Publications

Publications by year: 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1990-1995

 

2014

303. Meniche, X.; Otten, R.; Siegrist, M. S.; Baer, C. E.; Murphy, K. C.; Bertozzi, C. R.; Sassetti, C. M. Subpolar addition of new cell wall is directed by DivIVA in mycobacteria. Proc. Natl. Acad. Sci. U. S. A. 2014, 111, E3243–E3251.

301. Paszek, M. J.; DuFort, C. C.; Rossier, O.; Bainer, R.; Mouw, J. K.; Godula, K.; Hudak, J. E.; Lakins, J. N.; Wijekoon, A. C.; Cassereau, L.; Rubashkin, M. G.; Magbanua, M. J.; Thorn, K. S.; Davidson, M. W.; Rugo, H. S.; Park, J. W.; Hammer, D. A.; Giannone, G.; Bertozzi, C. R.; Weaver, V. M. The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature 2014, 511, 319-325.

300. Smith, E. L.; Bertozzi, C. R.; Beatty, K. E. An Expanded Set of Fluorogenic Sulfatase Activity Probes. Chembiochem. 2014, 15, 1101-1105.

299. Shieh P.; Siegrist, M. S.; Cullen, A. J.; Bertozzi, C. R. Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes. Proc. Natl. Acad. Sci. U. S. A. 2014, 111, 5456-5461.

298. Smith, E. L.; Giddens, J. P.; Iavarone, A. T.; Godula, K.; Wang, L. X.; Bertozzi, C. R. Chemoenzymatic Fc Glycosylation via Engineered Aldehyde Tags. Bioconjug. Chem. 2014, 25,788-795.

297. Sletten, E. M.; de Almeida, G.; Bertozzi, C. R. A Homologation Approach to the Synthesis of Difluorinated Cycloalkynes. Org. Lett. 2014, 16, 1634-1637.

296. Beahm, B. J.; Dehnert, K. W.; Derr, N. L.; Kuhn, J.; Eberhart, J. K.; Spillmann, D,; Amacher, S. L.; Bertozzi, C. R. A Visualizable Chain-Terminating Inhibitor of Glycosaminoglycan Biosynthesis in Developing Zebrafish. Angew. Chem. Int. Ed. Engl. 2014, 53, 3347-3352.

295. Siegrist, M. S.; Bertozzi, C. R. Mycobacterial lipid logic. Cell Host Microbe. 2014, 15, 1-2.

2013

294. Hatzios, S. K.; Baer, C. E.; Rustad, T. R.; Siegrist, M. S.; Pang, J. M.; Ortega, C.; Alber, T.; Grundner, C.; Sherman, D. R.; Bertozzi, C. R. Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase. Proc. Natl. Acad. Sci. U. S. A. 2013, 110, E5069-E5077.

293. Hudak, J. E.; Canham, S. M.; Bertozzi, C. R. Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion. Nature Chem. Biol. 2013, 10, 69-75.

292. Hudak, J. E.; Bertozzi, C. R. Glycotherapy: New Advances Inspire a Reemergence of Glycans in Medicine. Chem. Biol. 2013, 21, 16-37.

291. Belardi, B.; de la Zerda, A.; Spiciarich, D. R.; Maund, S. L; Peehl, D. M.; Bertozzi, C. R. Imaging the glycosylation state of cell surface glycoproteins by two-photon fluorescence lifetime imaging microscopy. Angew. Chem. Int. Ed. Engl. 2013, 52, 14045-14049.

290. Bertozzi, C. R.; Wu, P. In vivo chemistry. Curr. Opin. Chem, Biol. 2013, 17, 717-718.

289. Palaniappan, K. K.; Hangauer, M. J.; Smith, T. J.; Smart, B. P.; Pitcher, A. A.; Cheng, E. H.; Bertozzi, C. R.; Boyce, M. A Chemical Glycoproteomics Platform Reveals O-GlcNAcylation of Mitochondrial Voltage-Dependent Anion Channel 2. Cell Rep. 2013, 5, 546-52.

288. Mauris, J.; Mantelli, F.; Woodward, A. M.; Cao, Z.; Bertozzi, C. R.; Panjwani, N.; Godula, K.; Argüeso, P. Modulation of Ocular Surface Glycocalyx Barrier Function by a Galectin-3 N-terminal Deletion Mutant and Membrane-Anchored Synthetic Glycopolymers. PLoS One 2013, 8, e72304.

287. Beatty, K. E.; Williams, M.; Carlson, B. L.; Swarts, B. M.; Warren, R. M.; van Helden, P. D.; Bertozzi, C. R. Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains. Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 12911-12916.

286. Sogi, K. M.; Gartner, Z. J.; Breidenbach, M. A.; Appel, M. J.; Schelle, M. W.; Bertozzi, C. R. Mycobacterium tuberculosis Rv3406 Is a Type II Alkyl Sulfatase Capable of Sulfate Scavenging. PLoS One 2013, 6, e65080.

285. Almeida, G. D.; Townsend, L. C.; Bertozzi, C. R. Synthesis and Reactivity of Dibenzoselenacycloheptynes. Org. Lett. 2013. Available ahead of print.

284. Shin, S. H.; Comolli, L, R.; Tscheliessnig, R.; Wang, C.; Nam, K. T.; Hexemer, A.; Siegerist, C. E.; De Yoreo, J. J.; Bertozzi, C. R. Self-Assembly of “S-Bilayers”, a Step Toward Expanding the Dimensionality of S-Layer Assemblies. A. C. S. Nano. 2013, 7, 4946-4953.

283. Comolli, L. R.; Siegerist, C. E.; Shin, S. H.; Bertozzi, C.; Regan, W.; Zettl, A.; De Yoreo, J. Conformational transitions at an S-layer growing boundary resolved by cryo-TEM. Angew. Chem. Int. Ed. Engl. 2013, 52, 4829-4832.

282. Van de Bittner, G. C.; Bertozzi, C. R.; Chang C. J. Strategy for dual-analyte luciferin imaging: in vivo bioluminescence detection of hydrogen peroxide and caspase activity in a murine model of acute inflammation. J. Am. Chem. Soc. 2013, 135, 1783-1795.

281. Siegrist, M. S.; Whiteside, S.; Jewett, J. C.; Aditham, A.; Cava, F.; Bertozzi, C. R. D-Amino Acid Chemical Reporters Reveal Peptidoglycan Dynamics of an Intracellular Pathogen. ACS Chem. Biol. 2013. 8, 500-505.

280. Agarwal, P.; van der Weijden, J.; Sletten, E. M.; Rabuka, D.; Bertozzi, C. R. A Pictet-Spengler ligation for protein chemical modification. Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 46-51.

2012

279. Shieh, P.; Hangauer, M. J.; Bertozzi, C. R. Fluorogenic Azidofluoresceins for Biological Imaging. J. Am. Chem. Soc. 2012, 134, 17428-17431.

278. Swarts, B. M.; Holsclaw, C. M.; Jewett, J. C.; Alber, M.; Fox, D. M.; Siegrist, M. S.; Leary, J. A.; Kalscheuer, R.; Bertozzi, C. R. Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry. J. Am. Chem. Soc. 2012, 134, 16123-16126.

277. Godula, K.; Bertozzi, C. R. Density Variant Glycan Microarray for Evaluating Cross-Linking of Mucin-like Glycoconjugates by Lectins. J. Am. Chem. Soc. 2012, 134, 15732-15742.

276. Henkin, A. H.; Cohen, A. S.; Dubikovskaya, E. A.; Park, H. M.; Nikitin, G. F.; Auzias, M. G.; Kazantzis, M.; Bertozzi, C. R.; Stahl, A. Real time non-invasive imaging of fatty acid uptake in vivo. A. C. S. Chem. Bio. 2012, 7 1884-1891.

275. Shin, S. H.; Chung S.; Sanii, B.; Comolli, L. R.; Bertozzi, C. R.; De Yoreo, J. J. Direct observation of kinetic traps associated with structural transformations leading to multiple pathways of S-layer assembly. Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 12968-12973.

274. Chang, P. V.; Bertozzi, C. R. Imaging beyond the proteome. Chem. Commun. (Camb). 2012. 48, 8864-8879.

273. Rabuka, D.; Rush, J. S.; deHart, G. W.; Wu, P.; Bertozzi, C. R.; Site-specific chemical protein conjugation using genetically encoded aldehyde tags. Nat. Protoc. 2012, 5, 1052-1067.

272. Gordon, C. G.; Mackey, J. L.; Jewett, J. C.; Sletten, E. M.; Houk, K. N.; Bertozzi, C. R.; Reactivity of Biarylazacyclooctynones in Copper-Free Click Chemistry. J. Am. Chem. Soc. 2012, 134, 9199-9208.

271. Belardi, B.; O'Donoghue, G. P.; Smith, A. W.; Groves, J. T.; Bertozzi, C. R. Investigating Cell Surface Galectin-Mediated Cross-linking on Glycoengineered Cells. J. Am. Chem. Soc. 2012, 134, 9549-9552.

270. Onoe, H.; Hsiao, S. C.; Douglas, E. S.; Gartner, Z. J.; Bertozzi, C. R.; Francis, M. B.; Mathies, R. A. Cellular Microfabrication: Observing Intercellular Interactions Using Lithographically-Defined DNA Capture Sequences. Langmuir 2012, 28, 8120-8126.

269. Yu, S. H.; Boyce, M.; Wands, A. M.; Bond, M. R.; Bertozzi, C. R.; Kohler, J. J. Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners. Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 4834-4839.

268. Hudak, J. E.; Barfield, R. M.; de Hart, G.W.; Grob, P.; Nogales, E.; Bertozzi, C.R.; Rabuka, D. Synthesis of Heterobifunctional Protein Fusions Using Copper-Free Click Chemistry and the Aldehyde Tag.. Angew Chem Int Ed Engl. 2012, 51, 4161-4165.

267. Griffin, J. E.; Pandey, A. K.; Gilmore, S. A.; Mizrahi, V.; McKinney, J. D.; Bertozzi, C. R.; Sassetti C.M. Cholesterol Catabolism by Mycobacterium tuberculosis Requires Transcriptional and Metabolic Adaptations. Chem Biol. 2012, 19, 218-227.

