Sarpong Group (Berkeley)
  1. Doering, N. A.; Sarpong, R.; Hoffmann, R. W. "A Case for Bond-Network Analysis in Bridged Polycyclic Complex Molecule Synthesis: Hetidine and Hetisine Diterpenoid Alkaloids" Angew. Chem. Int. Ed. 2019, Accepted.

  2. Hugelshofer, C. H.; Palani, V.; Sarpong, R. "Calyciphylline B-type Alkaloids: Evolution of a Synthetic Strategy to (–)-Daphlongamine H" J. Org. Chem. 2019, 84, 14069–14091.

  3. Nagasawa, S.; Jones, K. E.; Sarpong, R. "Enantiospecific Entry to a Common Decalin Intermediate for the Syntheses of Highly Oxygenated Terpenoids" J. Org. Chem. 2019, 84, 12209–12215.

  4. Palani, V.; Hugelshofer, C. L.; Sarpong, R. "A Unified Strategy for the Enantiospecific Total Synthesis of Delavatine A and Formal Synthesis of Incarviatone A" J. Am. Chem. Soc. 2019, 141, 14421-14432.

  5. Pfaffenbach, M.; Bakanas, I.; O'Connor, N. R.; Herrick, J. K.; Sarpong, R. "Total Syntheses of Xiamycins A, C, F, H and Oridamycin A and Preliminary Evaluation of their Anti-Fungal Properties" Angew. Chem. Int. Ed. 2019, 58, 15304–15308.

  6. Rovira, A. R.; Müller, N.; Deng, W.; Ndubaku, C.; Sarpong, R. "Bio-inspired synthesis of xishacorenes A, B, C, and a new congener from fuscol" Chem. Sci. 2019, 10, 7788–7791. (PMCID 6761873)

  7. Gritsch, P. J.; Giménez-Nueno, I.; Wonilowicz, L.; Sarpong, R. "Copper-catalyzed [4+2] cycloaddition of 9H-cyclohepta[b]pyridine-9-one and electron-rich alkenes" J. Org. Chem. 2019, 84, 8717–8723.

  8. Owens, K. O.; McCowen, S. V.; Blackford, K. A.; Ueno, S.; Hirooka, Y.; Weber, M.; Sarpong, R. "Total Synthesis of the Diterpenoid Alkaloid Arcutinidine Using a Strategy Inspired by Chemical Network Analysis" J. Am. Chem. Soc. 2019, 141, 13713–13717. ChemRxiv.

  9. Norseeda, K.; Gasser, V.; Sarpong, R. "A Late-Stage Functionalization Approach to Derivatives of the Pyrano[3,2-a]carbazole Natural Products" J. Org. Chem. 2019, 84, 5965–5973.

  10. Hugelshofer, C. L.; Palani, V.; Sarpong, R. "The Calyciphylline B-type Alkaloids: Total Syntheses of (–)-Daphlongamine H and (–)-Isodaphlongamine H" J. Am. Chem. Soc. 2019, 141, 8431–8435. ChemRxiv. (PMCID 6750003)

  11. Johnson, R. E.; Ree, H.; Hartmann, M.; Lang, L.; Sawano, S.; Sarpong, R. "Total Synthesis of Pentacyclic (–)-Ambiguine P using Sequential Indole Functionalizations" J. Am. Chem. Soc. 2019, 141, 2233–2237. (PMCID 6742481)

  12. Palani, V.; Hugelshofer, C. L.; Kevlishvili, I.; Liu, P.; Sarpong, R. "A short synthesis of delavatine A unveils new insights into site-selective cross-coupling of 3,5-dibromo-2-pyrone" J. Am. Chem. Soc. 2019, 141, 2652–2660.

