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Tinoco Research Group Department of Chemistry University
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Welcome to
Tinoco Group
The sequence of
nucleotides in a nucleic acid determines its structure and function; Professor Tinoco and his
students want to deduce these fundamental properties from the sequence. Important questions are: • What folded, base
paired structure of an RNA is specified by the sequence? • How do RNA loops
interact with each other, or with double stranded regions to form compact
three-dimensional structures? • What proteins, drugs,
and ions do these structures bind? • How do the sequence
and structure affect the functions of ribosomal RNA's, the sites of
processing of RNA, the translation of messenger RNA's, the replication of RNA
viruses, and the catalytic abilities of RNA enzymes? Some
general things about RNA: PDF Audio This
site is maintained by Gang Chen. Send questions or comments by email. |