266. Gilmore, S. A.; Schelle, M. W.; Holsclaw, C. M.; Leigh, C. D.; Jain, M.; Cox, J. S.; Leary, J. A.; Bertozzi, C. R. Sulfolipid-1 Biosynthesis Restricts Mycobacterium tuberculosis Growth in Human Macrophages. ACS Chem Biol. 2012, 7, 863-870.

265. de Almeida, G.; Sletten, E. M.; Nakamura, H.; Palaniappan, K. K.; Bertozzi, C. R. Thiacycloalkynes for Copper-Free Click Chemistry. Angew Chem Int Ed Engl. 2012, 51, 2443-2447.

264. Seeliger, J. C.; Topp, S.; Sogi, K. M.; Previti, M. L.; Gallivan, J. P.; Bertozzi, C. R. A riboswitch-based inducible gene expression system for mycobacteria.. PLoS One. 2012, 7, e29266.

263. Dehnert, K. W.; Baskin, J. M.; Laughlin, S. T.; Beahm, B. J.; Naidu, N. N.; Amacher, S. L.; Bertozzi, C. R. Imaging the Sialome during Zebrafish Development with Copper-Free Click Chemistry. Chembiochem. 2012, 13, 353-357.

262. Breidenbach, M. A.; Palaniappan, K. K.; Pitcher, A. A.; Bertozzi, C. R. Mapping yeast N-glycosites with isotopically recoded glycans. Mol Cell Proteomics. 2012, 11, M111.015339.

261. Yao, J. Z.; Uttamapinant, C.; Poloukhtine, A. A.; Baskin, J. M.; Codelli, J. A.; Sletten, E. M.; Bertozzi, C. R.; Popik, V. V.; Ting, A. Y. Fluorophore targeting to cellular proteins via enzyme-mediated azide ligation and strain-promoted cycloaddition. J Am Chem Soc. 2012, 134, 3720-3728.

260. An, H. J.; Gip, P.; Kim, J.; Wu, S.; Park, K. W.; McVaugh, C. T.; Schaffer, D. V.; Bertozzi, C. R.; Lebirlla, C. B. Extensive Determination of Glycan Heterogeneity Reveals an Unusual Abundance of High-Mannose Glycans in Enriched Plasma Membranes of Human Embryonic Stem Cells Mol Cell Proteomics. 2012, 11, M111.010660.

259. Seeliger, J. C.; Holsclaw, C. M.; Schelle, M. W.; Botyanszki, Z.; Gilmore, S. A.; Tully, S. E.; Niederweis, M.; Cravatt, B. F.; Leary, J. A.; Bertozzi, C. R. Elucidation and Chemical Modulation of Sulfolipid-1 Biosynthesis in Mycobacterium tuberculosis. J Biol Chem. 2012, 287, 7990-8000.

2011

258. Jewett, J. C.; Bertozzi, C. R. Synthesis of a Fluorogenic Cyclooctyne Activated by Cu-Free Click Chemistry. Org Lett. 2011, 13, 5937-5939.

257. Bertozzi, C. R. A decade of bioorthogonal chemistry. Acc. Chem. Res 2011, 44, 651-653.

256. Sletten, E. M.; Bertozzi, C. R. A bioorthogonal quadricyclane ligation. J. Am. Chem. Soc. 2011, 133, 17570-17573.

255. Hudak, J. E.; Yu H. H.; Bertozzi, C. R. Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag. J. Am. Chem. Soc. 2011, 40, 16127-35.

254. Sletten, E. M.; Bertozzi, C. R. From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions. Acc Chem Res. 2011, 44, 666-676.

253. Boyce, M.; Bertozzi, C. R. Bringing chemistry to life. Nat Methods. 2011, 8, 638-642.

252. Hatzios, S. K.; Bertozzi, C. R. The Regulation of Sulfur Metabolism in Mycobacterium tuberculosis. PLoS Pathog. 2011, 7,e1002036.

251. Hatzios, S. K.; Schelle, M. W.; Newton, G. L.; Sogi, K. M.; Holsclaw, C. M.; Fahey, R. C.; Bertozzi, C. R. The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth. Bioorg Med Chem Lett. 2011, 21, 4945-4950.

250. Hubbard, S. C.; Boyce M.; McVaugh, C. T.; Peehl, D. M.; Bertozzi, C. R. Cell surface glycoproteomic analysis of prostate cancer-derived PC-3 cells. Bioorg Med Chem Lett. 2011, 21, 4945-4950.

249. Palaniappan, K. K.; Pitcher, A. A.; Smart, B. P.; Spiciarich, D. R.; Iavarone, A. T.; Bertozzi, C. R. Isotopic signature transfer and mass pattern prediction (IsoStamp): An enabling technique for chemically-directed proteomics. ACS Chem. Biol. 2011, 6, 829-836.

248. Dehnert, K. W.; Beahm, B. J.; Huynh, T. T.; Baskin, J. M.; Laughlin, S. T.; Wang, W.; Wu, P.; Amacher, S. L.; Bertozzi, C. R. Metabolic labeling of fucosylated glycans in developing zebrafish. ACS Chem. Biol. 2011, 6, 547-552.

247. Boyce, M.; Carrico, I. S.; Ganguli, A. S.; Yu, S.-H.; Hangauer, M. J.; Hubbard, S. C.; Kohler, J. J.; Bertozzi, C. R. Metabolic cross-talk allows labeling of O-linked ß-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway. Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 3141-3146.

246. Shui, W.; Petzold, C. J.; Redding, A.; Liu, J.; Pitcher, A.; Sheu, L.; Hsieh, T.; Keasling, J. D.; Bertozzi, C. R. Organelle membrane proteomics reveals differential influence of mycobacterial lipoglycans on macrophage phagosome maturation and autophagosome accumulation. J. Proteome Res. 2011, 10, 339-348.

245. Binda, O.; Boyce, M.; Rush, J. S.; Palaniappan, K. K.; Bertozzi, C. R.; Gozani, O. A chemical method for labeling lysine methyltransferase substrates. ChemBioChem 2011, 12, 330-334.

 

2010

244. Jasti, R.; Bertozzi, C. R. Progress and challenges for the bottom-up synthesis of carbon nanotubes with discrete chirality. Chem. Phys. Lett. 2010, 494, 1-7.

243. Van de Bittner, G. C.; Dubikovskaya, E. A.; Bertozzi, C. R.; Chang, C. J. In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 21316-21321.

242. Topp, S.; Reynoso, C. M.; Seeliger, J. C.; Goldlust, I. S.; Desai, S. K.; Murat, D.; Shen, A.; Puri, A. W.; Komeili, A.; Bertozzi, C. R.; Scott, J. R.; Gallivan, J. P. Synthetic riboswitches that induce gene expression in diverse bacterial species. Appl. Environ. Microbiol. 2010, 76, 7881-7884.

241. Rush, J. S.; Beatty, K. E.; Bertozzi, C. R. Bioluminescent probes of sulfatase activity. ChemBioChem 2010, 15, 2096-2099.

240. Beatty, K. E.; Fisk, J. D.; Smart, B. P.; Lu, Y. Y.; Szychowski, J.; Hangauer, M. J.; Baskin, J. M.; Bertozzi, C. R.; Tirrell, D. A. Live-cell imaging of cellular proteins by a strain-promoted azide-alkyne cycloaddition. ChemBioChem 2010, 15, 2092-2095.

239. Chung, S.; Shin, S.-H.; Bertozzi, C. R.; De Yoreo, J. J. Self-catalyzed growth of S layers via an amorphous-to-crystalline transition limited by folding kinetics. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 16536-16541.

238. Sletten, E. M.; Nakamura, H.; Jewett, J. C.; Bertozzi, C. R. Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin. J. Am. Chem. Soc. 2010, 132, 11799-11805.

237. Godula, K.; Bertozzi, C. R. Synthesis of glycopolymers for microarray applications via ligation of reducing sugars to a poly(acryloyl hydrazide) scaffold. J. Am. Chem. Soc. 2010, 132, 9963-9965.

236. Chang, P. V.; Dube, D. H.; Sletten, E. M.; Bertozzi, C. R. A strategy for the selective imaging of glycans using caged metabolic precursors. J. Am. Chem. Soc. 2010, 132, 9516-9518.

235. Baskin, J. M.; Bertozzi, C. R. Copper-free click chemistry: bioorthogonal reagents for tagging azides. Aldrichimica Acta 2010, 43, 15-23.

234. Cohen, A. S.; Dubikovskaya, E. A.; Rush, J. S.; Bertozzi, C. R. Real-time bioluminescence imaging of glycans on living cells. J. Am. Chem. Soc. 2010, 132, 8563-8565.

233. Baskin, J. M.; Dehnert, K. W.; Laughlin, S. T.; Amacher, S. L.; Bertozzi, C. R. Visualizing enveloping layer glycans during zebrafish early embryogenesis. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 10360-10365.

232. Muia, R. P.; Yu, H.; Prescher, J. A.; Hellman, U.; Chen, X.; Bertozzi, C. R.; Campetella, O. Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation. Glycobiology 2010, 20, 833-842.

231. Jewett, J. C.; Bertozzi, C. R. Cu-free click cycloaddition reactions in chemical biology. Chem. Soc. Rev. 2010, 39, 1272-1279.

230. Jewett, J. C.; Sletten, E. M.; Bertozzi, C. R. Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J. Am. Chem. Soc. 2010, 132, 3688-3690.

229. Breidenbach, M. A.; Gallagher, J. E. G.; King, D. S.; Smart, B. P.; Wu, P.; Bertozzi, C. R. Targeted metabolic labeling of yeast N-glycans with unnatural sugars. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 3988-3993.

228. Chang, P. V.; Prescher, J. A.; Sletten, E. M.; Baskin, J. M.; Miller, I. A.; Agard, N. J.; Lo, A.; Bertozzi, C. R. Copper-free click chemistry in living animals. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 1821-1826.

227. Yap, M. C.; Kostiuk, M. A.; Martin, D. D.; Perinpanayagam, M. A.; Hak, P. C.; Siddam, A.; Majjigapu, J. R.; Rajaiah, G.; Keller, B. O.; Prescher, J. A.; Wu, P.; Bertozzi, C. R.; Falck, J. R.; Berthiaume, L. G. Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. J. Lipid Res. 2010, 51, 1566-1580.