  13. Kearney, S. E.; Zahoránszky-Köhalmi, G; Brimacombe, K. R.; Henderson, M. J.; Lynch, C.; Zhao, T.; Wan, K. K.; Itkin, Z.; Dillon, C.; Shen, M., Cheff, D. M.; Lee, T. D.; Bougie, D.; Cheng, K.; Coussens, N. P.; Dorjsuren, D.; Eastman, R. T.; Huang, R.; Iannotti, M. J.; Karavadhi, S.; Klumpp-Thomas, C.; Roth, J. S.; Sakamuru, S.; Sun, W.; Titus, S. A.; Yasgar, A.; Zhang, Y.; Zhao, J.; Andrade, R. B.; Brown, M. K.; Burns, N. Z.; Cha, J. K.; Mevers, E. E.; Clardy, J.; Clement, J. A.; Crooks, P. A.; Cuny, G. D.; Ganor, J.; Moreno, J.; Morrill, L. A.; Picazo, E.; Susick, R. B.; Garg, N. K.; Goess, B. C.; Grossman, R. B.; Hughes, C. C.; Johnston, J. N.; Joullie, M. M.; Kinghorn, A. D.; Kingston, D. G. I.; Krische, M. J.; Kwon, O.; Maimone, T. J.; Murphy, B. T.; Nagorny, P.; Majumdar, S.; Maloney, K. N.; Mohamed, E.; Olson, D. E.; Overman, L. E.; Brown, L. E.; Snyder, J. K.; Porco, J. A., Jr.; Sharma, I.; Shaw, J. T.; Rivas, F.; Ross, S. A.; Sarpong, R.; Xu, Z.; Shen, B.; Shi, W.; Stephenson, C. R. J.; Tang, Y.; Taylor, R. E.; Thomson, R. J.; Wuest, W. M.; Zakarian, A.; Zhang, Y.; Verano, A. L.; Tan, D. S.; Vosburg, D. A.; Wu, J.; Ren, T.; Zuo, Z.; Inglese, J.; Michael, S.; Simeonov, A.; Zheng, W.; Shinn, P.; Jadhav, A.; Boxer, M. B.; Hall, M. D.; Xia, M.; Guha, R.; Rohde, J. M. "Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space" ACS Cent. Sci. 2018, 4, 1727–1741.

  14. Roque, J. B.; Kuroda, Y.; Göttemann, L. T.; Sarpong, R. "Deconstructive diversification of cyclic amines" Nature 2018, 564, 244–248. (PMCID 6317721)

  15. Doering, N. A.; Kou, K. G. M.; Norseeda, K.; Lee, J. C.; Marth, C. J.; Gallego, G. M.; Sarpong R. "A Copper-Mediated Conjugate Addition Approach to Analogs of Aconitine-Type Diterpenoid Alkaloids" J. Org. Chem. 2018, 83, 12911–12920. (PMCID 6214151)

  16. Haines, B. E.; Sarpong, R.; Musaev, D. G. "On the Generality and Strength of Transition Metal β-effects" J. Am. Chem. Soc. 2018, 140, 10612–10618. (Article Correction)

  17. Kerschgens, I.; Rovira, A. R.; Sarpong, R. "Total Synthesis of (–)-Xishacorene B from (R)-Carvone using a C–C Activation Strategy" J. Am. Chem. Soc. 2018, 140, 9810–9813.

    Also highlighted in Nature Reviews Chemistry and Synfacts.

  18. Roque, J. B.; Kuroda, Y.; Göttemann, L. T.; Sarpong, R. "Deconstructive fluorination of cyclic amines by carbon-carbon cleavage" Science 2018, 361, 171–174. (PMCID 6287955)

    Also highlighted on C&EN, ChemistryWorld, Phys.Org, Brinkwire, and Berkeley Chemistry College News.

  19. Blümel, M.; Nagasawa, S.; Blackford, K.; Hare, S. R.; Tantillo, D. J.; Sarpong, R. "Rearrangement of Hydroxylated Pinene Derivatives to Fenchone-Type Frameworks: Computational Evidence for Dynamically-Controlled Selectivity" J. Am. Chem. Soc. 2018, 140, 9291–9298.

    Also featured in the blog Computational Organic Chemistry

  20. Kou, K. G. M.; Pflueger, J. J.; Kiho, T.; Morrill, L. C.; Fisher, E. L.; Clagg, K.; Lebold, T. P.; Kisunzu, J. K.; Sarpong, R. "A Benzyne-Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine)" J. Am. Chem. Soc. 2018, 140, 8105–8109. (PMCID 6342194)

  21. Usui, K.; Haines, B. E.; Musaev, D. G.; Sarpong, R. "Understanding Regiodivergence in a Pd(II)- Mediated Site-Selective C–H Alkynylation" ACS Catal. 2018, 8, 4516–4517.

  22. Hugelshofer, C. L.; Palani, V.; Sarpong, R. "Oxazaborinines from Vinylogous N-Allylic Amides: Reactivities of Underexplored Heterocyclic Building Blocks" Org. Lett. 2018, 20, 2649–2653

  23. Kuroda, Y.; Nicacio, K. J.; da Silva, I. A.; Leger, P. R.; Chang, S.; Gubiani, J. R.; Deflon, V. M.; Nagashima, N.;Rode, A.; Blackford, K.; Ferreira, A. G.; Sette, L. D.; Williams, D. E.; Andersen, R. J.; Jancar, S.; Berlinck, R. G. S.; Sarpong, R. "Isolation, Synthesis, and Bioactivity Studies of Phomactin Terpenoids" Nat. Chem. 2018, 10, 938–945.

