Publications
86. "ortho-Quinone Methides from para-Quinones: Total Synthesis of Rubioncolin B."
Lumb, J.P.; Choong, K. C.; Trauner, D. J. Am. Chem. Soc.
2008,
ASAP.
[PDF]
85. "Vinyl Quinones as Diels-Alder Dienes: Concise Synthesis of (-)-Halenaquinone."
Kienzler, M. A.; Suseno, S; Trauner, D. J. Am. Chem. Soc.
2008,
ASAP.
[PDF]
84. "Introduction: Chemical Approaches to Neurobiology" (guest editorial).
Trauner, D. Chem. Rev.
2008,
105, 1499.
[PDF]
83. "Mechanistic Investigations into the Acid-Catalyzed Cyclization of a Vinyl Ortho-Quinone Methide."
Bishop, L.M.; Houk, K.N.; Winkler, M.; Bergman, R.G.; Trauner, D. Chem. Eur. J.
2008,
ASAP.
[PDF]
82. "A Structural Link between Inactivation and Block of a K+ Channel."
Ader, C.; Schneider, R.; Hornig, S.; Velisetty, P.; Wilson; E. M.; Lange, A.; Giller, K.; Ohmert, I.; Martin-Eauclaire, M.-F.; Trauner, D.; Becker, S.; Pongs, O.; Baldus, M. Nature Struct. Mol. Biol.
2008,
15, 605.
[PDF]
81. "The Chemistry of Marine Furanocembranoids, Pseudopteranes, Gersolanes, and Related Natural Products."
Roethle, P. A.; Trauner D. Nat. Prod. Rep.
2008,
25, 298.
[PDF]
80. "Photochemical Control of Endogenous Ion Channels and Cellular Excitability".
Fortin, D.L.; Banghart, M.R., Dunn, T.D.; Borges, K.; Wagnaar, D.A.; Gaudry, Q.; Karakossian, M.; Otis, T.W.; Kristan, W.B.; Trauner, D.: Kramer, R.H. Nature Meth.
2008,
5, 331.
[PDF]
79. "Conjugate Addition of Allyl Stannanes with Concomitant Triflation."
Beaulieu, E. D.; Voss, L.; Trauner, D. Org. Lett.
2008,
10, 869.
[PDF]
78. "Biomimetic Synthesis of the Shimalactones."
Sofiyev, V.; Navarro, G.; Trauner, D. Org. Lett.
2008,
10, 149.
[PDF]
77. "Regulating Enzymatic Activity with a Photoswitchable Affinity Label." Harvey, J.; Trauner, D. Chem. Biochem. 2008, 9, 191. [PDF]
76. "All Optical Interface for Parallel, Remote, and Spatiotemporal Control of Neuronal Activity."
Wang, S.; Szobota, S.; Wang, Y.; Volgraf, M.; Liu, Z.; Sun, C.; Trauner, D.; Isacoff, E. Y.; Zhang, X. Nano Lett.
2007,
7, 3859.
[PDF]
75. "Reversible Photomechanical Switching of Individual Engineered Molecules at a Metallic Surface."
Comstock, M. J.; Levy, N.; Kirakosian, A.;Cho, J.; Lauterwasser, F.; Harvey, J. H.; Strubbe, D. A.;Fréchet, J. M. J.; Trauner, D.; Louie, S. G.; Crommie, M. F. Phys. Rev. Lett.
2007,
99, 038301.
[PDF]
74. "Total Synthesis of (-)-Archazolid B."
Roethle, P. A.; Chen, I. T.; Trauner, D. J. Am. Chem. Soc.
2007,
129, 8960.
[PDF]
73. "Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor."
Gorostiza, P.; Volgraf, M.; Numano,R.; Szobota, S.; Trauner, D.; Isacoff, E. Y.Proc. Natl. Acad. Sci.
2007,
104, 10865.
[PDF]
72. "Total Synthesis of Smenochromene B Through Ring Contraction."
Rosa, C.P.; Kienzler, M.; Olson, B.S.; Liang, G.; Trauner, D. Tetrahedron
2007,
63, 6529.
[PDF]
71. "Remote Control of Neuronal Activity With a Light-Gated Glutamate Receptor."
