Publications


  1. Que, E. L.; Domaille, D. W.; Chang, C. J. "Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging", Chem. Rev. 2008, ASAP. [pdf]


  2. Domaille, D. W.; Que, E. L.; Chang, C. J. "Synthetic Fluorescent Sensors for Studying the Cell Biology of Metals", Nat. Chem. Biol. 2008, 4, 168-175. [pdf]


  3. Srikun, D.; Miller, E. W.; Domaille, D. W.; Chang, C. J. "An ICT-Based Approach to Ratiometric Fluorescence Imaging of Hydrogen Peroxide Produced in Living Cells", J. Am. Chem. Soc. 2008, 130, 4596-4597. [pdf]




  4. Harman, W. H.; Chang, C. J. "N2O Activation and Oxidation Reactivity from a Non-Heme Iron Pyrrole Platform", J. Am. Chem. Soc. 2007, 129, 15128-15129. [pdf]




  5. Miller, E. W.; Chang, C. J. "Fluorescent probes for nitric oxide and hydrogen peroxide in cell signaling" Curr. Opin. Chem. Biol. 2007, 11, 620-625. [pdf]


  6. Albers, A. E.; Rawls, K. A.; Chang, C. J "Activity-based fluorescent reporters for monoamine oxidases in living cells", Chem. Commun. 2007, 4647-4649. [pdf]




  7. Yoon, S.; Miller, E. W.; He, Q.; Do, P. H.; Chang, C. J "A Bright and Specific Fluorescent Sensor for Mercury in Water, Cells, and Tissue", Angew. Chem. Int. Ed. 2007, 46, 6658-6661. [pdf]




  8. Miller, E. W.; Tulyathan, O.; Isacoff, E. Y.; Chang, C. J. "Molecular imaging of hydrogen peroxide produced for cell signaling", Nat. Chem. Biol. 2007, 3, 263-267. [pdf] [C & E News]




  9. Miller, E. W.; Bian, S. X.; Chang, C. J. "A Fluorescent Sensor for Imaging Reversible Redox Cycles in Living Cells", J. Am. Chem. Soc. 2007, 129, 3458-3459. [pdf]




  10. Que, E. L.; Chang, C. J. "A Smart Magnetic Resonance Contrast Agent for Selective Copper Sensing", J. Am. Chem. Soc. 2006, 128, 15942-15943. [pdf]




  11. Miller, E. W.; Zeng, L.; Domaille, D. W.; Chang, C. J. "Preparation and Use of Coppersensor-1, a Synthetic Fluorophore for Live-Cell Copper Imaging", Nature Protocols 2006, 1, 824-827. [pdf]


  12. Albers, A. E.; Okreglak, V. S.; Chang, C. J. "A FRET-Based Approach to Ratiometric Fluorescence Detection of Hydrogen Peroxide", J. Am. Chem. Soc. 2006, 128, 9640-9641. [pdf]




  13. He, Q.; Miller, E. W.; Wong, A. P.; Chang, C. J. "A Selective Fluorescent Sensor for Detecting Lead in Living Cells", J. Am. Chem. Soc. 2006, 128, 9316-9317. [pdf]




  14. Zeng, L.; Miller, E. W.; Pralle, A.; Isacoff, E. Y.; Chang, C. J. "A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells", J. Am. Chem. Soc. 2006, 128, 10-11. [pdf]




  15. Miller, E. W.; Albers, A. E.; Pralle, A.; Isacoff, E. Y.; Chang, C. J. "Boronate-Based Fluorescent Probes for Imaging Cellular Hydrogen Peroxide", J. Am. Chem. Soc. 2005, 127, 16652-16659. [pdf]




  16. Yoon, S.; Albers, A. E.; Wong, A. P.; Chang, C. J. "Screening Mercury Levels in Fish with a Selective Fluorescent Chemosensor", J. Am. Chem. Soc. 2005, 127, 16030-16031. [pdf] [C & E News]




