Publications
242. Xie, X.; Jiang, Y.; Chang, C. J. "LOV thy neighbor: Mapping protein interactomes by genetically encodable photoproximity labeling",
PNAS
2023,
120, e2305211120.
[html] [pdf]
240. Washington-Hughes, C. L.; Roy, S.; Seneviratne, H. K.; Karuppagounder, S. S.; Morel, Y.; Jones, J. W.; Zak, A.; Xiao, T.; Boronina, T. N.; Cole, R. N.; Bumpus, N. N.; Chang, C. J; Dawson, T. M.; Lutsenko, S. "Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain", PLoS Genet. 2023, 19, e1010558. [html]
239. Jia, S.; Chang, C. J. "Chapter 3: Activity-based Sensing: Principles and Probes for Selective Bioimaging, in Fluorescent Chemosensors"; Editors: Wu, L.; Sedgwick, A. C.; He, X.-P.; James, T. D., Royal Society of Chemistry 2023. [html] [pdf]
238. Ge, E. J.; De La Torre, P.; Chang, C. J. "Chapter 19: Metals in Chemical Biology, in Advanced Chemical Biology: Chemical Dissection and Reprogramming of Biological Systems"; Editors: Hang, H. C.; Pratt, M. R.; Prescher, J. A., Wiley-VCH 2023. [html]
237.
Pham, V. N.; Chang, C. J. "Metalloallostery and Transition Metal Signalling: Bioinorganic Copper Chemistry Beyond Active Sites", Angew. Chem. Int. Ed.
2023,
6, e202213644.
[html] [pdf]
236. An, L.; De La Torre, P.; Smith, P. T.; Narouz, M. R.; Chang, C. J. "Synergistic Porosity and Charge Effects in a Supramolecular Porphyrin Cage Promote Efficient Photocatalytic CO2 Reduction",
Angew. Chem. Int. Ed.
2022,
e202209396.
[html] [pdf]
235.
Gonzalez-Valero, A.; Reeves, A. G.; Page, A. C. S.; Moon, P. J.; Miller, E.; Coulonval, K.; Crossley, S. W. M.; Xie, X.; He, D.; Musacchio, P. Z.; Christian, A. H.; McKenna, J. M.; Lewis, R. A.; Fang, E.; Dovala, D.; Yipin, L.; McGregor, L. M.; Schirle, M.; Tallarico, J. A.; Roger, P. P.; Toste, F. D., Chang, C. J. "An Activity-Based Oxaziridine Platform for Identifying and
Developing Covalent Ligands for Functional Allosteric Methionine
Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4",
J. Am. Chem. Soc.
2022,
144, 22890-22901.
[html] [pdf]
234.
Pezacki, A. T.; Matier, C. D.; Gu, X,; Kummelstedt, E.; Bond, S. E.; Torrente, L; Jordan-Sciutto, K. L.; DeNicola, G. M.; Su, T. A.; Brady, D. C.; Chang, C. J., "Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools",
PNAS
2022,
119, e2202736119.
[html] [pdf]
233.
Messina, M. S.; Quargnali, G.; Chang, C. J.; "Activity-Based Sensing for Chemistry-Enabled Biology: Illuminating Principles, Probes, and Prospects for Boronate Reagents for Studying Hydrogen Peroxide",
ACS Bio. Med. Chem. Au
2022,
2, 548-564.
[html] [pdf]
232.
Narouz, M. R.; De La Torre, P.; An, L.; Chang, C. J.; "Multifunctional Charge and Hydrogen-Bond Effects of Second-Sphere Imidazolium Pendants Promote Capture and Electrochemical Reduction of CO2 in Water Catalyzed by Iron Porphyrins",
Angew. Chem. Int. Ed.
2022,
61, e202207666.
[html] [pdf]
231.
De La Torre, P.; Derrick, J. S.; Snider, A.; Smith, P. T.; Loipersberger, M.; Head-Gordon, M.; Chang, C. J., "Exchange Coupling Determines Metal-Dependent Efficiency for Iron- and Cobalt-Catalyzed Photochemical CO2 Reduction",
ACS Catal.
2022,
12, 8484-8493.
[html] [pdf]
230.
Murphy, M. P.; Bayir, H.; Belousic, V.; Chang, C. J.; Davies, K. J. A.; Dabies, M. J.; Dick, T. P., Finkel; T., Forman, H. J.; Janssen-Heininger, Y.; Gems, D.; Kagan V. E.; Kalyanaraman, B.; Larsson, N.-G.; Milne, G. L.; Nystrom, T.; Poulsen, H. E.; Radi, R.; Van Remmen, H.; Schumacker, P. T.; Thornalley, P. J.; Toyokuni, S.; Winterbourn, C. C.; Yin, H.; Halliwell, B. "Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo",
Nat. Metab.
2022,
4, 651-662.
[html] [pdf]
229.
Derrick, J. S.; Loipersberger, M.; Nistanaki, S. K.; Rothweiler, A. V.; Head-Gordon, M.; Nichols, E. M.; Chang, C. J. "Templating Bicarbonate in the Second Coordination Sphere Enhances Electrochemical CO2 Reduction Catalyzed by Iron Porphyrins", J. Am. Chem. Soc.
2022,
144, 11656-11663.
[html] [pdf]
228.
He, D.; Feng, H.; Sundberg, B.; Yang, J.; Powers, J.; Christian, A. H.; Wilkinson, J. E.; Monnin, C.; Avizonis, D.; Thomas, C. J.; Freidman, R. A.; Kluger M. D.; Hollingsworth, M. A.; Grandgenett, P. M.; Klute, K. A.; Toste, D. F.; Chang, C. J; Chio, I. I. C. "Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis",
Mol. Cell
2022,
82, 3045-3060.e11.
[html] [pdf]
227.
Loipersberer, M.; Derrick J. S.; Chang, C. J.; Head-Gordon, M. "Deciphering Distinct Overpotential-Dependent Pathways for
Electrochemical CO2 Reduction Catalyzed by an Iron−Terpyridine
Complex",
Inorg. Chem.
2022,
61, 6919-6933.
[html] [pdf]
226.
Hoshi, K.; Messina, M. S.; Ohata, J.; Chung, C. Y.-S.; Chang, C. J. "A puromycin-dependent activity-based sensing
probe for histochemical staining of hydrogen
peroxide in cells and animal tissues",
Nat. Protoc.
2022,
17, 1691–1710.
[html] [pdf]
225.
Scrivner, O.; Dao, L.; Newell-Rogers, M. K.; Shahandeh, B.; Meyskens, F. L.; Kozawa, S. K.; Liu-Smith, F.; Plascencia-Villa, G.; José-Yacamán, M.; Jia, S.; Chang, C. J.; Farmer, P. J. "The ionophore thiomaltol induces rapid lysosomal accumulation of copper and apoptosis in melanoma",
Metallomics
2022,
14, mfab074.
[html] [pdf]
224.
Ge, E. J.; Bush, A. I.; Casini, A.; Cobine, P. A.; Cross, J. R.; DeNicola, G. M.; Dou, Q. P.; Franz, K. J.; Gohil, V. M.; Gupta, S.; Kaler, S. G.; Lutsenko, S.; Mittal, V.; Petris, M. J.; Polishchuk, R.; Ralle, M.; Schilsky, M. L.; Tonks, N. K.; Vahdat, L. T.; Aelst, L. V.; Xi, D.; Yuan, P.; Brady, D. C.; Chang, C. J. "Connecting copper and cancer: from transition metal signalling to metalloplasia",
Nat. Rev. Cancer
2022,
22,
102–113.
[html] [pdf]
223.
Sluysmans, S.; Méan, I.; Xiao, T.; Boukhatemi, A.; Ferreira, F.; Jond, L.; Mutero, A.; Chang, C. J.; Citi, S. "PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis",
Mol. Bio. Cell
2021,
32,
1–20.
[html] [pdf]
222.
Beavers, W. N.; DuMont, A. L.; Monteith, A. J.; Maloney, K. N.; Tallman, K. A.; Weiss, A.; Christian, A. H.; Toste, F. D.; Chang, C. J.; Porter, N. A.; Torres, V. J.; Skaar, E. P. "Staphylococcus aureus peptide methionine sulfoxide reductases protect from human whole blood killing",
Infect. Immun.
2021,
89,
IAI-00146.
[html] [pdf]
221.
Jia, S.; Chang, C. J. "A microtubule-localizing activity-based sensing fluorescent probe for imaging hydrogen peroxide in living cells",
Bioorg. Med. Chem. Lett.
2021,
48,
128252.
[html]
[pdf]
220.
Smith, P. T.; Benke, B. P.; An, L.; Kim, Y.; Kim, K.; Chang, C. J. "A Supramolecular Porous Organic Cage Platform Promotes Electrochemical Hydrogen Evolution from Water Catalyzed by Cobalt Porphyrins",
ChemElectroChem
2021,
8,
1653–1657.
[html]
[pdf]
219.
Wuttig, A.; Derrick, J. S.; Loipersberger, M.; Snider, A.; Head-Gordon, M.; Chang, C. J.; Toste, D. "Controlled Single-Electron Transfer via Metal−Ligand Cooperativity Drives Divergent Nickel-Electrocatalyzed Radical Pathways",
J. Am. Chem. Soc.
2021,
143, 6990-7001.
[html]
[pdf]
218.
Iwashita, H.; Castillo, E.; Messina, M. S.; Swanson, R.A.; Chang, C. J. "A tandem activity-based sensing and labeling strategy enables imaging of transcellular hydrogen peroxide signaling",
PNAS
2021,
118,
e2018513118.
[html]
[pdf]
217.
Kim J. H.; Matsubara T.; Lee J.; Fenollar-Ferrer C.; Han K.; Kim D.; Jia S.; Chang C. J.; Yang H.; Nagano T.; Krausz K.W. "Lysosomal SLC46A3 modulates hepatic cytosolic copper homeostasis",
Nat. Commun.
2021,
12,
1–12.
[html]
[pdf]
216.
Wang, Z.; Detomasi, T. C.; Chang, C. J. "A dual-fluorophore sensor approach for ratiometric fluorescence imaging of potassium in living cells",
Chem. Sci.
2021,
12,
1720-1729.
[html]
[pdf]
215.
Mao, Y.; Loipersberger, M.; Kron, K. J.; Derrick, J. S.; Chang, C. J.; Sharada, S. M.; Head-Gordon, M.
"Consistent inclusion of continuum solvation in energy decomposition analysis: theory and application to molecular CO2 reduction catalysts",
Chem. Sci.
2021,
12,
1398–1414.
[html]
[pdf]
214.