Szobota, S.; Gorostiza, P.; Del Bene, F.; Wyart, C.; Fortin, D. L.; Kolstad, K. D.; Tulyathan, O.; Volgraf, M.; Numano, R.; Aaron, H. L.; Scott, E. K.; Kramer, R. H.; Flannery, J.; Baier, H.; Trauner, D.; Isacoff, E. Neuron
2007,
54, 535.
[PDF]
70. "Functionalized Azobenzenes Through Cross-Coupling with Organotrifluoroborates"
Harvey, J. H.; Bulter, B. K.; Trauner, D. Tetrahedron Lett.
2007,
48, 1661.
[PDF]
69. "Concise Synthesis of the Bacterial DNA Primase Inhibitor (+)-Sch 642305"
Wilson, E. M.; Trauner, D. Org. Lett.
2007,
9, 1327.
[PDF]
68. "Reversibly Caged Glutamate: A Photochromic Agonist of Ionotropic Glutamate Receptors"
Volgraf, M.; Gorostiza, P.; Szobota,S.; Helix, M. R.; Isacoff, E. Y.; Trauner, D.
J. Am. Chem. Soc.
2007,
129,
260.
[PDF]
67. "Total Synthesis of (-)-Heptemerone B and (-)-Guanacastepene E"
Miller, A. K.; Hughes, C. C.; Kennedy-Smith, J. J.; Gradl, S. N.; Trauner, D.
J. Am. Chem. Soc.
2006,
128,
17057.
[PDF]
66. "Engineering Light-Gated Ion Channels"
Banghart, M. R.; Volgraf, M.; Trauner, D.
Biochemistry
2006,
45,
15129.
[PDF]
65. "Exploring Biosynthetic Relationships among Furanocembranoids: Synthesis of (-)-Bipinnatin J, (+)-Intricarene, (+)-Rubifolide, and (+)-Isoepilophodione B "
Roethle, P. A.; Hernandez, P. T.; Trauner, D.
Org. Lett.
2006,
8,
5901.
[PDF]
64. "Development of a Friedel-Crafts Triflation"
Grundl, M. A.; Kaster, A.; Beaulieu, E. D.; Trauner, D.
Org. Lett.
2006,
8,
5429.
[PDF]
63. "Photochemical Origin of the Immunosuppressive SNF4435C/D and Formation of Orinocin through Polyene Splicing"
Müller, M.; Kusebauch, B.; Liang, G.; Beaudry, C. M.; Trauner, D.; Hertweck, C.
Angew. Chem. Int. Ed.
2006,
46, 7835.
[PDF]
62. "Mapping the Chemistry of Highly Unsaturated Pyrone Polyketides"
Miller, A.K.; Trauner, D.
Synlett.
2006,
14,
2295.
[PDF]
61. "Light-Induced Depolarization of Neurons Using a Modified Shaker K Channel and a Molecular Photoswitch"
Chambers, J. J.; Banghart, M. R.; Trauner, D.; Kramer, R. H.
J. Neurophysiol.
2006,
96
2792.
[PDF]
60. "Synthesis of Taiwaniaquinoids via Nazarov Triflation"
Liang, G.; Xu, Y.; Seiple, I.B.; Trauner, D.
J. Am. Chem. Soc.
2006,
128,
11022.
[PDF]
59. "An Expedient Synthesis of (±)-Bipinnatin J."
Roethle, P. A.; Trauner, D.
Org. Lett.
2006,
8,
345.
[PDF]
58. "Synthetic Studies Toward the Haouamines."
Grundl, M. A.; Trauner, D.
Org. Lett.
2006,
8,
23.
[PDF]
57. "Allosteric Control of an Ionotropic Glutamate Receptor with an Optical Switch."
Volgraf, M.; Gorostiza, P.; Numano, R.; Kramer, R. H.; Isacoff, E.; Trauner, D.
Nature Chem. Bio.
2006,
1,
47.
[PDF]. Featured in "Science": [PDF].
56. "Pericyclic Reactions of Prenylated Naphthoquinones: Biomimetic Synthesis of Mollugin and Microphyllaquinone."
Lumb, J. P.; Trauner, D.
Org. Lett.
2005,
7,
5865.
