4. Iridium-Catalyzed Allylic Substitution

Stanley, L.M.; Hartwig, J.F. “Mechanistically Driven Development of Iridium Catalysts for Asymmetric Allylic Substitution” Acc. Chem. Res. 2010 43, 1461-1475. [doi]

Stanley, L. M.; Bai, C.; Ueda, M.; Hartwig, J. F. “Iridium-Catalyzed Kinetic Asymmetric Transformations of Racemic Allylic Benzoates” J. Am. Chem. Soc. 2010, 132, 8918-8920. [doi]

Ueda, M.; Hartwig, J.F. “Iridium-Catalyzed Regio- and Enantioselective Allylic Substitution with Aromatic and Aliphatic Sulfinates” Org. Lett. 2009,12, 92-94. [doi]

Stanley, L.M.; Hartwig, J.F. “Iridium-Catalyzed Regio- and Enantioselective N-Allylation of Indoles” Angew. Chem. Int. Ed. 2009, 48, 7841-7844. [doi]

Pouy, M. J; Stanley, L. M.; Hartwig, J. F.Enantioselective, Iridium-Catalyzed Monoallylation of Ammonia. J. Am. Chem. Soc. 2009, 131, 11312–11313. [doi]

Weix, D. J.; Markovic, D.; Ueda, M.; Hartwig, J. F. Direct, Intermolecular, Enantioselective, Iridium-Catalyzed Allylation of Carbamates to Form Carbamate-Protected, Branched Allylic Amines. Org. Lett. 2009, 11, 2944–2947.[doi]

Stanley, L. M.; Hartwig, J. F. Regio- and Enantioselective N-Allylations of Imidazole, Benzimidazole, and Purine Heterocycles Catalyzed by Single-Component Metallacyclic Iridium Complexes. J. Am. Chem. Soc. 2009, 131, 8971–8983.[doi]

Madrahimov, S.T.; Markovic, D.; Hartwig, J .F. The Allyl Intermediate in Regioselective and Enantioselective Iridium-Catalyzed Asymmetric Allylic Substitution Reaction. J. Am. Chem. Soc. 2009, 131, 7228-7229.[doi]

Markovic, D. and J. F. Hartwig, Resting State and Kinetic Studies on the Asymmetric Allylic Substitutions Catalyzed by Iridium-Phosphoramidite Complexes. J. Am. Chem. Soc., 2007 129 (38) p. 11680-11681. [doi]

Pouy, M. J., Leitner, A., Weix, D. J., Ueno, S. and J. F. Hartwig, Enantioselective Iridium-Catalyzed Allylic Amination of Ammonia and Convenient Ammonia Surrogates. Org.Lett., 2007 9 (20) p. 3949-3952. [doi]

Weix, D. J. and J. F. Hartwig, Regioselective and Enantioselective Iridium-Catalyzed Allylation of Enamines. J. Amer. Chem. Soc., 2007. 129 (25): p. 7720-7721.
[doi]

Yamashita, Y., Gopalarathnam, A., and J. F. Hartwig, Iridium-Catalyzed, Asymmetric Amination of Allylic Alcohols Activated by Lewis Acids. J. Amer. Chem. Soc., 2007. 129 (24): p. 7508-7509.
[doi]

Shekhar, S., Trantow, B., Leitner, A., and J. F. Hartwig, Sequential Catalytic Isomerization and Allylic Substitution. Conversion of Racemic Branched Allylic Carbonates to Enantioenriched Allylic Substitution Products . J. Am. Chem. Soc., 2006. 128 (36): p. 11770-11771
[doi]

Graening, T. and J. F. Hartwig, Iridium-Catalyzed Regio- and Enantioselective Allylation of Ketone Enolates. J. Am. Chem. Soc., 2005. 127 (49): p. 17192-17193.
[doi]

Leitner, A., Shekhar, S., Pouy, M. J., and J. F. Hartwig, A Simple Iridium Catalyst with a Single Resolved Stereocenter for Enantioselective Allylic Amination. Catalyst Selection from Mechanistic Analysis. J. Am. Chem. Soc., 2005. 127 (44): p. 15506-15514.
[doi]

Leitner, A., Shu, C., and J. F. Hartwig, Effects of Catalyst Activation and Ligand Steric Properties on the Enantioselective Allylation of Amines and Phenoxides. Org. Lett., 2005. 7(6): 1093-1096.
[doi]

Shu, C., Leitner, A. and J. F. Hartwig, Enantioselective Allylation of Aromatic Amines after In Situ Generation of an Activated Cyclometalated Iridium Catalyst. Angewandte Chemie International Edition, 2004. 43 (36): p. 4797-4800.
[abstract]

Shu, C. and J. F. Hartwig, Iridium-Catalyzed Intermolecular Allylic Etherification with Aliphatic Alkoxides: Asymmetric Synthesis of Dihydropyrans and Dihydrofurans. Angewandte Chemie International Edition, 2004. 43 (36): p. 4794-4797.
[abstract]

Leitner, A., Shu, C., and J. F. Hartwig, Editing the Stereochemical Elements in an Iridium Catalyst for Enantioselective Allylic Amination. Proceedings of the National Academy of Sciences of the United States of America, 2004. 101 (16): p. 5830-5833.
[abstract]

Kiener, C. A., Shu, C., Incarvito, C. D., and J. F. Hartwig, Identification of an Activated Catalyst in the Iridium-Catalyzed Allylic Amination and Etherification. Increased Rates, Scope, and Selectivity. Journal of the American Chemical Society, 2003. 125 (47): p. 14272 -14273.
[doi]

Lopez, F., Ohmura, T., and J. F. Hartwig, Regio- and Enantioselective Iridium-Catalyzed Intermolecular Allylic Etherification of Achiral Allylic Carbonates with Phenoxides. Journal of the American Chemical Society, 2003. 125 (12): p. 3426-3427.
[doi]

Ohmura, T. and J. F. Hartwig, Regio- and enantioselective allylic amination of achiral allylic esters catalyzed by an iridium-phosphoramidite complex. Journal of the American Chemical Society, 2002. 124 (51): p. 15164-15165.
[doi]