  24. Chen, A. Y.; Lu, Q.; Fu, Y.; Sarpong, R.; Stoltz, B. M.; Zhang, H. "Isocanthine Synthesis via Rh(III)-Catalyzed Intramolecular C–H Functionalization" J. Org. Chem. 2018, 83, 330–337.

  25. Mukai, K.; de Sant'Ana, D. P.; Hirooka, Y.; Mercado-Marin, E. V.; Stephens, D. E.; Kou, K. G. M.; Richter, S. C.; Kelley, N.; Sarpong, R. "Bioinspired chemical synthesis of monomeric and dimeric stephacidin A congeners" Nat. Chem. 2018, 10, 38–44. (PMCID 6317722)

  26. de Rond, T.; Stow, P.; Eigl, I.; Johnson, R. E.; Chan, L. J. G.; Goyal, G.; Baidoo, E. E. K.; Hilson, N. J.; Petzold, C. J.; Sarpong, R.; Keasling, J. D. "Oxidative cyclization of prodigiosin by an alkylglycerol monooxygenase-like enzyme" Nat. Chem. Biol. 2017, 13, 1155–1157. (PMCID 5677514)

  27. Kou, K. G. M.; Kulyk, S.; Marth, C. J.; Lee, J. C.; Doering, N. A.; Li, B. X.; Gallego, G. M.; Lebold, T. P.; Sarpong, R. "A Unifying Synthesis Approach to the C18-, C19-, and C20-Diterpenoid Alkaloids" J. Am. Chem. Soc. 2017, 139, 13882–13896. (PMCID 6372304)

  28. Lindsay, V.; Murphy, R.; Sarpong, R. "Effect of protic additives in Cu-catalysed asymmetric Diels-Alder cycloadditions of doubly activated dienophiles: towards the synthesis of magellanine-type Lycopodium alkaloids" Chem. Commun. 2017, 53, 10291–10294. (PMCID 6289252)

  29. Pflueger, J. P.; Morrill, L. C.; deGruyter, J. N.; Perea, M. A.; Sarpong, R. "Magnesiate Addition/Ring Expansion Strategy To Access 6-7-6 Tricyclic Core of Hetisine-Type C20-Diterpenoid Alkaloids" Org. Lett. 2017, 19, 4632–4635. (PMCID 6287954)

  30. Fraley, A. E.; Garcia-Borràs, M.; Tripathi, A.; Khare, D.; Mercado-Marin, E. V.; Tran, H.; Dan, Q.; Webb, G.; Watts, K.; Crews, P.; Sarpong, R.; Williams, R. M.; Smith, J. L.; Houk, K. N.; Sherman, D. H. "Function and structure of MalA/MalA', iterative halogenases for late-stage C-H functionalization of indole alkaloids" J. Am. Chem. Soc. 2017, 139, 12060–12068. (PMCID 5595095)

  31. Finkbeiner, P.; Murai, K.; Röpke, M.; Sarpong, R. "Total Synthesis of Terpenoids Employing a 'Benzannulation of Carvone' Strategy: Synthesis of (–)-Crotogoudin" J. Am. Chem. Soc. 2017, 139, 11349–11352. (PMCID 6309435)

  32. Wilkerson-Hill, S.M.; Yu, D.; Painter, P.P.; Fisher, E.L.; Tantillo, D.J.; Sarpong, R.; Hein, J.E. "On the Mechanism of a No-metal-added Heterocycloisomerization of Alkynylcyclopropylhydrazones: A Synthesis of Cycloheptane-fused Aminopyrroles Facilitated by Copper Salts at Trace Loadings" J. Am. Chem. Soc. 2017, 139, 10569–10577.

  33. Viart, H.M.F.; Bachmann, A.; Kayitare, W.; Sarpong, R. "β-Carboline Amides as Intrinsic Directing Groups for C(sp2)–H Functionalization" J. Am. Chem. Soc. 2017, 139, 1325–1329.

  34. Wilkerson-Hill, S.M.; Sawano, S.; Sarpong, R. "Bis(1-cyanovinylacetate) is a Linear Precursor to 3-Oxidopyrylium Ions" J. Org. Chem. 2016, 81, 11132–11144.

  35. Kou, K.G.M.; Li, B.X.; Lee, J.C.; Gallego, G.M.; Lebold, T.P.; DiPasquale, A.; Sarpong, R. "Syntheses of Denudatine Diterpenoid Alkaloids: Cochlearenine, N-Ethyl-1α-Hydroxy-17-Veratroyldictyzine, and Paniculamine" J. Am. Chem. Soc. 2016, 138, 10830–10833.