 

2009

226. Laughlin, S. T.; Bertozzi, C. R. In Vivo Imaging of Caenorhabditis elegans Glycans. ACS Chem. Biol. 2009, 4, 1068-1072.

225. Varki, A.; Cummings, R. D.; Esko, J. D.; Freeze, H. H.; Stanley, P.; Marth, J. D.; Bertozzi, C. R.; Hart, G. W.; Etzler, M. E. Symbol nomenclature for glycan representation. Proteomics 2009, 9, 5398-5399.

224. Sletten, E. M.; Bertozzi, C. R. Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality. Angew. Chem., Int. Ed. 2009, 48, 6974-6998.

223. Godula, K.; Umbel, M. L.; Rabuka, D.; Botyanszki, Z.; Bertozzi, C. R.; Parthasarathy, R. Control of the Molecular Orientation of Membrane-Anchored Biomimetic Glycopolymers. J. Am. Chem. Soc. 2009, 131, 10263-10268.

222. Drake, P. M.; Stock, C. M.; Nathan, J. K.; Gip, P.; Golden, K. P.; Weinhold, B.; Gerardy-Schahn, R.; Bertozzi, C. R. Polysialic acid governs T-cell development by regulating progenitor access to the thymus. Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 11995-12000.

221. Douglas, E. S.; Hsiao, S. C.; Onoe, H.; Bertozzi, C. R.; Francis, M. B.; Mathies, R. A. DNA-barcode directed capture and electrochemical metabolic analysis of single mammalian cells on a microelectrode array. Lab Chip 2009, 9, 2010-2015.

220. Hsiao, S.C.; Shum, B.J.; Onoe, H.; Douglas, E.S.; Gartner, Z.J.; Mathies, R.A.; Bertozzi, C.R.; Francis, M.B. Direct cell surface modification with DNA for the capture of primary cells and the investigation of myotube formation on defined patterns. Langmuir 2009, 25, 6985-6991.

219. Godula, K.; Rabuka, D.; Nam, K.T.; Bertozzi, C.R. Synthesis and Microcontact Printing of Dual End-Functionalized Mucin-Like Glycopolymers for Microarray Applications. Angew. Chem., Int. Ed. 2009, 48, 4973-4976.

218. Song, J.; Xu, J.; Filion, T.; Saiz, E.; Tomsia, A. P.; Lian, J. B.; Stein, G. S.; Ayers, D. C.; Bertozzi, C. R. Elastomeric high-mineral content hydrogel-hydroxyapatite composites for orthopedic applications. J. Biomed. Mater. Res. 2009, 89, 1098-1107.

217. Perrine, C. L.; Ganguli, A.; Wu, P.; Bertozzi, C. R.; Fritz, T. A.; Raman, J.; Tabak, L. A.; Gerken, T. A. The glycopeptdie preferring polypeptide-GalNAc transferase-10 (ppGalNAc T10), involved in mucin type-O-glycosylation, has a unique GalNAc-O-Ser/Thr binding site in its catalytic domain not found in ppGalNAc T1 or T2. J. Biol. Chem. 2009, 284, 20387-20397.

216. Nessen, M. A.; Kramer, G.; Back, J.; Baskin, J. M.; Smeenk, L. E.; Van Maarseveen, J.; de Koning, L. J.; de Jong, L.; Bertozzi, C.; Hiemstra, H.; de Koster, C. G. Selective Enrichment of Azide-Containing Peptides from Complex Mixtures. J. Proteome Res. 2009, 8, 3702-3711.

215. Chang, P. V.; Chen, X.; Smyrniotis, C.; Xenakis, A.; Hu, T.; Bertozzi, C. R.; Wu, P. Metabolic Labeling of Sialic Acids in Living Animals with Alkynyl Sugars. Angew. Chem., Int. Ed. 2009, 48, 4030-4033. [Download PDF]

214. Agard, N. J.; Bertozzi, C. R. Chemical Approaches to Perturb, Profile, and Perceive Glycans. Acc. Chem. Res. 2009, 42, 788-797.

213. Hur, G. H.; Meier, J. L.; Baskin, J.; Codelli, J. A.; Bertozzi, C. R.; Marahiel, M. A.; Burkart, M. D. Crosslinking Studies of Protein-Protein Interactions in Nonribosomal Peptide Biosynthesis. Chem. Biol. 2009, 16, 372-381.

212. Harland, C. W.; Botyanszki, Z.; Rabuka, D.; Bertozzi, C. R.; Parthasarathy, R. Synthetic Trehalose Glycolipids Confer Dessication Resistance to Supported Lipid Monolayers. Langmuir 2009, 25, 5193-5198.

211. Barb, A. W.; Leavy, T. M.; Robins, L. I.; Guan, Z.; Six, D. A.; Zhou, P.; Bertozzi, C. R.; Raetz, C. R. Uridine-Based Inhibitors as New Leads for Antibiotics Targeting Escherichia coli LpxC. Biochemistry 2009, 48, 3068-3077.

210. Gartner, Z. J.; Bertozzi, C. R. Programmed assembly of 3-dimensional microtissues with defined cellular connectivity. Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 4606-4610.

209. Hatzios, S. K.; Schelle, M. W.; Holsclaw, C. M.; Behrens, C. R.; Botyanszki, Z.; Lin, F. L.; Carlson, B. L.; Kumar, P.; Leary, J. A.; Bertozzi, C. R. PapA3 is an acyltransferase required for Polyacyltrehalose biosynthesis in Mycobacterium tuberculosis. J. Biol. Chem. 2009, 284, 12745-12751.

208. Wu, P.; Shui, W.; Carlson, B. L.; Hu, N.; Rabuka, D.; Lee, J.; Bertozzi, C. R. Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag. Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 3000-3005.

207. Chen, X.; Wu, P.; Rousseas, M.; Okawa, D.; Gartner, Z.; Zettl, A.; Bertozzi, C. R. Boron Nitride Nanotubes Are Noncytotoxic and Can Be Functionalized for Interaction with Proteins and Cells. J. Am. Chem. Soc. 2009, 131, 890-891.

206. Laughlin, S. T.; Bertozzi, C. R. Imaging the Glycome. Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 12-17.

 

2008

205. Wu, P.; Chen, X.; Hu, N.; Tam, U. C.; Blixt, O.; Zettl, A.; Bertozzi, C. R. Biocompatible carbon nanotubes generated by functionalization with glycodendrimers. Angew. Chem., Int. Ed. 2008, 47, 5022-5025. [Download PDF]

204. Toriello, N. M.; Douglas, E. S.; Thaitrong, N.; Hsiao, S. C.; Francis, M. B.; Bertozzi, C. R.; Mathies, R. A. Integrated Microfluidic Bioprocessor for Single-Cell Gene Expression Analysis. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 20173-20178.

203. Shui, W.; Gilmore, S. A.; Sheu, L.; Liu, J.; Keasling, J. D.; Bertozzi, C. R. Quantitative Proteomic Profiling of Host-Pathogen Interactions: The Macrophage Response to Mycobacterium tuberculosis Lipids. J. Prot. Res. 2008, 8, 282-289.

202. Jasti, R.; Bhattacharjee, J.; Neaton, J. B.; Bertozzi, C. R. Synthesis, Characterization, and Theory of [9]-, [12]-, and [18]Cycloparaphenylene: Carbon Nanohoop Structures. J. Am. Chem. Soc. 2008, 130, 17646-17647.

201. Drake, P. M.; Nathan, J. K.; Stock, C. M.; Chang, P. V.; Muench, M. O.; Nakata, D.; Reader, J. R.; Gip, P.; Golden, K. P.; Weinhold, B.; Gerardy-Schahn, R.; Troy, F. A. 2nd, Bertozzi, C. R. Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses. J. Immunol. 2008, 181, 6850-6858.

200. Shui, W.; Sheu, L.; Liu, J.; Smart, B.; Petzold, C. J.; Hsieh, T. Y.; Pitcher, A.; Keasling, J. D.; Bertozzi, C. R. Membrane proteomics of phagosomes suggests a connection to autophagy. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 16952-16957.

199. Holsclaw, C. M.; Sogi, K. M.; Gilmore, S. A.; Schelle, M. W.; Leavell, M. D.; Bertozzi, C. R.; Leary, J. A. Structural Characterization of a Novel Sulfated Menaquinone produced by stf3 from Mycobacterium tuberculosis. ACS Chem. Biol. 2008, 3, 619-624.

198. Hsiao, S. C.; Crow, A. K.; Lam, W. A.; Bertozzi, C. R.; Fletcher, D. A.; Francis, M. B. DNA-Coated AFM Cantilevers for the Investigation of Cell Adhesion and the Patterning of Live Cells. Angew. Chem., Int. Ed. 2008, 120, 8601-8605.

197. Czlapinski, J. L.; Schelle, M. W.; Miller, L. W.; Laughlin, S. T.; Kohler, J. J.; Cornish, V. W.; Bertozzi, C. R. Conditional Glycosylation in Eukaryotic Cells Using a Biocompatible Chemical Inducer of Dimerization. J. Am. Chem. Soc. 2008, 130, 13186-13187.

196. Rush, J. S.; Bertozzi, C. R. New Aldehyde Tag Sequences Identified by Screening Formylglycine Generating Enzymes in Vitro and in Vivo. J. Am. Chem. Soc. 2008, 130, 12240-12241.

195. Codelli, J. A.; Baskin, J. M.; Agard, N. J.; Bertozzi, C. R. Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry. J. Am. Chem. Soc. 2008, 130, 11486-11493.

194. Johnson, J. A.; Baskin, J. M.; Bertozzi, C. R.; Koberstein, J. T.; Turro, N. J. Copper-free click chemistry for the in situ crosslinking of photodegradable star polymers. Chem. Commun. 2008, 3064-3066.

193. Paulick, M. G.; Bertozzi, C. R. The Glycosylphosphatidylinositol Anchor: A Complex Membrane-Anchoring Structure for Proteins. Biochemistry 2008, 47, 6991-7000.

192. Sletten, E. M.; Bertozzi, C. R. A Hydrophilic Azacyclooctyne for Cu-Free Click Chemistry. Org. Lett. 2008, 10, 3097-3099.

