gov