Publications

222. Beavers, W. N.; DuMont, A. L.; Monteith, A. J.; Maloney, K. N.; Tallman, K. A.; Weiss, A.; Christian, A. H.; Toste, F. D.; Chang, C. J.; Porter, N. A.; Torres, V. J.; Skaar, E. P. "Staphylococcus aureus peptide methionine sulfoxide reductases protect from human whole blood killing", Infect. Immun. 2021, 89, IAI-00146. [html]



221. Jia, S.; Chang, C. J. "A microtubule-localizing activity-based sensing fluorescent probe for imaging hydrogen peroxide in living cells", Bioorg. Med. Chem. Lett. 2021, 48, 128252. [html] [pdf]



220. Smith, P. T.; Benke, B. P.; An, L.; Kim, Y.; Kim, K.; Chang, C. J. "A Supramolecular Porous Organic Cage Platform Promotes Electrochemical Hydrogen Evolution from Water Catalyzed by Cobalt Porphyrins", ChemElectroChem 2021, 8, 1653–1657. [html] [pdf]



219. Wuttig, A.; Derrick, J. S.; Loipersberger, M.; Snider, A.; Head-Gordon, M.; Chang, C. J.; Toste, D. "Controlled Single-Electron Transfer via Metal−Ligand Cooperativity Drives Divergent Nickel-Electrocatalyzed Radical Pathways", J. Am. Chem. Soc. 2021. [html] [pdf]



218. Iwashita, H.; Castillo, E.; Messina, M. S.; Swanson, R.A.; Chang, C. J. "A tandem activity-based sensing and labeling strategy enables imaging of transcellular hydrogen peroxide signaling", PNAS 2021, 118, e2018513118. [html] [pdf]



217. Kim J. H.; Matsubara T.; Lee J.; Fenollar-Ferrer C.; Han K.; Kim D.; Jia S.; Chang C. J.; Yang H.; Nagano T.; Krausz K.W. "Lysosomal SLC46A3 modulates hepatic cytosolic copper homeostasis", Nat. Commun. 2021, 12, 1–12. [html] [pdf]



216. Wang, Z.; Detomasi, T. C.; Chang, C. J. "A dual-fluorophore sensor approach for ratiometric fluorescence imaging of potassium in living cells", Chem. Sci. 2021, 12, 1720-1729. [html] [pdf]



215. Mao, Y.; Loipersberger, M.; Kron, K. J.; Derrick, J. S.; Chang, C. J.; Sharada, S. M.; Head-Gordon, M. "Consistent inclusion of continuum solvation in energy decomposition analysis: theory and application to molecular CO2 reduction catalysts", Chem. Sci. 2021, 12, 1398–1414. [html] [pdf]



214. Shen, X.; Wang, R.; Kim, M. J.; Hu, Q.; Hsu, C.; Yao, J.; Klages-Mundt, N.; Tian, Y. Lynn, E.; Brewer, T. F.; Zhang, Y.; Arun, B.; Gan, B.; Andreeff, M.; Takeda, S.; Chen, J.; Park, J.; Shi, X.; Chang, C. J.; Jung, S. Y.; Qin, J.; Li, L. "A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia", Mol. Cell 2020. 80, 1013-1024. [html] [pdf]



213. Derrick, J. S., Loipersberger, M.; Chatterjee, R.; Iovan, D. A.; Smith, P. T.; Chakarawet, K.; Yano, J.; Long, J. R.; Head-Gordon, M.; Chang, C. J. "Metal–Ligand Cooperativity via Exchange Coupling Promotes Iron- Catalyzed Electrochemical CO2 Reduction at Low Overpotentials", J. Am. Chem. Soc. 2020, 142, 20489–20501. [html] [pdf]



212. Amor, M.; Ceballos, A.; Wan, J.; Simon, C. P.; Aron, A. T.; Chang, C. J.; Hellman, F.; Komeili, A. "Magnetotactic Bacteria Accumulate a Large Pool of Iron Distinct from Their Magnetite Crystals", Appl. Environ. Microbiol. 2020, 86, e01278–20. [html] [pdf]


211. Zhao, Y.; Wei, L.; Tagmount, A.; Loguinov, A.; Sobh, A.; Hubbard, A.; McHale, C. M.; Chang, C. J.; Vulpe, C. D.; Zhang, L. "Applying Genome-wide CRISPR to Identify Known and Novel Genes and Pathways that Modulate Formaldehyde Toxicity", Chemosphere 2020, 128701. [html]


210. Toh, J. D. W.; Crossley, S. W. M.; Bruemmer, K. J.; Ge, E. J.; He, D.; Iovan, D. A.; Chang, C. J. "Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates", PNAS 2020, 117, 25284-25292. [html] [pdf]


209. Morstein, J.; Höfler, D.; Ueno, K.; Jurss, J. W.; Walvoord, R. R.; Bruemmer, K. J.; Rezgui, S. P.; Brewer, T. F.; Saitoe, M.; Michel, B. W.; Chang, C. J. "Ligand-Directed Approach to Activity-Based Sensing: Developing Palladacycle Fluorescent Probes That Enable Endogenous Carbon Monoxide Detection", J. Am. Chem. Soc. 2020, 142, 15917–15930. [html] [pdf]




208. Lee, S.; Chung, C. Y.-S.; Liu, P., Craciun, L; Nishikawa, Y.; Bruemmer, K. J.; Hamachi, I.; Saijo, K.; Miller, E. W.; Chang, C. J. "Activity-Based Sensing with a Metal-Directed Acyl Imidazole Strategy Reveals Cell Type-Dependent Pools of Labile Brain Copper", J. Am. Chem. Soc. 2020, 142, 14993–15003. [html] [pdf]




207. Bruemmer, K. J.; Crossley, S. W. M.; Chang, C. J. "Activity-Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond", Angew. Chem. Int. Ed. 2020, 59, 13734–13762. [html] [pdf]




206. Proppe, A. H.; Li, Y. C.; Aspuru-Guzik, A.; Berlinguette, C. P.; Chang, C. J.; Cogdell, R.; Doyle, A. G.; Flick, J.; Gabor, N. M.; van Grondelle, R.; Hammes-Schiffer, S.; Jaffer, S. A.; Kelley, S. O.; Leclerc, M.; Leo, K.; Mallouk, T. E.; Narang, P.; Schlau-Cohen, G. S.; Scholes, G. D.; Vojvodic, A.; Yam, V. W.-W.; Yang, J. Y.; Sargent, E. H. "Bioinspiration in light harvesting and catalysis", Nat. Rev. Mater. 2020, 59, 1–19. [html] [pdf]




205. Smith, P. T.; Weng, S.; Chang, C. J. "An NADH-Inspired Redox Mediator Strategy to Promote Second-Sphere Electron and Proton Transfer for Cooperative Electrochemical CO2 Reduction Catalyzed by Iron Porphyrin", Inorg. Chem. 2020, 59, 9270–9278. [html] [pdf]




204. Loipersberger, M.; Zee, D. Z.; Panetier, J. A.; Chang, C. J.; Long, J. R.; Head-Gordon, M. "Computational Study of an Iron(II) Polypyridine Electrocatalyst for CO2 Reduction: Key Roles for Intramolecular Interactions in CO2 Binding and Proton Transfer" Inorg. Chem. 2020, 59, 8146–8160. DOI: 10.1021/acs.inorgchem.0c00454 [html] [pdf]




203. Protchenko, O.; Baratz, E.; Jadhav, S.; Li, F.; Shakoury-Elizeh, M.; Gavrilova, O.; Ghosh, M. C.; Cox, J. E.; Maschek, J. A.; Tyurin, V. A.; Tyurina, Y. Y.; Bayir, H.; Aron, A. T.; Chang, C. J.; Kagan, V. E.; Philpott, C. C. "Iron chaperone PCBP1 protects murine liver from lipid peroxidation and steatosis," Hepatology 2020, DOI: 10.1002/hep.31328 [html] [pdf]




202. Ueno, K.; Morstein, J.; Ofusa, K.; Naganos, S.; Suzuki-Sawano, E.; Minegishi, S.; Rezgui, S. P.; Kitagishi, H.; Michel, B. W.; Chang, C. J.; Horiuchi, J.; Saitoe, M. "Carbon Monoxide, a Retrograde Messenger Generated in Postsynaptic Mushroom Body Neurons, Evokes Noncanonical Dopamine Release," J. Neurosci. 2020, 40, 3533–3548. [html] [pdf]




201. Zee, D. Z.; Nippe, M.; King, A. E.; Chang, C. J.; Long, J. F. "Tuning Second Coordination Sphere Interactions in Polypyridyl-Iron Complexes to Achieve Selective Electrocatalytic Reduction of Carbon Dioxide to Carbon Monoxide," Inorg. Chem. 2020, 59, 5206–5217. [html] [pdf]




200. Smith, P. T,; Nichols, E. M.; Cao, Z.; Chang, C. J. "Hybrid Catalysts for Artificial Photosynthesis: Merging Approaches from Molecular, Materials, and Biological Catalysis", Acc. Chem. Res. 2020, 53, 575–587. [html] [pdf]




199. Elledge, S. K.; Tran, H. L.; Christian, A. H.; Steri, V.; Hann, B.; Toste, F. D.; Chang, C. J.; Wells, J. A. "Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site-specific antibody bioconjugation", Proc. Natl. Acad. Sci. USA 2020, 117, 5733–5740. [html] [pdf]