  17. Chang, M. C. Y.; Pralle, A.; Isacoff, E. Y.; Chang, C. J. "A Selective, Cell-Permeable Optical Probe for Hydrogen Peroxide in Living Cells", J. Am. Chem. Soc. 2004, 126, 15392-15393. [pdf] [C & E News]




  18. Chang, C. J.; Lippard, S. J. "Zinc Metalloneurochemistry: Physiology, Pathology, and Probes", In Metal Ions in Life Science: Neurodegenerative Diseases and Metal Ions. 2006, Vol. 1, pp. 321-370.

  19. Giblin, L. J.; Chang, C. J.; Bentley, A. F.; Frederickson, C.; Lippard, S. J.; Frederickson, C. J. "Zinc-Secreting Paneth Cells Studied by ZP Fluorescence", J. Histochem. Cytochem. 2006, 54, 311-316.

  20. Chang, C. J.; Nolan, E.M.; Jaworski, J.; Okamoto, K.; Hayashi, T.; Sheng, M.; Lippard, S.J. "ZP8, an Improved Neuronal Zinc Sensor of the ZP Family: Application to Imaging Zinc in Hippocampal Slices with Two-Photon Microscopy", Inorg. Chem. 2004, 43, 6774-6779.

  21. Chang, C. J.; Loh, Z.-H.; Shi, C.; Anson, F.C. Nocera, D. G. "Targeted Proton Delivery in the Catalyzed Reduction of Oxygen to Water by Bimetallic Pacman Porphyrins", J. Am. Chem. Soc. 2004, 126, 10013-10020.

  22. Chang, C. J.; Chang, M.C.Y.; Damrauer, N.H.; Nocera, D.G. "Proton-Coupled Electron Transfer. A Unifying Mechanism for Biological Charge Transport, Amino Acid Radical Initiation and Propagation, and Bond Making/Breaking Reactions of Water and Oxygen", Biochim. Biophys. Acta 2004, 1655, 13-28.

  23. Chang, C. J.; Nolan, E.M.; Jaworski, J.; Burdette, S.C.; Sheng, M.; Lippard, S.J. "Bright Fluorescent Chemosensor Platforms for Imaging Endogenous Pools of Neuronal Zinc", Chem. Biol. 2004, 11, 203-210.

  24. Chang, C. J.; Jaworski, J.; Nolan, E.M.; Sheng, M.; Lippard, S.J. "A Tautomeric Zinc Sensor for Ratiometric Fluorescence Imaging: Application to Nitric Oxide-Induced Release of Intracellular Zinc", Proc. Natl. Acad. Sci. USA 2004, 101, 1129-1134.

  25. Hodgkiss, J.M.; Chang, C. J.; Pistorio, B.J.; Nocera, D. G. "Transient Absorption Studies of the Pacman Effect in Spring-Loaded Diiron(III) mu-Oxo Bisporphyrins", Inorg. Chem. 2003, 42, 8270-8277.

  26. Chang, C. J.; Loh, Z.-H.; Deng, Y.; Nocera, D. G. "The Pacman Effect: A Supramolecular Strategy for Controlling the Excited-State Dynamics of Pillared Cofacial Bisporphyrins", Inorg. Chem. 2003, 42, 8262-8269.

  27. Chng, L.-L.; Chang, C. J.; Nocera, D. G. "Meso-Tetraaryl Cofacial Bisporphyrins Delivered by Suzuki Cross-Coupling", J. Org. Chem. 2003, 68, 4075-4078.

  28. Chng, L.-L.; Chang, C. J.; Nocera, D. G. "Catalytic O-O Activation Chemistry Mediated by Iron Hangman Porphyrins with a Wide Range of Proton-Donating Abilities", Org. Lett. 2003, 5, 2421-2424.