Shen, X.; Wang, R.; Kim, M. J.; Hu, Q.; Hsu, C.; Yao, J.; Klages-Mundt, N.; Tian, Y. Lynn, E.; Brewer, T. F.; Zhang, Y.; Arun, B.; Gan, B.; Andreeff, M.; Takeda, S.; Chen, J.; Park, J.; Shi, X.; Chang, C. J.; Jung, S. Y.; Qin, J.; Li, L. "A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia",
Mol. Cell
2020.
80,
1013-1024.
[html]
[pdf]
213.
Derrick, J. S., Loipersberger, M.; Chatterjee, R.; Iovan, D. A.; Smith, P. T.; Chakarawet, K.; Yano, J.; Long, J. R.; Head-Gordon, M.; Chang, C. J. "Metal–Ligand Cooperativity via Exchange Coupling Promotes Iron- Catalyzed Electrochemical CO2 Reduction at Low Overpotentials",
J. Am. Chem. Soc.
2020,
142, 20489–20501.
[html]
[pdf]
212.
Amor, M.; Ceballos, A.; Wan, J.; Simon, C. P.; Aron, A. T.; Chang, C. J.; Hellman, F.; Komeili, A. "Magnetotactic Bacteria Accumulate a Large Pool of Iron Distinct from Their Magnetite Crystals",
Appl. Environ. Microbiol.
2020,
86,
e01278–20.
[html]
[pdf]
211.
Zhao, Y.; Wei, L.; Tagmount, A.; Loguinov, A.; Sobh, A.; Hubbard, A.; McHale, C. M.; Chang, C. J.; Vulpe, C. D.; Zhang, L. "Applying Genome-wide CRISPR to Identify Known and Novel Genes and Pathways that Modulate Formaldehyde Toxicity",
Chemosphere
2020,
128701.
[html]
210.
Toh, J. D. W.; Crossley, S. W. M.; Bruemmer, K. J.; Ge, E. J.; He, D.; Iovan, D. A.; Chang, C. J. "Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates",
PNAS
2020,
117,
25284-25292.
[html]
[pdf]
209.
Morstein, J.; Höfler, D.; Ueno, K.; Jurss, J. W.; Walvoord, R. R.; Bruemmer, K. J.; Rezgui, S. P.; Brewer, T. F.; Saitoe, M.; Michel, B. W.; Chang, C. J. "Ligand-Directed Approach to Activity-Based Sensing: Developing Palladacycle Fluorescent Probes That Enable Endogenous Carbon Monoxide Detection",
J. Am. Chem. Soc.
2020,
142,
15917–15930.
[html]
[pdf]
208.
Lee, S.; Chung, C. Y.-S.; Liu, P., Craciun, L; Nishikawa, Y.; Bruemmer, K. J.; Hamachi, I.; Saijo, K.; Miller, E. W.; Chang, C. J. "Activity-Based Sensing with a Metal-Directed Acyl Imidazole Strategy Reveals Cell Type-Dependent Pools of Labile Brain Copper",
J. Am. Chem. Soc.
2020,
142,
14993–15003.
[html]
[pdf]
207.
Bruemmer, K. J.;
Crossley, S. W. M.;
Chang, C. J.
"Activity-Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond",
Angew. Chem. Int. Ed.
2020,
59,
13734–13762.
[html]
[pdf]
206.
Proppe, A. H.; Li, Y. C.; Aspuru-Guzik, A.; Berlinguette, C. P.; Chang, C. J.; Cogdell, R.; Doyle, A. G.; Flick, J.; Gabor, N. M.; van Grondelle, R.; Hammes-Schiffer, S.; Jaffer, S. A.; Kelley, S. O.; Leclerc, M.; Leo, K.; Mallouk, T. E.; Narang, P.; Schlau-Cohen, G. S.; Scholes, G. D.; Vojvodic, A.; Yam, V. W.-W.; Yang, J. Y.; Sargent, E. H.
"Bioinspiration in light harvesting and catalysis",
Nat. Rev. Mater.
2020,
59,
1–19.
[html]
[pdf]
204. Loipersberger, M.; Zee, D. Z.; Panetier, J. A.; Chang, C. J.; Long, J. R.; Head-Gordon, M. "Computational Study of an Iron(II) Polypyridine Electrocatalyst for CO2 Reduction: Key Roles for Intramolecular Interactions in CO2 Binding and Proton Transfer" Inorg. Chem. 2020, 59, 8146–8160. DOI: 10.1021/acs.inorgchem.0c00454 [html] [pdf]
203.
Protchenko, O.; Baratz, E.; Jadhav, S.; Li, F.; Shakoury-Elizeh, M.; Gavrilova, O.; Ghosh, M. C.; Cox, J. E.; Maschek, J. A.; Tyurin, V. A.; Tyurina, Y. Y.; Bayir, H.; Aron, A. T.; Chang, C. J.; Kagan, V. E.; Philpott, C. C.
"Iron chaperone PCBP1 protects murine liver from lipid peroxidation and steatosis,"
Hepatology
2020,
DOI: 10.1002/hep.31328
[html]
[pdf]
202.
Ueno, K.; Morstein, J.; Ofusa, K.; Naganos, S.; Suzuki-Sawano, E.; Minegishi, S.; Rezgui, S. P.; Kitagishi, H.; Michel, B. W.; Chang, C. J.; Horiuchi, J.; Saitoe, M.
"Carbon Monoxide, a Retrograde Messenger Generated in Postsynaptic Mushroom Body Neurons, Evokes Noncanonical Dopamine Release,"
J. Neurosci.
2020,
40, 3533–3548.
[html]
[pdf]
201.
Zee, D. Z.;
Nippe, M.;
King, A. E.;
Chang, C. J.;
Long, J. F.
"Tuning Second Coordination Sphere Interactions in Polypyridyl-Iron Complexes to Achieve Selective Electrocatalytic Reduction of Carbon Dioxide to Carbon Monoxide,"
Inorg. Chem.
2020,
59, 5206–5217.
[html]
[pdf]
200.
Smith, P. T,;
Nichols, E. M.;
Cao, Z.;
Chang, C. J.
"Hybrid Catalysts for Artificial Photosynthesis: Merging Approaches from Molecular, Materials, and Biological Catalysis",
Acc. Chem. Res.
2020,
53, 575–587.
[html]
[pdf]
199.
Elledge, S. K.;
Tran, H. L.;
Christian, A. H.;
Steri, V.;
Hann, B.;
Toste, F. D.;
Chang, C. J.;
Wells, J. A.
"Systematic identification of engineered methionines and oxaziridines for efficient, stable, and site-specific antibody bioconjugation",
Proc. Natl. Acad. Sci. USA
2020,
117, 5733–5740.
[html]
[pdf]
198.
Venkatesh, D.;
O'Brien, N. A,;
Zandkarimi, F.;
Tong, D. R.;
Stokes, M. E.;
Dunn, D. E.;
Kengmana, E.S.;
Aron, A. T.;
Klein, A. M.;
Csuka, J. M.;
Moon, S. H.;
Conrad, M.;
Chang, C. J.;
Lo, D. C.;
D'Alessandro, A.;
Prives, C.;
Stockwell, B. R.
"MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling",
Genes Dev.
2020,
34, 526–543.
[html]
[pdf]
197.
Liao, Y.;
Zhao, J.;
Bulek, K.;
Tang, F.;
Chen, X.;
Cai, G.;
Jia, S.;
Fox, P. L.;
Huang, E.;
Pizarro, T. T.;
Kalady, M. F.;
Jackson, M. W.;
Bao, S.;
Sen, G. C.;
Stark, G. R.;
Chang, C.J.;
Li, X.
"Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis",
Nat. Commun.
2020,
11,
900.
[html]
[pdf]
196.
Ohata, J.;
Krishnamoorthy, L.;
Gonzalez, M. A.;
Xiao, T.;
Iovan, D. A.;
Toste, F. D.;
Miller, E. W.;
Chang, C. J.
"An Activity-Based Methionine Bioconjugation Approach To Developing Proximity-Activated Imaging Reporters",
ACS Cent. Sci.
2020,
6,
32-40.
[html]
[pdf]
195.
Smith, P. T.;
Kim, Y.;
Benke, B. P.;
Kim, K.;
Chang, C. J.
"Supramolecular Tuning Enables Selective Oxygen Reduction Catalyzed by Cobalt Porphyrins for Direct Electrosynthesis of Hydrogen Peroxide",
Angew. Chemie. Int. Ed.
2020,
59,
4902-4907.
[html]
[pdf]
194.
Huff, T. C.;
Camarena, V.;
Sant, D. W.;
Wilkes, Z.;
Van Booven, D.;
Aron, A. T.;
Muir, R. K.;
Renslo, A. R.;
Chang, C. J.;
Monje, P. V.;
Wang, G.
"Oscillatory cAMP signaling rapidly alters H3K4 methylation.",
Life Sci. Alliance
2019,
3,
e201900529.
[html]
[pdf]
193.
Ohata, J.;
Bruemmer, K. J.;
Chang, C. J.
"Activity-Based Sensing Methods for Monitoring the Reactive Carbon Species Carbon Monoxide and Formaldehyde in Living Systems",
Acc. Chem. Res.
2019,
52,
2841-2848.
[html]
[pdf]
192.
Chung, C. Y.;
Posimo, J. M.;
Lee, S.;,
Tsang, T.;
Davis, J. M.;
Brady, D. C.;
Chang, C. J.
"Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism",
Proc. Natl. Acad. Sci. USA
2019,
116,
18285-18294.
[html]
[pdf]
191.
Christian, A. H.;
Jia, S.;
Cao, W.;
Zhang, P.;
Meza, A. T.;
Sigman, M. S.;
Chang, C. J.;
Toste, F. D.
"A Physical Organic Approach to Tuning Reagents for Selective andStable Methionine Bioconjugation",
J. Am. Chem. Soc.
2019,
141,
12657-12662.
[html]
[pdf]
190.
Su, T. A.;
Bruemmer, K. J.;
Chang, C. J.;
"Caged luciferins for bioluminescent activity-based sensing",
Curr. Opin. Biotechnology
2019,
60,
198-204.
[html]
[pdf]
189.
Iovan, D. A.;
Jia, S.;
Chang, C. J.;
"Inorganic Chemistry Approaches to Activity-Based Sensing: From Metal Sensors to Bioorthogonal Metal Chemistry",
Inorg Chem
2019,
58,
13546-13560.
[html]
[pdf]
188.
Lee, S.;
Uliana, A.;
Taylor, M. K.;
Chakarawet, K.;
Rama, S.;
Bandaru, S.;
Gul, S.;
Xu, J.;
Ackerman, C. M.;
Chatterjee, R.;
Furukawa, H.;
Reimer, J. A.;
Yano, J.;
Gadgil, A.;
Long, G. J.;
Grandjean, F.;
Long, J. R.;
Chang, C. J.;
Iron detection and remediation with a functionalized porous polymer applied to environmental water sample",
Chem. Sci.