[PDF]
55. "Photochemical Tools for Remote-Control of Ion Channels in Excitable Cells." Kramer, R. H.; Chambers, J. J.; Trauner, D. Nature Chem. Bio. 2005, 1, 360.
54. "Biosynthetic and Biomimetic Electrocyclizations."
Beaudry, C. M.; Malerich, J. P.; Trauner, D.
Chem. Rev.
2005,
105,
4757.
[PDF]
53. "Concise Synthesis of (±)-Rhazinilam through Direct Coupling."
Bowie, A. L., Jr.; Hughes, C. C.; Trauner, D.
Org. Lett.
2005,
7,
5207.
[PDF]
52. "Photosensitized Conversion of 9,10-Deoxytridachione to Photodeoxytridachione."
Zuidema, D. R.; Miller, A. K.; Trauner, D.; Jones, P. B.
Org. Lett.
2005,
7,
4959.
[PDF]
51. "Total Synthesis of (-)-SNF4435 C and (+)-SNF4435 D."
Beaudry, C. M.; Trauner, D.
Org. Lett.
2005,
7,
4475.
[PDF]
50. "A Glimpse at the Grail."
Trauner, D.
Nature Chem. Bio.
2005,
1,
189.
[PDF]
49. "The Meirwein-Eschenmoser-Claisen Rearrangement."
Gradl, S. N.; Trauner, D.
In Claisen Rearrangements, Hiersemann, M.; Nubbemeyer, U., Eds;
Weinheim: Wiley-VCH 2005, Chapter 7.
[PDF]
48. "Infrared Hole Burning and Conformational Change in a Borane-Ammonia Complex."
Endicott, C. A.; Strauss, H. L.; Hughes, C. C.; Trauner, D.
J. Phys Chem. A
2005,
109,
7714.
[PDF]
47. "An Electrochemical Approach to the Guanacastepenes."
Hughes, C. C.; Miller, A. K.; Trauner, D.
Org. Lett.
2005,
7,
3425.
[PDF]
46. "Mining the Tetraene Manifold: Total Synthesis of Complex Pyrones from Placobranchus ocellatus."
Miller, A. K.; Trauner, D.
Angew. Chem., Int. Ed.
2005,
44,
4602.
[PDF]
45. "Biomimetic Synthesis of Elysiapyrones A and B."
Barbarow, J. E.; Miller, A. K.; Trauner, D.
Org. Lett.
2005,
7,
2901.
[PDF]
44. "Stereoselective Syntheses of the Bioactive Polypropionates Aureothin, N-Acetylaureothamine, and Aureonitrile."
Liang, G.; Seiple, I. B.; Trauner, D.
Org. Lett.
2005,
7,
2837.
[PDF]
43. "Rational Design of a Chiral Palladium(0) Olefin Complex of Unprecedented Stability."
Grundl, M. A.; Kennedy-Smith, J. J.; Trauner, D.
Organometallics
2005,
24,
2831.
[PDF]
42. "Biomimetic Synthesis of Antimalarial Naphthoquinones."
Malerich, J. P.; Maimone, T. J.; Elliott, G. I.; Trauner, D.
J. Am. Chem. Soc.
2005,
127,
6276.
[PDF]. Correction [PDF]
41. "Dienophile Twisting Causes Rate Enhancements in Intramolecular Diels-Alder Cycloadditions: A DFT Study."
Khuong, K. S.; Beaudry, C.; Trauner, D.; Houk, K. N.
J. Am. Chem. Soc.
2005,
127,
3688.
[PDF]
40. "Biomimetic Synthesis and Structure Elucidation of Rubicordifolin, a Cytotoxic Natural Product from Rubia cordifolia."
Lumb, J. P.; Trauner, D.
J. Am. Chem. Soc.
2005,
127,
2870.
[PDF]
39. "Stereoselective Synthesis of the Placidenes and Cyercene A." Liang, G.; Miller, A. K.; Trauner, D.
Org. Lett.
2005,
7,
819.