191. Hatzios, S. K.; Iavarone, A. T.; Bertozzi, C. R. Rv2131c from Mycobacterium tuberculosis Is a CysQ 3'-Phosphoadenosine-5'-phosphatase. Biochemistry 2008, 47, 5823-5831.

190. Laughlin, S. T.; Baskin, J. M.; Amacher, S. L.; Bertozzi, C. R. In vivo imaging of membrane-associated glycans in developing zebrafish. Science 2008, 320, 664-667.

189. Rabuka, D.; Forstner, M. B.; Groves, J. T.; Bertozzi, C. R. Noncovalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes. J. Am. Chem. Soc. 2008, 130, 5947-5953.

188. Harland, C. W.; Rabuka, D.; Bertozzi, C. R.; Parthasarathy, R. The Mycobacterium tuberculosis Virulence Factor Trehalose Dimycolate Imparts Desiccation Resistance to Model Mycobacterial Membranes. Biophys. J. 2008, 94, 4718-4724.

187. Carlson, B. L.; Ballister, E. R.; Skordalakes, E.; King, D. S.; Breidenbach, M. A.; Gilmore, S. A.; Berger, J. M.; Bertozzi, C. R. Function and structure of a prokaryotic formylglycine-generating enzyme. J. Biol. Chem. 2008, 283, 20117-20125.

186. Hangauer, M. J.; Bertozzi, C. R. A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation. Angew. Chem., Int. Ed. 2008, 47, 2394-2397.

185. Leigh, C. D.; Bertozzi, C. R. Synthetic Studies toward Mycobacterium tuberculosis Sulfolipid-I. J. Org. Chem. 2008, 73, 1008-1017.

184. Martin, D. D.; Vilas, G. L.; Prescher, J. A.; Rajaiah, G.; Falck, J. R.; Bertozzi, C. R.; Berthiaume, L. G. Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog. FASEB J. 2008, 22, 797-806.

183. Kostiuk, M. A.; Corvi, M. M.; Keller, B. O.; Plummer, G.; Prescher, J. A.; Hangauer, M. J.; Bertozzi, C. R.; Rajaiah, G.; Falck, J. R.; Berthiaume, L. G. Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue. FASEB J. 2008, 22, 721-732.

182. Bertozzi, C. R.; Schelle, M. W. Sulfated Metabolites from Mycobacterium tuberculosis: Sulfolipid-1 and Beyond. In The Mycobacterial Cell Envelope, D. Mamadou & J.-M. Reyrat, Editors. ASM Press (Washington, DC), 2008.

 

2007

181. Baskin, J. M.; Bertozzi, C. R. Bioorthogonal Click Chemistry: Covalent Labeling in Living Systems. QSAR Comb. Sci. 2007, 26, 1211-1219.

180. Paulick, M. G.; Forstner, M. B.; Groves, J. T.; Bertozzi, C. R. A chemical approach to unraveling the biological function of the glycosylphosphatidylinositol anchor. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 20332-20337.

179. Fernandez-Suarez, M.; Baruah, H.; Martinez-Hernandez, L.; Xie, K. T.; Baskin, J. M.; Bertozzi, C. R.; Ting, A. Y. Redirecting lipoic acid ligase for cell surface protein labeling with small-molecule probes. Nat. Biotechnol. 2007, 25, 1483-1487.

178. Douglas, E. S.; Chandra, R. A.; Bertozzi, C. R.; Mathies, R. A.; Francis, M. B. Self-assembled cellular microarrays patterned using DNA barcodes. Lab Chip 2007, 7, 1442-1448.

177. Parthasarathy, R.; Rabuka, D.; Bertozzi, C. R.; Groves, J. T. Molecular orientation of membrane-anchored mucin glycoprotein mimics. J. Phys. Chem. B. 2007, 111, 12133-12135.

176. Baskin, J. M.; Prescher, J. A.; Laughlin, S. T.; Agard, N. J.; Chang, P. V.; Miller, I. A.; Lo, A.; Codelli, J. A.; Bertozzi, C. R. Copper-free click chemistry for dynamic in vivo imaging. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 16793-16797.

175. Paulick, M. G.; Wise, A. R.; Forstner, M. B.; Groves, J. T.; Bertozzi, C. R. Synthetic analogues of glycosylphosphatidylinositol-anchored proteins and their behavior in supported lipid bilayers. J. Am. Chem. Soc. 2007, 129, 11543-11550.

174. Laughlin, S. T.; Bertozzi, C. R. Metabolic labeling of glycans with azido sugars and subsequent glycan-profiling and visualization via Staudinger ligation. Nat. Protoc. 2007, 2, 2930-2944.

173. Lin, F. L.; van Halbeek, H.; Bertozzi, C. R.  Synthesis of Mono- and Dideoxygenated a,a-Trehalose Analogs.  Carbohydr. Res. 2007, 342, 2014-2030.

172. Chang. P. V.; Prescher, J. A.; Hangauer, M. J.; Bertozzi, C. R.  Imaging Cell Surface Glycans with Bioorthogonal Chemical Reporters.  J. Am. Chem. Soc. 2007, 129, 8400-8401.

171. Kumar, P.; Schelle, M. W.; Jain, M.; Lin, F. L.; Petzold, C. J.; Leavell, M. D.; Leary, J. A.; Cox, J. S.; Bertozzi, C. R.  PapA1 and PapA2 are Acyltransferases Essential for the Biosynthesis of the Mycobacterium tuberculosis Virulence Factor Sulfolipid-1.  Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 11221-11226.

170. Leavy, T. L.; Bertozzi, C. R.  A High-Throughput Assay for O-GlcNAc Transferase Detects Primary Sequence Preferences in Peptide Substrates. Bioorg. Med. Chem. Lett. 2007, 7, 3851-3854.

169. Rabuka, D.; Parthasarathy, R.; Lee, G. S.; Chen, X.; Groves, J. T.; Bertozzi, C. R. Hierarchical Assembly of Model Cell Surfaces: Synthesis of Mucin Mimetic Polymers and Their Display on Supported Bilayers. J. Am. Chem. Soc. 2007, 129, 5462-5471.

168. Carrico, I. S.; Carlson, B. L.; Bertozzi, C. R. Introducing Genetically Encoded Aldehydes into Proteins.  Nature Chem. Biol. 2007, 3, 321-322.

167. Jain, M; Petzold, C.J.; Schelle, M.W.; Leavell, M.D.; Mougous, J.D.; Bertozzi, C.R.; Leary, J.A.; Cox, J.S. Lipidomics Reveals Control of Mycobacterium tuberculosis Virulence Lipids via Metabolic Coupling. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 5133-5138.

166. Chen, X.; Kis, A.; Zettl, Z.; Bertozzi, C. R. A Cell Nanoinjector Based on Carbon Nanotubes. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 8218-8222.

165. Senaratne, R. H.; Mougous, J. D.; Reader, J. R.; Williams, S. J.; Zhang, T.; Bertozzi, C. R.; Riley, L. W.  Vaccine Efficacy of Attenuated but Persistent Mycobacterium tuberculosis cysH Mutant. J. Med. Microbiol. 2007, 56, 454-458.

164. Gao, H.; Leary, J.; Carroll, K. S.; Bertozzi, C. R.; Chen, H. Noncovalent Complexes of APS Reductase from M. tuberculosis: Delineating a Mechanistic Model Using ESI-FTICR MS.  J. Am. Soc. Mass Spectrom. 2007, 18, 167-178.

 

2006

163. Laughlin, S. T.; Agard, N. J.; Baskin, J. M.; Carrico, I. S.; Chang, P. V.; Ganguli, A. S.; Hangauer, M. J.; Lo, A.; Prescher, J. A.; Bertozzi, C. R. Metabolic Labeling of Glycans with Azido Sugars for Visualization and Glycoproteomics.  Methods Enzymol. 2006, 415, 230-250.

162. Czlapinski, J. L.; Bertozzi, C. R.  Synthetic Glycobiology: Exploits in the Golgi Compartment.  Curr. Opin. Chem. Biol. 2006, 10, 645-51.

161. Agard, N. J.; Baskin, J. M.; Prescher, J. A.; Lo, A.; Bertozzi, C. R.  A Comparative Study of Bioorthogonal Reactions with Azides.  ACS Chem. Biol. 2006, 1, 644-8.

160. Kehoe, J. W.; Velappan, N.; Walbolt, M.; Rasmussen, J.; King, D.; Lou, J.; Knopp, K.; Pavlik, P.; Marks, J.; Bertozzi, C. R.; Bradbury, A. R. M.   Using Phage Display to Select Antibodies Recognizing Post-translational Modifications Independently of Sequence Context.  Mol. Cell. Proteomics 2006, 5, 2350-63.

159. Chartron, J.; Carroll, K. S.; Shiau, C.; Gao, H.; Leary, J. A.; Bertozzi, C. R.; Stout, C. D.  Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5’-Phosphosulfate Reductase.  J. Mol. Biol. 2006 364, 152-69.

158. Rabuka, D.; Hubbard, S. C.; Laughlin, S. T.; Argade, S. P.; Bertozzi, C. R.  A Chemical Reporter Strategy to Probe Glycoprotein Fucosylation. J. Am. Chem. Soc. 2006, 128, 12078-9.

157. Schelle, M. W.; Bertozzi, C. R.  Sulfate Metabolism in Mycobacteria. ChemBioChem 2006, 7, 1516-24.

156. Prescher, J. A.; Bertozzi, C. R.  Chemical Technologies for Probing Glycans. Cell  2006, 126, 851-854.

155. Stowell, C. L.; Barvian, K. K.; Young, P. C.; Bigsby, R. M.; Verdugo, D. E.; Bertozzi, C. R.; Widlanski, T. S.  A Role for Sulfation-Desulfation in the Uptake of Bisphenol A Into Breast Tumor Cells.  Chem. Biol. 2006, 13, 891-897.

154. Link, A. J.; Vink, M. K.; Agard, N. J.; Prescher, J. A.; Bertozzi, C. R.; Tirrell, D. A.  Discovery of Aminoacyl-tRNA Synthetase Activity Through Cell Surface Display of Noncanonical Amino Acids.  Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 10180-5.

153. Chen, X.; Tam, U. C.; Czlapinski, J. L.; Lee, G. S.; Rabuka, D.; Zettl, A.; Bertozzi, C. R.  Interfacing Carbon Nanotubes with Living Cells.  J. Am. Chem. Soc. 2006, 128, 6292-3.