2019,
10,
6651.
[html]
[pdf]
187.
Baldari, S.;
Di Rocco, G.;
Heffern, M. C.;
Su, T. A.;
Chang, C. J.;
Toietta, G.
"Effects of Copper Chelation on BRAFV600E Positive Colon Carcinoma Cells",
Cancers
2019,
11,
659.
[html]
186.
Jia, S.;
He, D.;
Chang, C. J.;
"Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation",
J. Am. Chem. Soc.
2019,
141,
7294-7301.
[html]
[pdf]
185.
Su, T. A.;
Shihadih, D. A.;
Cao, w.;
Detomasi, T. C..;
Heffern, M. C.;
Jia, S.;
Stahl, A.;
Chang, C. J.;
"A Modular Ionophore Platform for Liver-Directed Copper Supplementation in Cells and Animals",
J. Am. Chem. Soc.
2018,
140,
13764-13774.
[html]
[pdf]
[JACS Spotlights]
183. Nichols, E. M.; Chang, C. J.; "Urea-Based Multipoint Hydrogen-Bond Donor Additive Promotes Electrochemical CO2 Reduction Catalyzed by Nickel Cyclam", Organometallics 2018, 38, 1213-1218. [html] [pdf]
182.
Smith, P. T.;
Benke, B. P.;
Cao, Z.;
Kim, Y.;
Nichols, E. M.;
Kim, K.;
Chang, C. J.;
"Iron Porphyrins Embedded into a Supramolecular Porous Organic Cage for Electrochemical CO2 Reduction in Water",
Angew. Chem. Int. Ed.
2018,
57,
9684-9688.
[html]
[pdf]
181.
Krishnamoorthy, L.;
Chang, C. J.;
"Exosomal NADPH Oxidase: Delivering Redox Signaling for Healing",
Biochemistry
2018,
57,
3993-3994.
[html]
[pdf]
180.
Xiao, T.;
Ackerman, C. M.;
Carroll, E. C.;
Jia, S.;
Hoagland, A.;
Chan, J.;
Thai, B.;
Liu, C. S.;
Isacoff, E. Y.;
Chang, C. J.;
"Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system",
Nature Chem. Biol.
2018,
14,
655-663.
[html]
[pdf]
[C&EN]
[HWNI]
179.
Chung, C. Y. S.;
Timblin, G. A.;
Saijo, K.;
Chang, C. J.;
"Versatile Histochemical Approach to Detection of Hydrogen Peroxide in Cells and Tissues Based on Puromycin Staining",
J. Am. Chem. Soc.
2018,
140,
6109-6121.
[html]
[pdf]
178.
Bruemmer, K. J.;
Green, O.;
Su, T. A.;
Shabat, D.;
Chang, C. J.;
"Chemiluminescent Probes for Activity-Based Sensing of Formaldehyde Released from Folate Degradation in Living Mice",
Angew. Chem. Int. Ed.
2018,
57,
7508-7512.
[html]
[pdf]
176.
Cao, Z.*;
Derrick, J. S.*;
Xu, J.*;
Gao, R.;
Gong, M.;
Nichols, E. M.;
Smith, P. T.;
Liu, X.;
Wen, X.;
Coperet, C.;
Chang, C. J.;
"Chelating N-Heterocyclic Carbene Ligands Enable Tuning of Electrocatalytic CO2 Reduction to Formate and Carbon Monoxide through Surface Organometallic Chemistry",
Angew. Chem. Int. Ed.
2018,
57,
4981-4985.
[html]
[pdf]
175.
Nichols, E. M.*;
Derrick, J. S.*;
Nistanaki, S. K.;
Smith, P. T.;
Chang, C. J.;
"Positional effects of second-sphere amide pendants on electrochemical CO2 reduction catalyzed by iron porphyrins",
Chem. Sci.
2018,
9,
2952-2960.
[html]
[pdf]
174.
Jia, S.*;
Ramos-Torres, K. M.*;
Kolemen, S.;
Ackerman, C. M.;
Chang, C. J.;
"Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores",
ACS Chem. Biol.
2018,
13,
1844-1852.
[html]
[pdf]
173.
Diercks, C. S.;
Lin, S.;
Kornienko, N.;
Kapustin, E. A.;
Nichols, E. M.;
Zhu, C.;
Zhao, Y.;
Chang, C. J.;
Yaghi. O. M.
"Reticular Electronic Tuning of Porphyrin Active Sites in Covalent Organic Frameworks for Electrocatalytic Carbon Dioxide Reduction",
J. Am. Chem. Soc.
2018,
140,
1116-1122.
[html]
[pdf]
172.
Aron, A. T.;
Reeves, A. G.;
Chang, C. J.;
"Activity-based sensing fluorescent probes for iron in biological systems",
Curr. Opin. Chem. Biol.
2018,
43,
113-118.
[html]
[pdf]
171.
Camarena, V.;
Sant, D. W.;
Huff, T. C.;
Mustafi, S.;
Muir, R. K,;
Aron, A. T.;
Chang, C. J.;
Renslo, A. R.;
Monje, P. V.;
Wang, G.;
"cAMP signaling regulates DNA hydroxymethylation by augmenting the intracellular labile ferrous iron pool",
eLIFE
2017,
6,
e29750.
[html]
170.
Ackerman, C. M.;
Chang, C. J.;
"Copper Signaling in the Brain and Beyond",
J. Biol. Chem.
2017,
293,
4628-4635.
[html]
169.
Aron, A. T.*;
Heffern, M. C.*;
Lonergan, Z. R.*;
Vander Wal, M. N.;
Blank, B. R.;
Spangler, B.;
Zhang, Y.;
Park, H. M.;
Stahl, A.;
Renslo, A. R.;
Skaar, E. P.;
Chang, C. J.;
"In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection",
Proc. Natl. Acad. Sci. USA
2017,
114,
12669–12674.
[html]
[pdf]
168.
Gong, M.*;
Cao, Z.*;
Liu, W.*;
Nichols, E. M.;
Smith, P. T.;
Derrick, J. S.;
Liu, Y. S.;
Liu, J.;
Wen, X.;
Chang, C. J.;
"Supramolecular Porphyrin Cages Assembled at Molecular–Materials Interfaces for Electrocatalytic CO Reduction",
ACS Cent. Sci.
2017,
3,
1032-1040.
[html]
[pdf]
167.
Burgos-Barragan, G.;
Wit, N.;
Meiser, J.;
Dingler, F. A.;
Pietzke, M.;
Mulderrig, L.;
Pontel, L. B.;
Rosado, I. V.;
Brewer, T. F.;
Cordell, R. L.;
Monks, P. S.;
Chang, C. J.;
Vazquez, A.;
Patel, K. J.
"Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism",
Nature
2017,
548,
549-554.
[html]
[pdf]
166.
Bruemmer, K. J.*;
Brewer, T. F.*;
Chang, C. J.
"Fluorescent probes for imaging formaldehyde in biological systems",
Curr. Opin. Chem. Biol.
2017,
39,
17-23.
[html]
[pdf]
165.
Brewer, T. F.;
Burgos-Barragan, G.;
Wit, N.;
Patel, K. J.;
Chang, C. J.
"A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in living cells",
Chem. Sci.
2017,
8,
4073-4081.
[html]
[pdf]
164.
Bruemmer, K. J.*;
Walvoord, R. R.*;
Brewer, T. F.;
Burgos-Barragan, G.;
Wit, N.;
Pontel, L. B.;
Patel, K. J.;
Chang, C. J.
"Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde in Living Cells",
J. Am. Chem. Soc.
2017,
139,
5338-5350.
[html]
[pdf]
163.
Chang, C. J.
"Bioinorganic Life and Neural Activity: Toward a Chemistry of Consciousness?",
Acc. Chem. Res.
2017,
50,
535-538.
[html]
[pdf]
162.
Lin, S.;
Yang, X.;
Jia, S.;
Weeks, A. M.;
Hornsby, M.;
Lee, P. S.;
Nichiporuk, R. V.;
Iavarone, A. T.;
Wells, J. A.;
Toste, F. D.;
Chang, C. J.
"Redox-based reagents for chemoselective methionine bioconjugation",
Science
2017,
355,
597-602.
[html]
[pdf]
[C&E News]
[Berkeley Lab]
[Phys. Org]
[In the Pipeline]
[ACS Chem. Biol.]
[F1000]
161.
Ackerman, C. M.;
Lee, S.;
Chang, C. J.
"Analytical Methods for Imaging Metals in Biology: From Transition Metal Metabolism to Transition Metal Signaling",
Anal. Chem.
2017,
89,
22-41.
[html]
[pdf]
160.
Heffern, M. C.;
Park, H. M.;
Au-Yeung, H. Y.;
Van de Bittner, G. C.;
Ackerman, C. M.;
Stahl, A.
Chang, C. J.
"In vivo bioluminescence imaging reveals copper deficiency in a murine model of nonalcoholic fatty liver disease",
Proc. Natl. Acad. Sci. USA
2016,
113,
14219-14224.
[html]
[pdf]
159.
Kashif, M. K.;
Milhuisen, R. A.;
Nippe, M.;
Hellerstedt, J.;
Zee, D. Z.;
Duffy, N. W.;
Halstead, B.;
De Angelis, F.;
Fantacci, S.;
Fuhrer, M. S.;
Chang, C. J.;
Cheng, Y.-B.;
Long, J. R.;
Spiccia, L.;
Bach, U.
"Cobalt Polypyridyl Complexes as Transparent Solution-Processable Solid-State Charge Transport Materials",
Adv. Energy Mater.
2016,
1600874.
[html]
[pdf]
158.
Aron, A. T.;
Loehr, M. O.;
Bogena, J.;
Chang, C. J.
"An Endoperoxide Reactivity-Based FRET Probe for Ratiometric Fluorescence Imaging of Labile Iron Pools in Living Cells",
J. Am. Chem. Soc.
2016,
138,
14338-14346.
[html]
[pdf]
157.
Rodella, U.;
Scorzeto, M.;
Duregotti, E.;
Negro, S.;
Dickinson, B. C.;
Chang, C. J.;
Yuki, N.;
Rigoni, M.;
Montecucco, C.
"An animal model of Miller Fisher syndrome: Mitochondrial hydrogen peroxide is produced by the autoimmune attack of nerve terminals and activates Schwann cells",
Neurobiol. Dis.
2016,
96,
95-104.
[html]
[pdf]
156.
Cox, A. G.;
Tsomides, A.;
Kim, A. J.;
Saunders, D.;
Hwang, K. L.;
Evason, K. J.;
Heidel, J.;
Brown, K. K.;
Yuan, M.;
Lien, E. C.;
Lee, B. C.;
Nissim, S.;
Dickinson, B. C.;
Chhangawala, D.;
Chang, C. J.;
Asara, J. M.;
Houvras, Y.;
Gladyshev, V. N.;
Goessling, W.
"Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis",
Proc. Natl. Acas. Sci. U. S. A.
2016,
113,
E5562-E5571.
[html]
[pdf]
155.
Ramos-Torres, K. M.;
Kolemen, S.;
Chang, C. J.
"Thioether Coordination Chemistry for Molecular Imaging of Copper in Biological Systems",
Isr. J. Chem.
2016,
56,
724-737.
[html]
[pdf]
154.
Axelson, J. C.;
Gonzalez, M. I.;
Meihaus, K. R.;
Chang, C. J.;
Long, J. R.
"Synthesis and Characterization of a Tetrapodal NO44- Ligand and Its Transition Metal Complexes",
Inorg. Chem.
2016,
55,
7527-7534.
[html]
[pdf]
153.
Spangler, B.;
Morgan, C. W.;
Fontaine, S. D.;
Vander Wal, M. N.;
Chang, C. J.;
Wells, J. A.;
Renslo, A. R.
"A reactivity-based probe of the intracellular labile ferrous iron pool",
Nature Chem. Biol.
2016,
12,
680-685.
[html]
[pdf]
152.
Cao, Z.;
Kim, D.;
Yu, Y.;
Xu, J.;
Lin, S.;
Wen, X.;
Nichols, E. M.;
Jeong, K.;
Reimer, J. A.;
Yang, P.;
Chang, C. J.
"A Molecular Surface Functionalization Approach to Tuning Nanoparticle Electrocatalysts for Carbon Dioxide Reduction",
J. Am. Chem. Soc.
2016,
138,
8120-8125.
[html]
[pdf]
151.
Lee, S.;
Barin, G.;
Ackerman, C. M.;
Muchenditsi, A.;
Xu, J.;
Reimer, J. A.;
Lutsenko, S.;
Long, J. R.;
Chang, C. J.
"Copper Capture in a Thioether-Functionalized Porous Polymer Applied to the Detection of Wilson's Disease",
J. Am. Chem. Soc.
2016,
138,
7603-7609.
[html]
[pdf]
150.
Krishnamoorthy, L.;
Cotruvo, Jr., J. A.;
Chan, J.;
Kaluarachchi, H.;
Muchenditsi, A.;
Pendyala, V. S.;
Jia, S.;
Aron, A. T.;
Ackerman, C. M.;
Vander Wal, M. N.;
Guan, T.;
Smaga, L. P.;
Farhi, S. L.;
New, E. J.;
Lutsenko, S.;
Chang, C. J.
"Copper regulates cyclic-AMP-dependent lipolysis",
Nature Chem. Biol.
2016,
12,
586-592.
[html]
[pdf]
[Biomedical Beat Story]
[UC Science Today Segment]
[PictureFit YouTube Video]
[LBNL News Story]
[UC Berkeley News Story]
[Daily Mail News Story]
[Genetic Engineering and Biotechnology News Story]
[Dr Oz Reviews Story]
[Men's Fitness Story]
[Deccan Herald News Story]
[Fitness First Mag Story]
[Indo Asian News Service Story]
[Health Canal News Story]
[First Post News Story]
[Business Standard News Story]
[The Health Site News Story]
[Hindustan Times News Story]
[Can-India News Story]
[Natural Science News Story]
[Times of India News Story]
[Money Control News Story]
[American Council on Science and Health News Story]
[China Topix News Story]
[MSN News Story]
[Press Liberal News Story]
[Headlines News Story]
[The Sentinel News Story]
[Brief Report News Story]
[Engine News Story]
[3 Novices News Story]
[HT Syndication News Story]
[New York Indian News Story]
149.
Liu, W.;
Truillet, C.;
Flavell, R. R.;
Brewer, T. F.;
Evans, M. J.;
Wilson, D. M.;
Chang, C. J.
"A reactivity-based [18F]FDG probe for in vivo formaldehyde imaging using positron emission tomography",
Chem. Sci.
2016,
7,
5503-5507.
[html]
[pdf]
148.
Tomalin, L. E.;
Day, A. M.;
Underwood, Z. E.;
Smith, G. R.;
Pezze, P. D.;
Rallis, C.;
Patel, W.;
Dickinson, B. C.;
Bahler, J.;
Brewer, T. F.;
Chang, C. J.;
Shanley, D. P.;
Veal, E. A.
"Increasing extracellular H2O2 produces a bi-phasic response in intracellular H2O2, with peroxiredoxin hyperoxidation only triggered once the cellular H2O2-buffering capacity is overwhelmed",
Free Radic. Biol. Med.
2016,
95,
333-348.
[html]
[pdf]
147.
Flavell, R. R.;
Truillet, C.;
Regan, M. K.;
Ganguly, T.;
Blecha, J. E.;
Kurhanewicz, J.;
VanBrocklin, H. F.;
Keshari, K. R.;
Chang, C. J.;
Evans, M. J.;
Wilson, D. M.
"Caged [18F]FDG Glycosylamines for Imaging Acidic Tumor Microenvironments Using Positron Emission Tomography",
Bioconjugate Chem.
2016,
27,
170-178.
[html]
[pdf]
146.
Kornienko, N.;
Zhao, Y.;
Kley, C. S.;
Zhu, C.;
Kim, D.;
Lin, S.;
Chang, C. J.;
Yaghi, O. M.;
Yang, P.
"Metal–Organic Frameworks for Electrocatalytic Reduction of Carbon Dioxide",
J. Am. Chem. Soc.
2015,
137,
14129-14135.
[html]
[pdf]
145.
Chang, C. J.
"Searching for Harmony in Transition-Metal Signaling",
Nature Chem. Biol.
2015,
111,
744-747.
[html]
[pdf]
144.
Brewer, T. F.;
Chang, C. J.
"An Aza-Cope Reactivity-Based Fluorescent Probe for Imaging Formaldehyde in Living Cells",
J. Am. Chem. Soc.
2015,
37,
10886-10889.
[html]
[pdf]
[Chemical & Engineering News Story]
143.
Nichols, E. M.;
Gallagher, J. J.;
Liu, C.;
Su, Y.;
Resasco, J.;
Yu, Y.;
Sun, Y.;
Yang, P.;
Chang, M. C. Y.;
Chang, C. J.
"Hybrid bioinorganic approach to solar-to-chemical conversion",
Proc. Natl. Acad. Sci. USA
2015,
112,
11461-11466.
[html]
[pdf]
[LBNL News Story]
[ScienceDaily News Story]
[Demanjo News Story]
[Science Newsline News Story]
[Tech News Coverage News Story]
[Adaptive Scientist News Story]
[Guldar News Story]
[DOE Science Headlines]
142.
Lin, S.;
Diercks, C. S.;
Zhang, Y.;
Kornienko, N.;
Nichols, E. M.;
Zhao, Y.;
Paris, A. R.;
Kim, D.;
Yang, P.;
Yaghi, O. M.;
Chang, C. J.
"Covalent organic frameworks comprising cobalt porphyrins for catalytic CO2 reduction in water",
Science
2015,
346,
1208-1213.
[html]
[pdf]
[LBNL News Story]
[Science News Story]
141.
Aron, A. T.;
Ramos-Torres, K. M.;
Cotruvo, Jr., J. A.;
Chang, C. J.
"Recognition- and Reactivity-Based Fluorescent Probes for Studying Transition Metal Signaling in Living Systems",
Acc. Chem. Res.
2015,
48,
2434-2442.
[html]
[pdf]
140.
Zee, D. Z.;
Chantarojsiri, T.;
Long, J. R.;
Chang, C. J.
"Metal-Polypyridyl Catalysts for Electro- and Photochemical Reduction of Water to Hydrogen",
Acc. Chem. Res.
2015,
48,
2027-2036.
[html]
[pdf]
139.
Jurss, J. W.;
Khnayzer, R. S.;
Panetier, J. A.;
El Roz, K. A.;
Nichols, E. M.;
Head-Gordon, M.;
Long, J. R.;
Castellano, F. N.;
Chang, C. J.
"Bioinspired design of redox-active ligands for multielectron catalysis: effects of positioning pyrazine reservoirs on cobalt for electro- and photocatalytic generation of hydrogen from water",
Chem. Sci.
2015,
6,
4954-4972.
[html]
[pdf]
138.
Chantarojsiri, T.;
Sun, Y.;
Long, J. R.;
Chang, C. J.
"Water-Soluble Iron(IV)-Oxo Complexes Supported by Pentapyridine Ligands: Axial Ligand Effects on Hydrogen Atom and Oxygen Atom Transfer Reactivity",
Inorg. Chem.
2015,
54,
5879-5887.
[html]
[pdf]
137.
Brewer, T. F.;
Garcia, F. J.;
Onak, C. S.;
Carroll, K. S.;
Chang, C. J.
"Chemical Approaches to Discovery and Study of Sources and Targets of Hydrogen Peroxide Redox Signaling Through NADPH Oxidase Proteins",
Annu. Rev. Biochem.
2015,
84,
765-790.
[html]
[pdf]
136.
Liu, C.;
Gallagher, J. J.;
Sakimoto, K. K.;
Nichols, E. M.;
Chang, C. J.;
Chang, M. C. Y.;
Yang, P.
"Nanowire–Bacteria Hybrids for Unassisted Solar Carbon Dioxide Fixation to Value-Added Chemicals",
Nano Lett.
2015,
15,
3634-3639.
[html]
[pdf]
[LBNL News Story]
[Tech Times News Story]
[Science Times News Story]
[News Everyday News Story]
[DOE Science Headline]
[Huffington Post article]
[Statesman article]
135.
Lin, V. S.;
Lippert, A. R.;
Chang, C. J.
"Azide-Based Fluorescent Probes: Imaging Hydrogen Sulfide in Living Systems",
Meth. Enzymol.
2015,
554,
63-80
(Chapter 4 in Hydrogen Sulfide in Redox Biology, Part A).
[html]
[pdf]
134.
Fu, X.;
Tang, Y.;
Dickinson, B. C.;
Chang, C. J.;
Chang, Z.
"An oxidative fluctuation hypothesis of aging generated by imaging H2O2 levels in live Caenorhabditis elegans with altered lifespans",
Biochem. Biophys. Res. Commun.
2015,
458,
896-900.
[html]
[pdf]
133.
Cotruvo, Jr., J. A.;
Aron, A. T.;
Ramos-Torres, K. M.;
Chang, C. J.
"Synthetic fluorescent probes for studying copper in biological systems",
Chem. Soc. Rev.
2015,
44,
4400-4414.
[html]
[pdf]
132.
Lin, V. S.;
Chen, W.;
Xian, M.;
Chang, C. J.
"Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems",
Chem. Soc. Rev.
2015,
44,
4596-4618.
[html]
[pdf]
131.
Duregotti, E.;
Negro, S.;
Scorzeto, M.;
Zornetta, I.;
Dickinson, B. C.;
Chang, C. J.;
Montecucco, C.;
Rigoni, M.
"Mitochondrial alarmins released by degenerating motor axon terminals activate perisynaptic Schwann cells",
Proc. Natl. Acad. Sci. USA
2015,
112,
E497-E505.
[html]
[pdf]
130.
Dodani, S. C.;
Firl, A.;
Chan, J.;
Nam, C. I.;
Aron, A. T.;
Onak, C. S.;
Ramos-Torres, K. M.;
Paek, J.;
Webster, C. W.;
Feller, M. B.;
Chang, C. J.
"Copper is an endogenous modulator of neural circuit spontaneous activity",
Proc. Natl. Acad. Sci. USA
2014,
111,
16280-16285.
[html]
[pdf]
[LBNL News Story]
[C&E News Story]
[R&D Magazine News Story]
129.
Hong-Hermesdorf, A.;
Miethke, M.;
Gallaher, S. D.;
Kropat, J.;
Dodani, S. C.;
Chan, J.;
Barupala, D.;
Domaille, D. W.;
Shirasaki, S. I.;
Loo, J. A.;
Weber, P. K.;
Pett-Ridge, J.;
Stemmler, T. L.;
Chang, C. J.;
Merchant, S. S.
"Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas",
Nature Chem. Biol.
2014,
10,
1034-1042.
[html]
[pdf]
128.
Carroll, V.;
Michel, B. W.;
Blecha, J.;
VanBrocklin, H.;
Keshari, K.;
Wilson, D.;
Chang, C. J.
"A Boronate-Caged [18F]FLT Probe for Hydrogen Peroxide Detection Using Positron Emission Tomography",
J. Am. Chem. Soc.
2014,
136,
14742-14745.
[html]
[pdf]
127.
Yang, M.;
Haase, A. D.;
Huang, F.;
Coulis, G.;
Rivera, K. D.;
Dickinson, B. C.;
Chang, C. J.;
Pappin, D. J.;
Neubert, T. A.;
Hannon, G. J.;
Boivin, B.;
Tonks, N. K.
"Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence",
Mol. Cell
2014,
55,
782-790.
[html]
[pdf]
126.
Sanders, L. H.;
McCoy, J.;
Hu, X.;
Mastroberardino, P. G.;
Dickinson, B. C.;
Chang, C. J.;
Chu, C. T.;
Van Houten, B.;
Greenamyre, J. T.
"Mitochondrial DNA damage: Molecular marker of vulnerable nigral neurons in Parkinson's disease",
Neurobiol. Dis.
2014,
70,
214-223.
[html]
[pdf]
125.
King, A. E.;
Nippe, M.;
Atanasov, M.;
Chantarojsiri, T.;
Wray, C.;
Bill, E.;
Neese, f.;
Long, J. R.;
Chang, C. J.
"A Well-Defined Terminal Vanadium(III) Oxo Complex",
Inorg. Chem.
2014,
53,
11388-11395.
[html]
[pdf]
124.
Polishchuk, E. V.;
Concilli, M.;
Iacobacci, S.;
Chesi, G.;
Pastore, N.;
Piccolo, P.;
Paladino, S.;
Baldantoni, D.;
van IJzendoorn, S. C. D.;
Chan, J.;
Chang, C. J.;
Amoresano, A.;
Pane, F.;
Pucci, P.;
Tarallo, A.;
Parenti, G.;
Brunetti-Pierri, N.;
Settembre, C.;
Ballabio, A.;
Polishchuk, R. S.
"Wilson Disease Protein ATP7B Utilizes Lysosomal Exocytosis to Maintain Copper Homeostasis",
Dev. Cell
2014,
29,
686-700.
[html]
[pdf]
123.
Kashyap, D. R.;
Rompca, A.;
Gaballa, A.;
Helmann, J. D.;
Chan, J.;
Chang, C. J.;
Hozo, I.;
Gupta, D.;
Dziarski, R.
"Peptidoglycan Recognition Proteins Kill Bacteria by Inducing Oxidative, Thiol, and Metal Stress",
PLoS Pathog.
2014,
10,
e1004280.
[html]
[pdf]
122.
Basu, S.;
Rajakaruna, S.;
Dickinson, B. C.;
Chang, C. J.;
Menko, A. S.
"Endogenous hydrogen peroxide production in the epithelium of the developing embryonic lens",
Mol. Vis.
2014,
20,
458.
[html]
[pdf]
121.
Banerjee, J.;
Das Ghatak, P.;
Roy, S.;
Khanna, S.;
Sequin, E. K.;
Bellman, K.;
Dickinson, B. C.;
Suri, P.;
Subramaniam, V. V.;
Chang, C. J.;
Sen, C. K.
"Improvement of Human Keratinocyte Migration by a Redox Active Bioelectric Dressing",
PLoS One
2014,
9,
e89239.
[html]
[pdf]
120.
Khnayzer, R. S.;
Thoi, V. S.;
Nippe, M.;
King, A. E.;
Jurss, J. W.;
El Roz, K. A.;
Long, J. R.;
Chang, C. J.;
Castellano, F. N.
"Towards a comprehensive understanding of visible-light photogeneration of hydrogen from water using cobalt(II) polypyridyl catalysts",
Energy Environ. Sci.
2014,
7,
1477-1488.
[html]
[pdf]
119.
Huang, C. P.;
Fofana, M.;
Chan, J.;
Chang, C. J.;
Howell, S. B.
"Copper transporter 2 regulates intracellular copper and sensitivity to cisplatin",
Metallomics
2014,
6,
654-661.
[html]
[pdf]
118.
Boivin, B.;
Chaudhary, F.;
Dickinson, B. C.;
Haque, A.;
Pero, S. C.;
Chang, C. J.;
Tonks, N. K.
"Receptor Protein-tyrosine Phosphatase α Regulates Focal Adhesion Kinase Phosphorylation and ErbB2 Oncoprotein-mediated Mammary Epithelial Cell Motility",
J. Biol. Chem.
2013,
288,
36926-36935.
[html]
[pdf]
117.
Sun, Y.;
Liu, C.;
Grauer, D. C.;
Yano, J.;
Long, J. R.;
Yang, P.;
Chang, C. J.
"Electrodeposited Cobalt-Sulfide Catalyst for Electrochemical and Photoelectrochemical Hydrogen Generation from Water",
J. Am. Chem. Soc.
2013,
135,
17699-17702.
[html]
[pdf]
116.
Au-Yeung, H. Y.;
Chan, J.;
Chantarojsiri, T.;
Chang, C. J.
"Molecular Imaging of Labile Iron(II) Pools in Living Cells with a Turn-On Fluorescent Probe",
J. Am. Chem. Soc.
2013,
135,
15165-15173.
[html]
[pdf]
115. Nippe, M.; Khnayzer, R. S.; Panetier, J. A.; Zee, D. Z.; Olaiya, B. S.; Head-Gordon, M.; Chang, C. J.; Castellano, F. N.; Long, J. R.
"Catalytic Proton Reduction with Transition Metal Complexes of the Redox-active Ligand bpy2PYMe",
Chem. Sci.
2013,
4,
3934-3945.
[html]
[pdf]
114.
Thoi, V. S.;
Kornienko, N.;
Margarit, C. G.;
Yang, P.;
Chang, C. J.
"Visible-Light Photoredox Catalysis: Selective Reduction of Carbon Dioxide to Carbon Monoxide by a Nickel N-Heterocyclic Carbene-Isoquinoline Complex",
J. Am. Chem. Soc.
2013,
135,
14413-14424.
[html]
[pdf]
113.
Lin, V. S.; Dickinson, B. C.; Chang, C. J.
"Boronate-Based Fluorescent Probes: Imaging Hydrogen Peroxide in Living Systems",
Meth. Enzymol.
2013,
526,
19-43
(Chapter 2 in Hydrogen Peroxide and Cell Signaling, Part A).
[html]
112.
Dickinson, B. C.; Lin, V. S.; Chang, C. J.
"Preparation and Use of MitoPY1 for Imaging Hydrogen Peroxide in Mitochondria of Live Cells",
Nature Protoc.
2013,
8,
1249-1259.
[pdf]
[html]
111.
Kashif, M. K.;
Nippe, M.;
Duffy, N. W.;
Forsyth, C. M.;
Chang, C. J.;
Long, J. R.;
Spiccia, L.;
Bach, U.;
"Stable Dye-Sensitized Solar Cell Electrolytes Based on Cobalt(II)/(III) Complexes of a Hexadentate Pyridyl Ligand",
Angew. Chem. Int. Ed.
2013,
52,
5527-5531.
[html]
[pdf]
110.
Lin, V. S.; Lippert, A. R.; Chang, C. J.
"Cell-trappable Fluorescent Probes for Endogenous Hydrogen Sulfide Signaling and Imaging H2O2-Dependent H2S Production",
Proc. Natl. Acad. Sci. USA
2013,
110,
7131-7135.
[pdf]
[html]
[C&E News]
[CRT Spotlight]
[Faculty of 1000 Recommendation]
109.
King, A. E.; Surendranath, Y.; Piro, N. A.; Bigi, J. P.; Long, J. R.; Chang, C. J.
"A Mechanistic Study of Proton Reduction Catalyzed by a Pentapyridine Cobalt Complex: Evidence for Involvement of an Anation-Based Pathway",
Chem. Sci.
2013,
4,
1578-1587.
[pdf]
[html]
108.
Harris, J. M.;
Esain, V.;
Frechette, G. M.;
Harris, L. J.;
Cox, A. G.;
Cortes, M.;
Garnaas, M. K.;
Carroll, K. J.;
Cutting, C. C.;
Khan, T.;
Elks, P. M.;
Renshaw, S. A.;
Dickinson, B. C.;
Chang, C. J.;
Murphy, M. P.;
Paw, B. H.;
Vander Heiden, M. G.;
Goessling, W.;
North, T. E.;
"Glucose Metabolism Impacts the Spatiotemporal Onset and Magnitude of HSC Induction in Vivo",
Blood
2013,
121,
2483-2493.
[pdf]
[html]
107.
Thoi, V. S.; Sun, Y.; Long, J. R.; Chang, C. J.
"Complexes of earth-abundant metals for catalytic electrochemical hydrogen generation under aqueous conditions",
Chem. Soc. Rev.
2013,
42,
2388-2400.
[pdf]
[html]
106.
Van de Bittner, G. C.; Bertozzi, C. R.; Chang, C. J.
"Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation",
J. Am. Chem. Soc.
2013,
135,
1783-1795.
[pdf]
[html]
105.