  36. Leal, R.A.; Bischof, C.; lee, Y.V.; Sawano, S.; McAtee, C.C.; Latimer, L.N.; Russ, Z.N.; Dueber, J.E.; Yu, J.-Q.; Sarpong, R. "Application of a Pd-Catalyzed C-H Functionalization/Indolization Method to Syntheses of cis-Trikentrin A and Herbindole B" Angew. Chem. Int. Ed. 2016, 55, 11824–11828.

  37. Wilkerson-Hill, S.M.; Lavados, C.M.; Sarpong, R. "The Diels-Alder Reactivity of 2-Vinylindenes: Synthesis of Functionalized Tetrahydrofluorenes" Tetrahedron 2016, 72, 3635–3640.

  38. Marth, C.J.; Gallego, G.M.; Lee, J.C.; Lebold, T.P.; Kulyk, S.; Kou, K.G.M.; Qin, J.; Lilien, R.; Sarpong, R. "Network-Analysis-Guided Synthesis of Weisaconitine D and Liljestrandinine" Nature 2015, 528, 493–498.

    Use the Maximally Bridged Ring Detector: Program (Examples)

  39. Weber, M.; Owens, K.; Masarwa, A.; Sarpong, R. "Construction of Enantiopure Taxoid and Natural Product-like Scaffolds Using a C-C Bond Cleavage/Arylation Reaction" Org. Lett. 2015, 17, 5432–5435.

  40. Johnson, R.E.; de Rond, T.; Lindsay, V.N.G.; Keasling, J.D.; Sarpong, R. "Synthesis of Cycloprodigiosin Identifies the Natural Isolate as a Scalemic Mixture" Org. Lett. 2015, 17, 3474–3477.

  41. Lindsay, V.N.G.; Viart, H.M.F.; Sarpong, R. "Stereodivergent Intramolecular C(sp3)-H Functionalization of Azavinyl Carbenes: Synthesis of Saturated Heterocycles and Fused N-Heterotricycles" J. Am. Chem. Soc. 2015, 137, 8368–8371.

  42. Mercado-Marin, E.V.; Sarpong, R. "Unified Approach to Prenylated Indole Alkaloids: Total Syntheses of (-)-17-Hydroxycitrinalin B, (+)-Stephacidin A, and (+)-Notoamide I" Chem. Sci. 2015, 6, 5048–5052.

  43. Heller, S.T.; Newton, J.N.; Fu, T.; Sarpong, R. "One-Pot Unsymmetrical Ketone Synthesis Employing a Pyrrole-bearing Formal Carbonyl Dication Linchpin Reagent" Angew. Chem. Int. Ed. 2015, 54, 9839–9843.

  44. Masarwa, A.; Weber, M.; Sarpong, R. "Selective C-C and C-H Bond Activation /Cleavage of Pinene Derivatives: Synthesis of Enantiopure Cyclohexenone Scaffolds and Mechanistic Insights" J. Am. Chem. Soc. 2015, 137, 6327–6334.

  45. Beng, T.K.; Takeuchi, H.; Weber, M.; Sarpong, R. "Stereocontrolled Synthesis of Vicinally Functionalized Piperidines by Nucleophilic β-Addition of Alkyllithiums to α-Aryl Substituted Piperidine Enecarbamates" Chem. Commun. 2015, 51, 7653–7656.

  46. Weber, M.; Owens, K.; Sarpong, R. "Atropurpuran - Missing Biosynthetic Link Leading to the Hetidine and Arcutine C20-Diterpenoid Alkaloids or an Oxidative Degradation Product?" Tetrahedron Lett. 2015, 56, 3600–3603.

  47. Leger, P.R.; Murphy, R.A.; Pushkarskaya, E.; Sarpong, R. "Synthetic Efforts toward the Lycopodium Alkaloids Inspires a Hydrogen Iodide Mediated Method for the Hydroamination and Hydroetherification of Olefins" Chem. Eur. J. 2015, 21, 4377–4383.

  48. Schultz, E.E.; Lindsay, V.N.G.; Sarpong, R. "Expedient Synthesis of Fused Azepine Derivatives using a Sequential Rh(II)-Catalyzed Cyclopropanation / 1-Aza-Cope Rearrangement of Dienyltriazoles" Angew. Chem. Int. Ed. 2014, 53, 9904–9908.

  49. Hamlin, A.M.; Lapointe, D.; Owens, K.; Sarpong, R. "Studies on C20-Diterpenoid Alkaloids: Synthesis of the Hetidine Framework and its Application to the Synthesis of Dihydronavirine and the Atisine Skeleton" J. Org. Chem. 2014, 79, 6783–6800.

