CHANG LAB PUBLICATIONS PHOTOS GROUP MEETINGS CONTACT LINKS
RESEARCH PUBLICATIONS PEOPLE PHOTOS GROUP MEETINGS CONTACT LINKS

RESEARCH

Click on a research area below to read more

Transition Metal Signaling Bioinorganic


Activity-based Sensing ABS


Metals in Neurobiology Metals


Artificial Photosynthesis Artificial


Drawing from core disciplines of inorganic chemistry, organic chemistry, and molecular biology, students in the laboratory receive broad-based, fundamental training in experimental techniques ranging from synthetic chemistry to spectroscopy and electrochemistry to protein biochemistry to cell and animal work. Representative skill sets and expertise in the group are given below. Students are encouraged to take multiple approaches to ask and answer new scientific questions.

Chemical Biology, Bioinorganic Chemistry, and Organic Chemistry Students
Synthetic chemistry: Design of activity-based sensing (ABS) probes for imaging, proteomics, drug discovery, and drug delivery
Spectroscopy and characterization: Fluorescence, HPLC, LC/GC-MS assays
Imaging: Confocal Microscopy, flow cytometry, bioluminescence, MRI, PET
Chemoproteomics: Activity-based protein profiling, metabolomics, ICP-MS, Nano-SIMS imaging
Biochemistry: Enzymology, protein engineering, bioconjugation, antibody labeling, optogenetics
Molecular biology: Cloning, transfections, RNAi, PCR, CRISPR
Cell culture: Mammalian cell lines, primary neurons, bacteria
Animal work: Zebrafish, mouse models
Inorganic and Materials Chemistry Students
Ligand synthesis: Design of first- and second-sphere coordination environments
Inorganic and materials synthesis: Glovebox and Schlenk-line preparation of air- and moisture-sensitive transition metal complexes, electrodeposition of films, supramolecular self-assembly
Molecular characterization: X-ray crystallography, NMR, mass spectrometry
Materials characterization: XPS, SEM, DLS, EDX, X-ray powder diffraction
Spectroscopy: UV-Vis, IR, Mössbauer, X-ray absorption, EPR, SQUID
Electrochemistry: Cyclic voltammetry, bulk electrolysis, rotating ring-disk electrochemistry, spectroelectrochemistry
Photochemistry: Steady-state photocatalysis, inline GC-MS measurements
Mechanistic studies: In situ UV-Vis, react-IR, NMR, and electrochemical assays


BACK TO TOP



Updated July 17 2017