198. Venkatesh, D.; O'Brien, N. A,; Zandkarimi, F.; Tong, D. R.; Stokes, M. E.; Dunn, D. E.; Kengmana, E.S.; Aron, A. T.; Klein, A. M.; Csuka, J. M.; Moon, S. H.; Conrad, M.; Chang, C. J.; Lo, D. C.; D'Alessandro, A.; Prives, C.; Stockwell, B. R. "MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling", Genes Dev. 2020, 34, 526–543. [html] [pdf]




197. Liao, Y.; Zhao, J.; Bulek, K.; Tang, F.; Chen, X.; Cai, G.; Jia, S.; Fox, P. L.; Huang, E.; Pizarro, T. T.; Kalady, M. F.; Jackson, M. W.; Bao, S.; Sen, G. C.; Stark, G. R.; Chang, C.J.; Li, X. "Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis", Nat. Commun. 2020, 11, 900. [html] [pdf]




196. Ohata, J.; Krishnamoorthy, L.; Gonzalez, M. A.; Xiao, T.; Iovan, D. A.; Toste, F. D.; Miller, E. W.; Chang, C. J. "An Activity-Based Methionine Bioconjugation Approach To Developing Proximity-Activated Imaging Reporters", ACS Cent. Sci. 2020, 6, 32-40. [html] [pdf]




195. Smith, P. T.; Kim, Y.; Benke, B. P.; Kim, K.; Chang, C. J. "Supramolecular Tuning Enables Selective Oxygen Reduction Catalyzed by Cobalt Porphyrins for Direct Electrosynthesis of Hydrogen Peroxide", Angew. Chemie. Int. Ed. 2020, 59, 4902-4907. [html] [pdf]




194. Huff, T. C.; Camarena, V.; Sant, D. W.; Wilkes, Z.; Van Booven, D.; Aron, A. T.; Muir, R. K.; Renslo, A. R.; Chang, C. J.; Monje, P. V.; Wang, G. "Oscillatory cAMP signaling rapidly alters H3K4 methylation.", Life Sci. Alliance 2019, 3, e201900529. [html] [pdf]




193. Ohata, J.; Bruemmer, K. J.; Chang, C. J. "Activity-Based Sensing Methods for Monitoring the Reactive Carbon Species Carbon Monoxide and Formaldehyde in Living Systems", Acc. Chem. Res. 2019, 52, 2841-2848. [html] [pdf]




192. Chung, C. Y.; Posimo, J. M.; Lee, S.;, Tsang, T.; Davis, J. M.; Brady, D. C.; Chang, C. J. "Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism", Proc. Natl. Acad. Sci. USA 2019, 116, 18285-18294. [html] [pdf]




191. Christian, A. H.; Jia, S.; Cao, W.; Zhang, P.; Meza, A. T.; Sigman, M. S.; Chang, C. J.; Toste, F. D. "A Physical Organic Approach to Tuning Reagents for Selective andStable Methionine Bioconjugation", J. Am. Chem. Soc. 2019, 141, 12657-12662. [html] [pdf]




190. Su, T. A.; Bruemmer, K. J.; Chang, C. J.; "Caged luciferins for bioluminescent activity-based sensing", Curr. Opin. Biotechnology 2019, 60, 198-204. [html] [pdf]




189. Iovan, D. A.; Jia, S.; Chang, C. J.; "Inorganic Chemistry Approaches to Activity-Based Sensing: From Metal Sensors to Bioorthogonal Metal Chemistry", Inorg Chem 2019, 58, 13546-13560. [html] [pdf]




188. Lee, S.; Uliana, A.; Taylor, M. K.; Chakarawet, K.; Rama, S.; Bandaru, S.; Gul, S.; Xu, J.; Ackerman, C. M.; Chatterjee, R.; Furukawa, H.; Reimer, J. A.; Yano, J.; Gadgil, A.; Long, G. J.; Grandjean, F.; Long, J. R.; Chang, C. J.; Iron detection and remediation with a functionalized porous polymer applied to environmental water sample", Chem. Sci. 2019, 10, 6651. [html] [pdf]




187. Baldari, S.; Di Rocco, G.; Heffern, M. C.; Su, T. A.; Chang, C. J.; Toietta, G. "Effects of Copper Chelation on BRAFV600E Positive Colon Carcinoma Cells", Cancers 2019, 11, 659. [html]




186. Jia, S.; He, D.; Chang, C. J.; "Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation", J. Am. Chem. Soc. 2019, 141, 7294-7301. [html] [pdf]




185. Su, T. A.; Shihadih, D. A.; Cao, w.; Detomasi, T. C..; Heffern, M. C.; Jia, S.; Stahl, A.; Chang, C. J.; "A Modular Ionophore Platform for Liver-Directed Copper Supplementation in Cells and Animals", J. Am. Chem. Soc. 2018, 140, 13764-13774. [html] [pdf] [JACS Spotlights]




184. Juttukonda, L. J.; Green, E. R.; Lonergan, Z. R.; Heffern, M. C.; Chang, C. J.; Skaar, E. P.; "Acinetobacter baumannii OxyR regulates the transcriptional response to hydrogen peroxide", Infection and Immunity 2018, 87, e00413-418. [html] [pdf]




183. Nichols, E. M.; Chang, C. J.; "Urea-Based Multipoint Hydrogen-Bond Donor Additive Promotes Electrochemical CO2 Reduction Catalyzed by Nickel Cyclam", Organometallics 2018, 38, 1213-1218. [html] [pdf]




182. Smith, P. T.; Benke, B. P.; Cao, Z.; Kim, Y.; Nichols, E. M.; Kim, K.; Chang, C. J.; "Iron Porphyrins Embedded into a Supramolecular Porous Organic Cage for Electrochemical CO2 Reduction in Water", Angew. Chem. Int. Ed. 2018, 57, 9684-9688. [html] [pdf]




181. Krishnamoorthy, L.; Chang, C. J.; "Exosomal NADPH Oxidase: Delivering Redox Signaling for Healing", Biochemistry 2018, 57, 3993-3994. [html] [pdf]




180. Xiao, T.; Ackerman, C. M.; Carroll, E. C.; Jia, S.; Hoagland, A.; Chan, J.; Thai, B.; Liu, C. S.; Isacoff, E. Y.; Chang, C. J.; "Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system", Nature Chem. Biol. 2018, 14, 655-663. [html] [pdf] [C&EN] [HWNI]




179. Chung, C. Y. S.; Timblin, G. A.; Saijo, K.; Chang, C. J.; "Versatile Histochemical Approach to Detection of Hydrogen Peroxide in Cells and Tissues Based on Puromycin Staining", J. Am. Chem. Soc. 2018, 140, 6109-6121. [html] [pdf]




178. Bruemmer, K. J.; Green, O.; Su, T. A.; Shabat, D.; Chang, C. J.; "Chemiluminescent Probes for Activity-Based Sensing of Formaldehyde Released from Folate Degradation in Living Mice", Angew. Chem. Int. Ed. 2018, 57, 7508-7512. [html] [pdf]




177. Ackerman, C. M.; Weber, P. K.; Xiao, T.; Thai, B.; Kuo, T. J.; Zhang, E.; Pett-Ridge, J.; Chang, C. J.; "Multimodal LA-ICP-MS and nanoSIMS imaging enables copper mapping within photoreceptor megamitochondria in a zebrafish model of Menkes disease", Metallomics 2018, 10, 474-485. [html] [pdf]




176. Cao, Z.*; Derrick, J. S.*; Xu, J.*; Gao, R.; Gong, M.; Nichols, E. M.; Smith, P. T.; Liu, X.; Wen, X.; Coperet, C.; Chang, C. J.; "Chelating N-Heterocyclic Carbene Ligands Enable Tuning of Electrocatalytic CO2 Reduction to Formate and Carbon Monoxide through Surface Organometallic Chemistry", Angew. Chem. Int. Ed. 2018, 57, 4981-4985. [html] [pdf]




175. Nichols, E. M.*; Derrick, J. S.*; Nistanaki, S. K.; Smith, P. T.; Chang, C. J.; "Positional effects of second-sphere amide pendants on electrochemical CO2 reduction catalyzed by iron porphyrins", Chem. Sci. 2018, 9, 2952-2960. [html] [pdf]




174. Jia, S.*; Ramos-Torres, K. M.*; Kolemen, S.; Ackerman, C. M.; Chang, C. J.; "Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores", ACS Chem. Biol. 2018, 13, 1844-1852. [html] [pdf]




173. Diercks, C. S.; Lin, S.; Kornienko, N.; Kapustin, E. A.; Nichols, E. M.; Zhu, C.; Zhao, Y.; Chang, C. J.; Yaghi. O. M. "Reticular Electronic Tuning of Porphyrin Active Sites in Covalent Organic Frameworks for Electrocatalytic Carbon Dioxide Reduction", J. Am. Chem. Soc. 2018, 140, 1116-1122. [html] [pdf]




172. Aron, A. T.; Reeves, A. G.; Chang, C. J.; "Activity-based sensing fluorescent probes for iron in biological systems", Curr. Opin. Chem. Biol. 2018, 43, 113-118. [html] [pdf]




171. Camarena, V.; Sant, D. W.; Huff, T. C.; Mustafi, S.; Muir, R. K,; Aron, A. T.; Chang, C. J.; Renslo, A. R.; Monje, P. V.; Wang, G.; "cAMP signaling regulates DNA hydroxymethylation by augmenting the intracellular labile ferrous iron pool", eLIFE 2017, 6, e29750. [html]