  50. Mercado-Marin, E.V.; Garcia-Reynaga, P.; Romminger, S.; Pimenta, E.F.; Romney, D.K.; Lodewyk, M.W.; Williams, D.E.; Andersen, R.J.; Miller, S.J.; Tantillo, D.J.; Berlinck, R.G.S.; Sarpong, R. "Total synthesis and isolation of citrinalin and cyclopiamine congeners" Nature 2014, 509, 318–324.

  51. Hamlin, A.M.; Kisunzu, J.K.; Sarpong, R. "Synthetic strategies toward hetidine and hetisine-type diterpenoid alkaloids" Org. Biomol. Chem. 2014, 12, 1846–1860. (Review)

  52. Beng, T.K.; Wilkerson-Hill, S.M.; Sarpong, R. "Direct Access to Functionalized Azepanes by Cross-Coupling with α-Halo Eneformamides" Org. Lett. 2014, 16, 916-919. (Org. Lett. 2014, 16, 3170 Correction)

  53. Murphy, R.A.; Sarpong, R. "Heathcock-Inspired Strategies for the Synthesis of Fawcettimine-Type Lycopodium Alkaloids" Chem. Eur. J. 2014, 20, 42–56. (Review)

  54. Mundal, D.A.; Sarpong, R. "Synthetic Studies toward the Citrinadin A and B Core Architecture" Org. Lett. 2013, 15, 4952–4955.

  55. Kisunzu, J.K.; Sarpong, R. "Hidden Symmetry Enables a 15 Step Total Synthesis of Pactamycin" Angew. Chem. Int. Ed. 2013, 52, 10694–10696. (Highlight)

  56. Heller, S.T.; Kiho, T.; Narayan, A.R.H.; Sarpong, R. "Protic Solvent Mediated Cycloisomerization of Quinoline and Isoquinoline Propargylic Carbinols: Syntheses of (±)-3-Demethoxyerythratidinone and (±)-Cocculidine" Angew. Chem. Int. Ed. 2013, 52, 11129–11133.

  57. Jeffrey, J.L.; Sarpong, R. "Intramolecular C(sp3)-H Amination" Chem. Sci. 2013, 4, 4092–4106. (Review)

  58. Cortez, F. de J.; Lapointe, D.; Hamlin, A.M.; Simmons, E.M.; Sarpong, R. "Synthetic Studies on the Icetexones: Enantioselective Formal Syntheses of Icetexone and epi-Icetexone" Tetrahedron 2013, 69, 5665–5676.

  59. García-Reynaga, P.; Zhao, C.; Sarpong, R.; Casida, J. "New GABA Receptor Target for [3H] Isoxazoline Insecticide" Chem. Res. Tox. 2013, 26, 514–516.

  60. Schultz, E.E.; Sarpong, R. "Application of In Situ Generated Rh-Bound Trimethylene-methane Variants to the Synthesis of 3,4-Fused Pyrroles" J. Am. Chem. Soc. 2013, 135, 4696–4699.

  61. Hamlin, A.M.; Cortez, F. de J.; Lapointe, D.; Sarpong, R. "Ga(III)-Catalyzed Cycloisomerization Approach to the Diterpenoid Alkaloids: Construction of a Core Structure for the Hetidines and Hetisines" Angew. Chem. Int. Ed. 2013, 52, 4854–4857.

  62. Jeffrey, J.L.; Bartlett, E.S.; Sarpong, R. "Intramolecular C(sp3)—N Coupling by Oxidation of Benzylic C,N-Dianions" Angew. Chem. Int. Ed. 2013, 52, 2194–2197.

  63. Newton, J.N.; Fischer, D.F.; Sarpong, R. "Synthetic Studies on Pseudo-Dimeric Lycopodium Alkaloids: Total Synthesis of Complanadine B" Angew. Chem. Int. Ed. 2013, 52, 1726–1730.

  64. Lebold, T.P.; Wood, J.L.; Deitch, J.; Lodewyk, M.W.; Tantillo, D.J.; Sarpong, R. "A divergent approach to the synthesis of the yohimbinoid alkaloids venenatine and alstovenine" Nat. Chem. 2013, 5, 126–131.

  65. Jeffrey, J.L.; Sarpong, R. "Chichibabin-Type Direct Alkylation of Pyridyl Alcohols with Alkyl Lithium Reagents" Org. Lett. 2012, 14, 5400–5403.

  66. Leal, R.A.; Beaudry, D.R.; Alzghari, S.K.; Sarpong, R. "Synthesis of the Pentacyclic Skeleton of the Indole Alkaloid Arboflorine" Org. Lett. 2012, 14, 5350–5353.