Sun, Y.; Sun, J.; Long, J. R.; Yang, P.; Chang, C. J.
"Photocatalytic generation of hydrogen from water using a cobalt pentapyridine complex in combination with molecular and semiconductor nanowire photosensitizers",
Chem. Sci.
2013,
4,
118-124.
[pdf]
[html]
104.
Sakai, J.; Li, J.; Subramanian, K. K.; Mondal, S.; Bajrami, B.; Hattori, H.; Jia, Y.; Dickinson, B. C.; Zhong, J.; Ye, K.; Chang, C. J.; Ho, Y.-S.; Zhou, J.; Luo, H. R.
"Reactive Oxygen Species-Induced Actin Glutathionylation Controls Actin Dynamics in Neutrophils",
Immunity
2012,
37,
1037-1049.
[html]
103.
Chan, J.; Dodani, S. C.; Chang, C. J.
"Reaction-based small-molecule fluorescent probes for chemoselective bioimaging",
Nature Chem.
2012,
4,
973-984.
[pdf]
[html]
102.
Kashif, M. K.; Axelson, J. C.; Duffy, N. W.; Forsyth, C. M.; Chang, C.J.; Long, J. R.; Spiccia, L.; Bach, U.
"A New Direction in Dye-Sensitized Solar Cells Redox Mediator Development: In Situ Fine-Tuning of the Cobalt(II)/(III) Redox Potential through Lewis Base Interactions",
J. Am. Chem. Soc.
2012,
134,
16646-16653.
[pdf]
[html]
101.
Lin, V. S.; Chang, C. J.
"Fluorescent probes for sensing and imaging biological hydrogen sulfide",
Curr. Opin. Chem. Biol.
2012,
16,
595-601.
[pdf]
[html]
100.
Michel, B. W.; Lippert, A. R.; Chang, C. J.
"A Reaction-Based Fluorescent Probe for Selective Imaging of Carbon Monoxide in Living Cells Using a Palladium-Mediated Carbonylation",
J. Am. Chem. Soc.
2012,
134,
15668-15671.
[pdf]
[html]
[C&E News]
99.
Harman, W. H.; Lichterman, M. F.; Piro, N. A.; Chang, C. J.
"Well-Defined Vanadium Organoazide Complexes and Their Conversion to Terminal Vanadium Imides: Structural Snapshots and Evidence for a Nitrene Capture Mechanism",
Inorg. Chem.
2012,
51,
10037-10042.
[pdf]
[html]
98.
Hu, C.; Mori, T.; Lu, Y.; Guo, Q.; Sun, Y.; Yoneki, Y.; Ohsaki, Y.; Nakamichi, T.; Oba, I.; Sato, E.; Ogawa, S.; Dickinson, B. C.; Chang, C. J.; Miyata, T.; Sato, H.; Ito, S.
"Role of specific T-type calcium channel blocker R(-) efonidipine in the regulation of renal medullary circulation",
J. Hypertens.
2012,
30,
1620-1631.
[pdf]
[html]
97.
Woolley, J. F.; Naughton, R.; Stanicka, J.; Gough, D. R.; Bhatt, L.; Dickinson, B. C.; Chang, C. J.; Cotter, T. G.
"H2O2 Production Downstream of FLT3 Is Mediated by p22phox in the Endoplasmic Reticulum and Is Required for STAT5 Signalling",
PLoS One
2012,
7,
e34050.
[pdf]
[html]
96.
Au-Yeung, H. Y.; New, E. J.; Chang, C. J.
"A selective reaction-based fluorescent probe for detecting cobalt in living cells",
Chem. Commun.
2012,
48,
5268-5270.
[pdf]
[html]
95.
Thoi, V. S.; Karunadasa, H. I.; Surendranath, Y.; Long, J. R.; Chang, C. J.;
"Electrochemical generation of hydrogen from acetic acid using a molecular molybdenum-oxo catalyst",
Energy Environ. Sci.
2012,
5,
7762-7770.
[pdf]
[html]
94.
Que, E. L.; New, E. J.; Chang, C. J.
"A cell-permeable gadolinium contrast agent for magnetic resonance imaging of copper in a Menkes disease model",
Chem. Sci.
2012,
3,
1829-1834.
[pdf]
[html]
93.
Sundstrom, E. J.; Yang, X.; Thoi, V. S.; Karunadasa, H. I.; Chang, C. J.; Long, J. R.; Head-Gordon, M.
"Computational and Experimental Study of the Mechanism of Hydrogen Generation from Water by a Molecular Molybdenum-Oxo Electrocatalyst",
J. Am. Chem. Soc.
2012,
134,
5233-5242.
[pdf]
[html]
92.
Cusick, K. D.; Minkin, Jr., S. C.; Dodani, S. C.; Chang, C. J.; Wilhelm, S. W.; Sayler G. S.
"Inhibition of Copper Uptake in Yeast Reveals the Copper Transporter Ctr1p As a Potential Molecular Target of Saxitoxin",
Environ. Sci. Technol.
2012,
46,
2959-2966.
[pdf]
[html]
91.
Karunadasa, H. I.; Montalvo, E.; Sun, Y.; Majda, M.; Long, J. R.; Chang, C. J.
"A Molecular MoS2 Edge Site Mimic for Catalytic Hydrogen Generation",
Science
2012,
335,
698-702.
[pdf]
[html]
[UC Berkeley press release]
[LBNL press release]
[Daily Cal article]
[C&E News article]
90.
Hirayama, T.; Van de Bittner, G. C.; Gray, L. W.; Lutsenko, S.; Chang, C. J.
"Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model",
Proc. Natl. Acad. Sci. USA
2012,
109,
2228-2233.
[pdf]
[html]
89.
Zadrozny, J. M.; Liu, J.; Piro, N. A.; Chang, C. J.; Hill, S.; Long J. R.
"Slow magnetic relaxation in a pseudotetrahedral cobalt(II) complex with easy-plane anisotropy",
Chem. Commun.
2012,
48,
3927-3929.
[pdf]
[html]
88.
Bigi, J. P.; Harman, W. H.; Lassalle-Kaiser, B.; Robles, D. M.; Stich, T. A.; Yano, J.; Britt, R. D.; Chang C. J.
"A High-Spin Iron(IV)-Oxo Complex Supported by a Trigonal Nonheme Pyrrolide Platform",
J. Am. Chem. Soc.
2012,
134,
1536-1542.
[pdf]
[html]
87.
Ohsaki, Y.; O'Connor, P.; Mori, T.; Ryan, R. P.; Dickinson, B. C.; Chang, C. J.; Lu, Y.; Ito, S.; Cowley Jr., A. W.
"Increase of Sodium Delivery Stimulates the Mitochondrial Respiratory Chain H2O2 Production in Rat Renal Medullary Thick Ascending Limb",
Am. J. Physiol. Renal. Physiol.
2012,
302,
F95-F102.
[pdf]
[html]
86.
Wrighton, K. C.; Thrash, J. C.; Melnyk, R. A.; Bigi, J. P.; Byrne-Bailey, K. G. ; Remis, J. P.; Schichnes, D.; Auer, M.; Chang, C. J.; Coates, J. D.
"Evidence for Direct Electron Transfer by a Gram-Positive Bacterium Isolated from a Microbial Fuel Cell",
Appl. Environ. Microbiol.
2011,
77,
7633-7639.
[pdf]
[html]
85.
Beaudoin, J.; Ioannoni, R.; López-Maury, L.; Bähler, J.; Ait-Mohand, S.; Guérin, B.; Dodani, S. C.; Chang, C. J.; Labbé, S.
"Mfc1 Is a Novel Forespore Membrane Copper Transporter in Meiotic and Sporulating Cells",
J. Biol. Chem.
2011,
286,
34356-34372.
[pdf]
[html]
84.
Dickinson, B. C.; Tang, Y.; Chang, Z.; Chang, C. J.
"A Nuclear-Localized Fluorescent Hydrogen Peroxide Probe for Monitoring Sirtuin-Mediated Oxidative Stress Responses In Vivo",
Chem. Biol.
2011,
18,
943-948.
[pdf]
[html]
83.
Lippert, A. R.; Van de Bittner, G. C.; Chang, C. J.
"Boronate Oxidation as a Bioorthogonal Reaction Approach for Studying the Chemistry of Hydrogen Peroxide in Living Systems",
Acc. Chem. Res.
2011,
44,
793-804.
[pdf]
[html]
82.
Chung, C.; Srikun, D.; Lim, C. S.; Chang, C. J.; Cho, B. R.
"A two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue",
Chem. Commun.
2011,
47,
9618-9620.
[pdf]
[html]
81.
Lu, J.; Esposito, G.; Scuderi, C.; Steardo, L.; Delli-Bovi, L. C.; Hecht, J. L.; Dickinson, B. C.; Chang, C. J.; Mori, T.; Sheen, V.
"S100B and APP Promote a Gliocentric Shift and Impaired Neurogenesis in Down Syndrome Neural Progenitors",
PLoS ONE
2011,
6,
e22126.
[pdf]
[html]
80.
Dickinson, B. C.; Chang, C. J.
"Chemistry and biology of reactive oxygen species in signaling or stress responses",
Nature Chem. Biol.
2011,
7,
504-511.
[pdf]
[html]
79.
Lippert, A. R.; New, E. J.; Chang, C. J.
"Reaction-Based Fluorescent Probes for Selective Imaging of Hydrogen Sulfide in Living Cells",
J. Am. Chem. Soc.
2011,
133,
10078-10080.
[pdf]
[html]
[C&E News]
78.
Sun, Y.; Bigi, J. P.; Piro, N. A.; Tang, M. L.; Long, J. R.; Chang, C. J.
"Molecular Cobalt Pentapyridine Catalysts for Generating Hydrogen from Water",
J. Am. Chem. Soc.
2011,
133,
9212-9215.
[pdf]
[html]
77.
Dodani, S. C.; Leary, S. C.; Cobine, P. A.; Winge, D. R.; Chang, C. J.
"A targetable fluorescent sensor reveals that copper-deficient SCO1 and SCO2 patient cells prioritize mitochondrial copper homeostasis",
J. Am. Chem. Soc.
2011,
133,
8606-8616.
[pdf]
[html]
76.
Thoi, V. S. and Chang, C. J.
"Nickel N-heterocyclic carbene-pyridine complexes that exhibit selectivity for electrocatalytic reduction of carbon dioxide over water",
Chem. Commun.
2011,
47,
6578-6580.
[pdf]
[html]
75.
Harris, T. D.; Soo, H. S.; Chang, C. J.; Long, J. R.
"A cyano-bridged FeIIReIV(CN)2 cluster incorporating two high-magnetic anisotropy building units",
Inorg. Chim. Acta
2011,
369,
91-96
(Special Issue in Honor of Robert G. Bergman).
