Sam MaurerGraduate Student, Ph.D. ProgramMIT, Research Interest: Surface Kinetic Mechanisms of Cellulose Destruction |
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Research Summary: Surface Kinetic Mechanisms of Enzymatic Cellulose
Deconstruction The
rate-determining step in the biological decomposition of lignocellulosic
feedstocks is the enzymatic cleavage of lignocellulose found in plant cell
walls to simple sugars. Currently, this process is accomplished through the
reaction of solid lignocellulose crystals suspended in an aqueous solution
containing various enzymes and cellulaseproducing bacteria. The rate of
lignocellulose deconstruction is governed by surface interactions between crystalline
lignocellulose and aqueous cellulase. Rate data currently available on
cellulose deconstruction kinetics has been obtained through batch studies;
little is known about the molecular events that trigger the release of
cellobiose from the surface of crystalline lignocellulose. We seek to
quantify these surface interactions through flow ellipsometry, quartz crystal
microbalance, and optical waveguide light spectroscopy, and ultimately hope
to create a mechanistic model of cellulase kinetics at a cellulose surface.
Click to see almost all of Sam’s Research to date: Sam's Totally Awesome Poster (Sam made this poster in two days and therefore thinks that he has already done enough work for the year 2008.) |
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