  29. Chang, C. J.; Chng, L.-L.; Nocera, D. G. "Proton-Coupled O-O Activation on a Redox Platform Bearing a Hydrogen-Bonded Scaffold", J. Am. Chem. Soc. 2003, 125, 1866-1876.

  30. Loh, Z.-H.; Miller, S. E.; Chang, C. J.; Carpenter, S. D.; Nocera, D. G. "Excited State Dynamics of Cofacial Pacman Porphyrins", J. Phys. Chem. A 2002, 106, 11700-11708.

  31. Pistorio, B. J.; Chang, C. J.; Nocera, D. G. "A Phototriggered Molecular Spring for Aerobic Catalytic Oxidation Reactions", J. Am. Chem. Soc. 2002, 124, 7884-7885.

  32. Chang, C. J.; Baker, E. A.; Pistorio, B. J.; Deng, Y.; Loh, Z.-H.; Miller, S. E.; Carpenter, S. D.; Nocera, D. G. "Structural, Spectroscopic, and Reactivity Comparison of Xanthene- and Dibenzofuran-Bridged Cofacial Bisporphyrins", Inorg. Chem. 2002, 41, 3102-3109.

  33. Chang, C. J.; Deng, Y.; Lee, G.-H.; Peng, S.-M.; Yeh, C.-Y.; Nocera, D. G. "A Convergent Synthetic Approach Using Sterically Demanding Aryl-Dipyrrylmethanes for Tuning the Pocket Sizes of Cofacial Bisporphyrins", Inorg. Chem. 2002, 41, 3008-3016.

  34. Chang, C. J.; Yeh, C.-Y.; Nocera, D. G. "Porphyrins Bearing Functionalized Xanthene Spacers", J. Org. Chem. 2002, 67, 1403-1406.

  35. Chang, C. J.; Brown, J. D. K.; Chang, M. C. Y.; Baker, E. A.; Nocera, D. G. "Electron Transfer in Hydrogen-Bonded Donor-Acceptor Supramolecules", In Electron Transfer in Chemistry, V. Balzani Ed., Wiley-VCH, Weinheim, Germany, 2001, Vol. 3.2.4., p 409-461.

  36. Yeh, C.-Y.; Chang, C. J.; Nocera, D. G. "'Hangman' Porphyrins for the Assembly of a Model Heme Water Channel", J. Am. Chem. Soc. 2001, 123, 1513-1514.

  37. Chang, C. J.; Deng, Y.; Shi, C.; Chang, C. K.; Anson, F. C.; Nocera, D. G. "Electrocatalytic Four-Electron Reduction of Oxygen to Water by a Highly Flexible Cofacial Cobalt Bisporphyrin", Chem. Commun. 2000, 1355-1356.

  38. Chang, C. J.; Deng, Y.; Heyduk, A. F.; Chang, C. K.; Nocera, D. G. "Xanthene-Bridged Cofacial Bisporphyrins", Inorg. Chem. 2000, 39, 959-966.

  39. Deng, Y.; Chang, C. J.; Nocera, D. G. "Direct Observation of the 'Pac-Man' Effect from Dibenzofuran-Bridged Cofacial Bisporphyrins" J. Am. Chem. Soc. 2000, 122, 410-411.

  40. Chang, C. J.; Connick, W. B.; Low, D. W.; Day, M. W.; Gray, H. B. "Electronic Structures of Nitridomanganese(V) Complexes", Inorg. Chem. 1998, 37, 3107-3110.

  41. Chang, C. J.; Labinger, J. A.; Gray, H. B. "Aerobic Epoxidation of Olefins Catalyzed by Electronegative Vanadyl Salen Complexes", Inorg. Chem. 1997, 36, 5927-5930.

  42. Chang, C. J.; Low, D. W.; Gray, H. B. "Reversible Nitrogen Atom Transfer between Nitridomanganese(V) and Manganese(III) Schiff-Base Complexes", Inorg. Chem. 1997, 36, 270-271.




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