[pdf]
[html]
74.
Soo, H. S.; Sougrati, M. T.; Grandjean, F.; Long, G. J.; Chang, C. J.
"A seven-coordinate iron platform and its oxo and nitrene reactivity",
Inorg. Chim. Acta
2011,
369,
82-91
(Special Issue in Honor of Robert G. Bergman).
[pdf]
[html]
73.
Murphy, M. P.; Holmgren, A.; Larsson, N.-G.; Halliwell, B.; Chang, C. J.; Kalyanaraman, B.; Rhee, S. G.; Thornalley, P. J.; Partridge, L.; Gems, D.; Nyström, T.; Belousov, V.; Schumacker, P. T.; Winterbourn, C. C.
"Unraveling the Biological Roles of Reactive Oxygen Species",
Cell Metab.
2011,
13,
361-366.
[pdf]
[html]
72.
Dodani, S. C.; Domaille, D. W.; Nam, C. I.; Miller, E. W.; Finney, L. A.; Vogt, S.; Chang, C. J.
"Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy",
Proc. Natl. Acad. Sci. USA
2011,
108,
5980-5985.
[pdf]
[html]
71.
Srikun, D.; Albers, A. E.; Chang, C. J.
"A dendrimer-based platform for simultaneous dual fluorescence imaging of hydrogen peroxide and pH gradients produced in living cells",
Chem. Sci.
2011,
2,
1156-1165.
[pdf]
[html]
70.
Lippert, A. R.; Keshari, K. R.; Kurhanewicz, J.; Chang, C. J.
"A Hydrogen Peroxide-Responsive Hyperpolarized 13C MRI Contrast Agent",
J. Am. Chem. Soc.
2011,
133,
3776-3779.
[pdf]
[html]
69.
Santo, C. E.; Lam, E. W.; Elowsky, C. G.; Quaranta, D.; Domaille, D. W.; Chang, C. J.; Grass, G.
"Bacterial Killing by Dry Metallic Copper Surfaces",
Appl. Environ. Microbiol.
2011,
77,
794-802.
[pdf]
[html]
68.
Quaranta, D.; Krans, T.; Santo, C. E.; Elowsky, C. G.; Domaille, D. W.; Chang, C. J.; Grass, G.
"Mechanisms of Contact-Mediated Killing of Yeast Cells on Dry Metallic Copper Surfaces",
Appl. Environ. Microbiol.
2011,
77,
416-426.
[pdf]
[html]
67.
Piro, N. A., Lichterman, M. F., Harman, W. H., Chang, C. J.
"A Structurally Characterized Nitrous Oxide Complex of Vanadium",
J. Am. Chem. Soc.
2011,
133,
2108-2111.
[pdf]
[html]
66.
Schrag, M.; Crofton, A.; Zabel, M.; Jiffry, A.; Kirsch, D.; Dickson, A.; Mao, X. W.; Vinters, H. V.; Domaille, D. W.; Chang, C. J.; Kirsch, W.
"Effect of cerebral amyloid angiopathy on brain iron, copper, and zinc in Alzheimer's disease",
J. Alzheimers Dis.
2011,
24,
137-149.
[pdf]
[html]
65.
Dickinson, B. C., Peltier, J., Stone, D., Schaffer, D. V., Chang, C. J.
"Nox2 redox signaling maintains essential cell populations in the brain",
Nature Chem. Biol.
2011,
7,
106-112.
[pdf]
[html]
64.
Harman, W. H., Harris, T. D., Freedman, D. E., Fong, H., Chang, A., Rinehart, J. D., Ozarowski, A., Sougrati, M. T., Grandjean, F., Long, G. J., Long, J. R., Chang, C. J.
"Slow Magnetic Relaxation in a Family of Trigonal Pyramidal Iron(II) Pyrrolide Complexes",
J. Am. Chem. Soc.
2010,
132,
18115-18126.
[pdf]
[html]
63.
Van de Bittner, G. C., Dubikovskaya E. A., Bertozzi, C. R., and Chang, C. J.
"In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter",
Proc. Natl. Acad. Sci. USA
2010,
107,
21316-21321.
[pdf]
[html]
[Faculty of 1000 Evaluation]
[LBL Highlight]
62.
Miller, E. W.; Taulet, N.; Onak, C. S.; New, E. J.; Lanselle, J. K.; Smelick, G. S.; Chang, C. J.
"Light-Activated Regulation of Cofilin Dynamics Using a Photocaged Hydrogen Peroxide Generator",
J. Am. Chem. Soc.
2010,
132,
17071-17073.
[pdf]
[html]
61.
Lippert, A. R.; Gschneidtner, T.; Chang, C. J.
"Lanthanide-Based Luminescent Probes for Selective Time-Gated Detection of Hydrogen Peroxide in Water and in Living Cells",
Chem. Commun.
2010,
46,
7510-7512. [pdf]
[html]
60.
Miller, E. W.; Dickinson, B. C.; Chang, C. J.
"Aquaporin-3 Mediates Hydrogen Peroxide Uptake to Regulate Downstream Intracellular Signaling",
Proc. Natl. Acad. Sci. USA
2010,
107,
15681-15686.
[pdf]
[html]
[ACS Chembio Spotlight]
[Faculty of 1000 Evaluation]
59.
Cheng, W.-Y.; Tong, H.; Miller, E. W.; Chang, C. J.; Remington, J.; Zucker, R. M.; Bromberg, P. A.; Samet, J. M.; Hofer, T. P. J.
"An Integrated Imaging Approach to the Study of Oxidative Stress Generation by Mitochondrial Dysfunction in Living Cells",
Environ. Health Perspectives
2010,
118,
902-908.
[pdf]
58.
Karunadasa, H. I.; Chang, C. J.; Long, J. R.
"A Molecular Molybdenum-Oxo Catalyst for Generating Hydrogen from Water",
Nature
2010,
464,
1329-1333.
[pdf]
57.
Dickinson, B. C.; Huynh, C.; Chang, C. J.
"A Palette of Fluorescent Probes with Varying Emission Colors for Imaging Hydrogen Peroxide Signaling in Living Cells",
J. Am. Chem. Soc.
2010,
132,
5906-5915.
[pdf]
[html]
56.
Srikun, D.; Albers, A. E.; Nam, C. I.; Iavarone, A. T.; Chang, C. J.
"Organelle-Targetable Fluorescent Probes for Imaging Hydrogen Peroxide in Living Cells via SNAP-Tag Protein Labeling",
J. Am. Chem. Soc.
2010,
132,
4455-4465.
[pdf]
55. Freedman, D. E.; Harman, W. H.; Harris, T. D.; Long, G. J.; Chang, C. J.; Long, J. R. "Slow Magnetic Relaxation in a High-Spin Iron(II) Complex", J. Am. Chem. Soc. 2010, 132, 1224-1225. [pdf]
54. Domaille, D. W.; Zeng, L.; Chang, C. J. "Visualizing Ascorbate-Triggered Release of Labile Copper within Living Cells using a Ratiometric Fluorescent Sensor", J. Am. Chem. Soc. 2010, 132, 1194-1195. [pdf]
53. Bigi, J. P.; Hanna, T. E.; Harman, W. H.; Chang, A.; Chang, C. J. "Electrocatalytic Reduction of Protons to Hydrogen by a Water-Compatible Cobalt Polypyridyl Platform", Chem. Commun. 2010, 46, 958-960. [pdf]
52. Que, E. L.; Gianolio, E.; Baker, S. L.; Aime, S.; Chang, C. J. "A Copper-Activated Magnetic Resonance Imaging Contrast Agent with Improved Turn-On Relaxivity Response and Anion Compatibility", Dalton Trans. 2010, 39, 469-476 (Special Issue). [pdf]
51. Dickinson, B. C.; Srikun, D.; Chang, C. J. "Mitochondrial-Targeted Fluorescent Probes for Reactive Oxygen Species", Curr. Opin. Chem. Biol. 2010, 14, 50-56. [pdf]
50. Que, E. L.; Chang, C. J. "Responsive Magnetic Resonance Imaging Contast Agents as Chemical Sensors for Metals in Biology and Medicine", Chem. Soc. Rev. 2010, 39, 51-60. [pdf]
49. Dodani, S. C.; He, Q.; Chang, C. J. "A Turn-On Fluorescent Sensor for Detecting Nickel in Living Cells", J. Am. Chem. Soc. 2009, 131, 18020-18021. [pdf]
48. Soo, H. S.; Komor, A. C.; Iavarone, A. T.; Chang, C. J. "A Hydrogen-Bonded Facilitated Cycle for Oxygen Reduction by an Acid- and Base-Compatible Iron Platform", Inorg. Chem. 2009, 48, 10024-10035. [pdf]
47. Bao, L.; Avshalumov, M. V.; Miller, E. W.; Chang, C. J.; Rice, M. E. J. "Mitochondria are the Source of Hydrogen Peroxide for Dynamic Brain-Cell Signaling", J. Neurosci. 2009, 29, 9002-9010. [pdf]
46. Que, E. L.; Gianolio, E.; Baker, S. L.; Wong, A. P.; Aime, S.; Chang, C. J. "Copper-Responsive Magnetic Resonance Imaging Contrast Agents", J. Am. Chem. Soc. 2009, 131, 8527-8536. [pdf]
45. Albers, A. E.; Dickinson, B. C.; Miller, E. W.; Chang, C. J."A Red-Emitting Naphthofluorescein-Based Fluorescent Probe for Selective Detection of Hydrogen Peroxide in Living Cells", Bioorg. Med. Chem. Lett. 2008, 18, 5948-5950 (Special Issue in Honor of Benjamin F. Cravatt). [pdf]
44. Dickinson, B. C.; Chang, C. J."A Targetable Fluorescent Probe for Imaging Hydrogen Peroxide in the Mitochondria of Living Cells", J. Am. Chem. Soc. 2008, 130, 9638-9639. [pdf]
[C&E News]
[Angewandte Chemie Highlight]
43. Miller, E. W.; He, Q.; Chang, C. J. "Preparation and Use of Leadfluor-1, a Synthetic Fluorophore for Live-Cell Lead Imaging", Nature Protocols 2008, 3, 777-783. [pdf]
42. Que, E. L.; Domaille, D. W.; Chang, C. J. "Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging", Chem. Rev. 2008, 108, 1517-1549. [pdf]
41. Srikun, D.; Miller, E. W.; Domaille, D. W.; Chang, C. J."An ICT-Based Approach to Ratiometric Fluorescence Imaging of Hydrogen Peroxide Produced in Living Cells", J. Am. Chem. Soc. 2008, 130, 4596-4597. [pdf]
40. Domaille, D. W.; Que, E. L.; Chang, C. J. "Synthetic Fluorescent Sensors for Studying the Cell Biology of Metals", Nature Chem. Biol. 2008, 4, 168-175. [pdf]
39. Harman, W. H.; Chang, C. J. "N2O Activation and Oxidation Reactivity from a Non-Heme Iron Pyrrole Platform", J. Am. Chem. Soc. 2007, 129, 15128-15129. [pdf]
38. Miller, E. W.; Chang, C. J. "Fluorescent probes for nitric oxide and hydrogen peroxide in cell signaling" Curr. Opin. Chem. Biol. 2007, 11, 620-625. [pdf]
37. Albers, A. E.; Rawls, K. A.; Chang, C. J "Activity-based fluorescent reporters for monoamine oxidases in living cells", Chem. Commun. 2007, 4647-4649. [pdf]
36. Yoon, S.; Miller, E. W.; He, Q.; Do, P. H.; Chang, C. J "A Bright and Specific Fluorescent Sensor for Mercury in Water, Cells, and Tissue", Angew. Chem. Int. Ed. 2007, 46, 6658-6661. [pdf]
35. Miller, E. W.; Tulyathan, O.; Isacoff, E. Y.; Chang, C. J. "Molecular imaging of hydrogen peroxide produced for cell signaling", Nature Chem. Biol. 2007, 3, 263-267. [pdf] [C & E News]
34. Miller, E. W.; Bian, S. X.; Chang, C. J. "A Fluorescent Sensor for Imaging Reversible Redox Cycles in Living Cells", J. Am. Chem. Soc. 2007, 129, 3458-3459. [pdf]
33. Que, E. L.; Chang, C. J. "A Smart Magnetic Resonance Contrast Agent for Selective Copper Sensing", J. Am. Chem. Soc. 2006, 128, 15942-15943. [pdf]
32. Miller, E. W.; Zeng, L.; Domaille, D. W.; Chang, C. J. "Preparation and
Use of Coppersensor-1, a Synthetic Fluorophore for Live-Cell Copper Imaging", Nature Protocols 2006, 1, 824-827. [pdf]
31. Albers, A. E.; Okreglak, V. S.; Chang, C. J. "A FRET-Based Approach to Ratiometric Fluorescence Detection of Hydrogen Peroxide", J. Am. Chem. Soc. 2006, 128, 9640-9641. [pdf]
