Williams Group

Gas-phase Ion Chemistry




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The Williams group develops methods, instrumentation, and theory in mass spectrometry, separations, spectroscopy, and biophysics with the general goals of understanding the structure, reactivity, and function of biomolecules.  

Recent Publications

  • Donald, W. A.; Leib, R. D.; O'Brien, J. T.;Williams, E. R. Directly Relating Gas-Phase Cluster Measurements to Solution-Phase Hydrolysis, the Absolute Standard Hydrogen Electrode Potential, and the Absolute Proton Solvation Energy  Chem. Eur. J. 2009, DOI: 10.1002/chem.200900334 . web
  • Leib, R. D.; Flick, T. G.; Williams, E. R. Direct Quantitation of Peptide Mixtures without Standards Using Clusters Formed by Electrospray Ionization Mass Spectrometry  Anal. Chem. 2009, DOI: 10.1021/ac900294r . web
  • O'Brien, J. T.; Prell, J. S.; Steill, J. D.; Oomens, J.; Williams, E. R. Changes in Binding Motif of Protonated Heterodimers Containing Valine and Amines Investigated Using IRMPD Spectroscopy between 800 and 3700 cm−1 and Theory   J. Am. Chem. Soc. 20091313905-3912. web



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