170. Ackerman, C. M.; Chang, C. J.; "Copper Signaling in the Brain and Beyond", J. Biol. Chem. 2017, 293, 4628-4635. [html]




169. Aron, A. T.*; Heffern, M. C.*; Lonergan, Z. R.*; Vander Wal, M. N.; Blank, B. R.; Spangler, B.; Zhang, Y.; Park, H. M.; Stahl, A.; Renslo, A. R.; Skaar, E. P.; Chang, C. J.; "In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection", Proc. Natl. Acad. Sci. USA 2017, 114, 12669–12674. [html] [pdf]




168. Gong, M.*; Cao, Z.*; Liu, W.*; Nichols, E. M.; Smith, P. T.; Derrick, J. S.; Liu, Y. S.; Liu, J.; Wen, X.; Chang, C. J.; "Supramolecular Porphyrin Cages Assembled at Molecular–Materials Interfaces for Electrocatalytic CO Reduction", ACS Cent. Sci. 2017, 3, 1032-1040. [html] [pdf]




167. Burgos-Barragan, G.; Wit, N.; Meiser, J.; Dingler, F. A.; Pietzke, M.; Mulderrig, L.; Pontel, L. B.; Rosado, I. V.; Brewer, T. F.; Cordell, R. L.; Monks, P. S.; Chang, C. J.; Vazquez, A.; Patel, K. J. "Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism", Nature 2017, 548, 549-554. [html] [pdf]




166. Bruemmer, K. J.*; Brewer, T. F.*; Chang, C. J. "Fluorescent probes for imaging formaldehyde in biological systems", Curr. Opin. Chem. Biol. 2017, 39, 17-23. [html] [pdf]




165. Brewer, T. F.; Burgos-Barragan, G.; Wit, N.; Patel, K. J.; Chang, C. J. "A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in living cells", Chem. Sci. 2017, 8, 4073-4081. [html] [pdf]




164. Bruemmer, K. J.*; Walvoord, R. R.*; Brewer, T. F.; Burgos-Barragan, G.; Wit, N.; Pontel, L. B.; Patel, K. J.; Chang, C. J. "Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde in Living Cells", J. Am. Chem. Soc. 2017, 139, 5338-5350. [html] [pdf]




163. Chang, C. J. "Bioinorganic Life and Neural Activity: Toward a Chemistry of Consciousness?", Acc. Chem. Res. 2017, 50, 535-538. [html] [pdf]




162. Lin, S.; Yang, X.; Jia, S.; Weeks, A. M.; Hornsby, M.; Lee, P. S.; Nichiporuk, R. V.; Iavarone, A. T.; Wells, J. A.; Toste, F. D.; Chang, C. J. "Redox-based reagents for chemoselective methionine bioconjugation", Science 2017, 355, 597-602. [html] [pdf] [C&E News] [Berkeley Lab] [Phys. Org] [In the Pipeline] [ACS Chem. Biol.] [F1000]




161. Ackerman, C. M.; Lee, S.; Chang, C. J. "Analytical Methods for Imaging Metals in Biology: From Transition Metal Metabolism to Transition Metal Signaling", Anal. Chem. 2017, 89, 22-41. [html] [pdf]




160. Heffern, M. C.; Park, H. M.; Au-Yeung, H. Y.; Van de Bittner, G. C.; Ackerman, C. M.; Stahl, A. Chang, C. J. "In vivo bioluminescence imaging reveals copper deficiency in a murine model of nonalcoholic fatty liver disease", Proc. Natl. Acad. Sci. USA 2016, 113, 14219-14224. [html] [pdf]




159. Kashif, M. K.; Milhuisen, R. A.; Nippe, M.; Hellerstedt, J.; Zee, D. Z.; Duffy, N. W.; Halstead, B.; De Angelis, F.; Fantacci, S.; Fuhrer, M. S.; Chang, C. J.; Cheng, Y.-B.; Long, J. R.; Spiccia, L.; Bach, U. "Cobalt Polypyridyl Complexes as Transparent Solution-Processable Solid-State Charge Transport Materials", Adv. Energy Mater. 2016, 1600874. [html] [pdf]




158. Aron, A. T.; Loehr, M. O.; Bogena, J.; Chang, C. J. "An Endoperoxide Reactivity-Based FRET Probe for Ratiometric Fluorescence Imaging of Labile Iron Pools in Living Cells", J. Am. Chem. Soc. 2016, 138, 14338-14346. [html] [pdf]




157. Rodella, U.; Scorzeto, M.; Duregotti, E.; Negro, S.; Dickinson, B. C.; Chang, C. J.; Yuki, N.; Rigoni, M.; Montecucco, C. "An animal model of Miller Fisher syndrome: Mitochondrial hydrogen peroxide is produced by the autoimmune attack of nerve terminals and activates Schwann cells", Neurobiol. Dis. 2016, 96, 95-104. [html] [pdf]




156. Cox, A. G.; Tsomides, A.; Kim, A. J.; Saunders, D.; Hwang, K. L.; Evason, K. J.; Heidel, J.; Brown, K. K.; Yuan, M.; Lien, E. C.; Lee, B. C.; Nissim, S.; Dickinson, B. C.; Chhangawala, D.; Chang, C. J.; Asara, J. M.; Houvras, Y.; Gladyshev, V. N.; Goessling, W. "Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis", Proc. Natl. Acas. Sci. U. S. A. 2016, 113, E5562-E5571. [html] [pdf]




155. Ramos-Torres, K. M.; Kolemen, S.; Chang, C. J. "Thioether Coordination Chemistry for Molecular Imaging of Copper in Biological Systems", Isr. J. Chem. 2016, 56, 724-737. [html] [pdf]




154. Axelson, J. C.; Gonzalez, M. I.; Meihaus, K. R.; Chang, C. J.; Long, J. R. "Synthesis and Characterization of a Tetrapodal NO44- Ligand and Its Transition Metal Complexes", Inorg. Chem. 2016, 55, 7527-7534. [html] [pdf]




153. Spangler, B.; Morgan, C. W.; Fontaine, S. D.; Vander Wal, M. N.; Chang, C. J.; Wells, J. A.; Renslo, A. R. "A reactivity-based probe of the intracellular labile ferrous iron pool", Nature Chem. Biol. 2016, 12, 680-685. [html] [pdf]




152. Cao, Z.; Kim, D.; Yu, Y.; Xu, J.; Lin, S.; Wen, X.; Nichols, E. M.; Jeong, K.; Reimer, J. A.; Yang, P.; Chang, C. J. "A Molecular Surface Functionalization Approach to Tuning Nanoparticle Electrocatalysts for Carbon Dioxide Reduction", J. Am. Chem. Soc. 2016, 138, 8120-8125. [html] [pdf]




151. Lee, S.; Barin, G.; Ackerman, C. M.; Muchenditsi, A.; Xu, J.; Reimer, J. A.; Lutsenko, S.; Long, J. R.; Chang, C. J. "Copper Capture in a Thioether-Functionalized Porous Polymer Applied to the Detection of Wilson's Disease", J. Am. Chem. Soc. 2016, 138, 7603-7609. [html] [pdf]




150. Krishnamoorthy, L.; Cotruvo, Jr., J. A.; Chan, J.; Kaluarachchi, H.; Muchenditsi, A.; Pendyala, V. S.; Jia, S.; Aron, A. T.; Ackerman, C. M.; Vander Wal, M. N.; Guan, T.; Smaga, L. P.; Farhi, S. L.; New, E. J.; Lutsenko, S.; Chang, C. J. "Copper regulates cyclic-AMP-dependent lipolysis", Nature Chem. Biol. 2016, 12, 586-592. [html] [pdf] [Biomedical Beat Story] [UC Science Today Segment] [PictureFit YouTube Video] [LBNL News Story] [UC Berkeley News Story] [Daily Mail News Story] [Genetic Engineering and Biotechnology News Story] [Dr Oz Reviews Story] [Men's Fitness Story] [Deccan Herald News Story] [Fitness First Mag Story] [Indo Asian News Service Story] [Health Canal News Story] [First Post News Story] [Business Standard News Story] [The Health Site News Story] [Hindustan Times News Story] [Can-India News Story] [Natural Science News Story] [Times of India News Story] [Money Control News Story] [American Council on Science and Health News Story] [China Topix News Story] [MSN News Story] [Press Liberal News Story] [Headlines News Story] [The Sentinel News Story] [Brief Report News Story] [Engine News Story] [3 Novices News Story] [HT Syndication News Story] [New York Indian News Story]




149. Liu, W.; Truillet, C.; Flavell, R. R.; Brewer, T. F.; Evans, M. J.; Wilson, D. M.; Chang, C. J. "A reactivity-based [18F]FDG probe for in vivo formaldehyde imaging using positron emission tomography", Chem. Sci. 2016, 7, 5503-5507. [html] [pdf]




148. Tomalin, L. E.; Day, A. M.; Underwood, Z. E.; Smith, G. R.; Pezze, P. D.; Rallis, C.; Patel, W.; Dickinson, B. C.; Bahler, J.; Brewer, T. F.; Chang, C. J.; Shanley, D. P.; Veal, E. A. "Increasing extracellular H2O2 produces a bi-phasic response in intracellular H2O2, with peroxiredoxin hyperoxidation only triggered once the cellular H2O2-buffering capacity is overwhelmed", Free Radic. Biol. Med. 2016, 95, 333-348. [html] [pdf]