152. Dube, D. H.; Prescher, J. A.; Quang, C. N.; Bertozzi, C. R.  Probing Mucin-type O-linked Glycosylation in Living Animals.  Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 4819-24.

151. Juan Perez-Vilar, Raean Mabolo, Cheryl T. McVaugh, Carolyn R. Bertozzi, and Richard C. Boucher. Mucin Granule Intraluminal Organization in Living Mucous/Goblet Cells. Roles of Protein Post-translational Modifications and Secretion. J. Biol. Chem. 2006, 281, 4844-55.

150. Senaratne, R. H.; DeSilva, D.; Williams, S. J.; Mougous, J. D.; Zhang, T.; Chan, S.; Sidders, B.; Chan, J.; Bertozzi, C. R.; W. Riley, L. W. 5’-Adenosinephosphosulphate Reductase (CysH) Protects Mycobacterium tuberculosis Against Free Radicals During Chronic Infection Phase in Mice. Mol. Microbiol. 2006, 59, 1744-53.

149. Mougous, J. D.; Senaratne, R. H.; Petzold, C. J.; Jain, M.; Lee, D. H.; Schelle, M. W.; Leavell, M. D.; Cox, J. S.; Leary, J. A.; Riley, L. W.; Bertozzi, C. R.  A Sulfated Metabolite Produced by stf3 Negatively Regulates the Virulence of Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 4258-63.

148. Rush, J. S.; Bertozzi, C. R. An a-formylglycine building block for Fmoc-based solid phase peptide synthesis. Org. Lett. 2006, 8, 131-134.

147. Mougous, J. D.; Lee, D. H.; Hubbard, S. C.; Schelle, M. W.; Vocadlo, D. J.; Berger, J. M.; Bertozzi, C. R. Molecular Basis for G protein Control of ATP Sulfurylase in Bacteria. Molecular Cell 2006, 21, 109-122.

146. Chandra, R. A.; Douglas, E. S.; Mathies, R. A.; Bertozzi, C. R.; Francis, M. B. Programmable Cell Adhesion Encoded by DNA Hybridization.  Angew. Chem., Int. Ed. 2006, 45, 896-901.

 

2005

145. Carroll, K. S.; Gao, H.; Chen, H.; Leary, J. A.; Bertozzi, C. R. Investigation of the Iron-Sulfur Cluster in Mycobacterium tuberculosis APS Reductase: Implications for Substrate Binding and Catalysis. Biochemistry 2005, 44, 14647-14657.

144. Tomsia, A. P.; Saiz, E.; Song, J.; Bertozzi, C. R. Biomimetic Bonelike Composites and Novel Bioactive Glass Coatings. Adv. Eng. Mater. 2005, 7, 999-1004.

143. Hang, H. C.; Bertozzi, C. R. The Chemistry and Biology of Mucin-Type O-Linked Glycosylation. Bioorg. Med. Chem. 2005, 13, 5021-5034.

142. Carroll, K. S.; Gao, H.; Chen, H.; Stout, C. D.; Leary, J. A.; Bertozzi, C. R. A Conserved Mechanism for Sulfonucleotide Reduction.  PloS Biology 2005, 3 (8), e250.

141. Grogan, M. J.; Kaizuka, Y.; Conrad, R. M.; Groves, J. T.; Bertozzi, C. R.  Synthesis of Lipidated Green Fluorescent Protein and its Incorporation in Supported Lipid Bilayers.  J. Am. Chem. Soc., 2005, 127, 14383-14387.

140. Prescher, J. A.; Bertozzi, C. R. Chemistry in Living Systems. Nature Chem. Biol. 2005, 1, 13-21.

139. Dube, D. H.; Bertozzi, C. R. Glycans in Cancer and Inflammation – Potential for Therapeutics and Diagnostics.  Nature Rev. Drug Disc. 2005, 4, 477-88.

138. Saad, O. M.; Ebel, H.; Uchimura, K.; Rosen, S. D.; Bertozzi, C. R.; Leary, J. A. Compositional Profiling of Heparin/Heparan Sulfate Using Mass Spectrometry: Assay for Specificity of a Novel Extracellular Human Endosulfatase.  Glycobiology 2005, 15, 818-826.

137. Pi, N.; Hoang, M. B.; Gao, H.; Mougous, J. D.; Bertozzi, C. R.; Leary, J. A. Kinetic Measurements and Mechanism Determination of Stf0 Sulfotransferase Using Mass Spectrometry.  Anal. Biochem. 2005, 341, 94-104.

136. Song, J.; Malathong, V.; Bertozzi, C. R. Mineralization of Synthetic Polymer Scaffolds: A Bottom-up Approach for the Development of Artificial Bone. J. Am. Chem. Soc. 2005, 127, 3366-3372.

135. Lin, F., Hoyt, H. M.; van Halbeek, H.; Bergman, R. G.; Bertozzi, C. R.  Mechanistic Investigation of the Staudinger Ligation.  J. Am. Chem. Soc. 2005, 127, 2686-2695.

134. Pratt, M. R.; Bertozzi, C. R. Synthetic Glycopeptides and Glycoproteins as Tools for Biology and as Therapeutic Agents.  Chem. Soc. Rev. 2005, 34, 58-68.

 

2004

133. Samuel, J.; Bertozzi, C. R. Chemical Tools for the Study of Polysialic Acid. Trends in Glycoscience 2004, 91, 305-318.

132. Vocadlo, D. J.; Bertozzi, C. R. A Strategy for Functional Proteomic Analysis of Glycosidase Activity from Cell Lysates.  Angew. Chem., Int. Ed. 2004, 43, 5338-5342.

131. Tian, E.; Ten Hagen, K. G.; Shum, L.; Hang, H. C.; Imbert, Y.; Young, W. W., Jr.; Bertozzi, C. R.; Tabak, L. A.  An Inhibitor of O-Glycosylation Induces Apoptosis in NIH3T3 Cells and Developing Mouse Embryonic Mandibular Tissues.  J. Biol. Chem. 2004, 279, 50382-50390.

130. Agard, N. J.; Prescher, J. A.; Bertozzi, C. R.  A Strain-Promoted [3+2] Azide-Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems.  J. Am. Chem. Soc. 2004, 126, 15046-15047.

129. Song, J.; Bertozzi, C. R. Functional Polymers for Bone Tissue Engineering Applications, In Handbook of Nanostructured Materials and Their Applications in Nanobiotechnology, H. S. Nalwa, Editor.  American Scientific Publishers, 2005. Vol 1, pp 1-22.

128. Chen, X.; Lee, G. S.; Zettl, A.; Bertozzi, C. R. Biomimetic Engineering of Carbon Nanotubes By Using Cell Surface Mimics.  Angew. Chem., Int. Ed. 2004, 43, 6112-6116.

127. Luchansky, S. J.; Argade, S.; Hayes, B. K.; Bertozzi, C. R. Metabolic Functionalization of Recombinant Glycoproteins. Biochemistry 2004, 43, 12358-12366.

126. Prescher, J. A.; Dube, D. H.; Bertozzi, C. R. Chemical Remodelling of Cell Surfaces in Living Animals. Nature 2004, 430, 873-877.

125. Luchansky, S. J.; Bertozzi, C. R. Azido Sialic Acids can Modulate Cell Surface Interactions. ChemBioChem 2004, 5, 1706-1709.

124. Kohler, J. J.; Czlapinski, J. L.; Laughlin, S. T.; Schelle, M. W.; de Graffenried, C. L.; Bertozzi, C. R. Directing Flux in Glycan Biosynthetic Pathways with a Small Molecule Switch. ChemBioChem 2004, 5, 1455-1458.

123. de Graffenried, C. L.; Laughlin, S. T.; Kohler, J. J.; Bertozzi, C. R. A Small-Molecule Switch for Golgi Sulfotransferases.  Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 16715-16720.

122. de Graffenried, C. L.; Bertozzi, C. R. The Stem Region of the Sulfotransferase GlcNAc6ST-1 is a Determinant of Substrate Specificity.  J. Biol. Chem. 2004, 279, 40035-40043.

121. Song, J.; Chen, J.; Klapperich, C. M.; Eng, V.; Bertozzi, C. R. Functional Glass Slides for In Vitro Evaluation of Interactions Between Osteosarcoma TE85 Cells and Mineral-Binding Ligands.  J. Mat. Chem. 2004, 14, 2643-2648.

120. de Graffenried, C. L.; Bertozzi, C. R. The Roles of Enzyme Localisation and Complex Formation in Glycan Assembly within the Golgi Apparatus. Curr. Opin. Cell Biol. 2004, 16, 356-363.

119. Song, J.; Cisar, J. S.; Bertozzi, C. R. Functional Self-Assembling Bolaamphiphilic Polydiacetylenes as Colorimetric Sensor Scaffolds. J. Am. Chem. Soc. 2004, 126, 8459-8465.

118. Mougous, J. D.; Petzold, C. J.; Senaratne, R. H.; Lee, D. H.; Akey, D. L.; Lin, F. L.; Munchel, S. E.; Pratt, M. R.; Riley, L. W.; Leary, J. A.; Berger, J. M.; Bertozzi, C. R. Identification, Function and Structure of the Mycobacterial Sulfotransferase that Initiates Sulfolipid-1 Biosynthesis. Nature Struct. Mol. Biol. 2004, 11, 721-729.

117. Woodruff, P. J.; Carlson, B. L.; Siridechadilok, B.; Pratt, M. R.; Mougous, J. D.; Senaratne, R.; Riley, L. W.; Williams, S. J.; Bertozzi, C. R.  Trehalose is Required for Growth of Mycobacterium smegmatis.  J. Biol. Chem. 2004, 279, 28835-28843.

116. Pratt, M. R.; Bertozzi, C. R. Syntheses of 6-Sulfo Sialyl Lewis X Glycans Corresponding to the L-Selectin Ligand “Sulfoadhesin”. Org. Lett. 2004, 6, 345-2348.

115. Pratt, M. R.; Hang, H. C.; Ten Hagen, K. G.; Rarick, J.; Gerken, T. A.; Tabak, L. A.; Bertozzi, C. R.  Deconvoluting the Functions of Polypeptide N-a-Acetylgalactosaminyltransferase (ppGalNAcT) Family Members by Glycopeptide Substrate Profiling. Chem. Biol. 2004, 11, 1009-1016.