[PDF]
38. "Concise Synthesis of (±)-Smenochromene D (Likonide B)." Olson, B. S.; Trauner D, Synlett 2005, 700. [PDF]
37. "Biomimetic Synthesis of Natural Products Isolated from Bignoniaceae." Malerich, J. P.; Trauner, D. In Strategies and Tactics in Organic Synthesis; Harmata, M., Ed.; Elsevier: Amsterdam, 2004; Vol. 5. pp 417-436. [PDF]
36. "Light-Activated Ion Channels for Remote Control of Neuronal Firing." Banghart, M. R.; Borges, K.; Isacoff, E. Y.; Trauner, D.; Kramer R. H. Nature Neuroscience 2004, 7, 1381. [PDF]. Featured in "Science": [PDF].
35. "Palladium-Catalyzed Couplings to Nucleophilic Heteroarenes: The Total Synthesis of (-)-Frondosin B." Hughes, C. C.; Trauner, D. Tetrahedron 2004, 60, 9675. [PDF]
34. "Enantioselective Nazarov Reactions through Catalytic Asymmetric Proton Transfer." Liang, G.; Trauner, D. J. Am. Chem. Soc. 2004, 126, 9544. [PDF]
33. "The Total Synthesis of (-)-Crispatene." Miller, A. K.; Byun, D. H.; Beaudry, C. M.; Trauner, D. Proc. Natl. Acad. Sci. 2004, 101, 12019. [PDF]
32. "Metabolic Modulation of Potassium Channels." Trauner, D.; Kramer, R. H. Science STKE 2004, 233, pe20. [PDF]
31. "Efficient Nazarov Cyclizations of 2-Alkoxy-1,4-pentadien-3-ones." Liang, G.; Gradl, S. N.; Trauner, D. Org. Lett. 2003, 5, 4931. [PDF]
30. "Potassium Channels: Symmetric, Selective, Sensitive." Trauner, D. Angew. Chem., Int. Ed. 2003, 42, 5671. [PDF]
29. "Direct Catalytic Asymmetric Amination of Aldehydes: Synthesis of Evans Oxazolidinones and α-Amino Acids." Hughes, C. C.; Trauner, D. Chemtracts 2003, 16, 511. [PDF]
28. "Development of Novel Lewis Acid Catalyzed Cycloisomerizations: Synthesis of Bicyclo[3.1.0]hexenes and Cyclopentenones." Miller, A. K.; Banghart, M. R.; Beaudry, C. M.; Suh, J. M.; Trauner, D. Tetrahedron 2003, 59, 8919. [PDF]
27. "Synthetic Studies toward the Guanacastepenes." Hughes, C. C.; Kennedy-Smith, J. J.; Trauner, D. Org. Lett. 2003, 5, 4113. [PDF]
26. "Protein Surface Recognition by Rational Design: Nanomolar Ligands for Potassium Channels." Gradl, S.; Felix, J. P.; Isacoff, E. Y.; Garcia, M. L.; Trauner, D. J. Am. Chem. Soc. 2003, 125, 12668. [PDF]
25. "Reductive Cyclization of β-Hydroxy Nitriles: A New Synthesis of Glycoxylamines." Dorsey, A. D.; Barbarow, J. E.; Trauner, D. Org. Lett. 2003, 5, 3237. [PDF]
24. "Biomimetic Synthesis of (±)-Pinnatal and (±)-Sterekunthal A." Malerich, J. P.; Trauner, D. J. Am. Chem. Soc. 2003, 125, 9554. [PDF]
23. "Intramolecular Diels-Alder Reactions of 5-Vinyl-1,3-Cyclohexadienes." Ng, S. M.; Beaudry, C. M.; Trauner, D. Org. Lett. 2003, 5, 1701. [PDF]
22. "Total Synthesis of (±)-Photodeoxytridachione through a Lewis Acid Catalyzed Cyclization." Miller, A. K.; Trauner, D. Angew. Chem., Int. Ed. 2003, 42, 549. [PDF]
21. "Enzymatic Desymmetrization of a Centrosymmetric Diacetate." Böhm, C.; Austin, W. F.; Trauner, D. Tetrahedron: Asymmetry 2003, 14, 71. [PDF]
20. "The Total Synthesis of (-)-Amathaspiramide F." Hughes, C. C.; Trauner, D. Angew. Chem., Int. Ed. 2002, 41, 4556. [PDF]
19. "Boron-Ammonia Complexes Stabilized by Hydrogen Bonding." Hughes, C. C.; Scharn, D.; Mulzer, J.; Trauner, D. Org. Lett. 2002, 4, 4109. [PDF]
18. "Synthetic Studies Toward SNF4435 C and SNF4435 D." Beaudry, C. M.; Trauner, D. Org. Lett. 2002, 4, 2221. [PDF]
17. "Concise Total Synthesis of (-)-Frondosin B Using a Novel Palladium Catalyzed Cyclization."