147. Flavell, R. R.; Truillet, C.; Regan, M. K.; Ganguly, T.; Blecha, J. E.; Kurhanewicz, J.; VanBrocklin, H. F.; Keshari, K. R.; Chang, C. J.; Evans, M. J.; Wilson, D. M. "Caged [18F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography", Bioconjugate Chem. 2016, 27, 170-178. [html] [pdf]




146. Kornienko, N.; Zhao, Y.; Kley, C. S.; Zhu, C.; Kim, D.; Lin, S.; Chang, C. J.; Yaghi, O. M.; Yang, P. "Metal–Organic Frameworks for Electrocatalytic Reduction of Carbon Dioxide", J. Am. Chem. Soc. 2015, 137, 14129-14135. [html] [pdf]




145. Chang, C. J. "Searching for Harmony in Transition-Metal Signaling", Nature Chem. Biol. 2015, 111, 744-747. [html] [pdf]




144. Brewer, T. F.; Chang, C. J. "An Aza-Cope Reactivity-Based Fluorescent Probe for Imaging Formaldehyde in Living Cells", J. Am. Chem. Soc. 2015, 37, 10886-10889. [html] [pdf] [Chemical & Engineering News Story]




143. Nichols, E. M.; Gallagher, J. J.; Liu, C.; Su, Y.; Resasco, J.; Yu, Y.; Sun, Y.; Yang, P.; Chang, M. C. Y.; Chang, C. J. "Hybrid bioinorganic approach to solar-to-chemical conversion", Proc. Natl. Acad. Sci. USA 2015, 112, 11461-11466. [html] [pdf] [LBNL News Story] [ScienceDaily News Story] [Demanjo News Story] [Science Newsline News Story] [Tech News Coverage News Story] [Adaptive Scientist News Story] [Guldar News Story] [DOE Science Headlines]




142. Lin, S.; Diercks, C. S.; Zhang, Y.; Kornienko, N.; Nichols, E. M.; Zhao, Y.; Paris, A. R.; Kim, D.; Yang, P.; Yaghi, O. M.; Chang, C. J. "Covalent organic frameworks comprising cobalt porphyrins for catalytic CO2 reduction in water", Science 2015, 346, 1208-1213. [html] [pdf] [LBNL News Story] [Science News Story]




141. Aron, A. T.; Ramos-Torres, K. M.; Cotruvo, Jr., J. A.; Chang, C. J. "Recognition- and Reactivity-Based Fluorescent Probes for Studying Transition Metal Signaling in Living Systems", Acc. Chem. Res. 2015, 48, 2434-2442. [html] [pdf]




140. Zee, D. Z.; Chantarojsiri, T.; Long, J. R.; Chang, C. J. "Metal-Polypyridyl Catalysts for Electro- and Photochemical Reduction of Water to Hydrogen", Acc. Chem. Res. 2015, 48, 2027-2036. [html] [pdf]




139. Jurss, J. W.; Khnayzer, R. S.; Panetier, J. A.; El Roz, K. A.; Nichols, E. M.; Head-Gordon, M.; Long, J. R.; Castellano, F. N.; Chang, C. J. "Bioinspired design of redox-active ligands for multielectron catalysis: effects of positioning pyrazine reservoirs on cobalt for electro- and photocatalytic generation of hydrogen from water", Chem. Sci. 2015, 6, 4954-4972. [html] [pdf]




138. Chantarojsiri, T.; Sun, Y.; Long, J. R.; Chang, C. J. "Water-Soluble Iron(IV)-Oxo Complexes Supported by Pentapyridine Ligands: Axial Ligand Effects on Hydrogen Atom and Oxygen Atom Transfer Reactivity", Inorg. Chem. 2015, 54, 5879-5887. [html] [pdf]




137. Brewer, T. F.; Garcia, F. J.; Onak, C. S.; Carroll, K. S.; Chang, C. J. "Chemical Approaches to Discovery and Study of Sources and Targets of Hydrogen Peroxide Redox Signaling Through NADPH Oxidase Proteins", Annu. Rev. Biochem. 2015, 84, 765-790. [html] [pdf]




136. Liu, C.; Gallagher, J. J.; Sakimoto, K. K.; Nichols, E. M.; Chang, C. J.; Chang, M. C. Y.; Yang, P. "Nanowire–Bacteria Hybrids for Unassisted Solar Carbon Dioxide Fixation to Value-Added Chemicals", Nano Lett. 2015, 15, 3634-3639. [html] [pdf] [LBNL News Story] [Tech Times News Story] [Science Times News Story] [News Everyday News Story] [DOE Science Headline] [Huffington Post article] [Statesman article]




135. Lin, V. S.; Lippert, A. R.; Chang, C. J. "Azide-Based Fluorescent Probes: Imaging Hydrogen Sulfide in Living Systems", Meth. Enzymol. 2015, 554, 63-80 (Chapter 4 in Hydrogen Sulfide in Redox Biology, Part A). [html] [pdf]




134. Fu, X.; Tang, Y.; Dickinson, B. C.; Chang, C. J.; Chang, Z. "An oxidative fluctuation hypothesis of aging generated by imaging H2O2 levels in live Caenorhabditis elegans with altered lifespans", Biochem. Biophys. Res. Commun. 2015, 458, 896-900. [html] [pdf]




133. Cotruvo, Jr., J. A.; Aron, A. T.; Ramos-Torres, K. M.; Chang, C. J. "Synthetic fluorescent probes for studying copper in biological systems", Chem. Soc. Rev. 2015, 44, 4400-4414. [html] [pdf]




132. Lin, V. S.; Chen, W.; Xian, M.; Chang, C. J. "Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems", Chem. Soc. Rev. 2015, 44, 4596-4618. [html] [pdf]




131. Duregotti, E.; Negro, S.; Scorzeto, M.; Zornetta, I.; Dickinson, B. C.; Chang, C. J.; Montecucco, C.; Rigoni, M. "Mitochondrial alarmins released by degenerating motor axon terminals activate perisynaptic Schwann cells", Proc. Natl. Acad. Sci. USA 2015, 112, E497-E505. [html] [pdf]




130. Dodani, S. C.; Firl, A.; Chan, J.; Nam, C. I.; Aron, A. T.; Onak, C. S.; Ramos-Torres, K. M.; Paek, J.; Webster, C. W.; Feller, M. B.; Chang, C. J. "Copper is an endogenous modulator of neural circuit spontaneous activity", Proc. Natl. Acad. Sci. USA 2014, 111, 16280-16285. [html] [pdf] [LBNL News Story] [C&E News Story] [R&D Magazine News Story]




129. Hong-Hermesdorf, A.; Miethke, M.; Gallaher, S. D.; Kropat, J.; Dodani, S. C.; Chan, J.; Barupala, D.; Domaille, D. W.; Shirasaki, S. I.; Loo, J. A.; Weber, P. K.; Pett-Ridge, J.; Stemmler, T. L.; Chang, C. J.; Merchant, S. S. "Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas", Nature Chem. Biol. 2014, 10, 1034-1042. [html] [pdf]




128. Carroll, V.; Michel, B. W.; Blecha, J.; VanBrocklin, H.; Keshari, K.; Wilson, D.; Chang, C. J. "A Boronate-Caged [18F]FLT Probe for Hydrogen Peroxide Detection Using Positron Emission Tomography", J. Am. Chem. Soc. 2014, 136, 14742-14745. [html] [pdf]




127. Yang, M.; Haase, A. D.; Huang, F.; Coulis, G.; Rivera, K. D.; Dickinson, B. C.; Chang, C. J.; Pappin, D. J.; Neubert, T. A.; Hannon, G. J.; Boivin, B.; Tonks, N. K. "Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence", Mol. Cell 2014, 55, 782-790. [html] [pdf]




126. Sanders, L. H.; McCoy, J.; Hu, X.; Mastroberardino, P. G.; Dickinson, B. C.; Chang, C. J.; Chu, C. T.; Van Houten, B.; Greenamyre, J. T. "Mitochondrial DNA damage: Molecular marker of vulnerable nigral neurons in Parkinson's disease", Neurobiol. Dis. 2014, 70, 214-223. [html] [pdf]




125. King, A. E.; Nippe, M.; Atanasov, M.; Chantarojsiri, T.; Wray, C.; Bill, E.; Neese, f.; Long, J. R.; Chang, C. J. "A Well-Defined Terminal Vanadium(III) Oxo Complex", Inorg. Chem. 2014, 53, 11388-11395. [html] [pdf]




124. Polishchuk, E. V.; Concilli, M.; Iacobacci, S.; Chesi, G.; Pastore, N.; Piccolo, P.; Paladino, S.; Baldantoni, D.; van IJzendoorn, S. C. D.; Chan, J.; Chang, C. J.; Amoresano, A.; Pane, F.; Pucci, P.; Tarallo, A.; Parenti, G.; Brunetti-Pierri, N.; Settembre, C.; Ballabio, A.; Polishchuk, R. S. "Wilson Disease Protein ATP7B Utilizes Lysosomal Exocytosis to Maintain Copper Homeostasis", Dev. Cell 2014, 29, 686-700. [html] [pdf]




123. Kashyap, D. R.; Rompca, A.; Gaballa, A.; Helmann, J. D.; Chan, J.; Chang, C. J.; Hozo, I.; Gupta, D.; Dziarski, R. "Peptidoglycan Recognition Proteins Kill Bacteria by Inducing Oxidative, Thiol, and Metal Stress", PLoS Pathog. 2014, 10, e1004280. [html] [pdf]