30. He, Q.; Miller, E. W.; Wong, A. P.; Chang, C. J.
"A Selective Fluorescent Sensor for Detecting Lead in Living Cells", J. Am. Chem. Soc. 2006, 128, 9316-9317. [pdf]
29. Zeng, L.; Miller, E. W.; Pralle, A.; Isacoff, E. Y.; Chang, C. J. "A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells", J. Am. Chem. Soc. 2006, 128, 10-11.
[pdf]
28. Miller, E. W.; Albers, A. E.; Pralle, A.; Isacoff, E. Y.; Chang, C. J. "Boronate-Based Fluorescent Probes for Imaging Cellular Hydrogen Peroxide", J. Am. Chem. Soc. 2005, 127, 16652-16659. [pdf]
27. Yoon, S.; Albers, A. E.; Wong, A. P.; Chang, C. J. "Screening Mercury Levels in Fish with a Selective Fluorescent Chemosensor", J. Am. Chem. Soc. 2005, 127, 16030-16031. [pdf] [C&E News]
26. Chang, M. C. Y.; Pralle, A.; Isacoff, E. Y.; Chang, C. J. "A Selective, Cell-Permeable Optical Probe for Hydrogen Peroxide in Living Cells", J. Am. Chem. Soc. 2004, 126, 15392-15393. [html] [C&E News]
25. Chang, C. J.; Lippard, S. J. "Zinc Metalloneurochemistry: Physiology, Pathology, and Probes", In Metal Ions in Life Science: Neurodegenerative Diseases and Metal Ions. 2006, Vol. 1, pp. 321-370.
24. Giblin, L. J.; Chang, C. J.; Bentley, A. F.; Frederickson, C.; Lippard, S. J.; Frederickson, C. J. "Zinc-Secreting Paneth Cells Studied by ZP Fluorescence", J. Histochem. Cytochem. 2006, 54, 311-316.
23. Chang, C. J.; Nolan, E.M.; Jaworski, J.; Okamoto, K.; Hayashi, T.; Sheng, M.; Lippard, S.J. "ZP8, an Improved Neuronal Zinc Sensor of the ZP Family: Application to Imaging Zinc in Hippocampal Slices with Two-Photon Microscopy", Inorg. Chem. 2004, 43, 6774-6779.
22. Chang, C. J.; Loh, Z.-H.; Shi, C.; Anson, F.C. Nocera, D. G. "Targeted Proton Delivery in the Catalyzed Reduction of Oxygen to Water by Bimetallic Pacman Porphyrins", J. Am. Chem. Soc. 2004, 126, 10013-10020.
21. Chang, C. J.; Chang, M.C.Y.; Damrauer, N.H.; Nocera, D.G. "Proton-Coupled Electron Transfer. A Unifying Mechanism for Biological Charge Transport, Amino Acid Radical Initiation and Propagation, and Bond Making/Breaking Reactions of Water and Oxygen", Biochim. Biophys. Acta 2004, 1655, 13-28.
20. Chang, C. J.; Nolan, E.M.; Jaworski, J.; Burdette, S.C.; Sheng, M.; Lippard, S.J. "Bright Fluorescent Chemosensor Platforms for Imaging Endogenous Pools of Neuronal Zinc", Chem. Biol. 2004, 11, 203-210.
19. Chang, C. J.; Jaworski, J.; Nolan, E.M.; Sheng, M.; Lippard, S.J. "A Tautomeric Zinc Sensor for Ratiometric Fluorescence Imaging: Application to Nitric Oxide-Induced Release of Intracellular Zinc", Proc. Natl. Acad. Sci. USA 2004, 101, 1129-1134.
18. Hodgkiss, J.M.; Chang, C. J.; Pistorio, B.J.; Nocera, D. G. "Transient Absorption Studies of the Pacman Effect in Spring-Loaded Diiron(III) mu-Oxo Bisporphyrins", Inorg. Chem. 2003, 42, 8270-8277.
17. Chang, C. J.; Loh, Z.-H.; Deng, Y.; Nocera, D. G. "The Pacman Effect: A Supramolecular Strategy for Controlling the Excited-State Dynamics of Pillared Cofacial Bisporphyrins", Inorg. Chem. 2003, 42, 8262-8269.
16. Chng, L.-L.; Chang, C. J.; Nocera, D. G. "Meso-Tetraaryl Cofacial Bisporphyrins Delivered by Suzuki Cross-Coupling", J. Org. Chem. 2003, 68, 4075-4078.
15. Chng, L.-L.; Chang, C. J.; Nocera, D. G. "Catalytic O-O Activation Chemistry Mediated by Iron Hangman Porphyrins with a Wide Range of Proton-Donating Abilities", Org. Lett. 2003, 5, 2421-2424.
14. Chang, C. J.; Chng, L.-L.; Nocera, D. G. "Proton-Coupled O-O Activation on a Redox Platform Bearing a Hydrogen-Bonded Scaffold", J. Am. Chem. Soc. 2003, 125, 1866-1876.
13. Loh, Z.-H.; Miller, S. E.; Chang, C. J.; Carpenter, S. D.; Nocera, D. G. "Excited State Dynamics of Cofacial Pacman Porphyrins", J. Phys. Chem. A 2002, 106, 11700-11708.
12. Pistorio, B. J.; Chang, C. J.; Nocera, D. G. "A Phototriggered Molecular Spring for Aerobic Catalytic Oxidation Reactions", J. Am. Chem. Soc. 2002, 124, 7884-7885.
11. Chang, C. J.; Baker, E. A.; Pistorio, B. J.; Deng, Y.; Loh, Z.-H.; Miller, S. E.; Carpenter, S. D.; Nocera, D. G. "Structural, Spectroscopic, and Reactivity Comparison of Xanthene- and Dibenzofuran-Bridged Cofacial Bisporphyrins", Inorg. Chem. 2002, 41, 3102-3109.
10. Chang, C. J.; Deng, Y.; Lee, G.-H.; Peng, S.-M.; Yeh, C.-Y.; Nocera, D. G. "A Convergent Synthetic Approach Using Sterically Demanding Aryl-Dipyrrylmethanes for Tuning the Pocket Sizes of Cofacial Bisporphyrins", Inorg. Chem. 2002, 41, 3008-3016.
9. Chang, C. J.; Yeh, C.-Y.; Nocera, D. G. "Porphyrins Bearing Functionalized Xanthene Spacers", J. Org. Chem. 2002, 67, 1403-1406.
8. Chang, C. J.; Brown, J. D. K.; Chang, M. C. Y.; Baker, E. A.; Nocera, D. G. "Electron Transfer in Hydrogen-Bonded Donor-Acceptor Supramolecules", In Electron Transfer in Chemistry, V. Balzani Ed., Wiley-VCH, Weinheim, Germany, 2001, Vol. 3.2.4., p 409-461.
7. Yeh, C.-Y.; Chang, C. J.; Nocera, D. G. "'Hangman' Porphyrins for the Assembly of a Model Heme Water Channel", J. Am. Chem. Soc. 2001, 123, 1513-1514.
6. Chang, C. J.; Deng, Y.; Shi, C.; Chang, C. K.; Anson, F. C.; Nocera, D. G. "Electrocatalytic Four-Electron Reduction of Oxygen to Water by a Highly Flexible Cofacial Cobalt Bisporphyrin", Chem. Commun. 2000, 1355-1356.
5. Chang, C. J.; Deng, Y.; Heyduk, A. F.; Chang, C. K.; Nocera, D. G. "Xanthene-Bridged Cofacial Bisporphyrins", Inorg. Chem. 2000, 39, 959-966.
4. Deng, Y.; Chang, C. J.; Nocera, D. G. "Direct Observation of the 'Pac-Man' Effect from Dibenzofuran-Bridged Cofacial Bisporphyrins" J. Am. Chem. Soc. 2000, 122, 410-411.
3. Chang, C. J.; Connick, W. B.; Low, D. W.; Day, M. W.; Gray, H. B. "Electronic Structures of Nitridomanganese(V) Complexes", Inorg. Chem. 1998, 37, 3107-3110.
2. Chang, C. J.; Labinger, J. A.; Gray, H. B. "Aerobic Epoxidation of Olefins Catalyzed by Electronegative Vanadyl Salen Complexes", Inorg. Chem. 1997, 36, 5927-5930.
1. Chang, C. J.; Low, D. W.; Gray, H. B. "Reversible Nitrogen Atom Transfer between Nitridomanganese(V) and Manganese(III) Schiff-Base Complexes", Inorg. Chem. 1997, 36, 270-271.