114. Klapperich, C. M.; Bertozzi, C. R. Global Gene Expression Patterns of Cells Attached to a Tissue Engineering Scaffold. Biomaterials 2004, 25, 5631-5641.

113. Macmillan, D.; Bertozzi, C. R. Modular Assembly of Glycoproteins: Toward the Synthesis of GlyCAM-1 by Using Expressed Protein Ligation.  Angew. Chem., Int. Ed. 2004, 43, 1355-1359.

112. Hang, H. C.; Yu, C.; Ten Hagen, K. G.; Tian, E.; Winans, K. A.; Tabak, L. A.; Bertozzi, C. R. Small Molecule Inhibitors of Mucin-type O-Linked Glycosylation from a Uridine-based Library. Chem. Biol. 2004, 11, 337-345.

111. Grossman,  H. L.; Myers, W. R.; Vreeland, V. J.; Bruehl, R.; Alper, M. D.; Bertozzi, C. R.; Clarke, J.  Detection of Bacteria in Suspension by Using a Superconducting Quantum Interference Device. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 129-134.

110. Luchansky, S. J.; Goon, S.; Bertozzi, C. R. Expanding the Diversity of Unnatural Cell Surface Sialic Acids. ChemBioChem 2004, 5, 371-374.

109. Hang, H. C.; Yu, C.; Pratt, M. R.; Bertozzi, C. R. Probing Glycosyltransferase Activities with the Staudinger Ligation. J. Am. Chem. Soc. 2004, 126, 6-7.

 

2003

108. Hang, H. C.; Yu, C.; Kato, D. L.; Bertozzi, C. R. A Metabolic Labeling Approach Towards Proteomic Analysis of Mucin-type O-Linked Glycosylation. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 14846-14851.

107. Kohler, J. J.; Bertozzi, C. R. Regulating Cell Surface Glycosylation by Small Molecule Control of Enzyme Localization. Chem. Biol. 2003, 10, 1303-1311.

106. Verdugo, D. E.; Pedersen, L. C.; Bertozzi, C. R. Small Molecule Inhibitors of the Sulfotransferases, in Carbohydrate-Based Drug Discovery, Wong, C.-H., Ed. Wiley-VCH, 2003. pp 781-797.

105. Dube, D. H.; Bertozzi, C. R. Metabolic Oligosaccharide Engineering as a Tool for Glycobiology. Curr. Opin. Chem. Biol. 2003, 7, 616-625.

104. Wojczyk, B. S.; Stwora-Wojczyk, M. M.; Hagen, F. K.; Striepen, B.; Hang, H. C.; Bertozzi, C. R.; Roos, D. S.; Spitalnik, S. L. cDNA Cloning and Expression of UDP-N-acetyl-D-galactosamine:Polypeptide N-Acetylgalactosaminyltransferase T1 from Toxoplasma gondii.  Mol. Biochem. Parasitol., 2003, 131, 93-107.

103. Pratt, M. R.; Leigh, C. D.; Bertozzi, C. R. Formation of 1,1-a,a-Glycosidic Bonds by Intramolecular Aglycone Delivery. A Convergent Synthesis of Trehalose. Org. Lett. 2003, 5, 3185-3188.

102. de Graffenried, C. L.; Bertozzi, C. R. Golgi Localization of Carbohydrate Sulfotransferases is a Determinant of L-Selectin Ligand Biosynthesis. J. Biol. Chem. 2003, 278, 40282-40295.

101. Song, J.; Saiz, E.; Bertozzi, C. R. Preparation of pHEMA-CP Composites with High Interfacial Adhesion via Template-Driven Mineralization. J. Eur. Ceramic Soc. 2003, 23, 2905-2919.

100. Vocadlo, D. J.; Hang, H. C.; Kim, E. J.; Hanover, J. A.; Bertozzi, C. R. A Chemical Approach for Identifying O-GlcNAc Modified Proteins in Cells. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 9116-9121.

99. Converse, S. E.; Mougous, J. M.; Leavell, M. D.; Leary, J. A.; Bertozzi, C. R.; Cox, J. S. MmpL8 is Required for Sulfolipid Biosynthesis and M. tuberculosis Virulence. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 6121-6126.

98. Pratt, M. R.; Bertozzi, C. R. Chemoselective Ligation Applied to the Synthesis of a Biantennary N-Linked Glycoform of CD52. J. Am. Chem. Soc. 2003, 125, 6149-6159.

97. Goon, S.; Schilling, B.; Tullius, M. V.; Gibson, B. W.; Bertozzi, C. R. Metabolic Incorporation of Unnatural Sialic Acids into Haemophilus ducreyi Lipooligosaccharides.  Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 3089-3094.

96. Lemieux, G. A.; de Graffenried, C. L.; Bertozzi, C. R. A Fluorogenic Dye Activated by the Staudinger Ligation. J. Am. Chem. Soc. 2003, 128, 4708-4709.

95. Luchansky, S. J.; Yarema, K. J.; Bertozzi, C. R. GlcNAc 2-Epimerase Can Serve a Catabolic Role in Sialic Acid Metabolism. J. Biol. Chem. 2003, 278, 8035-8042.

94. Song, J.; Saiz, E.; Bertozzi, C. R. A New Approach to Mineralization of Biocompatible Hydrogel Scaffolds: An Efficient Process Toward 3-Dimensional Bonelike Composites. J. Am. Chem. Soc. 2003, 125, 1236-1243.

93. Marcaurelle, L. A.; Pratt, M. R.; Bertozzi, C. R. Synthesis of Thioether-Linked analogs of the 2,3-Sialyl-TF and MECA-79 Antigens: Mucin-Type Glycopeptides Associated with Cancer and Inflammation. ChemBioChem. 2003, No. 2-3, 224-228.

92. Luchansky, S. J.; Hang, H. C.; Saxon, E.; Grunwell, J. R.; Yu, C.; Dube, D. H.; Bertozzi, C. R. Constructing Azide-Labeled Cell Surfaces Using Polysaccharide Biosynthetic Pathways. Meth. Enzymol. 2003, 362, 249-272.

91. Scherman, M. S.; Winans, K. A.; Stern, R. J.; Jones, V.; Bertozzi, C. R.; McNeil, M. R. Drug Targeting Mycobacterium tuberculosis Cell Wall Synthesis: Development of a Microtiter Plate-Based Screen for UDP-galactopyranose Mutase and Identification of an Inhibitor from a Uridine-Based Library. Antimicrobial Agents and Chemotherapy 2003, 47, 378-382.

90. Armstrong, J. I.; Verdugo, D. E.; Bertozzi, C. R. Synthesis of a Bisubstrate Analog Targeting Estrogen Sulfotransferase. J. Org. Chem. 2003, 68, 170-173.

 

2002

89. Mougous, J. D.; Leavell, M. D.; Senaratne, R. H.; Leigh, C. D.; Williams, S. J.; Riley, L. W.; Leary, J. A.; Bertozzi, C. R. Discovery of Sulfated Metabolites in Mycobacteria With a Genetic and Mass Spectrometric Approach. Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 17037-17042.

88. Saxon, E.; Luchansky, S. J.; Hang, H. C.; Yu, C.; Lee, S. C.; Bertozzi, C. R. Investigating Cellular Metabolism of Synthetic Azidosugars Using the Staudinger Ligation. J. Am. Chem. Soc. 2002, 124, 14893-14902.

87. Grunwell, J. R.; Rath, V. L.; Rasmussen, J.; Cabrilo, Z.; Bertozzi, C. R. Characterization and Mutagenesis of Gal/GlcNAc-6-O-sulfotransferases. Biochemistry 2002, 41, 15590-15600.

86. Grunwell, J. R.; Bertozzi, C. R. Carbohydrate Sulfotransferases of the GalNAc/Gal/GlcNAc6ST Family.  Biochemistry 2002, 41, 13117-13126.

85. Parak, W. J.; Gerion, D.; Zanchet, D.; Woerz, A. S.; Pellegrino, R.; Micheel, C.; Williams, S. C.; Seitz, M.; Bruehl, R. E.; Bryant, Z.; Bustamante, C.; Bertozzi, C. R.; Alivisatos, A. P. Conjugation of DNA to Silanized Colloidal Semiconductor Nanocrystalline Quantum Dots. Chem. Mater. 2002, 14, 2113-2119.

84. Pi, N.; Armstrong, J. I.; Bertozzi, C. R.; Leary, J. A. Kinetic Analysis of NodST Sulfotransferase Using an Electrospray Ionization Mass Spectrometry Assay. Biochemistry 2002, 41, 13283-13288.

83. Mougous, J. D.; Green, R. E.; Williams, S. J.; Brenner, S. E.; Bertozzi, C. R. Sulfotransferases and Sulfatases in Mycobacteria. Chem. Biol. 2002, 9, 767-776.

82. Williams, S. J.; Senaratne, R. H.; Mougous, J. D.; Riley, L. W.; Bertozzi, C. R. 5’-Adenosinephosphosulfate Lies at a Metabolic Branchpoint in Mycobacteria. J. Biol. Chem. 2002, 277, 32606-32615.

81. Verdugo, D. E.; Bertozzi, C. R. A 96-Well Dot-Blot Assay for Carbohydrate Sulfotransferases. Anal. Biochem. 2002, 307, 330-336.

80. Grogan, M. J.; Pratt, M. R.; Marcaurelle, L. A.; Bertozzi, C. R. Homogeneous Glycopeptides and Glycoproteins for Biological Investigation. Annu. Rev. Biochem. 2002, 71, 593-634.

79. Conrad, R. M.; Grogan, M. J.; Bertozzi, C. R. Stereoselective Synthesis of myo-Inositol via Ring-Closing Metathesis: A Building Block for Glycosylphosphatidylinositol (GPI) Anchor Synthesis. Org. Lett. 2002, 4, 1359-1361.

78. Charter, N; Mahal, L. K.; Koshland, D. E., Jr.; Bertozzi, C. R. Differential Effects of Unnatural Sialic Acids on the Polysialylation of NCAM and Neuronal Behavior. J. Biol. Chem. 2002, 277, 9255-9261.