122. Basu, S.; Rajakaruna, S.; Dickinson, B. C.; Chang, C. J.; Menko, A. S. "Endogenous hydrogen peroxide production in the epithelium of the developing embryonic lens", Mol. Vis. 2014, 20, 458. [html] [pdf]




121. Banerjee, J.; Das Ghatak, P.; Roy, S.; Khanna, S.; Sequin, E. K.; Bellman, K.; Dickinson, B. C.; Suri, P.; Subramaniam, V. V.; Chang, C. J.; Sen, C. K. "Improvement of Human Keratinocyte Migration by a Redox Active Bioelectric Dressing", PLoS One 2014, 9, e89239. [html] [pdf]




120. Khnayzer, R. S.; Thoi, V. S.; Nippe, M.; King, A. E.; Jurss, J. W.; El Roz, K. A.; Long, J. R.; Chang, C. J.; Castellano, F. N. "Towards a comprehensive understanding of visible-light photogeneration of hydrogen from water using cobalt(II) polypyridyl catalysts", Energy Environ. Sci. 2014, 7, 1477-1488. [html] [pdf]




119. Huang, C. P.; Fofana, M.; Chan, J.; Chang, C. J.; Howell, S. B. "Copper transporter 2 regulates intracellular copper and sensitivity to cisplatin", Metallomics 2014, 6, 654-661. [html] [pdf]




118. Boivin, B.; Chaudhary, F.; Dickinson, B. C.; Haque, A.; Pero, S. C.; Chang, C. J.; Tonks, N. K. "Receptor Protein-tyrosine Phosphatase α Regulates Focal Adhesion Kinase Phosphorylation and ErbB2 Oncoprotein-mediated Mammary Epithelial Cell Motility", J. Biol. Chem. 2013, 288, 36926-36935. [html] [pdf]




117. Sun, Y.; Liu, C.; Grauer, D. C.; Yano, J.; Long, J. R.; Yang, P.; Chang, C. J. "Electrodeposited Cobalt-Sulfide Catalyst for Electrochemical and Photoelectrochemical Hydrogen Generation from Water", J. Am. Chem. Soc. 2013, 135, 17699-17702. [html] [pdf]




116. Au-Yeung, H. Y.; Chan, J.; Chantarojsiri, T.; Chang, C. J. "Molecular Imaging of Labile Iron(II) Pools in Living Cells with a Turn-On Fluorescent Probe", J. Am. Chem. Soc. 2013, 135, 15165-15173. [html] [pdf]




115. Nippe, M.; Khnayzer, R. S.; Panetier, J. A.; Zee, D. Z.; Olaiya, B. S.; Head-Gordon, M.; Chang, C. J.; Castellano, F. N.; Long, J. R. "Catalytic Proton Reduction with Transition Metal Complexes of the Redox-active Ligand bpy2PYMe", Chem. Sci. 2013, 4, 3934-3945. [html] [pdf]




114. Thoi, V. S.; Kornienko, N.; Margarit, C. G.; Yang, P.; Chang, C. J. "Visible-Light Photoredox Catalysis: Selective Reduction of Carbon Dioxide to Carbon Monoxide by a Nickel N-Heterocyclic Carbene-Isoquinoline Complex", J. Am. Chem. Soc. 2013, 135, 14413-14424. [html] [pdf]




113. Lin, V. S.; Dickinson, B. C.; Chang, C. J. "Boronate-Based Fluorescent Probes: Imaging Hydrogen Peroxide in Living Systems", Meth. Enzymol. 2013, 526, 19-43 (Chapter 2 in Hydrogen Peroxide and Cell Signaling, Part A). [html]




112. Dickinson, B. C.; Lin, V. S.; Chang, C. J. "Preparation and Use of MitoPY1 for Imaging Hydrogen Peroxide in Mitochondria of Live Cells", Nature Protoc. 2013, 8, 1249-1259. [pdf] [html]




111. Kashif, M. K.; Nippe, M.; Duffy, N. W.; Forsyth, C. M.; Chang, C. J.; Long, J. R.; Spiccia, L.; Bach, U.; "Stable Dye-Sensitized Solar Cell Electrolytes Based on Cobalt(II)/(III) Complexes of a Hexadentate Pyridyl Ligand", Angew. Chem. Int. Ed. 2013, 52, 5527-5531. [html] [pdf]




110. Lin, V. S.; Lippert, A. R.; Chang, C. J. "Cell-trappable Fluorescent Probes for Endogenous Hydrogen Sulfide Signaling and Imaging H2O2-Dependent H2S Production", Proc. Natl. Acad. Sci. USA 2013, 110, 7131-7135. [pdf] [html] [C&E News] [CRT Spotlight] [Faculty of 1000 Recommendation]




109. King, A. E.; Surendranath, Y.; Piro, N. A.; Bigi, J. P.; Long, J. R.; Chang, C. J. "A Mechanistic Study of Proton Reduction Catalyzed by a Pentapyridine Cobalt Complex: Evidence for Involvement of an Anation-Based Pathway", Chem. Sci. 2013, 4, 1578-1587. [pdf] [html]




108. Harris, J. M.; Esain, V.; Frechette, G. M.; Harris, L. J.; Cox, A. G.; Cortes, M.; Garnaas, M. K.; Carroll, K. J.; Cutting, C. C.; Khan, T.; Elks, P. M.; Renshaw, S. A.; Dickinson, B. C.; Chang, C. J.; Murphy, M. P.; Paw, B. H.; Vander Heiden, M. G.; Goessling, W.; North, T. E.; "Glucose Metabolism Impacts the Spatiotemporal Onset and Magnitude of HSC Induction in Vivo", Blood 2013, 121, 2483-2493. [pdf] [html]




107. Thoi, V. S.; Sun, Y.; Long, J. R.; Chang, C. J. "Complexes of earth-abundant metals for catalytic electrochemical hydrogen generation under aqueous conditions", Chem. Soc. Rev. 2013, 42, 2388-2400. [pdf] [html]




106. Van de Bittner, G. C.; Bertozzi, C. R.; Chang, C. J. "Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation", J. Am. Chem. Soc. 2013, 135, 1783-1795. [pdf] [html]




105. Sun, Y.; Sun, J.; Long, J. R.; Yang, P.; Chang, C. J. "Photocatalytic generation of hydrogen from water using a cobalt pentapyridine complex in combination with molecular and semiconductor nanowire photosensitizers", Chem. Sci. 2013, 4, 118-124. [pdf] [html]




104. Sakai, J.; Li, J.; Subramanian, K. K.; Mondal, S.; Bajrami, B.; Hattori, H.; Jia, Y.; Dickinson, B. C.; Zhong, J.; Ye, K.; Chang, C. J.; Ho, Y.-S.; Zhou, J.; Luo, H. R. "Reactive Oxygen Species-Induced Actin Glutathionylation Controls Actin Dynamics in Neutrophils", Immunity 2012, 37, 1037-1049. [html]




103. Chan, J.; Dodani, S. C.; Chang, C. J. "Reaction-based small-molecule fluorescent probes for chemoselective bioimaging", Nature Chem. 2012, 4, 973-984. [pdf] [html]




102. Kashif, M. K.; Axelson, J. C.; Duffy, N. W.; Forsyth, C. M.; Chang, C.J.; Long, J. R.; Spiccia, L.; Bach, U. "A New Direction in Dye-Sensitized Solar Cells Redox Mediator Development: In Situ Fine-Tuning of the Cobalt(II)/(III) Redox Potential through Lewis Base Interactions", J. Am. Chem. Soc. 2012, 134, 16646-16653. [pdf] [html]




101. Lin, V. S.; Chang, C. J. "Fluorescent probes for sensing and imaging biological hydrogen sulfide", Curr. Opin. Chem. Biol. 2012, 16, 595-601. [pdf] [html]




100. Michel, B. W.; Lippert, A. R.; Chang, C. J. "A Reaction-Based Fluorescent Probe for Selective Imaging of Carbon Monoxide in Living Cells Using a Palladium-Mediated Carbonylation", J. Am. Chem. Soc. 2012, 134, 15668-15671. [pdf] [html] [C&E News]




99. Harman, W. H.; Lichterman, M. F.; Piro, N. A.; Chang, C. J. "Well-Defined Vanadium Organoazide Complexes and Their Conversion to Terminal Vanadium Imides: Structural Snapshots and Evidence for a Nitrene Capture Mechanism", Inorg. Chem. 2012, 51, 10037-10042. [pdf] [html]




98. Hu, C.; Mori, T.; Lu, Y.; Guo, Q.; Sun, Y.; Yoneki, Y.; Ohsaki, Y.; Nakamichi, T.; Oba, I.; Sato, E.; Ogawa, S.; Dickinson, B. C.; Chang, C. J.; Miyata, T.; Sato, H.; Ito, S. "Role of specific T-type calcium channel blocker R(-) efonidipine in the regulation of renal medullary circulation", J. Hypertens. 2012, 30, 1620-1631. [pdf] [html]




97. Woolley, J. F.; Naughton, R.; Stanicka, J.; Gough, D. R.; Bhatt, L.; Dickinson, B. C.; Chang, C. J.; Cotter, T. G. "H2O2 Production Downstream of FLT3 Is Mediated by p22phox in the Endoplasmic Reticulum and Is Required for STAT5 Signalling", PLoS One 2012, 7, e34050. [pdf] [html]