  67. Isaacs, A. K.; Qi, S.; Sarpong, R.; Casida, J. E. "Insect Ryanodine Receptor: Distinct but Coupled Insecticide Binding Sites for [N-C3H3]Chlorantraniliprole, Flubendiamide, and [3H]Ryanodine" Chem. Res. Toxicol. 2012, 25, 1571–1573.

  68. Heller, S. T.; Schultz, E. E.; Sarpong, R. "Chemoselective N-Acylation of Indoles and Oxazolidinones with Carbonylazoles" Angew. Chem. Int. Ed. 2012, 51, 8304–8308.

  69. Fisher, E. L.; Wilkerson-Hill, S. M.; Sarpong, R. "Tungsten-Catalyzed Heterocycloisomerization Approach to 4,5-Dihydro-benzo[b]furans and -indoles" J. Am. Chem. Soc. 2012, 134, 9946–9949.

  70. Lebold, T. P.; Gallego, G. M.; Marth, C. J.; Sarpong, R. "Synthesis of the Bridging Framework of Phragmalin-Type Limonoids" Org. Lett. 2012, 14, 2110–2113.

  71. Heller, S. T.; Fu T.; Sarpong, R. "Dual Brønsted Acid/Nucleophilic Activation of Carbonylimidazole Derivatives" Org. Lett. 2012, 14, 1970–1973.

  72. Gallego, G. M.; Sarpong, R. "Rh(I)-Catalyzed Enantioselective Intramolecular Hydroarylation of Unactivated Ketones with Aryl Pinacolboronic Esters" Chem. Sci. 2012, 3, 1338–1342.

  73. Schultz, E. E.; Pujanauski, B. G.; Sarpong, R. "Synthetic Studies toward Lapidilectine-Type Kopsia Alkaloids" Org. Lett. 2012, 14, 648–651.

  74. Murphy R. A.; Sarpong, R. "Direct Methoxypyridine Functionalization Approach to Magellanine-Type Lycopodium Alkaloids" Org. Lett. 2012, 14, 632–635.

  75. Narayan, A. R. H.; Sarpong, R. "Indolizinones as synthetic scaffolds: fundamental reactivity and the relay of stereochemical information" Org. Biomol. Chem. 2012, 10, 70–78.

  76. Heller, S. T.; Sarpong, R. "On The Reactivity Of Imidazole Carbamates And Ureas And Their Use As Esterification And Amidation Reagents" Tetrahedron 2011, 67, 8851–8859.

  77. Miller, L. C.; Sarpong, R. "Divergent reactions on racemic mixtures" Chem. Soc. Rev. 2011, 40, 4550–4562.

  78. Ford, K. A.; Casida, J. E.; Chandran, D.; Gulevich, A. G.; Okrent, R. A.; Durkin, K. A.; Sarpong, R.; Bunnelle, E. M. and Wildermuth, M. C. "Neonicotinoid insecticides induce salicylate- associated plant defense responses" PNAS 2010, 107 (41), 17527–17532.

  79. Heller, S. T.; Sarpong, R. "Chemoselective Esterification and Amidation of Carboxylic Acids with Imidazole Carbamates and Ureas" Org. Lett. 2010, 12 (20), 4572–4575.

  80. Marcus, A. P.; Sarpong, R. "Synthesis of the Tetracyclic Core of Tetrapetalone A Enabled by a Pyrrole Reductive Alkyation" Org. Lett. 2010, 12 (20), 4560–4563. (Org. Lett. 2014, 16, 3420 Correction)

  81. Gruver, J. M.; West, S. P.; Collum, D. B; Sarpong, R. "Experimental Characterization and Computational Study of Unique C,N-Chelated Lithium Dianions" J. Am. Chem. Soc. 2010, 132 (38), 13212–3213.

  82. Lian, Y.; Miller, L. C,; Born, S.; Sarpong, R.; Davies, H. M. L. "Catalyst-Controlled Formal [4 + 3] Cycloaddition Applied to the TotalSynthesis of (+)-Barekoxide and (-)-Barekol" J. Am. Chem. Soc. 2010, 132 (35) 12422–12425.

  83. Hardin-Narayan, A. R.; Sarpong, R. "Remarkable Facilitation of Hetero-Cycloisomerizations with Water and other Polar Protic Solvents: Metal-Free Synthesis of Indolizines" Green Chem. 2010, 10, 1556–1559.

  84. Hardin-Narayan, A. R.; Simmons, E. M.; Sarpong, R. "Synthetic Strategies Directed Towards the Cortistatin Family of Natural Products" Eur. J. Org. Chem. 2010, 19 3553–3567. (Review)

  85. Bisai, V.; Sarpong, R. "Methoxypyridines in the Synthesis of Lycopodium Alkaloids: Total Synthesis of (±)-Lycoposerramine R" Org. Lett. 2010, 12 (11), 2551–2553.