77. Winans, K. A.; Bertozzi, C. R. An Inhibitor of the Human UDP-GlcNAc 4-Epimerase Identified from a Uridine-Based Library: A Strategy to Inhibit O-Linked Glycosylation. Chem. Biol. 2002, 9, 113-129.

76. Kiick, K. L.; Saxon, E.; Tirrell, D. A.; Bertozzi, C. R. Incorporation of Azides into Recombinant Proteins for Chemoselective Modification by the Staudinger Ligation. Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 19-24.

75. Cook, B. N.; Bertozzi, C. R. Chemical Approaches to the Investigation of Cellular Systems. Bioorg. Med. Chem. 2002, 10, 829-840.

74. Marcaurelle, L. A.; Bertozzi, C. R. Recent Advances in the Chemical Synthesis of Mucin-Type Glycoproteins. Glycobiology 2002, 12, R69-R77.

73. Kehoe, J. W.; Maly, D. J.; Verdugo, D. E.; Armstrong, J. I.; Cook, B. N.; Ouyang, Y.-B.; Moore, K. L.; Ellman, J. E.; Bertozzi, C. R.  Tyrosylprotein Sulfotransferase Inhibitors Generated by Combinatorial Target-Guided Ligand Assembly.  Bioorg. Med. Chem. Lett. 2002, 12, 329-332.

 

2001

72. Nauman, D. A.; Bertozzi, C. R. Determination of Kinetic Parameters for Chemoselective Reaction with Cell-Surface Ketones: A Mathematical Model for Small-Molecule Drug Delivery. Biochim. Biophys. Acta. 2001, 1568, 147-154.

71. Sampson, N. S.; Mrksich, M.; Bertozzi, C. R. Surface Molecular Recognition. Proc. Natl. Acad. Sci. U.S.A 2001, 98, 12870-12871.

70. Marcaurelle, L. A.; Shin, Y.; Goon, S.; Bertozzi, C. R. Synthesis of Oxime-linked Mucin Mimics Containing the Tumor-related TN and Sialyl TN Antigens. Org. Lett. 2001, 3, 3691-3694.

69. Mahal, L. K.; Charter, N. W.; Angata, K.; Fukuda, M.; Koshland, D. E., Jr.; Bertozzi, C. R.  A Small Molecule Modulator of Poly-a2,8-Sialic Acid Expression on Cultured Neurons and Tumor Cells. Science 2001, 294, 380-382.

68. Jacobs, C. L.; Goon, S.; Yarema, K. J.; Hinderlich, S.; Hang, H. C.; Chai, D. H.; Bertozzi, C. R. Substrate Specificity of the Sialic Acid Biosynthetic Pathway. Biochemistry 2001, 40, 12864-12874.

67. Saxon, E.; Bertozzi, C. R. Chemical and Biological Strategies for Engineering Cell Surface Glycosylation. Ann. Rev. Cell Dev. Biol. 2001, 17, 1-23.

66. Schilling, B.; Goon, S.; Samuels, N. M.; Gaucher, S. P.; Leary, J. A.; Bertozzi, C. R.; Gibson, B. W. Biosynthesis of Sialylated Lipooligosaccharides in Haemophilus ducreyi is Dependent on Exogenous Sialic Acid and not Mannosamine. Biochemistry 2001, 40, 12666-12677.

65. Bruehl, R. E.; Dasgupta, F.; Katsumoto, T. R.; Tan, J. H.; Bertozzi, C. R.; Spevak, W.; Ahn, D. J.; Rosen, S. D.; Nagy, J. O. Polymerized Liposome Assemblies: Bifunctional Macromolecular Selectin Inhibitors Mimicking Physiological Selectin Ligands. Biochemistry 2001, 40, 5964-5974.

64. Armstrong, J. I.; Ge, X.; Verdugo, D. E.; Winans, K. A.; Leary, J. A.; Bertozzi, C. R. A Library Approach to the Generation of Bisubstrate Analog Sulfotransferase Inhibitors. Org. Lett. 2001, 3, 2657-2660.

63. Verdugo, D. E.; Cancilla, M. T.; Ge, X.; Gray, N. S.; Chang, Y.-T.; Schultz, P. G.; Negishi, M.; Leary, J. A.; Bertozzi, C. R. Discovery of Estrogen Sulfotransferase Inhibitors from a Purine Library Screen. J. Med. Chem., 2001, 44, 2683-2686.

62. Hang, H. C.; Bertozzi, C. R. Chemoselective Approaches to Glycoprotein Engineering. Accounts Chem. Res. 2001, 34, 727-736.

61. Groves, J. T.; Mahal, L. K.; Bertozzi, C. R. Control of Cell Adhesion and Growth with Micropatterned Supported Lipid Membranes. Langmuir 2001, 17, 5129-5133.

60. Yarema, K. J.; Goon, S.; Bertozzi, C. R. Metabolic Selection of Glycosylation Defects in Human Cells. Nature Biotechnol. 2001, 19, 553-558.

59. Yarema, K. J.; Bertozzi, C. R. Characterizing Glycosylation Pathways. Genome Biology 2001, 2, 0004.1-0004.10.

58. Lemieux, G. A.; Bertozzi, C. R. Modulating Cell Surface Immunoreactivity by Metabolic Induction of Unnatural Carbohydrate Antigens. Chem. Biol. 2001, 8, 265-275.

57. Bertozzi, C. R.; Kiessling, L. L. Chemical Glycobiology. Science 2001, 291, 2357-2364.

56. Marcaurelle, L. A.; Bertozzi, C. R. Chemoselective Elaboration of O-Linked Glycopeptide Mimetics by Alkylation of 3-ThioGalNAc. J. Am. Chem. Soc. 2001, 123, 1587-1595.

55. Marcaurelle, L. A.; Mizoue, L. S.; Wilken, J.; Oldham, L.; Kent, S. B. H.; Handel, T. M.; Bertozzi, C. R.  Chemical Synthesis of Lymphotactin, a Glycosylated Chemokine with a C-terminal Mucin-like Domain.  Chem. Eur. J. 2001, 7, 1129-1132.

54. Hang, H. C., Bertozzi, C. R.  Ketone Isosteres of 2-N-Acetamidosugars as Substrates for Metabolic Cell Surface Engineering. J. Am. Chem. Soc. 2001, 123, 1242-1243.

53. Bowman, K. G.; Cook, B. N.; de Graffenried, C. L.; Bertozzi, C. R.  Biosynthesis of L-selectin Ligands: Sulfation of Sialyl Lewis x-Related Oligosaccharides by a Family of GlcNAc-6-Sulfotransferases. Biochemistry 2001, 40, 5382-5391.

 

2000

52. Bruehl, R. E.; Bertozzi, C. R.; Rosen, S. D.  Minimal sulfated carbohydrates for recognition by L-selectin and the MECA-79 antibody.  J. Biol. Chem. 2000, 275, 32642-32648.

51. Bhakta, S.; Bartes, A.; Bowman, K. G.; Kao, W.-M.; Polsky, I.; Lee, J. K.; Cook, B. N.; Bruehl, R.; Rosen, S. D.; Bertozzi, C. R.; Hemmerich, S.  Sulfation of N-Acetylglucosamine by Chondroitin 6-Sulfotransferase 2 (GST5).  J. Biol. Chem. 2000, 275, 40226-40234.

50. Macmillan, D.; Bertozzi, C. R.  New Directions in Glycoprotein Engineering.  Tetrahedron 2000, 56, 9515-9525.

49. Cook, B. N.; Bhakta, S.; Biegel, T.; Bowman, K. G.; Armstrong, J. I.; Hemmerich, S.; Bertozzi, C. R.  Differential Carbohydrate Recognition of Two GlcNAc-6-Sulfotransferases with Possible Roles in L-Selectin Ligand Biosynthesis.  J. Am. Chem. Soc. 2000, 122, 8612-8622.

48. Armstrong, J. I.; Bertozzi, C. R.  Sulfotransferases as Targets for Therapeutic Intervention.  Curr. Opin. Drug Disc. Dev. 2000, 3, 502-515.

47. Charter, N. W.; Mahal, L. K.; Koshland, D. E., Jr.; Bertozzi, C. R. Biosynthetic Incorporation of Unnatural Sialic Acids into Polysialic Acid on Neural Cells. Glycobiology, 2000, 10, 1-8.

46. Jacobs, C. J.; Yarema, K. J.; Mahal, L. K.; Nauman, D. A.; Charters, N.; Bertozzi, C. R. Metabolic Labeling of Glycoproteins with Chemical Tags through Unnatural Sialic Acid Biosynthesis. Meth. Enzymol. 2000, 327, 260-275.

45. Saxon, E.; Armstrong, J. I.; Bertozzi, C. R. A "Traceless" Staudinger Ligation for the Chemoselective Synthesis of Amide Bonds. Org. Lett. 2000, 2, 2141-2143.

44. Saxon, E.; Bertozzi, C. R. Cell Surface Engineering by a Modified Staudinger Reaction. Science 2000, 287, 2007-2010.

43. Armstrong, J. I.; Portley, A. R.; Chang, Y.-T.; Nierengarten, D. M.; Cook, B. N.; Bowman, K. G.; Bishop, A.; Gray, N. S.; Shokat, K. M.; Schultz, P. G.; Bertozzi, C. R. Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library. Angew. Chem., Int. Ed. 2000, 39, 1303-1306.

42. Kehoe, J. W.; Bertozzi, C. R. Tyrosine Sulfation: A Modulator of Extracellular Protein-Protein Interactions. Chem. Biol. 2000, 7, R57-R61.

 

1999

41. Shin, Y.; Winans, K. A.; Backes, B. J.; Kent, S. B. H.; Ellman, J. A.; Bertozzi, C. R. Fmoc-Based Synthesis of Peptide-aThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation. J. Am. Chem. Soc. 1999, 121, 11684-11689.

40. Mahal, L. K.; Yarema, K. J.; Lemieux, G. A.; Bertozzi, C. R. Chemical Approaches to Glycobiology: Engineering Cell Surface Sialic Acids for Tumor Targeting, in Sialobiology and Other Novel Forms of Glycosylation, Inoue, Y.; Lee, Y. C.; Troy, F. A., III, eds. Gakushin Publishing Company: Osaka, 1999, pp. 237-280.