96. Au-Yeung, H. Y.; New, E. J.; Chang, C. J. "A selective reaction-based fluorescent probe for detecting cobalt in living cells", Chem. Commun. 2012, 48, 5268-5270. [pdf] [html]




95. Thoi, V. S.; Karunadasa, H. I.; Surendranath, Y.; Long, J. R.; Chang, C. J.; "Electrochemical generation of hydrogen from acetic acid using a molecular molybdenum-oxo catalyst", Energy Environ. Sci. 2012, 5, 7762-7770. [pdf] [html]




94. Que, E. L.; New, E. J.; Chang, C. J. "A cell-permeable gadolinium contrast agent for magnetic resonance imaging of copper in a Menkes disease model", Chem. Sci. 2012, 3, 1829-1834. [pdf] [html]




93. Sundstrom, E. J.; Yang, X.; Thoi, V. S.; Karunadasa, H. I.; Chang, C. J.; Long, J. R.; Head-Gordon, M. "Computational and Experimental Study of the Mechanism of Hydrogen Generation from Water by a Molecular Molybdenum-Oxo Electrocatalyst", J. Am. Chem. Soc. 2012, 134, 5233-5242. [pdf] [html]




92. Cusick, K. D.; Minkin, Jr., S. C.; Dodani, S. C.; Chang, C. J.; Wilhelm, S. W.; Sayler G. S. "Inhibition of Copper Uptake in Yeast Reveals the Copper Transporter Ctr1p As a Potential Molecular Target of Saxitoxin", Environ. Sci. Technol. 2012, 46, 2959-2966. [pdf] [html]




91. Karunadasa, H. I.; Montalvo, E.; Sun, Y.; Majda, M.; Long, J. R.; Chang, C. J. "A Molecular MoS2 Edge Site Mimic for Catalytic Hydrogen Generation", Science 2012, 335, 698-702. [pdf] [html] [UC Berkeley press release] [LBNL press release] [Daily Cal article] [C&E News article]




90. Hirayama, T.; Van de Bittner, G. C.; Gray, L. W.; Lutsenko, S.; Chang, C. J. "Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model", Proc. Natl. Acad. Sci. USA 2012, 109, 2228-2233. [pdf] [html]




89. Zadrozny, J. M.; Liu, J.; Piro, N. A.; Chang, C. J.; Hill, S.; Long J. R. "Slow magnetic relaxation in a pseudotetrahedral cobalt(II) complex with easy-plane anisotropy", Chem. Commun. 2012, 48, 3927-3929. [pdf] [html]




88. Bigi, J. P.; Harman, W. H.; Lassalle-Kaiser, B.; Robles, D. M.; Stich, T. A.; Yano, J.; Britt, R. D.; Chang C. J. "A High-Spin Iron(IV)-Oxo Complex Supported by a Trigonal Nonheme Pyrrolide Platform", J. Am. Chem. Soc. 2012, 134, 1536-1542. [pdf] [html]




87. Ohsaki, Y.; O'Connor, P.; Mori, T.; Ryan, R. P.; Dickinson, B. C.; Chang, C. J.; Lu, Y.; Ito, S.; Cowley Jr., A. W. "Increase of Sodium Delivery Stimulates the Mitochondrial Respiratory Chain H2O2 Production in Rat Renal Medullary Thick Ascending Limb", Am. J. Physiol. Renal. Physiol. 2012, 302, F95-F102. [pdf] [html]




86. Wrighton, K. C.; Thrash, J. C.; Melnyk, R. A.; Bigi, J. P.; Byrne-Bailey, K. G. ; Remis, J. P.; Schichnes, D.; Auer, M.; Chang, C. J.; Coates, J. D. "Evidence for Direct Electron Transfer by a Gram-Positive Bacterium Isolated from a Microbial Fuel Cell", Appl. Environ. Microbiol. 2011, 77, 7633-7639. [pdf] [html]




85. Beaudoin, J.; Ioannoni, R.; López-Maury, L.; Bähler, J.; Ait-Mohand, S.; Guérin, B.; Dodani, S. C.; Chang, C. J.; Labbé, S. "Mfc1 Is a Novel Forespore Membrane Copper Transporter in Meiotic and Sporulating Cells", J. Biol. Chem. 2011, 286, 34356-34372. [pdf] [html]




84. Dickinson, B. C.; Tang, Y.; Chang, Z.; Chang, C. J. "A Nuclear-Localized Fluorescent Hydrogen Peroxide Probe for Monitoring Sirtuin-Mediated Oxidative Stress Responses In Vivo", Chem. Biol. 2011, 18, 943-948. [pdf] [html]




83. Lippert, A. R.; Van de Bittner, G. C.; Chang, C. J. "Boronate Oxidation as a Bioorthogonal Reaction Approach for Studying the Chemistry of Hydrogen Peroxide in Living Systems", Acc. Chem. Res. 2011, 44, 793-804. [pdf] [html]




82. Chung, C.; Srikun, D.; Lim, C. S.; Chang, C. J.; Cho, B. R. "A two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue", Chem. Commun. 2011, 47, 9618-9620. [pdf] [html]




81. Lu, J.; Esposito, G.; Scuderi, C.; Steardo, L.; Delli-Bovi, L. C.; Hecht, J. L.; Dickinson, B. C.; Chang, C. J.; Mori, T.; Sheen, V. "S100B and APP Promote a Gliocentric Shift and Impaired Neurogenesis in Down Syndrome Neural Progenitors", PLoS ONE 2011, 6, e22126. [pdf] [html]




80. Dickinson, B. C.; Chang, C. J. "Chemistry and biology of reactive oxygen species in signaling or stress responses", Nature Chem. Biol. 2011, 7, 504-511. [pdf] [html]




79. Lippert, A. R.; New, E. J.; Chang, C. J. "Reaction-Based Fluorescent Probes for Selective Imaging of Hydrogen Sulfide in Living Cells", J. Am. Chem. Soc. 2011, 133, 10078-10080. [pdf] [html] [C&E News]




78. Sun, Y.; Bigi, J. P.; Piro, N. A.; Tang, M. L.; Long, J. R.; Chang, C. J. "Molecular Cobalt Pentapyridine Catalysts for Generating Hydrogen from Water", J. Am. Chem. Soc. 2011, 133, 9212-9215. [pdf] [html]




77. Dodani, S. C.; Leary, S. C.; Cobine, P. A.; Winge, D. R.; Chang, C. J. "A targetable fluorescent sensor reveals that copper-deficient SCO1 and SCO2 patient cells prioritize mitochondrial copper homeostasis", J. Am. Chem. Soc. 2011, 133, 8606-8616. [pdf] [html]




76. Thoi, V. S. and Chang, C. J. "Nickel N-heterocyclic carbene-pyridine complexes that exhibit selectivity for electrocatalytic reduction of carbon dioxide over water", Chem. Commun. 2011, 47, 6578-6580. [pdf] [html]




75. Harris, T. D.; Soo, H. S.; Chang, C. J.; Long, J. R. "A cyano-bridged FeIIReIV(CN)2 cluster incorporating two high-magnetic anisotropy building units", Inorg. Chim. Acta 2011, 369, 91-96 (Special Issue in Honor of Robert G. Bergman). [pdf] [html]




74. Soo, H. S.; Sougrati, M. T.; Grandjean, F.; Long, G. J.; Chang, C. J. "A seven-coordinate iron platform and its oxo and nitrene reactivity", Inorg. Chim. Acta 2011, 369, 82-91 (Special Issue in Honor of Robert G. Bergman). [pdf] [html]




73. Murphy, M. P.; Holmgren, A.; Larsson, N.-G.; Halliwell, B.; Chang, C. J.; Kalyanaraman, B.; Rhee, S. G.; Thornalley, P. J.; Partridge, L.; Gems, D.; Nyström, T.; Belousov, V.; Schumacker, P. T.; Winterbourn, C. C. "Unraveling the Biological Roles of Reactive Oxygen Species", Cell Metab. 2011, 13, 361-366. [pdf] [html]




72. Dodani, S. C.; Domaille, D. W.; Nam, C. I.; Miller, E. W.; Finney, L. A.; Vogt, S.; Chang, C. J. "Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy", Proc. Natl. Acad. Sci. USA 2011, 108, 5980-5985. [pdf] [html]




71. Srikun, D.; Albers, A. E.; Chang, C. J. "A dendrimer-based platform for simultaneous dual fluorescence imaging of hydrogen peroxide and pH gradients produced in living cells", Chem. Sci. 2011, 2, 1156-1165. [pdf] [html]




70. Lippert, A. R.; Keshari, K. R.; Kurhanewicz, J.; Chang, C. J. "A Hydrogen Peroxide-Responsive Hyperpolarized 13C MRI Contrast Agent", J. Am. Chem. Soc. 2011, 133, 3776-3779. [pdf] [html]




69. Santo, C. E.; Lam, E. W.; Elowsky, C. G.; Quaranta, D.; Domaille, D. W.; Chang, C. J.; Grass, G. "Bacterial Killing by Dry Metallic Copper Surfaces", Appl. Environ. Microbiol. 2011, 77, 794-802. [pdf] [html]




68. Quaranta, D.; Krans, T.; Santo, C. E.; Elowsky, C. G.; Domaille, D. W.; Chang, C. J.; Grass, G. "Mechanisms of Contact-Mediated Killing of Yeast Cells on Dry Metallic Copper Surfaces", Appl. Environ. Microbiol. 2011, 77, 416-426. [pdf] [html]