  86. Fischer, D. F.; Sarpong, R. "Total Synthesis of (+)-Complanadine A Using an Iridium-Catalyzed Pyridine C-H Functionalization" J. Am. Chem. Soc. 2010, 132(17) 5926–5927.

  87. Cortez, F. de J.; Sarpong, R. "Ga(III)-Catalyzed Cycloisomerization Approach to (±)-Icetexone and (±)-Epi-icetexone" Org. Lett.. 2010, 12(7) 1428–1431.

  88. Casida, J. E.; Gulevich, A. G.; Sarpong, R.; Bunnelle, E. M. "S-Arachidonoyl-2-thioglycerol synthesis and use for fluorimetric and colorimetric assays of monoacylglycerol lipase" Bioorganic & Medicinal Chemistry. 2010, 18, 1942–1947 .

  89. Simmons, E. M.; Hardin-Narayan, A. R.; Guo, X.; Sarpong R. "Formal total synthesis of (±)-Cortistatin A" Tetrahedron. 2010, 66(26), 4696–4700.

  90. Jeffrey, J. L.; Sarpong, R. "Concise Synthesis of Pauciflorol F Using a Larock Annulation" Org. Lett. 2009, 11, 5450–5453.

  91. Larson, K. K.; Sarpong, R. "Total Synthesis of Alkaloid (±)-G. B. 13 Using a Rh(I)-Catalyzed Ketone Hydroarylation and Late-Stage Pyridine Reduction" J. Am. Chem. Soc. 2009 131, 13244–13245.

  92. West, S. P.; Bisai, A.; Lim, A. D.; Narayan, R. R.; Sarpong, R. "Total Synthesis of (+)-Lyconadin A and Related Compounds Via Oxidative C-N Bond Formation" J. Am. Chem. Soc. 2009 131, 11187–11194 .

  93. Wood, J. L.; Pujanauski, B. G.; Sarpong, R. "Synthesis of the Tetracyclic Core of the Neomangicols Using a Late-Stage Indene Alkylation" Org. Lett. 2009,11, 3128–3131.

  94. Simmons, E. M.; Sarpong, R. "Structure, biosynthetic relationships and chemical synthesis of the icetexane diterpenoids" Nat. Prod. Rep. 2009, 26, 1195-1217. (Review)

  95. Jeffrey, J. L.; Sarpong, R. "An approach to the synthesis of dimeric resveratrol natural products via a palladium-catalyzed domino reaction." Tetrahedron Lett. 2009, 50, 1969–1972.

  96. Miller, L. C.; Ndungu, J. M.; Sarpong, R. "Parallel Kinetic Resolution Approach to the Cyathane and Cyanthiwigin Diterpenes Using a Cyclopropanation/Cope Rearrangement" Angew. Chem. Int. Ed. 2009, 48, 2398–2402.

  97. Simmons, E. M.; Hardin A. R.; Guo, X.; Sarpong, R. "Rapid Construction of the Cortistatin Pentacyclic Core" Angew. Chem. Int. Ed. 2008, 47, 6650–6653.

  98. Marcus, A. P.; Lee, A. S.; Davis, R. L.; Tantillo, D. J.; Sarpong, R. "Pronounced Steric Effects of Substituents in the Nazarov Cyclization of Aryl Dienyl Ketones" Angew. Chem. Int. Ed. 2008, 47, 6379–6383.

  99. Ly, T.; Liu, Z.; Pujanauski, B. G.; Sarpong, R.; Julian, R. R. "Surveying Ubiquitin Structure by Noncovalent Attachment of Distance Constrained Bis(crown) Ethers" Anal. Chem. 2008, 80, 5059–5064.

  100. Bisai, A.; West, S. P.; Sarpong, R. "Unified Strategy for the Synthesis of the 'Miscellaneous' Lycopodium Alkaloids: Total Synthesis of (±)-Lyconadin A" J. Am. Chem. Soc. 2008, 130, 7222–7223.

  101. Bunnelle, E. M.; Smith, C. R.; Lee, S. K.; Singaram, W. S.; Rhodes, A. J.; Sarpong, R. "Pt-catalyzed cyclization/migration of propargylic alcohols for the synthesis of 3(2H)-furanones, pyrrolones, indolizines, and indolizinones" Tetrahedron 2008, 64 (29), 7008–7014.

  102. Hardin, A. R.; Sarpong, R. "Electronic Effects in the Pt-Catalyzed Cycloisomerization of Propargylic Esters: Synthesis of 2,3-Disubstituted Indolizines as a Mechanistic Probe" Org. Lett. 2007, 9 (22), 4547–4550.