Hughes, C. C.; Trauner, D.
Angew. Chem., Int. Ed.
2002,
41, 1569.
[PDF]. Correction [PDF]
16. "A Practical Variant of the Claisen-Eschenmoser Rearrangement: Synthesis of Unsaturated Morpholine Amides." Gradl, S. N.; Kennedy-Smith, J. J.; Kim, J.; Trauner, D. Synlett 2002, 3, 411. [PDF]
15. "The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study and Applications in Natural Product Synthesis." Chemler, S. R.; Trauner, D.; Danishefsky, S. J. Angew. Chem., Int. Ed. 2001, 40, 4544.
14. "Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid." Carson, M. W.; Kim, G.; Hentemann, M. F.; Trauner, D.; Danishefsky, S. J. Angew. Chem., Int. Ed. 2001, 40, 4450.
13. "On the Conformations of Halichlorine and the Pinnaic Acids: Nitrogen Inversion as a Possible Determinant of Biological Profile." Trauner, D.; Danishefsky, S. J. Helv. Chim. Acta 2000, 83, 2344.
12. "Synthesis of Immunomodulatory Marine Natural Products." Danishefsky, S. J.; Inoue, M.; Trauner, D. in "The Role of Natural Products in Drug Discovery," Ernst Schering Research Foundation (ESRF) Workshop 32, pp. 1-24, Heidelberg, New York: Springer 2000.
11. "Morphine Synthesis and Biosynthesis--an Update." Novak, B. H.; Hudlicky, T.; Reed, J. W.; Mulzer, J.; Trauner, D. Curr. Org. Chem. 2000, 4, 343.
10. "Total Synthesis of (+)-Halichlorine, an Inhibitor of VCAM-1 Expression." Trauner, D.; Schwarz, J. B.; Danishefsky, S. J. Angew. Chem., Int. Ed. 1999, 38, 3542.
9. "Studies Toward the Total Synthesis of Halichlorine: Asymmetric Synthesis of the Spiroqinolizidine Subunit." Trauner, D.; Danishefsky, S. J. Tetrahedron Lett. 1999, 40, 6513.
8. "Insight into the Mechanism of the Saegusa Oxidation: Isolation of a Novel Palladium(0) Tetraolefin Complex." Porth, S.; Bats, J. W.; Trauner, D.; Giester, G.; Mulzer, J. Angew. Chem., Int. Ed. 1999, 38, 2015.
7. "Practical Synthesis of (-)-Morphine." Mulzer, J.; Trauner, D. Chirality 1999, 11, 475.
6. "About the Use of Molecular Workbenches and Platforms in Organic Synthesis." Mulzer, J., Schein, K.; Bohm, I.; Trauner, D. Pure Appl. Chem. 1998, 70, 1487.
5. "Synthesis of Enantiomerically Pure Morphine Alkaloids: The Hydrophenathrene Route." Trauner, D.; Bats, J. W.; Werner, A.; Mulzer, J. J. Org. Chem. 1998, 63, 5908.
4. "New Ventures in the Construction of Complex Heterocycles: Synthesis of Morphine and Hasubanan Alkaloids." Trauner, D.; Porth, S.; Opatz, T.; Bats, J. W.; Giester, G.; Mulzer, J. Synthesis 1998, 653.
3. "The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatropic Rearrangement." Mulzer, J.; Bats, J. W.; List, B.; Opatz, T.; Trauner, D. Synlett 1997, 5, 441.
2. "Formal Total Synthesis of (-)-Morphine by Cuprate Conjugate Addition." Mulzer, J.; Duerner, G.; Trauner, D. Angew. Chem., Int. Ed. 1997, 35, 2830.
1. "Stereoselective Insertion of Ketenes into O,O-Acetals: Synthesis of β-Alkoxy Esters and 1,4-Dioxepanones." Mulzer, J.; Trauner, D.; Bats, J. W. Angew. Chem., Int. Ed. 1996, 35, 1970.