67. Piro, N. A., Lichterman, M. F., Harman, W. H., Chang, C. J. "A Structurally Characterized Nitrous Oxide Complex of Vanadium", J. Am. Chem. Soc. 2011, 133, 2108-2111. [pdf] [html]




66. Schrag, M.; Crofton, A.; Zabel, M.; Jiffry, A.; Kirsch, D.; Dickson, A.; Mao, X. W.; Vinters, H. V.; Domaille, D. W.; Chang, C. J.; Kirsch, W. "Effect of cerebral amyloid angiopathy on brain iron, copper, and zinc in Alzheimer's disease", J. Alzheimers Dis. 2011, 24, 137-149. [pdf] [html]




65. Dickinson, B. C., Peltier, J., Stone, D., Schaffer, D. V., Chang, C. J. "Nox2 redox signaling maintains essential cell populations in the brain", Nature Chem. Biol. 2011, 7, 106-112. [pdf] [html]




64. Harman, W. H., Harris, T. D., Freedman, D. E., Fong, H., Chang, A., Rinehart, J. D., Ozarowski, A., Sougrati, M. T., Grandjean, F., Long, G. J., Long, J. R., Chang, C. J. "Slow Magnetic Relaxation in a Family of Trigonal Pyramidal Iron(II) Pyrrolide Complexes", J. Am. Chem. Soc. 2010, 132, 18115-18126. [pdf] [html]




63. Van de Bittner, G. C., Dubikovskaya E. A., Bertozzi, C. R., and Chang, C. J. "In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter", Proc. Natl. Acad. Sci. USA 2010, 107, 21316-21321. [pdf] [html] [Faculty of 1000 Evaluation] [LBL Highlight]




62. Miller, E. W.; Taulet, N.; Onak, C. S.; New, E. J.; Lanselle, J. K.; Smelick, G. S.; Chang, C. J. "Light-Activated Regulation of Cofilin Dynamics Using a Photocaged Hydrogen Peroxide Generator", J. Am. Chem. Soc. 2010, 132, 17071-17073. [pdf] [html]




61. Lippert, A. R.; Gschneidtner, T.; Chang, C. J. "Lanthanide-Based Luminescent Probes for Selective Time-Gated Detection of Hydrogen Peroxide in Water and in Living Cells", Chem. Commun. 2010, 46, 7510-7512. [pdf] [html]




60. Miller, E. W.; Dickinson, B. C.; Chang, C. J. "Aquaporin-3 Mediates Hydrogen Peroxide Uptake to Regulate Downstream Intracellular Signaling", Proc. Natl. Acad. Sci. USA 2010, 107, 15681-15686. [pdf] [html] [ACS Chembio Spotlight] [Faculty of 1000 Evaluation]




59. Cheng, W.-Y.; Tong, H.; Miller, E. W.; Chang, C. J.; Remington, J.; Zucker, R. M.; Bromberg, P. A.; Samet, J. M.; Hofer, T. P. J. "An Integrated Imaging Approach to the Study of Oxidative Stress Generation by Mitochondrial Dysfunction in Living Cells", Environ. Health Perspectives 2010, 118, 902-908. [pdf]




58. Karunadasa, H. I.; Chang, C. J.; Long, J. R. "A Molecular Molybdenum-Oxo Catalyst for Generating Hydrogen from Water", Nature 2010, 464, 1329-1333. [pdf]




57. Dickinson, B. C.; Huynh, C.; Chang, C. J. "A Palette of Fluorescent Probes with Varying Emission Colors for Imaging Hydrogen Peroxide Signaling in Living Cells", J. Am. Chem. Soc. 2010, 132, 5906-5915. [pdf] [html]




56. Srikun, D.; Albers, A. E.; Nam, C. I.; Iavarone, A. T.; Chang, C. J. "Organelle-Targetable Fluorescent Probes for Imaging Hydrogen Peroxide in Living Cells via SNAP-Tag Protein Labeling", J. Am. Chem. Soc. 2010, 132, 4455-4465. [pdf]




55. Freedman, D. E.; Harman, W. H.; Harris, T. D.; Long, G. J.; Chang, C. J.; Long, J. R. "Slow Magnetic Relaxation in a High-Spin Iron(II) Complex", J. Am. Chem. Soc. 2010, 132, 1224-1225. [pdf]




54. Domaille, D. W.; Zeng, L.; Chang, C. J. "Visualizing Ascorbate-Triggered Release of Labile Copper within Living Cells using a Ratiometric Fluorescent Sensor", J. Am. Chem. Soc. 2010, 132, 1194-1195. [pdf]




53. Bigi, J. P.; Hanna, T. E.; Harman, W. H.; Chang, A.; Chang, C. J. "Electrocatalytic Reduction of Protons to Hydrogen by a Water-Compatible Cobalt Polypyridyl Platform", Chem. Commun. 2010, 46, 958-960. [pdf]




52. Que, E. L.; Gianolio, E.; Baker, S. L.; Aime, S.; Chang, C. J. "A Copper-Activated Magnetic Resonance Imaging Contrast Agent with Improved Turn-On Relaxivity Response and Anion Compatibility", Dalton Trans. 2010, 39, 469-476 (Special Issue). [pdf]




51. Dickinson, B. C.; Srikun, D.; Chang, C. J. "Mitochondrial-Targeted Fluorescent Probes for Reactive Oxygen Species", Curr. Opin. Chem. Biol. 2010, 14, 50-56. [pdf]




50. Que, E. L.; Chang, C. J. "Responsive Magnetic Resonance Imaging Contast Agents as Chemical Sensors for Metals in Biology and Medicine", Chem. Soc. Rev. 2010, 39, 51-60. [pdf]




49. Dodani, S. C.; He, Q.; Chang, C. J. "A Turn-On Fluorescent Sensor for Detecting Nickel in Living Cells", J. Am. Chem. Soc. 2009, 131, 18020-18021. [pdf]




48. Soo, H. S.; Komor, A. C.; Iavarone, A. T.; Chang, C. J. "A Hydrogen-Bonded Facilitated Cycle for Oxygen Reduction by an Acid- and Base-Compatible Iron Platform", Inorg. Chem. 2009, 48, 10024-10035. [pdf]




47. Bao, L.; Avshalumov, M. V.; Miller, E. W.; Chang, C. J.; Rice, M. E. J. "Mitochondria are the Source of Hydrogen Peroxide for Dynamic Brain-Cell Signaling", J. Neurosci. 2009, 29, 9002-9010. [pdf]




46. Que, E. L.; Gianolio, E.; Baker, S. L.; Wong, A. P.; Aime, S.; Chang, C. J. "Copper-Responsive Magnetic Resonance Imaging Contrast Agents", J. Am. Chem. Soc. 2009, 131, 8527-8536. [pdf]




45. Albers, A. E.; Dickinson, B. C.; Miller, E. W.; Chang, C. J."A Red-Emitting Naphthofluorescein-Based Fluorescent Probe for Selective Detection of Hydrogen Peroxide in Living Cells", Bioorg. Med. Chem. Lett. 2008, 18, 5948-5950 (Special Issue in Honor of Benjamin F. Cravatt). [pdf]




44. Dickinson, B. C.; Chang, C. J."A Targetable Fluorescent Probe for Imaging Hydrogen Peroxide in the Mitochondria of Living Cells", J. Am. Chem. Soc. 2008, 130, 9638-9639. [pdf] [C&E News] [Angewandte Chemie Highlight]




43. Miller, E. W.; He, Q.; Chang, C. J. "Preparation and Use of Leadfluor-1, a Synthetic Fluorophore for Live-Cell Lead Imaging", Nature Protocols 2008, 3, 777-783. [pdf]




42. Que, E. L.; Domaille, D. W.; Chang, C. J. "Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging", Chem. Rev. 2008, 108, 1517-1549. [pdf]




41. Srikun, D.; Miller, E. W.; Domaille, D. W.; Chang, C. J."An ICT-Based Approach to Ratiometric Fluorescence Imaging of Hydrogen Peroxide Produced in Living Cells", J. Am. Chem. Soc. 2008, 130, 4596-4597. [pdf]




40. Domaille, D. W.; Que, E. L.; Chang, C. J. "Synthetic Fluorescent Sensors for Studying the Cell Biology of Metals", Nature Chem. Biol. 2008, 4, 168-175. [pdf]




39. Harman, W. H.; Chang, C. J. "N2O Activation and Oxidation Reactivity from a Non-Heme Iron Pyrrole Platform", J. Am. Chem. Soc. 2007, 129, 15128-15129. [pdf]




38. Miller, E. W.; Chang, C. J. "Fluorescent probes for nitric oxide and hydrogen peroxide in cell signaling" Curr. Opin. Chem. Biol. 2007, 11, 620-625. [pdf]




37. Albers, A. E.; Rawls, K. A.; Chang, C. J "Activity-based fluorescent reporters for monoamine oxidases in living cells", Chem. Commun. 2007, 4647-4649. [pdf]




36. Yoon, S.; Miller, E. W.; He, Q.; Do, P. H.; Chang, C. J "A Bright and Specific Fluorescent Sensor for Mercury in Water, Cells, and Tissue", Angew. Chem. Int. Ed. 2007, 46, 6658-6661. [pdf]




35. Miller, E. W.; Tulyathan, O.; Isacoff, E. Y.; Chang, C. J. "Molecular imaging of hydrogen peroxide produced for cell signaling", Nature Chem. Biol. 2007, 3, 263-267. [pdf] [C & E News]