  103. Simmons, E. M.; Yen, J. R.; Sarpong, R. "Reconciling Icetexane Biosynthetic Connections with Their Chemical Synthesis: Total Synthesis of (±)-5,6-Dihydro-6r-hydroxysalviasperanol, (±)-Brussonol, and (±)-Abrotanone" Org. Lett. 2007, 9 (14), 2705–2708.

  104. Motamed, M.; Bunnelle, E. M.; Singaram, S. W.; Sarpong, R. "Pt(II)-Catalyzed Synthesis of 1,2-Dihydropyridines from Aziridinyl Propargylic Esters" Org. Lett. 2007, 9 (11), 2167–2170.

  105. Smith, C. R.; Bunnelle, E. M.; Rhodes, A. J.; Sarpong, R. "Pt-Catalyzed Cyclization/1,2-Migration for the Synthesis of Indolizines, Pyrrolones, and Indolizinones " Org. Lett. 2007, 9 (6), 1169–1171.

  106. Yao, T.; Hong, A.; Sarpong, R. "Synthesis of Multifunctionalized Furans from Diazoallenes: Rearrangement of 6-Methylenebicyclo[3.1.0]hexanes " Synthesis 2006, 21, 3605–3610.

  107. Simmons, E. M.; Sarpong, R. "Ga(III)-Catalyzed Cycloisomerization Strategy for the Synthesis of Icetexane Diterpenoids: Total Synthesis of (±)-Salviasperanol" Org. Lett. 2006, 8, 2883–2886.

  108. Pujanauski, B. G.; Prasad, B. A. B.; Sarpong, R. "Pt-Catalyzed Tandem Epoxide Fragmentation/Pentannulation of Propargylic Esters" J. Am. Chem. Soc. 2006, 128(21), 6786–6787.

  109. Ro, D.; Paradise, E. M.; Ouellet, M.; Fisher, K. J.; Newman, K. L.; Ndungu, J. M.; Ho, K. A.; Eachus, R. A.; Ham, T. S.; Kirby, J.; Chang, M. C. Y.; Withers, S. T.; Shiba, Y.; Sarpong, R.; Keasling, J. D. "Production of the Antimalarial Drug Precursor Artemisinic Acid in Engineered Yeast" Nature 2006, 440, 940–943.

  110. Ndungu, J. M.; Larson, K. K.; Sarpong, R. "Development of an Anomalous Heck Reaction: Skeletal Rearrangement of Divinyl and Enyne Carbinols" Org. Lett. 2005, 7 (26), 5845–5848.

  111. Prasad, B. A. B.; Yoshimoto, F. K.; Sarpong, R. "Pt-Catalyzed Pentannulations from In Situ Generated Metallo-Carbenoids Utilizing Propargyl Esters" J. Am. Chem. Soc. 2005, 127(36), 12468–12469.

  1. Jones, A.C.; May, J.A.; Sarpong, R.; Stoltz, B.M. "Toward a Symphony of Reactivity: Cascades Involving Catalysis and Sigmatropic Rearrangements" Angew. Chem. Int. Ed. 2014, 53, 2556–2591. (Review)

  2. Su, J.T.; Sarpong, R.; Stoltz, B.M.; Goddard III, W.A. "Substituent Effects and Nearly Degenerate Transition States: Rational Design of Substrates for the Tandem Wolff/Cope Reaction" J. Am. Chem. Soc. 2004, 126(1), 24–25.

  3. Sarpong, R.; Su, J. T.; Stoltz, B. M. "The Development of a Facile Tandem Wolff/Cope Rearrangement for the Synthesis of Fused Carbocyclic Skeletons" J. Am. Chem. Soc. 2003, 125(45), 13624–13625.

  4. Garg, N. K.; Sarpong, R.; Stoltz, B. M. "The first total synthesis of dragmacidin D" J. Am. Chem. Soc. 2002, 124(44), 13179–13184.

  1. Semmelhack, M.F.; Sarpong,R. "Kinetic Analysis of a Reactive Model Enediyne" J. Phys. Org. Chem. 2004, 17(9),807–813.

  2. Semmelhack, M. F.; Jaskowski, M. E.; Sarpong, R.; Ho, D. M. "A simple synthesis and evaluation of the bicyclo[8.3.0] enediyne framework" Tetrahedron Lett. 2002, 43(28), 4947–4950.

  3. Semmelhack, M. F.; Sarpong, R.; Bergman, J.; Ho, D. M. "Evaluation of alkene isomerization as a trigger for enediyne activation" Tetrahedron Lett. 2002, 43(4), 541–544.