39. Winans, K. A.; King, D. A.; Rao, V.; Bertozzi, C. R. A Chemically Synthesized Version of the Insect Antibacterial Glycopeptide, Diptericin, Disrupts Bacterial Membrane Integrity. Biochemistry 1999, 38, 11700-11710.

38. Lee, J. H.; Baker, T. J.; Mahal, L. K.; Zabner, J.; Bertozzi, C. R.; Wiemer, D. F.; Welsh, M. J. Engineering Novel Cell Surface Receptors for Virus-Mediated Gene Transfer. J. Biol. Chem. 1999, 274, 21878-21884.

37. Lemieux, G. A.; Yarema, K. J.; Jacobs, C. L.; Bertozzi, C. R. Exploiting Differences in Sialoside Expression for Selective Targeting of MRI Contrast Reagents. J. Am. Chem. Soc. 1999, 121, 4278-4279.

36. Marcaurelle, L. A.; Bertozzi, C. R. New Directions in the Synthesis of Glycopeptide Mimetics. Chem. Eur. J. 1999, 5, 1384-1390.

35. Chen, Q.; Zhang, D.; Somorjai, G.; Bertozzi, C. R. Probing the Surface Structural Rearrangement of Hydrogels by Sum-Frequency Generation Spectroscopy.  J. Am. Chem. Soc. 1999, 121, 446-447.

34. Bowman, K. G.; Bertozzi, C. R. Carbohydrate Sulfotransferases: Mediators of Extracellular Communication. Chem. Biol.  1999, 6, R9-R22.

 

1998

33. Winans, K. A.; Bertozzi, C. R. Inner Space Exploration: The Chemical Biologist's Guide to the Cell. Chem. Biol.  1998, 5, R313-R315.

32. Yarema, K. J.; Mahal, L. K.; Bruehl, R.; Rodriguez, E. C.; Bertozzi, C. R. Metabolic Delivery of Ketone Groups to Sialic Acid Residues. Application to Cell Surface Glycoform Engineering. J. Biol. Chem. 1998, 273, 31168-31179.

31. Marcaurelle, L. A.; Rodriguez, E. C.; Bertozzi, C. R. Synthesis of an Oxime-Linked Neoglycopeptide with Glycosylation-Dependent Activity Similar to its Native Counterpart. Tetrahedron Lett. 1998, 39, 8417-8420.

30. Rodriguez, E. C.; Marcaurelle, L. A.; Bertozzi, C. R. Aminooxy, Hydrazide and Thiosemicarbazide-Functionalized Saccharides: Versatile Reagents for Glycoconjugate Synthesis. J. Org. Chem. 1998, 63, 7134-7135.

29. Marcaurelle, L. A.; Bertozzi, C. R. Direct Incorporation of Unprotected Ketone Groups into Peptides During Solid-Phase Synthesis: Application to the One-Step Synthesis of Peptides with Two Different Biophysical Probes for FRET. Tetrahedron Lett. 1998, 39, 7279-7282.

28. Bowman, K. G.; Hemmerich, S.; Bhakta, S.; Singer, M. S.; Rosen, S. D.; Bertozzi, C. R. Identification of an N-Acetylglucosamine-6-O-Sulfotransferase Activity Restricted to Lymphoid Tissue: An Enzyme with a Possible Role in Lymphocyte Homing. Chem. Biol. 1998, 5, 447-460.

27. Lemieux, G. A. ; Bertozzi, C. R. Chemoselective Ligation Reactions with Proteins, Oligosaccharides and Cells. Trends Biotech. 1998, 16, 506-513.

26. Yarema, K. J.; Bertozzi, C. R. Chemical Approaches to Glycobiology and Emerging Carbohydrate-Based Therapeutic Agents. Curr. Opin. Chem. Biol. 1998, 2, 49-61.

 

1997

25. Rodriguez, E. C.; Winans, K. A.; King, D. S.; Bertozzi, C. R. A Strategy for the Chemoselective Synthesis of O-Linked Glycopeptides with Native Sugar-Peptide Linkages. J. Am. Chem. Soc. 1997, 119, 9905-9906.

24. Mahal, L. K.; Bertozzi, C. R. Engineered Cell Surfaces:  Fertile Ground for Molecular Landscaping. Chem. Biol. 1997, 4, 415-422.

23. Mahal, L. K.; Yarema, K. J.; Bertozzi, C. R. Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis. Science 1997, 276, 1125-1128.

22. Bertozzi, C. R.; Singer, M. S.; Rosen, S. D. An ELISA for Selectin Inhibitors Based on Binding to a Physiological Ligand. J. Immunol. Meth. 1997, 203, 157-165.

 

1996

21. Sanders, W. J.; Katsumoto, T. R.; Bertozzi, C. R.; Rosen, S. D.; Kiessling, L. L.  L-Selectin-Carbohydrate Interactions: An Investigation into the Relevant Modifications of the Lewis x Trisaccharide. Biochemistry 1996, 35, 14862-14867.

20. Roe, B. A.; Boojamra, D. G.; Griggs, J.; Bertozzi, C. R. Synthesis of beta-C-Glycosides of N-acetylglucosamine via Keck Allylation Directed by Neighboring Phthalimide Groups. J. Org. Chem. 1996, 61, 6442-6445.

19. Manning, D. D.; Bertozzi, C. R.; Rosen, S. D.; Kiessling, L. L. Tin Mediated Phosphorylation:  Synthesis and Selectin Binding of a Phospho Lewis a Analog. Tetrahedron Lett. 1996, 37, 1953-1956.

18. Rosen, S. D.; Bertozzi, C. R. Leukocyte Adhesion: Two Selectins Converge on Sulphate. Current Biol. 1996, 6, 261-264.

17. Kobertz, W. R.; Bertozzi, C. R.; Bednarski, M. D. C-Glycosyl Aldehydes: Synthons for C-linked Disaccharides. J. Org. Chem. 1996, 61, 1894-1897.

16. Bertozzi, C. R.; Bednarski, M. D. "Synthesis of C-Glycosides: Stable Mimics of O-Glycosidic Linkages" in Modern Methods in Carbohydrate Synthesis, Khan, S. H.; O'Neill, R. A., eds. Harwood Academic Publishers GmbH: Amsterdam, 1996, pp 316-351.

 

1990-1995

15. Bertozzi, C. R. Cracking the Carbohydrate Code for Selectin Recognition. Chem. Biol.  1995, 2, 703-708.

14. Bertozzi, C. R.; Fukuda, S.; Rosen, S. D. Sulfated Disaccharide Inhibitors of L-Selectin: Deriving Structural Leads from a Physiological Selectin Ligand. Biochemistry  1995, 34, 14271-14278.

13. Manning, D. D.; Bertozzi, C. R.; Pohl, N. L.; Rosen, S. D.; Kiessling, L. L. Selectin-Saccharide Interactions: Revealing Structure-Activity Relationships with Total Synthesis. J. Org. Chem. 1995, 60, 6254-6255.

12. Rosen, S. D.; Bertozzi, C. R. The Selectins and Their Ligands. Curr. Opin. Cell Biol. 1994, 6, 663-673.

11. Hemmerich, S.; Bertozzi, C. R.; Leffler, H.; Rosen, S. D. Identification of the Sulfated Monosaccharides of GlyCAM-1, an Endothelial-Derived Ligand for L-Selectin.  Biochemistry  1994, 33, 4820-4829.

10. Grabowski, J. J.; Bertozzi, C. R.; Jacobsen, J. R.; Jain, A.; Marzluff, E. M.; Suh, A. Y. Fluorescence Probes in Biochemistry: An Examination of the Non-Fluorescent Behavior of Dansylamide by Photoacoustic Calorimetry. Analytical Biochem. 1992, 207, 214-226.

9. Bertozzi, C. R.; Cook, D. G.; Kobertz, W. R.; Gonzalez-Scarano, F.; Bednarski, M. D. Carbon-Linked Galactosphingolipid Analogs Bind Specifically to HIV-1 gp120. J. Am. Chem. Soc. 1992, 114, 10639-10641.

8. Bertozzi, C. R.; Hoeprich, P. D., Jr.; Bednarski, M. D. Synthesis of Carbon-Linked Glycopeptides as Stable Glycopeptide Models. J. Org. Chem. 1992, 57, 6092-6094.

7. Bertozzi, C. R.; Bednarski, M. D. The Synthesis of 2-Azido C-Glycosyl Sugars. Tetrahedron Lett. 1992, 33, 3109-3112.

6. Bertozzi, C. R.; Bednarski, M. D. A Receptor-Mediated Immune Response Using Synthetic Glycoconjugates. J. Am. Chem. Soc. 1992, 114, 5543-5546.

5. Bertozzi, C. R.; Bednarski, M. D. Antibody Targeting to Bacterial Cells Using Receptor-Specific Ligands. J. Am. Chem. Soc. 1992, 114, 2242-2245.

4. Kobertz, W. R.; Bertozzi, C. R.; Bednarski, M. D. An Efficient Method for the Synthesis of alpha- and beta-C-Glycosyl Aldehydes. Tetrahedron Lett. 1992, 33, 737-740.

3. Bertozzi, C. R.; Bednarski, M. D. C-Glycosyl Compounds Bind to Receptors on the Surface of Escherichia coli and can Target Proteins to the Organism. Carbohydrate Res. 1992, 223, 243-253.

2. Bertozzi, C. R.; Bednarski, M. D. The Synthesis of Heterobifunctional Linkers for the Conjugation of Ligands to Molecular Probes. J. Org. Chem.  1991, 56, 4326-4329.

1. Chidsey, C. E. D.; Bertozzi, C. R.; Putvinski, T. M.; Mujsce, A. M. Coadsorption of Ferrocene-Terminated and Unsubstituted Alkanethiols on Gold: Electroactive Self-Assembled Monolayers. J. Am. Chem. Soc.  1990, 112, 4301-4306.

Books

Wang, P. G.; Bertozzi, C. R., Eds. Glycochemistry. Principles, Synthesis and Applications. Marcel Dekker, Inc.: New York, 2001.

Varki, A.; Cummings, R. D.; Esko, J. D.; Freeze, H. H.; Stanley, P.; Bertozzi, C. R.; Hart, G. W.; Etzler, M. E., Eds. Essentials of Glycobiology, Second Edition. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, 2009.

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