34. Miller, E. W.; Bian, S. X.; Chang, C. J. "A Fluorescent Sensor for Imaging Reversible Redox Cycles in Living Cells", J. Am. Chem. Soc. 2007, 129, 3458-3459. [pdf]




33. Que, E. L.; Chang, C. J. "A Smart Magnetic Resonance Contrast Agent for Selective Copper Sensing", J. Am. Chem. Soc. 2006, 128, 15942-15943. [pdf]




32. Miller, E. W.; Zeng, L.; Domaille, D. W.; Chang, C. J. "Preparation and Use of Coppersensor-1, a Synthetic Fluorophore for Live-Cell Copper Imaging", Nature Protocols 2006, 1, 824-827. [pdf]




31. Albers, A. E.; Okreglak, V. S.; Chang, C. J. "A FRET-Based Approach to Ratiometric Fluorescence Detection of Hydrogen Peroxide", J. Am. Chem. Soc. 2006, 128, 9640-9641. [pdf]




30. He, Q.; Miller, E. W.; Wong, A. P.; Chang, C. J. "A Selective Fluorescent Sensor for Detecting Lead in Living Cells", J. Am. Chem. Soc. 2006, 128, 9316-9317. [pdf]




29. Zeng, L.; Miller, E. W.; Pralle, A.; Isacoff, E. Y.; Chang, C. J. "A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells", J. Am. Chem. Soc. 2006, 128, 10-11. [pdf]




28. Miller, E. W.; Albers, A. E.; Pralle, A.; Isacoff, E. Y.; Chang, C. J. "Boronate-Based Fluorescent Probes for Imaging Cellular Hydrogen Peroxide", J. Am. Chem. Soc. 2005, 127, 16652-16659. [pdf]




27. Yoon, S.; Albers, A. E.; Wong, A. P.; Chang, C. J. "Screening Mercury Levels in Fish with a Selective Fluorescent Chemosensor", J. Am. Chem. Soc. 2005, 127, 16030-16031. [pdf] [C&E News]




26. Chang, M. C. Y.; Pralle, A.; Isacoff, E. Y.; Chang, C. J. "A Selective, Cell-Permeable Optical Probe for Hydrogen Peroxide in Living Cells", J. Am. Chem. Soc. 2004, 126, 15392-15393. [html] [C&E News]





25. Chang, C. J.; Lippard, S. J. "Zinc Metalloneurochemistry: Physiology, Pathology, and Probes", In Metal Ions in Life Science: Neurodegenerative Diseases and Metal Ions. 2006, Vol. 1, pp. 321-370.

24. Giblin, L. J.; Chang, C. J.; Bentley, A. F.; Frederickson, C.; Lippard, S. J.; Frederickson, C. J. "Zinc-Secreting Paneth Cells Studied by ZP Fluorescence", J. Histochem. Cytochem. 2006, 54, 311-316.

23. Chang, C. J.; Nolan, E.M.; Jaworski, J.; Okamoto, K.; Hayashi, T.; Sheng, M.; Lippard, S.J. "ZP8, an Improved Neuronal Zinc Sensor of the ZP Family: Application to Imaging Zinc in Hippocampal Slices with Two-Photon Microscopy", Inorg. Chem. 2004, 43, 6774-6779.

22. Chang, C. J.; Loh, Z.-H.; Shi, C.; Anson, F.C. Nocera, D. G. "Targeted Proton Delivery in the Catalyzed Reduction of Oxygen to Water by Bimetallic Pacman Porphyrins", J. Am. Chem. Soc. 2004, 126, 10013-10020.

21. Chang, C. J.; Chang, M.C.Y.; Damrauer, N.H.; Nocera, D.G. "Proton-Coupled Electron Transfer. A Unifying Mechanism for Biological Charge Transport, Amino Acid Radical Initiation and Propagation, and Bond Making/Breaking Reactions of Water and Oxygen", Biochim. Biophys. Acta 2004, 1655, 13-28.

20. Chang, C. J.; Nolan, E.M.; Jaworski, J.; Burdette, S.C.; Sheng, M.; Lippard, S.J. "Bright Fluorescent Chemosensor Platforms for Imaging Endogenous Pools of Neuronal Zinc", Chem. Biol. 2004, 11, 203-210.

19. Chang, C. J.; Jaworski, J.; Nolan, E.M.; Sheng, M.; Lippard, S.J. "A Tautomeric Zinc Sensor for Ratiometric Fluorescence Imaging: Application to Nitric Oxide-Induced Release of Intracellular Zinc", Proc. Natl. Acad. Sci. USA 2004, 101, 1129-1134.

18. Hodgkiss, J.M.; Chang, C. J.; Pistorio, B.J.; Nocera, D. G. "Transient Absorption Studies of the Pacman Effect in Spring-Loaded Diiron(III) mu-Oxo Bisporphyrins", Inorg. Chem. 2003, 42, 8270-8277.

17. Chang, C. J.; Loh, Z.-H.; Deng, Y.; Nocera, D. G. "The Pacman Effect: A Supramolecular Strategy for Controlling the Excited-State Dynamics of Pillared Cofacial Bisporphyrins", Inorg. Chem. 2003, 42, 8262-8269.

16. Chng, L.-L.; Chang, C. J.; Nocera, D. G. "Meso-Tetraaryl Cofacial Bisporphyrins Delivered by Suzuki Cross-Coupling", J. Org. Chem. 2003, 68, 4075-4078.

15. Chng, L.-L.; Chang, C. J.; Nocera, D. G. "Catalytic O-O Activation Chemistry Mediated by Iron Hangman Porphyrins with a Wide Range of Proton-Donating Abilities", Org. Lett. 2003, 5, 2421-2424.

14. Chang, C. J.; Chng, L.-L.; Nocera, D. G. "Proton-Coupled O-O Activation on a Redox Platform Bearing a Hydrogen-Bonded Scaffold", J. Am. Chem. Soc. 2003, 125, 1866-1876.

13. Loh, Z.-H.; Miller, S. E.; Chang, C. J.; Carpenter, S. D.; Nocera, D. G. "Excited State Dynamics of Cofacial Pacman Porphyrins", J. Phys. Chem. A 2002, 106, 11700-11708.

12. Pistorio, B. J.; Chang, C. J.; Nocera, D. G. "A Phototriggered Molecular Spring for Aerobic Catalytic Oxidation Reactions", J. Am. Chem. Soc. 2002, 124, 7884-7885.

11. Chang, C. J.; Baker, E. A.; Pistorio, B. J.; Deng, Y.; Loh, Z.-H.; Miller, S. E.; Carpenter, S. D.; Nocera, D. G. "Structural, Spectroscopic, and Reactivity Comparison of Xanthene- and Dibenzofuran-Bridged Cofacial Bisporphyrins", Inorg. Chem. 2002, 41, 3102-3109.

10. Chang, C. J.; Deng, Y.; Lee, G.-H.; Peng, S.-M.; Yeh, C.-Y.; Nocera, D. G. "A Convergent Synthetic Approach Using Sterically Demanding Aryl-Dipyrrylmethanes for Tuning the Pocket Sizes of Cofacial Bisporphyrins", Inorg. Chem. 2002, 41, 3008-3016.

9. Chang, C. J.; Yeh, C.-Y.; Nocera, D. G. "Porphyrins Bearing Functionalized Xanthene Spacers", J. Org. Chem. 2002, 67, 1403-1406.

8. Chang, C. J.; Brown, J. D. K.; Chang, M. C. Y.; Baker, E. A.; Nocera, D. G. "Electron Transfer in Hydrogen-Bonded Donor-Acceptor Supramolecules", In Electron Transfer in Chemistry, V. Balzani Ed., Wiley-VCH, Weinheim, Germany, 2001, Vol. 3.2.4., p 409-461.

7. Yeh, C.-Y.; Chang, C. J.; Nocera, D. G. "'Hangman' Porphyrins for the Assembly of a Model Heme Water Channel", J. Am. Chem. Soc. 2001, 123, 1513-1514.

6. Chang, C. J.; Deng, Y.; Shi, C.; Chang, C. K.; Anson, F. C.; Nocera, D. G. "Electrocatalytic Four-Electron Reduction of Oxygen to Water by a Highly Flexible Cofacial Cobalt Bisporphyrin", Chem. Commun. 2000, 1355-1356.

5. Chang, C. J.; Deng, Y.; Heyduk, A. F.; Chang, C. K.; Nocera, D. G. "Xanthene-Bridged Cofacial Bisporphyrins", Inorg. Chem. 2000, 39, 959-966.

4. Deng, Y.; Chang, C. J.; Nocera, D. G. "Direct Observation of the 'Pac-Man' Effect from Dibenzofuran-Bridged Cofacial Bisporphyrins" J. Am. Chem. Soc. 2000, 122, 410-411.

3. Chang, C. J.; Connick, W. B.; Low, D. W.; Day, M. W.; Gray, H. B. "Electronic Structures of Nitridomanganese(V) Complexes", Inorg. Chem. 1998, 37, 3107-3110.

2. Chang, C. J.; Labinger, J. A.; Gray, H. B. "Aerobic Epoxidation of Olefins Catalyzed by Electronegative Vanadyl Salen Complexes", Inorg. Chem. 1997, 36, 5927-5930.

1. Chang, C. J.; Low, D. W.; Gray, H. B. "Reversible Nitrogen Atom Transfer between Nitridomanganese(V) and Manganese(III) Schiff-Base Complexes", Inorg. Chem. 1997, 36, 270-271.